Variant ID: 12-25398281-C-T

NM_004985.3(KRAS):c.38G>A;(p.G13D)

This variant was identified in 2152 publications

View GRCh38 version.




Publications:


Cationic copolymers that enhance wild-type-specific suppression in BNA-clamp PCR and preferentially increase the T m of fully matched complementary DNA and BNA strands.

Biology Methods & Protocols
Tachibana, Ami A; Fujimura, Nahohiro N; Takeuchi, Minoru M; Watanabe, Koji K; Teruuchi, Yoko Y; Uchiki, Tomoaki T
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35664806
Variant Present in the following documents:
  • Main text
  • bpac009.pdf
  • bpac009_supplementary_data.pdf
View BVdb publication page



Identification of Synergistic Drug Combinations to Target KRAS-Driven Chemoradioresistant Cancers Utilizing Tumoroid Models of Colorectal Adenocarcinoma and Recurrent Glioblastoma.

Frontiers In Oncology
Gupta, Kshama K; Jones, Jeremy C JC; Farias, Virginea De Araujo VA; Mackeyev, Yuri Y; Singh, Pankaj K PK; Quiñones-Hinojosa, Alfredo A; Krishnan, Sunil S
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35664781
Variant Present in the following documents:
  • Main text
  • fonc-12-840241.pdf
View BVdb publication page



Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer.

Journal Of Experimental & Clinical Cancer Research : Cr
Yang, Lu L; Bhattacharya, Arup A; Li, Yun Y; Sexton, Sandra S; Ling, Xiang X; Li, Fengzhi F; Zhang, Yuesheng Y
Publication Date: 2022-06-02

Variant appearance in text: KRAS: G13D
PubMed Link: 35650607
Variant Present in the following documents:
  • Main text
  • 13046_2022_Article_2389.pdf
View BVdb publication page



Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy.

Acta Pharmaceutica Sinica. B
Pan, Xiaoli X; Pei, Junping J; Wang, Aoxue A; Shuai, Wen W; Feng, Lu L; Bu, Faqian F; Zhu, Yumeng Y; Zhang, Lan L; Wang, Guan G; Ouyang, Liang L
Publication Date: 2022-05

Variant appearance in text: KRAS: G13D
PubMed Link: 35646548
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Molecular Signatures of KRAS-Mutated Lung Adenocarcinoma: Analysis of Concomitant EGFR, ALK, STK11, and PD-L1 Status.

Clinical Pathology (Thousand Oaks, Ventura County, Calif.)
Hsu, Jim J; Annunziata, Joseph F JF; Burns, Ethan E; Bernicker, Eric H EH; Olsen, Randall J RJ; Thomas, Jessica S JS
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35634237
Variant Present in the following documents:
  • Main text
  • 10.1177_2632010X221102054.pdf
View BVdb publication page



Molecular Dynamics Simulations Reveal Structural Interconnections within Sec14-PH Bipartite Domain from Human Neurofibromin.

International Journal Of Molecular Sciences
Rizza, Fabio F; Vertemara, Jacopo J; Tisi, Renata R
Publication Date: 2022-05-20

Variant appearance in text: KRAS: G13D
PubMed Link: 35628517
Variant Present in the following documents:
  • ijms-23-05707.pdf
View BVdb publication page



Basic Science with Preclinical Models to Investigate and Develop Liquid Biopsy: What Are the Available Data and Is It a Fruitful Approach?

International Journal Of Molecular Sciences
Cena, Benedetta B; Melloul, Emmanuel E; Demartines, Nicolas N; Dormond, Olivier O; Labgaa, Ismail I
Publication Date: 2022-05-10

Variant appearance in text: KRAS: G13D
PubMed Link: 35628154
Variant Present in the following documents:
  • ijms-23-05343.pdf
View BVdb publication page



Disentangling ERBB Signaling in Breast Cancer Subtypes-A Model-Based Analysis.

Cancers
Kemmer, Svenja S; Berdiel-Acer, Mireia M; Reinz, Eileen E; Sonntag, Johanna J; Tarade, Nooraldeen N; Bernhardt, Stephan S; Fehling-Kaschek, Mirjam M; Hasmann, Max M; Korf, Ulrike U; Wiemann, Stefan S; Timmer, Jens J
Publication Date: 2022-05-12

Variant appearance in text: KRAS: G13D
PubMed Link: 35625984
Variant Present in the following documents:
  • Main text
  • cancers-14-02379.pdf
View BVdb publication page



Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of β-Catenin Regardless of APC and β-Catenin Mutational Status.

Biomedicines
Garavaglia, Beatrice B; Vallino, Letizia L; Ferraresi, Alessandra A; Esposito, Andrea A; Salwa, Amreen A; Vidoni, Chiara C; Gentilli, Sergio S; Isidoro, Ciro C
Publication Date: 2022-05-13

Variant appearance in text: KRAS: G13D
PubMed Link: 35625868
Variant Present in the following documents:
  • biomedicines-10-01131.pdf
View BVdb publication page



Colorectal Cancer Heterogeneity and the Impact on Precision Medicine and Therapy Efficacy.

