Publications:

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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm

Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y

Publication Date: 2023-06

Variant appearance in text: KRAS: G13V

PubMed Link: 37250144

Variant Present in the following documents:

• Main text
• MCO2-4-e285.pdf

View BVdb publication page

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Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology

Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2023-04-28

Variant appearance in text: KRAS: G13V

PubMed Link: 37207265

Variant Present in the following documents:

• Main text
• nihpp-2023.04.28.536249v1.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: KRAS: G13V

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: KRAS: Gly13Val

PubMed Link: 37004022

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of DNA Promoter Methylation and BRAF Mutation in Thyroid Cancer.

Current Oncology (Toronto, Ont.)

Jasmine, Farzana F; Aschebrook-Kilfoy, Briseis B; Rahman, Mohammad M MM; Zaagman, Garrett G; Grogan, Raymon H RH; Kamal, Mohammed M; Ahsan, Habibul H; Kibriya, Muhammad G MG

Publication Date: 2023-03-02

Variant appearance in text: rs112445441

PubMed Link: 36975440

Variant Present in the following documents:

• Main text
• curroncol-30-00227.pdf

View BVdb publication page

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Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.

Cancer Research Communications

Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J

Publication Date: 2022-10

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 36969747

Variant Present in the following documents:

• crc-22-0258-s09.xlsx, sheet 1
• crc-22-0258-s08.xlsx, sheet 1

View BVdb publication page

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KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences

Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN

Publication Date: 2023-03-02

Variant appearance in text: KRAS: G13V

PubMed Link: 36902296

Variant Present in the following documents:

• ijms-24-04868.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: KRAS: 38G>T; Gly13Val

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Mutations matter: An observational study of the prognostic and predictive value of KRAS mutations in metastatic colorectal cancer.

Frontiers In Oncology

Lavacchi, Daniele D; Fancelli, Sara S; Roviello, Giandomenico G; Castiglione, Francesca F; Caliman, Enrico E; Rossi, Gemma G; Venturini, Jacopo J; Pellegrini, Elisa E; Brugia, Marco M; Vannini, Agnese A; Bartoli, Caterina C; Cianchi, Fabio F; Pillozzi, Serena S; Antonuzzo, Lorenzo L

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 36523988

Variant Present in the following documents:

• Main text
• fonc-12-1055019.pdf

View BVdb publication page

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Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.

Molecular Oncology

Chen, Tianwei T; Zhang, Xilin X; Ding, Xufen X; Feng, Jing J; Zhang, Xueli X; Xie, Dong D; Wang, Xiang X

Publication Date: 2022-11-30

Variant appearance in text: KRAS: G13V

PubMed Link: 36453019

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Transcriptome and Methylome Study Comparing Tissues of Early and Late Onset Colorectal Carcinoma.

International Journal Of Molecular Sciences

Kibriya, Muhammad G MG; Raza, Maruf M; Quinn, Anthony A; Kamal, Mohammed M; Ahsan, Habibul H; Jasmine, Farzana F

Publication Date: 2022-11-17

Variant appearance in text: rs112445441

PubMed Link: 36430738

Variant Present in the following documents:

• ijms-23-14261.pdf

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KRAS: G13V

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 36344948

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10235.pdf

View BVdb publication page

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 36333792

Variant Present in the following documents:

• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology

Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W

Publication Date: 2022

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 36238300

Variant Present in the following documents:

• Table_1.xlsx, sheet 4

View BVdb publication page

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: KRAS: G13V

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1
• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1

View BVdb publication page

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A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers-Analytical validation and performance evaluation with clinical samples.

Frontiers In Molecular Biosciences

Ng, Cedric Chuan-Young CC; Lim, Sandy S; Lim, Abner Herbert AH; Md Nasir, Nur Diyana ND; Zhang, Jingxian J; Rajasegaran, Vikneswari V; Lee, Jing Yi JY; Kok, Jessica Sook Ting JST; Thike, Aye Aye AA; Lim, Johnathan Xiande JX; Weng, Ruifen R; Yee, Sidney S; Choudhury, Yukti Y; Chan, Jason Yongsheng JY; Tan, Puay Hoon PH; Tan, Min-Han MH; Teh, Bin Tean BT

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 36213130

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 11

View BVdb publication page

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EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine

Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W

Publication Date: 2022-09-19

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 36123678

Variant Present in the following documents:

• 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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SNPMap-An integrated visual SNP interpretation tool.

