Publications:

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RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.

The Journal Of Clinical Investigation

Ren, Jian-Gang JG; Xing, Bowen B; Lv, Kaosheng K; O'Keefe, Rachel A RA; Wu, Mengfang M; Wang, Ruoxing R; Bauer, Kaylyn M KM; Ghazaryan, Arevik A; Burslem, George M GM; Zhang, Jing J; O'Connell, Ryan M RM; Pillai, Vinodh V; Hexner, Elizabeth O EO; Philips, Mark R MR; Tong, Wei W

Publication Date: 2023-06-15

Variant appearance in text: KRAS: 38G>A; G13D

PubMed Link: 37317963

Variant Present in the following documents:

• jci-133-165510-s058.xlsx, sheet 1

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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm

Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y

Publication Date: 2023-06

Variant appearance in text: KRAS: G13D

PubMed Link: 37250144

Variant Present in the following documents:

• Main text
• MCO2-4-e285.pdf

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Recent Advancements, Limitations, and Future Perspectives of the use of Personalized Medicine in Treatment of Colon Cancer.

Technology In Cancer Research & Treatment

Dey, Amit A; Mitra, Abhijit A; Pathak, Surajit S; Prasad, Suhanya S; Zhang, Alexander Sun AS; Zhang, Hong H; Sun, Xiao-Feng XF; Banerjee, Antara A

Publication Date: 2023

Variant appearance in text: KRAS: G13D

PubMed Link: 37248615

Variant Present in the following documents:

• Main text
• 10.1177_15330338231178403.pdf

View BVdb publication page

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POLE-Mutant Colon Cancer Treated with PD-1 Blockade Showing Clearance of Circulating Tumor DNA and Prolonged Disease-Free Interval.

Genes

Bikhchandani, Mihir M; Amersi, Farin F; Hendifar, Andrew A; Gangi, Alexandra A; Osipov, Arsen A; Zaghiyan, Karen K; Atkins, Katelyn K; Cho, May M; Aguirre, Francesca F; Hazelett, Dennis D; Alvarez, Rocio R; Zhou, Lisa L; Hitchins, Megan M; Gong, Jun J

Publication Date: 2023-05-08

Variant appearance in text: KRAS: G13D

PubMed Link: 37239414

Variant Present in the following documents:

• Main text
• genes-14-01054.pdf

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Clinicopathological Characteristics and Mutational Landscape of APC, HOXB13, and KRAS among Rwandan Patients with Colorectal Cancer.

Current Issues In Molecular Biology

Manirakiza, Felix F; Rutaganda, Eric E; Yamada, Hidetaka H; Iwashita, Yuji Y; Rugwizangoga, Belson B; Seminega, Benoit B; Dusabejambo, Vincent V; Ntakirutimana, Gervais G; Ruhangaza, Deogratias D; Uwineza, Annette A; Shinmura, Kazuya K; Sugimura, Haruhiko H

Publication Date: 2023-05-16

Variant appearance in text: KRAS: Gly13Asp

PubMed Link: 37232746

Variant Present in the following documents:

• Main text
• cimb-45-00277.pdf

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Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS.

Signal Transduction And Targeted Therapy

Yin, Guowei G; Huang, Jing J; Petela, Johnny J; Jiang, Hongmei H; Zhang, Yuetong Y; Gong, Siqi S; Wu, Jiaxin J; Liu, Bei B; Shi, Jianyou J; Gao, Yijun Y

Publication Date: 2023-05-23

Variant appearance in text: KRAS: G13D

PubMed Link: 37221195

Variant Present in the following documents:

• Main text
• 41392_2023_Article_1441.pdf

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The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.

Molecular Cancer

Entrialgo-Cadierno, Rodrigo R; Cueto-Ureña, Cristina C; Welch, Connor C; Feliu, Iker I; Macaya, Irati I; Vera, Laura L; Morales, Xabier X; Michelina, Sandra Vietti SV; Scaparone, Pietro P; Lopez, Ines I; Darbo, Elodie E; Erice, Oihane O; Vallejo, Adrian A; Moreno, Haritz H; Goñi-Salaverri, Ainhoa A; Lara-Astiaso, David D; Halberg, Nils N; Cortes-Dominguez, Ivan I; Guruceaga, Elizabeth E; Ambrogio, Chiara C; Lecanda, Fernando F; Vicent, Silve S

Publication Date: 2023-05-20

Variant appearance in text: KRAS: G13D

PubMed Link: 37210549

Variant Present in the following documents:

• Main text
• 12943_2023_Article_1788.pdf

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Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology

Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2023-04-28

Variant appearance in text: KRAS: G13D

PubMed Link: 37207265

Variant Present in the following documents:

• Main text
• nihpp-2023.04.28.536249v1.pdf
• media-1.pdf

View BVdb publication page

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The efficacy of immune checkpoint inhibitors in biliary tract cancer with KRAS mutation.

