Publications:

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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm

Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y

Publication Date: 2023-06

Variant appearance in text: KRAS: G13R

PubMed Link: 37250144

Variant Present in the following documents:

• Main text

View BVdb publication page

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Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology

Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2023-04-28

Variant appearance in text: KRAS: G13R

PubMed Link: 37207265

Variant Present in the following documents:

• Main text
• nihpp-2023.04.28.536249v1.pdf

View BVdb publication page

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KRAS mutation: The booster of pancreatic ductal adenocarcinoma transformation and progression.

Frontiers In Cell And Developmental Biology

Zhang, Zining Z; Zhang, Heng H; Liao, Xiang X; Tsai, Hsiang-I HI

Publication Date: 2023

Variant appearance in text: KRAS: G13R

PubMed Link: 37152291

Variant Present in the following documents:

• Main text
• fcell-11-1147676.pdf

View BVdb publication page

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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature

Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C

Publication Date: 2023-04-13

Variant appearance in text: KRAS: G13R

PubMed Link: 37055640

Variant Present in the following documents:

• EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18

View BVdb publication page

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Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ.

Cancers

Spella, Magda M; Ntaliarda, Giannoula G; Skiadas, Georgios G; Lamort, Anne-Sophie AS; Vreka, Malamati M; Marazioti, Antonia A; Lilis, Ioannis I; Bouloukou, Eleni E; Giotopoulou, Georgia A GA; Pepe, Mario A A MAA; Weiss, Stefanie A I SAI; Petrera, Agnese A; Hauck, Stefanie M SM; Koch, Ina I; Lindner, Michael M; Hatz, Rudolph A RA; Behr, Juergen J; Arendt, Kristina A M KAM; Giopanou, Ioanna I; Brunn, David D; Savai, Rajkumar R; Jenne, Dieter E DE; de Château, Maarten M; Yull, Fiona E FE; Blackwell, Timothy S TS; Stathopoulos, Georgios T GT

Publication Date: 2023-03-20

Variant appearance in text: KRAS: G13R

PubMed Link: 36980752

Variant Present in the following documents:

• cancers-15-01866.pdf

View BVdb publication page

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Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.

Nature Medicine

Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW

Publication Date: 2023-03-16

Variant appearance in text: KRAS: G13R

PubMed Link: 36928815

Variant Present in the following documents:

• 41591_2023_2255_MOESM3_ESM.xlsx, sheet 5

View BVdb publication page

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Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations.

Biorxiv : The Preprint Server For Biology

Yan, Hong H; Talty, Ronan R; Jain, Abhishek A; Cai, Yuping Y; Zheng, Jie J; Shen, Xinyi X; Muca, Engjel E; Paty, Philip B PB; Bosenberg, Marcus W MW; Khan, Sajid A SA; Johnson, Caroline H CH

Publication Date: 2023-03-01

Variant appearance in text: KRAS: G13R

PubMed Link: 36909561

Variant Present in the following documents:

• Main text

View BVdb publication page

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KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences

Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN

Publication Date: 2023-03-02

Variant appearance in text: KRAS: G13R

PubMed Link: 36902296

Variant Present in the following documents:

• ijms-24-04868.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: KRAS: 37G>C; Gly13Arg

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Preclinical Models of Follicular Cell-Derived Thyroid Cancer: An Overview from Cancer Cell Lines to Mouse Models.

Endocrinology And Metabolism (Seoul, Korea)

Jeon, Min Ji MJ; Haugen, Bryan R BR

Publication Date: 2022-12

Variant appearance in text: KRAS: G13R

PubMed Link: 36604954

Variant Present in the following documents:

• enm-2022-1636.pdf

View BVdb publication page

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Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors.

Npj Precision Oncology

Lee, Jessica K JK; Sivakumar, Smruthy S; Schrock, Alexa B AB; Madison, Russell R; Fabrizio, David D; Gjoerup, Ole O; Ross, Jeffrey S JS; Frampton, Garrett M GM; Napalkov, Pavel P; Montesion, Meagan M; Schutzman, Jennifer L JL; Ye, Xin X; Hegde, Priti S PS; Nagasaka, Misako M; Oxnard, Geoffrey R GR; Sokol, Ethan S ES; Ou, Sai-Hong Ignatius SI; Shi, Zhen Z

Publication Date: 2022-12-09

Variant appearance in text: KRAS: G13R

PubMed Link: 36494601

Variant Present in the following documents:

• 41698_2022_Article_334.pdf

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients.