Frontiers In Genetics

Liu, Miaosen M; Yang, Jian J; Duan, Huilong H; Yu, Lan L; Wu, Dingwen D; Li, Haomin H

Publication Date: 2022

Variant appearance in text: rs112445441

PubMed Link: 36061173

Variant Present in the following documents:

• Main text
• fgene-13-985500.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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A potent tumor-selective ERK pathway inactivator with high therapeutic index.

Pnas Nexus

Zuo, Zehua Z; Liu, Jie J; Sun, Zhihao Z; Silverstein, Rachel R; Zou, Meijuan M; Finkel, Toren T; Bugge, Thomas H TH; Leppla, Stephen H SH; Liu, Shihui S

Publication Date: 2022-07

Variant appearance in text: KRAS: G13V

PubMed Link: 35899070

Variant Present in the following documents:

• pgac104.pdf

View BVdb publication page

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Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC), the same or different entities?

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

White, Valerie A VA; Hyrcza, Martin D MD; Lennerz, Jochen K JK; Thierauf, Julia J; Lokuhetty, Dilani D; Cree, Ian A IA; Indave, Blanca Iciar BI

Publication Date: 2022-10

Variant appearance in text: KRAS: G13V

PubMed Link: 35871081

Variant Present in the following documents:

• 41379_2022_1100_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Non-small-cell lung cancer: how to manage MET exon 14 skipping mutant disease.

Drugs In Context

Blaquier, Juan Bautista JB; Recondo, Gonzalo G

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 35855460

Variant Present in the following documents:

• Main text
• dic-2022-2-2.pdf

View BVdb publication page

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Coexistence of two missense mutations in the KRAS gene in adenocarcinoma of the lung: a possible indicator of poor prognosis.

Pathologica

Spinelli, Manuela M; Du Parcq, Persephone P; Gupta, Nandita N; Khorashad, Jamshid J; Viola, Patrizia P

Publication Date: 2022-06

Variant appearance in text: KRAS: 38G>T

PubMed Link: 35775708

Variant Present in the following documents:

• Main text
• pathol-2022-03-221.pdf

View BVdb publication page

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Somatic targeted mutation profiling of colorectal cancer precursor lesions.

Bmc Medical Genomics

Dos Santos, Wellington W; Dos Reis, Mariana Bisarro MB; Porto, Jun J; de Carvalho, Ana Carolina AC; Matsushita, Marcus M; Oliveira, Gabriela G; Syrjänen, Kari K; Reis, Rui Manuel RM; Guimarães, Denise Peixoto DP

Publication Date: 2022-06-28

Variant appearance in text: rs112445441

PubMed Link: 35761395

Variant Present in the following documents:

• 12920_2022_1294_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: KRAS: G13V

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Molecular Signatures of KRAS-Mutated Lung Adenocarcinoma: Analysis of Concomitant EGFR, ALK, STK11, and PD-L1 Status.

Clinical Pathology (Thousand Oaks, Ventura County, Calif.)

Hsu, Jim J; Annunziata, Joseph F JF; Burns, Ethan E; Bernicker, Eric H EH; Olsen, Randall J RJ; Thomas, Jessica S JS

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 35634237

Variant Present in the following documents:

• Main text
• 10.1177_2632010X221102054.pdf

View BVdb publication page

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Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer

Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E

Publication Date: 2022-05-03

Variant appearance in text: rs112445441

PubMed Link: 35505283

Variant Present in the following documents:

• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 3
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 7
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 9
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 5
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 8
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 4

View BVdb publication page

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Non-canonical genomic driver mutations of urethane carcinogenesis.