Biomedicines
Rosati, Gerardo G; Aprile, Giuseppe G; Colombo, Alfredo A; Cordio, Stefano S; Giampaglia, Marianna M; Cappetta, Alessandro A; Porretto, Concetta Maria CM; De Stefano, Alfonso A; Bilancia, Domenico D; Avallone, Antonio A
Publication Date: 2022-04-30

Variant appearance in text: KRAS: G13D
PubMed Link: 35625772
Variant Present in the following documents:
  • Main text
  • biomedicines-10-01035.pdf
View BVdb publication page



KRAS/NRAS/BRAF Mutation Rate in Saudi Academic Hospital Patients With Colorectal Cancer.

Cureus
Saharti, Samah S
Publication Date: 2022-04

Variant appearance in text: KRAS: G13D
PubMed Link: 35619874
Variant Present in the following documents:
  • Main text
  • cureus-0014-00000024392.pdf
View BVdb publication page



Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells.

Plos One
Manoharan, Ganesh Babu GB; Okutachi, Sunday S; Abankwa, Daniel D
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35617282
Variant Present in the following documents:
  • Main text
  • pone.0268635.pdf
View BVdb publication page



The Current Landscape of mRNA Vaccines Against Viruses and Cancer-A Mini Review.

Frontiers In Immunology
Ladak, Reese Jalal RJ; He, Alexander J AJ; Huang, Yu-Hsun YH; Ding, Yu Y
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35603213
Variant Present in the following documents:
  • Main text
  • fimmu-13-885371.pdf
View BVdb publication page



Comprehensive Evaluation and Application of a Novel Method to Isolate Cell-Free DNA Derived From Bile of Biliary Tract Cancer Patients.

Frontiers In Oncology
Shen, Ningjia N; Zhu, Bin B; Zhang, Wei W; Nian, Baoning B; Xu, Xiaoya X; Yu, Lianghe L; Ruan, Xiang X; Chen, Sheng S; Liu, Yang Y; Cao, Xinkai X; Shi, Xintong X; Li, Zhikuan Z; Huang, Xingfeng X; Wang, Xiang X; Chen, Caifu C; Xiong, Lei L; Zhang, Dadong D; Fu, Xiaohui X; Zhang, Yongjie Y
Publication Date: 2022

Variant appearance in text: KRAS: 38G>A; G13D
PubMed Link: 35600407
Variant Present in the following documents:
  • Main text
  • DataSheet_3.pdf
  • fonc-12-891917.pdf
View BVdb publication page



Free Energy Profiles Relating With Conformational Transition of the Switch Domains Induced by G12 Mutations in GTP-Bound KRAS.

Frontiers In Molecular Biosciences
Chen, Jianzhong J; Zhang, Shaolong S; Zeng, Qingkai Q; Wang, Wei W; Zhang, Qinggang Q; Liu, Xinguo X
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35586192
Variant Present in the following documents:
  • fmolb-09-912518.pdf
View BVdb publication page



Resistance to ERK1/2 pathway inhibitors; sweet spots, fitness deficits and drug addiction.

Cancer Drug Resistance (Alhambra, Calif.)
Sale, Matthew J MJ; Balmanno, Kathryn K; Cook, Simon J SJ
Publication Date: 2019

Variant appearance in text: KRAS: G13D
PubMed Link: 35582726
Variant Present in the following documents:
  • cdr-2-365.pdf
View BVdb publication page



Efficacy of ICIs on patients with oncogene-driven non-small cell lung cancer: a retrospective study.

Cancer Drug Resistance (Alhambra, Calif.)
Guo, Xiaojin X; Du, He H; Li, Jiayu J; Yang, Menghang M; Xiong, Anweng A; Zhang, Haiping H; Wu, Fengying F
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35582532
Variant Present in the following documents:
  • cdr-5-15.pdf
View BVdb publication page



Emerging RAS-directed therapies for cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Conroy, Michael M; Cowzer, Darren D; Kolch, Walter W; Duffy, Austin G AG
Publication Date: 2021

Variant appearance in text: KRAS: G13D
PubMed Link: 35582302
Variant Present in the following documents:
  • cdr-4-543.pdf
View BVdb publication page



A novel nanobody as therapeutics target for EGFR-positive colorectal cancer therapy: exploring the effects of the nanobody on SW480 cells using proteomics approach.

Proteome Science
Lamtha, Thomanai T; Krobthong, Sucheewin S; Yingchutrakul, Yodying Y; Samutrtai, Pawitrabhorn P; Gerner, Christopher C; Tabtimmai, Lueacha L; Choowongkomon, Kiattawee K
Publication Date: 2022-05-16

Variant appearance in text: KRAS: G13D
PubMed Link: 35578244
Variant Present in the following documents:
  • 12953_2022_Article_190.pdf
View BVdb publication page



The paradigm shift in treatment from Covid-19 to oncology with mRNA vaccines.

Cancer Treatment Reviews
Wei, Jiao J; Hui, Ai-Min AM
Publication Date: 2022-05-05

Variant appearance in text: KRAS: G13D
PubMed Link: 35576777
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study.

Oncotarget
Sciortino, Carolina C; Viglialoro, Valentina V; Nucci, Massimo M; Polito, Mariam Grazia MG; Cortesi, Enrico E; Gelibter, Alain A; Gazzaniga, Paola P; Nicolazzo, Chiara C; Siringo, Marco M; Caponnetto, Salvatore S
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35574217
Variant Present in the following documents:
  • oncotarget-13-28230.pdf
View BVdb publication page



Relative Telomere Length Change in Colorectal Carcinoma and Its Association with Tumor Characteristics, Gene Expression and Microsatellite Instability.