Therapeutic Advances In Gastroenterology

Jeong, Sun Young SY; Hong, Jung Yong JY; Park, Joon Oh JO; Park, Young Suk YS; Lim, Ho Yeong HY; Jang, Jae Yeon JY; Jeon, Youngkyung Y; Kim, Seung Tae ST

Publication Date: 2023

Variant appearance in text: KRAS: G13D

PubMed Link: 37163165

Variant Present in the following documents:

• Main text
• 10.1177_17562848231170484.pdf

View BVdb publication page

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Cutaneous Limb Metastasis of Colorectal Cancer Misdiagnosed as Zoster Infection.

Cureus

Albandak, Maram M; Albandak, Miral M; Abdallah, Jasmin J; Qawasmeh, Mohammed M

Publication Date: 2023-03

Variant appearance in text: KRAS: G13D

PubMed Link: 37155449

Variant Present in the following documents:

• cureus-0015-00000036621.pdf

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KRAS mutation: The booster of pancreatic ductal adenocarcinoma transformation and progression.

Frontiers In Cell And Developmental Biology

Zhang, Zining Z; Zhang, Heng H; Liao, Xiang X; Tsai, Hsiang-I HI

Publication Date: 2023

Variant appearance in text: KRAS: G13D

PubMed Link: 37152291

Variant Present in the following documents:

• Main text
• fcell-11-1147676.pdf

View BVdb publication page

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Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia.

The Journal Of Clinical Investigation

Wang, Hua H; Moniruzzaman, Rohan R; Li, Lei L; Ji, Baoan B; Liu, Yi Y; Zuo, Xiangsheng X; Abbasgholizadeh, Reza R; Zhao, Jun J; Liu, Guangchao G; Wang, Ruiqi R; Tang, Hongli H; Sun, Ryan R; Su, Xiaoping X; Tan, Tse-Hua TH; Maitra, Anirban A; Wang, Huamin H

Publication Date: 2023-05-04

Variant appearance in text: KRAS: G13D

PubMed Link: 37140994

Variant Present in the following documents:

• jci-133-163873.pdf

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Genomic profiles of Indonesian colorectal cancer patients.

F1000Research

Abdullah, Murdani M; Meilany, Sofy S; Trimarsanto, Hidayat H; Malik, Safarina G SG; Sukartini, Ninik N; Idrus, Firhat F; Nursyirwan, Saskia A SA; Muzellina, Virly N VN; Pribadi, Rabbinu R RR; Utari, Amanda P AP; Maulahela, Hasan H; Syam, Ari F AF

Publication Date: 2022

Variant appearance in text: KRAS: G13D

PubMed Link: 37125020

Variant Present in the following documents:

• Main text
• f1000research-11-144370.pdf

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KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement.

Acs Bio & Med Chem Au

Pagba, Cynthia V CV; Gupta, Amit K AK; Naji, Ali K AK; van der Hoeven, Dharini D; Churion, Kelly K; Liang, Xiaowen X; Jakubec, Jacob J; Hook, Magnus M; Zuo, Yan Y; Martinez de Kraatz, Marisela M; Frost, Jeffrey A JA; Gorfe, Alemayehu A AA

Publication Date: 2022-12-21

Variant appearance in text: KRAS: G13D

PubMed Link: 37101428

Variant Present in the following documents:

• Main text
• bg2c00045.pdf
• bg2c00045_si_001.pdf

View BVdb publication page

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Combining the amplification refractory mutation system and high-resolution melting analysis for KRAS mutation detection in clinical samples.

Analytical And Bioanalytical Chemistry

Oliveira, Beatriz B BB; Costa, Beatriz B; Morão, Barbara B; Faias, Sandra S; Veigas, Bruno B; Pereira, Lucília Pebre LP; Albuquerque, Cristina C; Maio, Rui R; Cravo, Marília M; Fernandes, Alexandra R AR; Baptista, Pedro Viana PV

Publication Date: 2023-04-25

Variant appearance in text: KRAS: G13D

PubMed Link: 37097304

Variant Present in the following documents:

• Main text
• 216_2023_Article_4696.pdf

View BVdb publication page

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Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways.