Plos One

Li, Siqi S; Counter, Christopher M CM

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 35482806

Variant Present in the following documents:

• pone.0267147.pdf

View BVdb publication page

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Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics

Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R

Publication Date: 2022-04-25

Variant appearance in text: KRAS: 38G>T; G13V

PubMed Link: 35468810

Variant Present in the following documents:

• 12920_2022_1235_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: G13V

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

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A saturation-mutagenesis analysis of the interplay between stability and activation in Ras.

Elife

Hidalgo, Frank F; Nocka, Laura M LM; Shah, Neel H NH; Gorday, Kent K; Latorraca, Naomi R NR; Bandaru, Pradeep P; Templeton, Sage S; Lee, David D; Karandur, Deepti D; Pelton, Jeffrey G JG; Marqusee, Susan S; Wemmer, David D; Kuriyan, John J

Publication Date: 2022-03-11

Variant appearance in text: KRAS: G13V

PubMed Link: 35272765

Variant Present in the following documents:

• elife-76595.pdf

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: KRAS: Gly13Val

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1

View BVdb publication page

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Concomitant KRAS mutations attenuate sensitivity of non-small cell lung cancer cells to KRAS G12C inhibition.

Scientific Reports

Vaclova, Tereza T; Chakraborty, Atanu A; Sherwood, James J; Ross, Sarah S; Carroll, Danielle D; Barrett, J Carl JC; Downward, Julian J; de Bruin, Elza C EC

Publication Date: 2022-02-17

Variant appearance in text: KRAS: G13V

PubMed Link: 35177674

Variant Present in the following documents:

• 41598_2022_6369_MOESM1_ESM.pdf

View BVdb publication page

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Prognostic Impact of Tumor Budding on Moroccan Colon Cancer Patients.

International Journal Of Surgical Oncology

El Agy, Fatima F; El Bardai, Sanae S; Bouguenouch, Laila L; Lahmidani, Nada N; El Abkari, Mohammed M; Benjelloun, El Bachir EB; Ousadden, Abdelmalek A; Mazaz, Khalid K; ImaneToughrai, ; Ibrahimi, Sidi Adil SA; Benbrahim, Zineb Z; Chbani, Laila L

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 35096426

Variant Present in the following documents:

• Main text

View BVdb publication page

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Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer.

Therapeutic Advances In Medical Oncology

Shi, Min M; Yuan, Hong H; Ji, Jun J; Zhang, Shouwei S; Li, Qingyuan Q; Chen, Yawei Y; Gong, Xiaoli X; Zhu, Zhenggang Z; Zhang, Jun J

Publication Date: 2022

Variant appearance in text: rs112445441

PubMed Link: 35096147

Variant Present in the following documents:

• sj-xls-4-tam-10.1177_17588359211070643.xls, sheet 1

View BVdb publication page

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Role of IGF2 in the Study of Development and Evolution of Prostate Cancer.

Frontiers In Genetics

Porras-Quesada, P P; González-Cabezuelo, J M JM; Sánchez-Conde, V V; Puche-Sanz, I I; Arenas-Rodríguez, V V; García-López, C C; Flores-Martín, J F JF; Molina-Hernández, J M JM; Álvarez-Cubero, M J MJ; Martínez-González, L J LJ; Vázquez-Alonso, F F

Publication Date: 2021

Variant appearance in text: rs112445441

PubMed Link: 35095996

Variant Present in the following documents:

• Main text
• fgene-12-740641.pdf

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs112445441

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 6
• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs112445441

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8
• pone.0251286.s005.xlsx, sheet 6

View BVdb publication page

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Phase 1 Clinical Trial of Trametinib and Ponatinib in Patients With NSCLC Harboring KRAS Mutations.