Cancers
Kibriya, Muhammad G MG; Raza, Maruf M; Kamal, Mohammed M; Haq, Zahidul Z; Paul, Rupash R; Mareczko, Andrew A; Pierce, Brandon L BL; Ahsan, Habibul H; Jasmine, Farzana F
Publication Date: 2022-04-30

Variant appearance in text: rs112445441
PubMed Link: 35565379
Variant Present in the following documents:
  • cancers-14-02250.pdf
View BVdb publication page



Prognostic and Immunotherapeutic Roles of KRAS in Pan-Cancer.

Cells
Yang, Kaixin K; Li, Chengyun C; Liu, Yang Y; Gu, Xueyan X; Jiang, Longchang L; Shi, Lei L
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G13D
PubMed Link: 35563733
Variant Present in the following documents:
  • cells-11-01427.pdf
View BVdb publication page



Discovery of Raf Family Is a Milestone in Deciphering the Ras-Mediated Intracellular Signaling Pathway.

International Journal Of Molecular Sciences
Zhao, Jingtong J; Luo, Zhijun Z
Publication Date: 2022-05-05

Variant appearance in text: KRAS: G13D
PubMed Link: 35563547
Variant Present in the following documents:
  • ijms-23-05158.pdf
View BVdb publication page



Preparation of Duplex Sequencing Libraries for Archival Paraffin-Embedded Tissue Samples Using Single-Strand-Specific Nuclease P1.

International Journal Of Molecular Sciences
Mitiushkina, Natalia V NV; Yanus, Grigory A GA; Kuligina, Ekatherina Sh ES; Laidus, Tatiana A TA; Romanko, Alexandr A AA; Kholmatov, Maksim M MM; Ivantsov, Alexandr O AO; Aleksakhina, Svetlana N SN; Imyanitov, Evgeny N EN
Publication Date: 2022-04-21

Variant appearance in text: KRAS: G13D
PubMed Link: 35562977
Variant Present in the following documents:
  • ijms-23-04586.pdf
View BVdb publication page



PD-L1 Expression in Non-Small Cell Lung Cancer Specimens: Association with Clinicopathological Factors and Molecular Alterations.

International Journal Of Molecular Sciences
Mansour, Mohammed S I MSI; Malmros, Karina K; Mager, Ulrich U; Ericson Lindquist, Kajsa K; Hejny, Kim K; Holmgren, Benjamin B; Seidal, Tomas T; Dejmek, Annika A; Dobra, Katalin K; Planck, Maria M; Brunnström, Hans H
Publication Date: 2022-04-19

Variant appearance in text: KRAS: G13D
PubMed Link: 35562908
Variant Present in the following documents:
  • ijms-23-04517.pdf
View BVdb publication page



Differential expression analysis of genes and long non-coding RNAs associated with KRAS mutation in colorectal cancer cells.

Scientific Reports
Saliani, Mahsa M; Jalal, Razieh R; Javadmanesh, Ali A
Publication Date: 2022-05-13

Variant appearance in text: KRAS: G13D
PubMed Link: 35562390
Variant Present in the following documents:
  • 41598_2022_Article_11697.pdf
View BVdb publication page



AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

Nature Communications
Kim, Dae Gyu DG; Choi, Yongseok Y; Lee, Yuno Y; Lim, Semi S; Kong, Jiwon J; Song, JaeHa J; Roh, Younah Y; Harmalkar, Dipesh S DS; Lee, Kwanshik K; Goo, Ja-Il JI; Cho, Hye Young HY; Mushtaq, Ameeq Ul AU; Lee, Jihye J; Park, Song Hwa SH; Kim, Doyeun D; Min, Byung Soh BS; Lee, Kang Young KY; Jeon, Young Ho YH; Lee, Sunkyung S; Lee, Kyeong K; Kim, Sunghoon S
Publication Date: 2022-05-11

Variant appearance in text: KRAS: G13D
PubMed Link: 35546148
Variant Present in the following documents:
  • 41467_2022_30149_MOESM1_ESM.pdf
View BVdb publication page



Fundamental immune-oncogenicity trade-offs define driver mutation fitness.

Nature
Hoyos, David D; Zappasodi, Roberta R; Schulze, Isabell I; Sethna, Zachary Z; de Andrade, Kelvin César KC; Bajorin, Dean F DF; Bandlamundi, Chaitanya C; Callahan, Margaret K MK; Funt, Samuel A SA; Hadrup, Sine R SR; Holm, Jeppe S JS; Rosenberg, Jonathan E JE; Shah, Sohrab P SP; Vázquez-García, Ignacio I; Weigelt, Britta B; Wu, Michelle M; Zamarin, Dmitriy D; Campitelli, Laura F LF; Osborne, Edward J EJ; Klinger, Mark M; Robins, Harlan S HS; Khincha, Payal P PP; Savage, Sharon A SA; Balachandran, Vinod P VP; Wolchok, Jedd D JD; Hellmann, Matthew D MD; Merghoub, Taha T; Levine, Arnold J AJ; Łuksza, Marta M; Greenbaum, Benjamin D BD
Publication Date: 2022-05-11

Variant appearance in text: KRAS: G13D
PubMed Link: 35545680
Variant Present in the following documents:
  • Main text
  • 41586_2022_4696_MOESM3_ESM.pdf
  • 41586_2022_Article_4696.pdf
View BVdb publication page



Comprehensive Molecular Profiling of Colorectal Cancer With Situs Inversus Totalis by Next-Generation Sequencing.