Cell Genomics

Wu, Hua-Jun HJ; Temko, Daniel D; Maliga, Zoltan Z; Moreira, Andre L AL; Sei, Emi E; Minussi, Darlan Conterno DC; Dean, Jamie J; Lee, Charlotte C; Xu, Qiong Q; Hochart, Guillaume G; Jacobson, Connor A CA; Yapp, Clarence C; Schapiro, Denis D; Sorger, Peter K PK; Seeley, Erin H EH; Navin, Nicholas N; Downey, Robert J RJ; Michor, Franziska F

Publication Date: 2022-08-10

Variant appearance in text: KRAS: G13R

PubMed Link: 36419822

Variant Present in the following documents:

• NIHMS1829514-supplement-2.xlsx, sheet 1

View BVdb publication page

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Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes.

Nature Communications

Bolouri, Hamid H; Ries, Rhonda E RE; Wiedeman, Alice E AE; Hylkema, Tiffany T; Scheiding, Sheila S; Gersuk, Vivian H VH; O'Brien, Kimberly K; Nguyen, Quynh-Anh QA; Smith, Jenny L JL; Alice Long, S S; Meshinchi, Soheil S

Publication Date: 2022-11-23

Variant appearance in text: KRAS: G13R

PubMed Link: 36418348

Variant Present in the following documents:

• 41467_2022_34965_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Cell Reports

Ramakrishnan, Gopalakrishnan G; Parajuli, Parash P; Singh, Pura P; Friend, Creighton C; Hurwitz, Eric E; Prunier, Celine C; Razzaque, Mohammed S MS; Xu, Keli K; Atfi, Azeddine A

Publication Date: 2022-11-08

Variant appearance in text: KRAS: G13R

PubMed Link: 36351408

Variant Present in the following documents:

• NIHMS1848910-supplement-2.xlsx, sheet 3
• NIHMS1848910-supplement-2.xlsx, sheet 1

View BVdb publication page

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: KRAS: 37G>C; Gly13Arg

PubMed Link: 36344948

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10235.pdf

View BVdb publication page

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 36333792

Variant Present in the following documents:

• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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The Genetic Architecture of Vascular Anomalies: Current Data and Future Therapeutic Perspectives Correlated with Molecular Mechanisms.

International Journal Of Molecular Sciences

Butnariu, Lăcrămioara Ionela LI; Gorduza, Eusebiu Vlad EV; Florea, Laura L; Țarcă, Elena E; Moisă, Ștefana Maria ȘM; Trandafir, Laura Mihaela LM; Stoleriu, Simona S; Bădescu, Minerva Codruța MC; Luca, Alina-Costina AC; Popa, Setalia S; Radu, Iulian I; Cojocaru, Elena E

Publication Date: 2022-10-13

Variant appearance in text: KRAS: 37G>C; Gly13Arg

PubMed Link: 36293054

Variant Present in the following documents:

• Main text
• ijms-23-12199.pdf

View BVdb publication page

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Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cancers

Cekani, Elona E; Epistolio, Samantha S; Dazio, Giulia G; Cefalì, Marco M; Wannesson, Luciano L; Frattini, Milo M; Froesch, Patrizia P

Publication Date: 2022-08-24

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 36077640

Variant Present in the following documents:

• cancers-14-04103.pdf

View BVdb publication page

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A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non-Small Cell Lung Cancer.

Cancer Research

Woo, Xing Yi XY; Srivastava, Anuj A; Mack, Philip C PC; Graber, Joel H JH; Sanderson, Brian J BJ; Lloyd, Michael W MW; Chen, Mandy M; Domanskyi, Sergii S; Gandour-Edwards, Regina R; Tsai, Rebekah A RA; Keck, James J; Cheng, Mingshan M; Bundy, Margaret M; Jocoy, Emily L EL; Riess, Jonathan W JW; Holland, William W; Grubb, Stephen C SC; Peterson, James G JG; Stafford, Grace A GA; Paisie, Carolyn C; Neuhauser, Steven B SB; Karuturi, R Krishna Murthy RKM; George, Joshy J; Simons, Allen K AK; Chavaree, Margaret M; Tepper, Clifford G CG; Goodwin, Neal N; Airhart, Susan D SD; Lara, Primo N PN; Openshaw, Thomas H TH; Liu, Edison T ET; Gandara, David R DR; Bult, Carol J CJ

Publication Date: 2022-11-15

Variant appearance in text: KRAS: G13R

PubMed Link: 36069866

Variant Present in the following documents:

• can-22-0948_table_s1_suppst1.xlsx, sheet 1

View BVdb publication page

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Megakaryopoiesis impairment through acute innate immune signaling activation by azacitidine.