Scientific Reports

Quinn, Leonard M LM; Haldenby, Sam S; Antzcak, Philip P; Fowler, Anna A; Bullock, Katie K; Kenny, John J; Gilbert, Timothy T; Andrews, Timothy T; Diaz-Nieto, Rafael R; Fenwick, Stephen S; Jones, Robert R; Costello-Goldring, Eithne E; Poston, Graeme G; Greenhalf, William W; Palmer, Daniel D; Malik, Hassan H; Goldring, Chris C

Publication Date: 2023-04-24

Variant appearance in text: KRAS: Gly13Asp

PubMed Link: 37095160

Variant Present in the following documents:

• Main text
• 41598_2023_Article_33096.pdf

View BVdb publication page

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Guidance for clinicians and patients with non-small cell lung cancer in the time of precision medicine.

Frontiers In Oncology

Villaruz, Liza C LC; Socinski, Mark A MA; Weiss, Jared J

Publication Date: 2023

Variant appearance in text: KRAS: G13D

PubMed Link: 37077826

Variant Present in the following documents:

• Main text
• fonc-13-1124167.pdf

View BVdb publication page

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Adoptive neoantigen-reactive T cell therapy: improvement strategies and current clinical researches.

Biomarker Research

Huang, Ruichen R; Zhao, Bi B; Hu, Shi S; Zhang, Qian Q; Su, Xiaoping X; Zhang, Wei W

Publication Date: 2023-04-17

Variant appearance in text: KRAS: G13D

PubMed Link: 37062844

Variant Present in the following documents:

• Main text
• 40364_2023_Article_478.pdf

View BVdb publication page

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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature

Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C

Publication Date: 2023-04-13

Variant appearance in text: KRAS: G13D

PubMed Link: 37055640

Variant Present in the following documents:

• EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18

View BVdb publication page

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Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine

Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M

Publication Date: 2023-04-11

Variant appearance in text: KRAS: G13D

PubMed Link: 37039257

Variant Present in the following documents:

• Main text
• CAM4-12-11686.pdf

View BVdb publication page

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RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status.

Oncogene

Dorard, Coralie C; Madry, Claire C; Buhard, Olivier O; Toifl, Stefanie S; Didusch, Sebastian S; Ratovomanana, Toky T; Letourneur, Quentin Q; Dolznig, Helmut H; Garnett, Mathew J MJ; Duval, Alex A; Baccarini, Manuela M

Publication Date: 2023-04-05

Variant appearance in text: KRAS: G13D

PubMed Link: 37020037

Variant Present in the following documents:

• 41388_2023_2683_MOESM1_ESM.pdf

View BVdb publication page

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ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1.

The Biochemical Journal

Balmanno, Kathryn K; Kidger, Andrew M AM; Byrne, Dominic P DP; Sale, Matthew J MJ; Nassman, Nejma N; Eyers, Patrick A PA; Cook, Simon J SJ

Publication Date: 2023-04-05

Variant appearance in text: KRAS: G13D

PubMed Link: 37018014

Variant Present in the following documents:

• Main text
• BCJ-480-587.pdf

View BVdb publication page

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Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma.

Journal Of Experimental & Clinical Cancer Research : Cr

Ramzy, George M GM; Norkin, Maxim M; Koessler, Thibaud T; Voirol, Lionel L; Tihy, Mathieu M; Hany, Dina D; McKee, Thomas T; Ris, Frédéric F; Buchs, Nicolas N; Docquier, Mylène M; Toso, Christian C; Rubbia-Brandt, Laura L; Bakalli, Gaetan G; Guerrier, Stéphane S; Huelsken, Joerg J; Nowak-Sliwinska, Patrycja P

Publication Date: 2023-04-03

Variant appearance in text: KRAS: G13D

PubMed Link: 37013646

Variant Present in the following documents:

• Main text
• 13046_2023_Article_2650.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: KRAS: G13D

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: KRAS: Gly13Asp

PubMed Link: 37004022

Variant Present in the following documents:

• Main text

View BVdb publication page

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Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.