Frontiers In Oncology
Li, Hongsen H; Gong, Liu L; Cheng, Huanqing H; Wang, Huina H; Zhang, Xiaochen X; Rao, Chuangzhou C; Song, Zhangfa Z; Wang, Da D; Lou, Haizhou H; Lou, Feng F; Cao, Shanbo S; Pan, Hongming H; Fang, Yong Y
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35530355
Variant Present in the following documents:
  • fonc-12-813253.pdf
View BVdb publication page



Targeting Mutant Kirsten Rat Sarcoma Viral Oncogene Homolog in Non-Small Cell Lung Cancer: Current Difficulties, Integrative Treatments and Future Perspectives.

Frontiers In Pharmacology
Li, Jia-Xin JX; Li, Run-Ze RZ; Ma, Lin-Rui LR; Wang, Peng P; Xu, Dong-Han DH; Huang, Jie J; Li, Li-Qi LQ; Tang, Ling L; Xie, Ying Y; Leung, Elaine Lai-Han EL; Yan, Pei-Yu PY
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35517800
Variant Present in the following documents:
  • fphar-13-875330.pdf
View BVdb publication page



Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer
Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E
Publication Date: 2022-05-03

Variant appearance in text: rs112445441
PubMed Link: 35505283
Variant Present in the following documents:
  • 12885_2022_9619_MOESM1_ESM.xlsx
View BVdb publication page



A centrifugation-assisted visual detection of SNP in circulating tumor DNA using gold nanoparticles coupled with isothermal amplification.

Rsc Advances
Wang, Yusong Y; Kong, Say Li SL; Su, Xiao Di XD
Publication Date: 2020-01-07

Variant appearance in text: KRAS: G13D
PubMed Link: 35494678
Variant Present in the following documents:
  • RA-010-C9RA09029K.pdf
View BVdb publication page



Multi-targeting of K-Ras domains and mutations by peptide and small molecule inhibitors.

Plos Computational Biology
Poorebrahim, Mansour M; Abazari, Mohammad Foad MF; Moradi, Leila L; Shahbazi, Behzad B; Mahmoudi, Reza R; Kalhor, Hourieh H; Askari, Hassan H; Teimoori-Toolabi, Ladan L
Publication Date: 2022-04

Variant appearance in text: K-Ras4B: G13D
PubMed Link: 35472201
Variant Present in the following documents:
  • pcbi.1009962.pdf
View BVdb publication page



A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRASG12C inhibitors.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Feng, Siyu S; Callow, Marinella G MG; Fortin, Jean-Philippe JP; Khan, Zia Z; Bray, David D; Costa, Mike M; Shi, Zhen Z; Wang, Weiru W; Evangelista, Marie M
Publication Date: 2022-05-03

Variant appearance in text: KRAS: G13D
PubMed Link: 35471904
Variant Present in the following documents:
  • pnas.202120512.pdf
View BVdb publication page



Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics
Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R
Publication Date: 2022-04-25

Variant appearance in text: KRAS: G13D
PubMed Link: 35468810
Variant Present in the following documents:
  • 12920_2022_1235_MOESM3_ESM.xlsx
  • 12920_2022_1235_MOESM2_ESM.xlsx
View BVdb publication page



Autopromotion of K-Ras4B Feedback Activation Through an SOS-Mediated Long-Range Allosteric Effect.

Frontiers In Molecular Biosciences
He, Xuan X; Du, Kui K; Wang, Yuanhao Y; Fan, Jigang J; Li, Mingyu M; Ni, Duan D; Lu, Shaoyong S; Bian, Xiaolan X; Liu, Yaqin Y
Publication Date: 2022

Variant appearance in text: K-Ras4B: G13D
PubMed Link: 35463958
Variant Present in the following documents:
  • fmolb-09-860962.pdf
View BVdb publication page



Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients.

Iranian Journal Of Pathology
Mirzapour Abbas Abadi, Zohreh Z; Samiee Rad, Fatemeh F; Hamedi Asl, Dariush D; Rahmani, Babak B; Soleimani Dodaran, Mahmood M; Peimani, Amir A
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35463728
Variant Present in the following documents:
  • ijp-17-150.pdf
View BVdb publication page



Preclinical Models for Acquired Resistance to Third-Generation EGFR Inhibitors in NSCLC: Functional Studies and Drug Combinations Used to Overcome Resistance.

Frontiers In Oncology
Mahfoudhi, Emna E; Ricordel, Charles C; Lecuyer, Gwendoline G; Mouric, Cécile C; Lena, Hervé H; Pedeux, Rémy R
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35463360
Variant Present in the following documents:
  • fonc-12-853501.pdf
View BVdb publication page



Concurrent RAS and RAS/BRAF V600E Variants in Colorectal Cancer: More Frequent Than Expected? A Case Report.

Frontiers In Oncology
Zelli, Veronica V; Parisi, Alessandro A; Patruno, Leonardo L; Cannita, Katia K; Ficorella, Corrado C; Luzi, Carla C; Compagnoni, Chiara C; Zazzeroni, Francesca F; Alesse, Edoardo E; Tessitore, Alessandra A
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35463316
Variant Present in the following documents:
  • fonc-12-863639.pdf
View BVdb publication page



Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.

