Hill, William W; Lim, Emilia L EL; Weeden, Clare E CE; Lee, Claudia C; Augustine, Marcellus M; Chen, Kezhong K; Kuan, Feng-Che FC; Marongiu, Fabio F; Evans, Edward J EJ; Moore, David A DA; Rodrigues, Felipe S FS; Pich, Oriol O; Bakker, Bjorn B; Cha, Hongui H; Myers, Renelle R; van Maldegem, Febe F; Boumelha, Jesse J; Veeriah, Selvaraju S; Rowan, Andrew A; Naceur-Lombardelli, Cristina C; Karasaki, Takahiro T; Sivakumar, Monica M; De, Swapnanil S; Caswell, Deborah R DR; Nagano, Ai A; Black, James R M JRM; Martínez-Ruiz, Carlos C; Ryu, Min Hyung MH; Huff, Ryan D RD; Li, Shijia S; Favé, Marie-Julie MJ; Magness, Alastair A; Suárez-Bonnet, Alejandro A; Priestnall, Simon L SL; Lüchtenborg, Margreet M; Lavelle, Katrina K; Pethick, Joanna J; Hardy, Steven S; McRonald, Fiona E FE; Lin, Meng-Hung MH; Troccoli, Clara I CI; Ghosh, Moumita M; Miller, York E YE; Merrick, Daniel T DT; Keith, Robert L RL; Al Bakir, Maise M; Bailey, Chris C; Hill, Mark S MS; Saal, Lao H LH; Chen, Yilun Y; George, Anthony M AM; Abbosh, Christopher C; Kanu, Nnennaya N; Lee, Se-Hoon SH; McGranahan, Nicholas N; Berg, Christine D CD; Sasieni, Peter P; Houlston, Richard R; Turnbull, Clare C; Lam, Stephen S; Awadalla, Philip P; Grönroos, Eva E; Downward, Julian J; Jacks, Tyler T; Carlsten, Christopher C; Malanchi, Ilaria I; Hackshaw, Allan A; Litchfield, Kevin K; , ; DeGregori, James J; Jamal-Hanjani, Mariam M; Swanton, Charles C
Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.
Translational Lung Cancer Research
Santarpia, Mariacarmela M; Ciappina, Giuliana G; Spagnolo, Calogera Claudia CC; Squeri, Andrea A; Passalacqua, Maria Ilenia MI; Aguilar, Andrés A; Gonzalez-Cao, Maria M; Giovannetti, Elisa E; Silvestris, Nicola N; Rosell, Rafael R
Differential properties of KRAS transversion and transition mutations in non-small cell lung cancer: associations with environmental factors and clinical outcomes.
Osimertinib+Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor Mutated MET-Amplified Non-Small Cell Lung Cancer: TATTON.
Cancer Discovery
Hartmaier, Ryan J RJ; Markovets, Aleksandra A AA; Ahn, Myung Ju MJ; Sequist, Lecia V LV; Han, Ji-Youn JY; Cho, Byoung Chul BC; Yu, Helena A HA; Kim, Sang-We SW; Yang, James Chih-Hsin JC; Lee, Jong-Seok JS; Su, Wu-Chou WC; Kowalski, Dariusz M DM; Orlov, Sergey S; Ren, Song S; Frewer, Paul P; Ou, Xiaoling X; Cross, Darren Ae DA; Kurian, Nisha N; Cantarini, Mireille M; Janne, Pasi A PA
Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC.
Jto Clinical And Research Reports
Schwartzberg, Lee S LS; Li, Gerald G; Tolba, Khaled K; Bourla, Ariel B AB; Schulze, Katja K; Gadgil, Rujuta R; Fine, Alexander A; Lofgren, Katherine T KT; Graf, Ryon P RP; Oxnard, Geoffrey R GR; Daniel, Davey D
Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma.
The Oncologist
Mack, Philip C PC; Klein, Michael I MI; Ayers, Kristin L KL; Zhou, Xiang X; Guin, Sunny S; Fink, Marc M; Rossi, Michael M; Ai-Kateb, Hussam H; O'Connell, Timmy T; Hantash, Feras M FM; Oh, William K WK; Newman, Scott S; Schadt, Eric E EE; Chen, Rong R; Hirsch, Fred R FR
The Genomics of Colorectal Cancer in Populations with African and European Ancestry.
Cancer Discovery
Myer, Parvathi A PA; Lee, Jessica K JK; Madison, Russell W RW; Pradhan, Kith K; Newberg, Justin Y JY; Isasi, Carmen R CR; Klempner, Samuel J SJ; Frampton, Garrett M GM; Ross, Jeffery S JS; Venstrom, Jeffrey M JM; Schrock, Alexa B AB; Das, Sudipto S; Augenlicht, Leonard L; Verma, Amit A; Greally, John M JM; Raj, Srilakshmi M SM; Goel, Sanjay S; Ali, Siraj M SM
p.G12C KRAS mutation prevalence in non-small cell lung cancer: Contribution from interregional variability and population substructures among Hispanics.