Communications Biology

Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL

Publication Date: 2023-03-31

Variant appearance in text: KRAS: 38G>A; G13D; rs112445441

PubMed Link: 37002311

Variant Present in the following documents:

• 42003_2023_4732_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Inducible protein degradation as a strategy to identify Phosphoprotein Phosphatase 6 substrates in RAS-mutant colorectal cancer cells.

Biorxiv : The Preprint Server For Biology

Mariano, Natasha C NC; Rusin, Scott F SF; Nasa, Isha I; Kettenbach, Arminja N AN

Publication Date: 2023-03-25

Variant appearance in text: KRAS: G13D

PubMed Link: 36993243

Variant Present in the following documents:

• Main text
• nihpp-2023.03.25.534211v1.pdf

View BVdb publication page

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The Use of Liquid Biopsy in the Molecular Analysis of Plasma Compared to the Tumour Tissue from a Patient with Brain Metastasis: A Case Report.

Medicina (Kaunas, Lithuania)

Aran, Veronica V; Zogbi, Vinicius Mansur VM; Miranda, Renan Lyra RL; Andreiuolo, Felipe F; Silva Canedo, Nathalie Henriques NH; Nazaré, Carolina Victor CV; Niemeyer Filho, Paulo P; Neto, Vivaldo Moura VM

Publication Date: 2023-02-25

Variant appearance in text: KRAS: G13D

PubMed Link: 36984460

Variant Present in the following documents:

• Main text
• medicina-59-00459.pdf

View BVdb publication page

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Association of DNA Promoter Methylation and BRAF Mutation in Thyroid Cancer.

Current Oncology (Toronto, Ont.)

Jasmine, Farzana F; Aschebrook-Kilfoy, Briseis B; Rahman, Mohammad M MM; Zaagman, Garrett G; Grogan, Raymon H RH; Kamal, Mohammed M; Ahsan, Habibul H; Kibriya, Muhammad G MG

Publication Date: 2023-03-02

Variant appearance in text: rs112445441

PubMed Link: 36975440

Variant Present in the following documents:

• Main text
• curroncol-30-00227.pdf

View BVdb publication page

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Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.

Cancer Research Communications

Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J

Publication Date: 2022-10

Variant appearance in text: KRAS: 38G>A; G13D

PubMed Link: 36969747

Variant Present in the following documents:

• crc-22-0258-s08.xlsx, sheet 1
• crc-22-0258-s09.xlsx, sheet 1

View BVdb publication page

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Case Report: MSS colorectal extrahepatic (non-liver) metastases as the dominant population for immunotherapy combined with multi-target tyrosine kinase inhibitors.

Frontiers In Oncology

Liu, Jiayin J; Li, Dan D; Han, Jing J; Zhang, Yin Y; Zhang, Xue X; Fan, Zhisong Z; Feng, Li L; Wang, Long L; Jin, Hui H; Zuo, Jing J; Wang, Yudong Y

Publication Date: 2023

Variant appearance in text: KRAS: G13D

PubMed Link: 36969012

Variant Present in the following documents:

• Main text
• fonc-13-1091669.pdf

View BVdb publication page

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Editorial: Computational drug discovery for targeting of protein-protein interfaces-Volume II.

Frontiers In Chemistry

Morra, Giulia G; Meli, Massimiliano M; Moroni, Elisabetta E; Pandini, Alessandro A

Publication Date: 2023

Variant appearance in text: K-Ras4B: G13D

PubMed Link: 36959875

Variant Present in the following documents:

• fchem-11-1171597.pdf

View BVdb publication page

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: KRAS: G13D

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

View BVdb publication page

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RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.

Nature

Jbara, Amina A; Lin, Kuan-Ting KT; Stossel, Chani C; Siegfried, Zahava Z; Shqerat, Haya H; Amar-Schwartz, Adi A; Elyada, Ela E; Mogilevsky, Maxim M; Raitses-Gurevich, Maria M; Johnson, Jared L JL; Yaron, Tomer M TM; Ovadia, Ofek O; Jang, Gun Ho GH; Danan-Gotthold, Miri M; Cantley, Lewis C LC; Levanon, Erez Y EY; Gallinger, Steven S; Krainer, Adrian R AR; Golan, Talia T; Karni, Rotem R

Publication Date: 2023-03-22

Variant appearance in text: KRAS: G13D

PubMed Link: 36949200

Variant Present in the following documents:

• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 4
• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 1
• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

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