American Journal Of Human Genetics
Palles, Claire C; West, Hannah D HD; Chew, Edward E; Galavotti, Sara S; Flensburg, Christoffer C; Grolleman, Judith E JE; Jansen, Erik A M EAM; Curley, Helen H; Chegwidden, Laura L; Arbe-Barnes, Edward H EH; Lander, Nicola N; Truscott, Rebekah R; Pagan, Judith J; Bajel, Ashish A; Sherwood, Kitty K; Martin, Lynn L; Thomas, Huw H; Georgiou, Demetra D; Fostira, Florentia F; Goldberg, Yael Y; Adams, David J DJ; van der Biezen, Simone A M SAM; Christie, Michael M; Clendenning, Mark M; Thomas, Laura E LE; Deltas, Constantinos C; Dimovski, Aleksandar J AJ; Dymerska, Dagmara D; Lubinski, Jan J; Mahmood, Khalid K; van der Post, Rachel S RS; Sanders, Mathijs M; Weitz, Jürgen J; Taylor, Jenny C JC; Turnbull, Clare C; Vreede, Lilian L; van Wezel, Tom T; Whalley, Celina C; Arnedo-Pac, Claudia C; Caravagna, Giulio G; Cross, William W; Chubb, Daniel D; Frangou, Anna A; Gruber, Andreas J AJ; Kinnersley, Ben B; Noyvert, Boris B; Church, David D; Graham, Trevor T; Houlston, Richard R; Lopez-Bigas, Nuria N; Sottoriva, Andrea A; Wedge, David D; , ; , ; , ; Jenkins, Mark A MA; Kuiper, Roland P RP; Roberts, Andrew W AW; Cheadle, Jeremy P JP; Ligtenberg, Marjolijn J L MJL; Hoogerbrugge, Nicoline N; Koelzer, Viktor H VH; Rivas, Andres Dacal AD; Winship, Ingrid M IM; Ponte, Clara Ruiz CR; Buchanan, Daniel D DD; Power, Derek G DG; Green, Andrew A; Tomlinson, Ian P M IPM; Sampson, Julian R JR; Majewski, Ian J IJ; de Voer, Richarda M RM
Publication Date: 2022-04-20

Variant appearance in text: KRAS: 38G>A; Gly13Asp
PubMed Link: 35460607
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



KRAS: A Druggable Target in Colon Cancer Patients.

International Journal Of Molecular Sciences
Negri, Francesca F; Bottarelli, Lorena L; de'Angelis, Gian Luigi GL; Gnetti, Letizia L
Publication Date: 2022-04-08

Variant appearance in text: KRAS: G13D
PubMed Link: 35456940
Variant Present in the following documents:
  • ijms-23-04120.pdf
View BVdb publication page



Colorectal Cancer Diagnosis: The Obstacles We Face in Determining a Non-Invasive Test and Current Advances in Biomarker Detection.

Cancers
Kamel, Faddy F; Eltarhoni, Khadiga K; Nisar, Pasha P; Soloviev, Mikhail M
Publication Date: 2022-04-08

Variant appearance in text: KRAS: G13D
PubMed Link: 35454792
Variant Present in the following documents:
  • cancers-14-01889.pdf
View BVdb publication page



Longitudinal Study of Circulating Biomarkers in Patients with Resectable Pancreatic Ductal Adenocarcinoma.

Biosensors
Dopico, Pablo J PJ; Le, Minh-Chau N MN; Burgess, Benjamin B; Yang, Zhijie Z; Zhao, Yu Y; Wang, Youxiang Y; George, Thomas J TJ; Fan, Z Hugh ZH
Publication Date: 2022-03-30

Variant appearance in text: KRAS: G13D
PubMed Link: 35448266
Variant Present in the following documents:
  • biosensors-12-00206.pdf
View BVdb publication page



Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use.

Plos One
Shi, Zonggao Z; Lopez, Jacqueline J; Kalliney, William W; Sutton, Bobbie B; Simpson, Joyce J; Maggert, Kevin K; Liu, Sheng S; Wan, Jun J; Stack, M Sharon MS
Publication Date: 2022

Variant appearance in text: KRAS: 38G>A; G13D
PubMed Link: 35446881
Variant Present in the following documents:
  • pone.0266914.pdf
View BVdb publication page



Synergistic combination of PMBA and 5-fluorouracil (5-FU) in targeting mutant KRAS in 2D and 3D colorectal cancer cells.

Heliyon
Qayum, Arem A; Magotra, Asmita A; Shah, Syed Mohmad SM; Nandi, Utpal U; Sharma, P R PR; Shah, Bhahwal Ali BA; Singh, Shashank Kumar SK
Publication Date: 2022-04

Variant appearance in text: KRAS: G13D
PubMed Link: 35445157
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Simultaneous monitoring of disease and microbe dynamics through plasma DNA sequencing in pediatric patients with acute lymphoblastic leukemia.