Translational Oncology
Ruiz-Patiño, Alejandro A; Rodríguez, July J; Cardona, Andrés F AF; Ávila, Jenny J; Archila, Pilar P; Carranza, Hernán H; Vargas, Carlos C; Otero, Jorge J; Arrieta, Oscar O; Zatarain-Barrón, Lucia L; Sotelo, Carolina C; Ordoñez, Camila C; García-Robledo, Juan Esteban JE; Rojas, Leonardo L; Bermúdez, Maritza M; Gámez, Tatiana T; Mayorga, Diana D; Corrales, Luis L; Martín, Claudio C; Recondo, Gonzalo G; Mas, Luis L; Samtani, Suraj S; Ricaurte, Luisa L; Malapelle, Umberto U; Russo, Alessandro A; Barrón, Feliciano F; Santoyo, Nicolas N; Rolfo, Christian C; Rosell, Rafael R; , ; ,
p.G12C KRAS mutation prevalence in non-small cell lung cancer: Contribution from interregional variability and population substructures among Hispanics.
Translational Oncology
Ruiz-Patiño, Alejandro A; Rodríguez, July J; Cardona, Andrés F AF; Ávila, Jenny J; Archila, Pilar P; Carranza, Hernán H; Vargas, Carlos C; Otero, Jorge J; Arrieta, Oscar O; Zatarain-Barrón, Lucia L; Sotelo, Carolina C; Ordoñez, Camila C; García-Robledo, Juan Esteban JE; Rojas, Leonardo L; Bermúdez, Maritza M; Gámez, Tatiana T; Mayorga, Diana D; Corrales, Luis L; Martín, Claudio C; Recondo, Gonzalo G; Mas, Luis L; Samtani, Suraj S; Ricaurte, Luisa L; Malapelle, Umberto U; Russo, Alessandro A; Barrón, Feliciano F; Santoyo, Nicolas N; Rolfo, Christian C; Rosell, Rafael R; , ; ,
Serum tumor markers for the prediction of concordance between genomic profiles from liquid and tissue biopsy in patients with advanced lung adenocarcinoma.
Translational Lung Cancer Research
Jiao, Xiao-Dong XD; Ding, Li-Ren LR; Zhang, Chuan-Tao CT; Qin, Bao-Dong BD; Liu, Ke K; Jiang, Lian-Ping LP; Wang, Xi X; Lv, Li-Ting LT; Ding, Hao H; Li, Dao-Ming DM; Yang, Hui H; Chen, Xue-Qin XQ; Zhu, Wen-Yu WY; Wu, Ying Y; Ling, Yan Y; He, Xi X; Liu, Jun J; Shao, Lin L; Wang, Hao-Zhe HZ; Chen, Yan Y; Zheng, Jing-Jing JJ; Inui, Naoki N; Zang, Yuan-Sheng YS
Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo.
Cancer Discovery
Foggetti, Giorgia G; Li, Chuan C; Cai, Hongchen H; Hellyer, Jessica A JA; Lin, Wen-Yang WY; Ayeni, Deborah D; Hastings, Katherine K; Choi, Jungmin J; Wurtz, Anna A; Andrejka, Laura L; Maghini, Dylan G DG; Rashleigh, Nicholas N; Levy, Stellar S; Homer, Robert R; Gettinger, Scott N SN; Diehn, Maximilian M; Wakelee, Heather A HA; Petrov, Dmitri A DA; Winslow, Monte M MM; Politi, Katerina K
Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations
Haematologica
Antić, Željko Ž; Yu, Jiangyan J; Van Reijmersdal, Simon V SV; Van Dijk, Anke A; Dekker, Linde L; Segerink, Wouter H WH; Sonneveld, Edwin E; Fiocco, Marta M; Pieters, Rob R; Hoogerbrugge, Peter M PM; Van Leeuwen, Frank N FN; Van Kessel, Ad Geurts AG; Waanders, Esme E; Kuiper, Roland P RP
Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations
Haematologica
Antić, Željko Ž; Yu, Jiangyan J; Van Reijmersdal, Simon V SV; Van Dijk, Anke A; Dekker, Linde L; Segerink, Wouter H WH; Sonneveld, Edwin E; Fiocco, Marta M; Pieters, Rob R; Hoogerbrugge, Peter M PM; Van Leeuwen, Frank N FN; Van Kessel, Ad Geurts AG; Waanders, Esme E; Kuiper, Roland P RP
The Clinical Significance of RAS, PIK3CA, and PTEN Mutations in Non-Small Cell Lung Cancer Using Cell-Free DNA.