Jto Clinical And Research Reports

Arbour, Kathryn C KC; Manchado, Eusebio E; Bott, Matthew J MJ; Ahn, Linda L; Tobi, Yosef Y; Ni, Andy Ai AA; Yu, Helena A HA; Shannon, Alyssa A; Ladanyi, Marc M; Perron, Victoria V; Ginsberg, Michelle S MS; Johnson, Amanda A; Holodny, Andrei A; Kris, Mark G MG; Rudin, Charles M CM; Lito, Piro P; Rosen, Neal N; Lowe, Scott S; Riely, Gregory J GJ

Publication Date: 2022-01

Variant appearance in text: KRAS: G13V

PubMed Link: 34984405

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.

Computational And Structural Biotechnology Journal

Tripathi, Swarnendu S; Dsouza, Nikita R NR; Mathison, Angela J AJ; Leverence, Elise E; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2022

Variant appearance in text: KRAS: G13V

PubMed Link: 34976316

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.

Blood Cancer Discovery

Fornerod, Maarten M; Ma, Jing J; Noort, Sanne S; Liu, Yu Y; Walsh, Michael P MP; Shi, Lei L; Nance, Stephanie S; Liu, Yanling Y; Wang, Yuanyuan Y; Song, Guangchun G; Lamprecht, Tamara T; Easton, John J; Mulder, Heather L HL; Yergeau, Donald D; Myers, Jacquelyn J; Kamens, Jennifer L JL; Obeng, Esther A EA; Pigazzi, Martina M; Jarosova, Marie M; Kelaidi, Charikleia C; Polychronopoulou, Sophia S; Lamba, Jatinder K JK; Baker, Sharyn D SD; Rubnitz, Jeffrey E JE; Reinhardt, Dirk D; van den Heuvel-Eibrink, Marry M MM; Locatelli, Franco F; Hasle, Henrik H; Klco, Jeffery M JM; Downing, James R JR; Zhang, Jinghui J; Pounds, Stanley S; Zwaan, C Michel CM; Gruber, Tanja A TA; , ; , ; , ; , ; , ; ,

Publication Date: 2021-11

Variant appearance in text: rs112445441

PubMed Link: 34778799

Variant Present in the following documents:

• bloodcandisc-2-586-s001.xlsx, sheet 7

View BVdb publication page

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Evaluation of the MGISEQ-2000 Sequencing Platform for Illumina Target Capture Sequencing Libraries.

Frontiers In Genetics

Lang, Jidong J; Zhu, Rongrong R; Sun, Xue X; Zhu, Siyu S; Li, Tianbao T; Shi, Xiaoli X; Sun, Yanqi Y; Yang, Zhou Z; Wang, Weiwei W; Bing, Pingping P; He, Binsheng B; Tian, Geng G

Publication Date: 2021

Variant appearance in text: KRAS: G13V

PubMed Link: 34777467

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 4

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Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma-Carcinoma Pathway Progression.

Journal Of Inflammation Research

Zhang, Yu Y; Zhang, Xin X; Jin, Zhuoyi Z; Chen, Huiyan H; Zhang, Chenjing C; Wang, Wangyue W; Jing, Jiyong J; Pan, Wensheng W

Publication Date: 2021

Variant appearance in text: rs112445441

PubMed Link: 34737598

Variant Present in the following documents:

• Main text

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The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors.

Nature Communications

Gebregiworgis, Teklab T; Kano, Yoshihito Y; St-Germain, Jonathan J; Radulovich, Nikolina N; Udaskin, Molly L ML; Mentes, Ahmet A; Huang, Richard R; Poon, Betty P K BPK; He, Wenguang W; Valencia-Sama, Ivette I; Robinson, Claire M CM; Huestis, Melissa M; Miao, Jinmin J; Yeh, Jen Jen JJ; Zhang, Zhong-Yin ZY; Irwin, Meredith S MS; Lee, Jeffrey E JE; Tsao, Ming-Sound MS; Raught, Brian B; Marshall, Christopher B CB; Ohh, Michael M; Ikura, Mitsuhiko M

Publication Date: 2021-11-01

Variant appearance in text: KRAS: G13V

PubMed Link: 34725361

Variant Present in the following documents:

• 41467_2021_Article_26526.pdf

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Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers.