Science Advances
Barsan, Valentin V; Xia, Yuntao Y; Klein, David D; Gonzalez-Pena, Veronica V; Youssef, Sarah S; Inaba, Yuki Y; Mahmud, Ousman O; Natarajan, Sivaraman S; Agarwal, Vibhu V; Pang, Yakun Y; Autry, Robert R; Pui, Ching-Hon CH; Inaba, Hiroto H; Evans, William W; Gawad, Charles C
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G13D
PubMed Link: 35442732
Variant Present in the following documents:
  • sciadv.abj1360.pdf
View BVdb publication page



An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse.

Bmc Genomic Data
Bartsch, Lorenz L; Schroeder, Michael P MP; Hänzelmann, Sonja S; Bastian, Lorenz L; Lázaro-Navarro, Juan J; Schlee, Cornelia C; Tanchez, Jutta Ortiz JO; Schulze, Veronika V; Isaakidis, Konstandina K; Rieger, Michael A MA; Gökbuget, Nicola N; Eckert, Cornelia C; Serve, Hubert H; Horstmann, Martin M; Schrappe, Martin M; Brüggemann, Monika M; Baldus, Claudia D CD; Neumann, Martin M
Publication Date: 2022-04-18

Variant appearance in text: KRAS: G13D; rs112445441
PubMed Link: 35436854
Variant Present in the following documents:
  • 12863_2022_1041_MOESM15_ESM.xlsx
View BVdb publication page



De Novo KRAS G12C-Mutant SCLC: A Case Report.

Jto Clinical And Research Reports
Balbach, Meridith L ML; Eisenberg, Rosana R; Iams, Wade T WT
Publication Date: 2022-05

Variant appearance in text: KRAS: G13D
PubMed Link: 35434667
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



The Role of Anti-EGFR Monoclonal Antibody in mCRC Maintenance Therapy.

Frontiers In Molecular Biosciences
Yuan, Meiqin M; Wang, Zeng Z; Lv, Wangxia W; Pan, Hongming H
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35433839
Variant Present in the following documents:
  • fmolb-09-870395.pdf
View BVdb publication page



The Potential Role of Genomic Signature in Stage II Relapsed Colorectal Cancer (CRC) Patients: A Mono-Institutional Study.

Cancer Management And Research
Roberto, Michela M; Arrivi, Giulia G; Pilozzi, Emanuela E; Montori, Andrea A; Balducci, Genoveffa G; Mercantini, Paolo P; Laghi, Andrea A; Ierinò, Debora D; Panebianco, Martina M; Marinelli, Daniele D; Tomao, Silverio S; Marchetti, Paolo P; Mazzuca, Federica F
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35418781
Variant Present in the following documents:
  • cmar-14-1353.pdf
View BVdb publication page



Lineage Conversion in Pediatric B-Cell Precursor Acute Leukemia under Blinatumomab Therapy.

International Journal Of Molecular Sciences
Semchenkova, Alexandra A; Mikhailova, Ekaterina E; Komkov, Alexander A; Gaskova, Marina M; Abasov, Ruslan R; Matveev, Evgenii E; Kazanov, Marat M; Mamedov, Ilgar I; Shmitko, Anna A; Belova, Vera V; Miroshnichenkova, Anna A; Illarionova, Olga O; Olshanskaya, Yulia Y; Tsaur, Grigory G; Verzhbitskaya, Tatiana T; Ponomareva, Natalia N; Bronin, Gleb G; Kondratchik, Konstantin K; Fechina, Larisa L; Diakonova, Yulia Y; Vavilova, Liudmila L; Myakova, Natalia N; Novichkova, Galina G; Maschan, Alexey A; Maschan, Michael M; Zerkalenkova, Elena E; Popov, Alexander A
Publication Date: 2022-04-05

Variant appearance in text: KRAS: G13D
PubMed Link: 35409391
Variant Present in the following documents:
  • ijms-23-04019.pdf
View BVdb publication page



Overcoming Steroid Resistance in Pediatric Acute Lymphoblastic Leukemia-The State-of-the-Art Knowledge and Future Prospects.

International Journal Of Molecular Sciences
Kośmider, Kamil K; Karska, Katarzyna K; Kozakiewicz, Agata A; Lejman, Monika M; Zawitkowska, Joanna J
Publication Date: 2022-03-30

Variant appearance in text: KRAS: G13D
PubMed Link: 35409154
Variant Present in the following documents:
  • ijms-23-03795.pdf
View BVdb publication page



A Liquid Biopsy-Based Approach for Monitoring Treatment Response in Post-Operative Colorectal Cancer Patients.

International Journal Of Molecular Sciences
Barták, Barbara Kinga BK; Fodor, Tamás T; Kalmár, Alexandra A; Nagy, Zsófia Brigitta ZB; Zsigrai, Sára S; Szigeti, Krisztina Andrea KA; Valcz, Gábor G; Igaz, Péter P; Dank, Magdolna M; Takács, István I; Molnár, Béla B
Publication Date: 2022-03-29

Variant appearance in text: KRAS: G13D
PubMed Link: 35409133
Variant Present in the following documents:
  • ijms-23-03774.pdf
View BVdb publication page



Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies.

International Journal Of Molecular Sciences
Shetu, Shaila A SA; Bandyopadhyay, Debasish D
Publication Date: 2022-03-28

Variant appearance in text: KRAS: G13D
PubMed Link: 35409064
Variant Present in the following documents:
  • ijms-23-03706.pdf
View BVdb publication page



Daily Practice Assessment of KRAS Status in NSCLC Patients: A New Challenge for the Thoracic Pathologist Is Right around the Corner.