Journal Of Clinical Medicine
Chang, Won Jin WJ; Sung, Jae Sook JS; Lee, Sung Yong SY; Kang, Eun Joo EJ; Kwon, Nak-Jung NJ; Kim, Hae Mi HM; Shin, Sang Won SW; Choi, Jung Yoon JY; Choi, Yoon Ji YJ; Kim, Ju Won JW; Park, Kyong Hwa KH; Kim, Yeul Hong YH
Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.
Scientific Reports
Vessies, D C L DCL; Greuter, M J E MJE; van Rooijen, K L KL; Linders, T C TC; Lanfermeijer, M M; Ramkisoensing, K L KL; Meijer, G A GA; Koopman, M M; Coupé, V M H VMH; Vink, G R GR; Fijneman, R J A RJA; van den Broek, D D
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Rabara, Dana D; Tran, Timothy H TH; Dharmaiah, Srisathiyanarayanan S; Stephens, Robert M RM; McCormick, Frank F; Simanshu, Dhirendra K DK; Holderfield, Matthew M
The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.
The Oncologist
Disel, Umut U; Madison, Russell R; Abhishek, Kumar K; Chung, Jon H JH; Trabucco, Sally E SE; Matos, Asli O AO; Frampton, Garrett M GM; Albacker, Lee A LA; Reddy, Venkataprasanth V; Karadurmus, Nuri N; Benson, Adam A; Webster, Jennifer J; Paydas, Semra S; Cabanillas, Ruben R; Nangia, Chaitali C; Ozturk, M A MA; Millis, Sherri Z SZ; Pal, Sumanta K SK; Wilky, Breelyn B; Sokol, Ethan S ES; Gay, Laurie M LM; Soman, Salil S; Ganesan, Shridar S; Janeway, Katherine K; Stephens, Phil J PJ; Zhu, Viola W VW; Ou, Sai-Hong Ignatius SI; Lovly, Christine M CM; Gounder, Mrinal M; Schrock, Alexa B AB; Ross, Jeffrey S JS; Miller, Vincent A VA; Klempner, Samuel J SJ; Ali, Siraj M SM
Impact of Genetics on Neoadjuvant Therapy with Complete Pathological Response in Metastatic Colorectal Cancer: Case Report and Review of the Literature.
Balkan Journal Of Medical Genetics : Bjmg
Bulajic, P P; Bidzic, N N; Djordjevic, V V; Ceranic, Μ Μ; Βasaric, D D; Pesic, V V; Djordjevic-Pesic, J J
Genomic Common Data Model for Seamless Interoperation of Biomedical Data in Clinical Practice: Retrospective Study.
Journal Of Medical Internet Research
Shin, Seo Jeong SJ; You, Seng Chan SC; Park, Yu Rang YR; Roh, Jin J; Kim, Jang-Hee JH; Haam, Seokjin S; Reich, Christian G CG; Blacketer, Clair C; Son, Dae-Soon DS; Oh, Seungbin S; Park, Rae Woong RW
Detection of somatic variants and EGFR mutations in cell-free DNA from non-small cell lung cancer patients by ultra-deep sequencing using the ion ampliseq cancer hotspot panel and droplet digital polymerase chain reaction.
Oncotarget
Sung, Jae Sook JS; Chong, Hyon Yong HY; Kwon, Nak-Jung NJ; Kim, Hae Mi HM; Lee, Jong Won JW; Kim, Boyeon B; Lee, Saet Byeol SB; Park, Chang Won CW; Choi, Jung Yoon JY; Chang, Won Jin WJ; Choi, Yoon Ji YJ; Lee, Sung Yong SY; Kang, Eun Joo EJ; Park, Kyong Hwa KH; Kim, Yeul Hong YH
[Advances of the Role of Lung Cancer Driver Gene and PD-1/PD-L1 Pathway Interaction in the Tumorigenesis and Progression of Non-small Cell Lung Cancer].
Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Shi, Yan Y; Lv, Wang W; Wang, Luming L; Hu, Jian J
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.
Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Drug-sensitive FGFR3 mutations in lung adenocarcinoma.
Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Chandrani, P P; Prabhash, K K; Prasad, R R; Sethunath, V V; Ranjan, M M; Iyer, P P; Aich, J J; Dhamne, H H; Iyer, D N DN; Upadhyay, P P; Mohanty, B B; Chandna, P P; Kumar, R R; Joshi, A A; Noronha, V V; Patil, V V; Ramaswamy, A A; Karpe, A A; Thorat, R R; Chaudhari, P P; Ingle, A A; Choughule, A A; Dutt, A A
Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer.
Molecular Medicine (Cambridge, Mass.)
Dono, Mariella M; Massucco, Carlotta C; Chiara, Silvana S; Sonaglio, Claudia C; Mora, Marco M; Truini, Anna A; Cerruti, Giannamaria G; Zoppoli, Gabriele G; Ballestrero, Alberto A; Truini, Mauro M; Ferrarini, Manlio M; Zupo, Simona S