Cancers

Dillon, Martha M; Lopez, Antonio A; Lin, Edward E; Sales, Dominic D; Perets, Ron R; Jain, Pooja P

Publication Date: 2021-10-10

Variant appearance in text: KRAS: G13V

PubMed Link: 34680208

Variant Present in the following documents:

• Main text
• cancers-13-05059.pdf

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Interaction between Microsatellite Instability (MSI) and Tumor DNA Methylation in the Pathogenesis of Colorectal Carcinoma.

Cancers

Jasmine, Farzana F; Haq, Zahidul Z; Kamal, Mohammed M; Raza, Maruf M; da Silva, Gustavo G; Gorospe, Katrina K; Paul, Rupash R; Strzempek, Patrick P; Ahsan, Habibul H; Kibriya, Muhammad G MG

Publication Date: 2021-10-01

Variant appearance in text: rs112445441

PubMed Link: 34638440

Variant Present in the following documents:

• Main text
• cancers-13-04956.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KRAS: G13V

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Outcomes and prognostic contributors in patients with KRAS mutated non-small cell pulmonary adenocarcinomas: a single institution experience.

Journal Of Thoracic Disease

Burns, Ethan A EA; Ensor, Joe E JE; Hsu, Jim J; Thomas, Jessica S JS; Olsen, Randall J RJ; Bernicker, Eric H EH

Publication Date: 2021-08

Variant appearance in text: KRAS: G13V

PubMed Link: 34527319

Variant Present in the following documents:

• Main text

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High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.

Thoracic Cancer

Feng, Hui-Bo HB; Chen, Yu Y; Xie, Zhi Z; Jiang, Jie J; Zhong, Yu-Min YM; Guo, Wei-Bang WB; Yan, Wen-Qing WQ; Lv, Zhi-Yi ZY; Lu, Dan-Xia DX; Liang, Hong-Ling HL; Xu, Fang-Ping FP; Yang, Jin-Ji JJ; Yang, Xue-Ning XN; Zhou, Qing Q; Zhang, Dong-Kun DK; Zhang, Zhou Z; Chuai, Shao-Kun SK; Zhang, Heng-Hui HH; Wu, Yi-Long YL; Zhang, Xu-Chao XC

Publication Date: 2021-10

Variant appearance in text: KRAS: G13V

PubMed Link: 34490728

Variant Present in the following documents:

• Main text
• TCA-12-2564.pdf

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High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.

Thoracic Cancer

Feng, Hui-Bo HB; Chen, Yu Y; Xie, Zhi Z; Jiang, Jie J; Zhong, Yu-Min YM; Guo, Wei-Bang WB; Yan, Wen-Qing WQ; Lv, Zhi-Yi ZY; Lu, Dan-Xia DX; Liang, Hong-Ling HL; Xu, Fang-Ping FP; Yang, Jin-Ji JJ; Yang, Xue-Ning XN; Zhou, Qing Q; Zhang, Dong-Kun DK; Zhang, Zhou Z; Chuai, Shao-Kun SK; Zhang, Heng-Hui HH; Wu, Yi-Long YL; Zhang, Xu-Chao XC

Publication Date: 2021-10

Variant appearance in text: KRAS: G13V

PubMed Link: 34490728

Variant Present in the following documents:

• Main text
• TCA-12-2564.pdf

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: KRAS: G13V

PubMed Link: 34440110

Variant Present in the following documents:

• Main text
• biomedicines-09-00906.pdf

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Kras mutation subtypes distinctly affect colorectal cancer cell sensitivity to FL118, a novel inhibitor of survivin, Mcl-1, XIAP, cIAP2 and MdmX.

American Journal Of Translational Research

Thangaiyan, Rabi R; Aljahdali, Ieman Am IA; Lent-Moore, Kelsey Y KY; Liao, Jianqun J; Ling, Xiang X; Li, Fengzhi F

Publication Date: 2021

Variant appearance in text: KRAS: G13V

PubMed Link: 34377229

Variant Present in the following documents:

• Main text

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