Cancers
Bontoux, Christophe C; Hofman, Véronique V; Brest, Patrick P; Ilié, Marius M; Mograbi, Baharia B; Hofman, Paul P
Publication Date: 2022-03-23

Variant appearance in text: KRAS: G13D
PubMed Link: 35406400
Variant Present in the following documents:
  • cancers-14-01628.pdf
View BVdb publication page



Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis.

Frontiers In Oncology
Kyrochristos, Ioannis D ID; Glantzounis, Georgios K GK; Goussia, Anna A; Eliades, Alexia A; Achilleos, Achilleas A; Tsangaras, Kyriakos K; Hadjidemetriou, Irene I; Elpidorou, Marilena M; Ioannides, Marios M; Koumbaris, George G; Mitsis, Michail M; Patsalis, Philippos C PC; Roukos, Dimitrios D
Publication Date: 2022

Variant appearance in text: KRAS: 38G>A
PubMed Link: 35402285
Variant Present in the following documents:
  • Table_1.xlsx
View BVdb publication page



Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA.

Frontiers In Oncology
Lee, Jong Won JW; Park, Young Soo YS; Choi, Jung Yoon JY; Chang, Won Jin WJ; Lee, Soohyeon S; Sung, Jae Sook JS; Kim, Boyeon B; Lee, Saet Byeol SB; Lee, Sung Yong SY; Choi, Jungmin J; Kim, Yeul Hong YH
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35402275
Variant Present in the following documents:
  • fonc-12-843561.pdf
View BVdb publication page



Adjuvant therapy for periampullary carcinoma and the significance of histopathological typing: A systematic review.

Translational Oncology
Duan, Zhiqing Z; Zhang, Yinuo Y; Tang, Yajie Y; Gao, Ruqing R; Bao, Jing J; Liang, Bo B
Publication Date: 2022-04-06

Variant appearance in text: KRAS: G13D
PubMed Link: 35397420
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Comprehensive analysis of genetic factors predicting overall survival in Myelodysplastic syndromes.

Scientific Reports
Maurya, Nehakumari N; Mohanty, Purvi P; Dhangar, Somprakash S; Panchal, Purvi P; Jijina, Farah F; Mathan, S Leo Prince SLP; Shanmukhaiah, Chandrakala C; Madkaikar, Manisha M; Vundinti, Babu Rao BR
Publication Date: 2022-04-08

Variant appearance in text: KRAS: 38G>A; Gly13Asp
PubMed Link: 35396491
Variant Present in the following documents:
  • 41598_2022_9864_MOESM9_ESM.xlsx
View BVdb publication page



Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing.

Scientific Reports
Tjensvoll, Kjersti K; Lapin, Morten M; Gilje, Bjørnar B; Garresori, Herish H; Oltedal, Satu S; Forthun, Rakel Brendsdal RB; Molven, Anders A; Rozenholc, Yves Y; Nordgård, Oddmund O
Publication Date: 2022-04-06

Variant appearance in text: KRAS: G13D
PubMed Link: 35388068
Variant Present in the following documents:
  • 41598_2022_Article_9698.pdf
View BVdb publication page



Therapeutic impact and routine application of next-generation sequencing: A single institute study.

Biomedical Reports
Hernández-Pacheco Acosta, Rocío R; Del Carmen Damas Fuentes, María M; Gallego Pena, Nicolás N; Soto Rojas, Pilar P; Beato Zambrano, Carmen C
Publication Date: 2022-05

Variant appearance in text: KRAS: G13D
PubMed Link: 35386110
Variant Present in the following documents:
  • br-16-05-01516.pdf
View BVdb publication page



Genomic clonal evolution correlated with phenotype and prognosis in gastric cancer.

Clinical And Translational Medicine
Ge, Jie J; Li, Xuan X; Deng, Zhenghao Z; Gao, Xuan X; Liu, Yaoyao Y; Xiong, Xingui X; Zhao, Xianhui X; Peng, Huan H; Yi, Xin X; Xia, Xuefeng X; Chen, Zihua Z; Li, Lifeng L; Zhou, Haiyan H; Liu, Heli H
Publication Date: 2022-04

Variant appearance in text: KRAS: 38G>A; G13D
PubMed Link: 35384329
Variant Present in the following documents:
  • CTM2-12-e799-s006.xlsx
View BVdb publication page



Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells.

Bmc Cancer
Chauvin, Anaïs A; Bergeron, Danny D; Vencic, Jean J; Lévesque, Dominique D; Paquette, Benoit B; Scott, Michelle S MS; Boisvert, François-Michel FM
Publication Date: 2022-04-04

Variant appearance in text: KRAS: G13D
PubMed Link: 35379199
Variant Present in the following documents:
  • 12885_2022_Article_9417.pdf
View BVdb publication page



KRAS Mutation in Rare Tumors: A Landscape Analysis of 3453 Chinese Patients.

Frontiers In Molecular Biosciences
Wang, Shuhang S; Li, Qin Q; Ma, Peiwen P; Fang, Yuan Y; Yu, Yue Y; Jiang, Ning N; Miao, Huilei H; Tang, Qiyu Q; Yang, Yuqi Y; Xing, Shujun S; Chen, Rongrong R; Yi, Xin X; Li, Ning N
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35359599
Variant Present in the following documents:
  • fmolb-09-831382.pdf
View BVdb publication page



The Influence of Oncogenic RAS on Chemotherapy and Radiotherapy Resistance Through DNA Repair Pathways.

Frontiers In Cell And Developmental Biology
Cáceres-Gutiérrez, Rodrigo E RE; Alfaro-Mora, Yair Y; Andonegui, Marco A MA; Díaz-Chávez, José J; Herrera, Luis A LA
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35359456
Variant Present in the following documents:
  • fcell-10-751367.pdf
View BVdb publication page



HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.

Frontiers In Pharmacology
Shi, Bin B; Xu, Fang-Fang FF; Xiang, Cai-Ping CP; Li, Chuan-Yan CY; Fan, Ping P; Wang, Hao H
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35355718
Variant Present in the following documents:
  • fphar-13-851401.pdf
View BVdb publication page



Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Nature Communications
Liu, Ting T; Rao, Jianan J; Hu, Wenting W; Cui, Bowen B; Cai, Jiaoyang J; Liu, Yuhan Y; Sun, Huiying H; Chen, Xiaoxiao X; Tang, Yanjing Y; Chen, Jing J; Wang, Xiang X; Wang, Han H; Qian, Wubin W; Mao, Binchen B; Guo, Sheng S; Wang, Ronghua R; Liu, Yu Y; Shen, Shuhong S
Publication Date: 2022-03-28

Variant appearance in text: KRAS: G13D
PubMed Link: 35347147
Variant Present in the following documents:
  • 41467_2022_Article_29336.pdf
  • 41467_2022_29336_MOESM7_ESM.xlsx
View BVdb publication page



Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies.

Frontiers In Cell And Developmental Biology
Park, Kevin K; Veena, Mysore S MS; Shin, Daniel Sanghoon DS
Publication Date: 2022

Variant appearance in text: KRAS: G13D
PubMed Link: 35345849
Variant Present in the following documents:
  • fcell-10-830208.pdf
View BVdb publication page



[Targeted Therapy and Mechanism of Drug Resistance in Non-small Cell Lung Cancer 
with Epidermal Growth Factor Receptor Gene Mutation].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Huang, Junxia J; Wang, Hong H
Publication Date: 2022-03-20

Variant appearance in text: KRAS: G13D
PubMed Link: 35340161
Variant Present in the following documents:
  • zgfazz-25-3-183.pdf
View BVdb publication page



Circulating Tumor DNA Profiling of a Diffuse Large B Cell Lymphoma Patient with Secondary Acute Myeloid Leukemia.

Cancers
Kerle, Irina A IA; Jägerhuber, Ludwig L; Secci, Ramona R; Pfarr, Nicole N; Blüm, Philipp P; Roesch, Romina R; Götze, Katharina S KS; Weichert, Wilko W; Bassermann, Florian F; Ruland, Jürgen J; Winter, Christof C
Publication Date: 2022-03-08

Variant appearance in text: KRAS: G13D
PubMed Link: 35326522
Variant Present in the following documents:
  • cancers-14-01371.pdf
View BVdb publication page



Reverse Electrochemical Sensing of FLT3-ITD Mutations in Acute Myeloid Leukemia Using Gold Sputtered ZnO-Nanorod Configured DNA Biosensors.

Biosensors
Thevendran, Ramesh R; Foo, Kai Loong KL; Hussin, Mohd Hazwan MH; Moses, Emmanuel Jairaj EJ; Citartan, Marimuthu M; Prasad, Haarindraprasad Rajintra HR; Maheswaran, Solayappan S
Publication Date: 2022-03-10

Variant appearance in text: KRAS: G13D
PubMed Link: 35323440
Variant Present in the following documents:
  • biosensors-12-00170.pdf
View BVdb publication page



Landscape of KRASG12C, Associated Genomic Alterations, and Interrelation With Immuno-Oncology Biomarkers in KRAS-Mutated Cancers.

Jco Precision Oncology
Salem, Mohamed E ME; El-Refai, Sherif M SM; Sha, Wei W; Puccini, Alberto A; Grothey, Axel A; George, Thomas J TJ; Hwang, Jimmy J JJ; O'Neil, Bert B; Barrett, Alexander S AS; Kadakia, Kunal C KC; Musselwhite, Laura W LW; Raghavan, Derek D; Van Cutsem, Eric E; Tabernero, Josep J; Tie, Jeanne J
Publication Date: 2022-03

Variant appearance in text: KRAS: G13D
PubMed Link: 35319967
Variant Present in the following documents:
  • po-6-e2100245.pdf
View BVdb publication page



KRAS is vulnerable to reversible switch-II pocket engagement in cells.

Nature Chemical Biology
Vasta, James D JD; Peacock, D Matthew DM; Zheng, Qinheng Q; Walker, Joel A JA; Zhang, Ziyang Z; Zimprich, Chad A CA; Thomas, Morgan R MR; Beck, Michael T MT; Binkowski, Brock F BF; Corona, Cesear R CR; Robers, Matthew B MB; Shokat, Kevan M KM
Publication Date: 2022-03-21

Variant appearance in text: KRAS: G13D
PubMed Link: 35314814
Variant Present in the following documents:
  • Main text
  • 41589_2022_985_MOESM3_ESM.xlsx
  • 41589_2022_985_MOESM1_ESM.pdf
View BVdb publication page