The Journal Of Experimental Medicine

Okoye-Okafor, Ujunwa Cynthia UC; Javarappa, Komal K KK; Tsallos, Dimitrios D; Saad, Joseph J; Yang, Daozheng D; Zhang, Chi C; Benard, Lumie L; Thiruthuvanathan, Victor J VJ; Cole, Sally S; Ruiz, Stephen S; Tatiparthy, Madhuri M; Choudhary, Gaurav G; DeFronzo, Stefanie S; Bartholdy, Boris A BA; Pallaud, Celine C; Ramos, Pedro Marques PM; Shastri, Aditi A; Verma, Amit A; Heckman, Caroline A CA; Will, Britta B

Publication Date: 2022-11-07

Variant appearance in text: KRAS: G13R

PubMed Link: 36053753

Variant Present in the following documents:

• JEM_20212228_TableS1.xlsx, sheet 1

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer.

Frontiers In Oncology

Wanigasooriya, Kasun K; Barros-Silva, Joao D JD; Tee, Louise L; El-Asrag, Mohammed E ME; Stodolna, Agata A; Pickles, Oliver J OJ; Stockton, Joanne J; Bryer, Claire C; Hoare, Rachel R; Whalley, Celina M CM; Tyler, Robert R; Sillo, Toritseju T; Yau, Christopher C; Ismail, Tariq T; Beggs, Andrew D AD

Publication Date: 2022

Variant appearance in text: KRAS: G13R

PubMed Link: 35860583

Variant Present in the following documents:

• Main text
• fonc-12-920444.pdf

View BVdb publication page

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Somatic targeted mutation profiling of colorectal cancer precursor lesions.

Bmc Medical Genomics

Dos Santos, Wellington W; Dos Reis, Mariana Bisarro MB; Porto, Jun J; de Carvalho, Ana Carolina AC; Matsushita, Marcus M; Oliveira, Gabriela G; Syrjänen, Kari K; Reis, Rui Manuel RM; Guimarães, Denise Peixoto DP

Publication Date: 2022-06-28

Variant appearance in text: KRAS: G13R; rs121913535

PubMed Link: 35761395

Variant Present in the following documents:

• 12920_2022_1294_MOESM6_ESM.xlsx, sheet 1
• 12920_2022_1294_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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FBXW7 and Its Downstream NOTCH Pathway Could be Potential Indicators of Organ-Free Metastasis in Colorectal Cancer.

Frontiers In Oncology

Li, Dongzheng D; Jiang, Shiye S; Zhou, Xin X; Si, Chengshuai C; Shao, Peng P; Jiang, Qian Q; Zhu, Liuqing L; Shen, Lu L; Meng, Qi Q; Yin, Jiani C JC; Shao, Yang Y; Sun, Yueming Y; Yang, Liu L

Publication Date: 2021

Variant appearance in text: KRAS: G13R

PubMed Link: 35712679

Variant Present in the following documents:

• Main text
• fonc-11-783564.pdf

View BVdb publication page

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Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer

Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E

Publication Date: 2022-05-03

Variant appearance in text: rs121913535

PubMed Link: 35505283

Variant Present in the following documents:

• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 8
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 7
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 5
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 3
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 4
• 12885_2022_9619_MOESM1_ESM.xlsx, sheet 9

View BVdb publication page

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Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics

Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R

Publication Date: 2022-04-25

Variant appearance in text: KRAS: G13R

PubMed Link: 35468810

Variant Present in the following documents:

• 12920_2022_1235_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Preclinical Models for Acquired Resistance to Third-Generation EGFR Inhibitors in NSCLC: Functional Studies and Drug Combinations Used to Overcome Resistance.

Frontiers In Oncology

Mahfoudhi, Emna E; Ricordel, Charles C; Lecuyer, Gwendoline G; Mouric, Cécile C; Lena, Hervé H; Pedeux, Rémy R

Publication Date: 2022

Variant appearance in text: KRAS: G13R

PubMed Link: 35463360

Variant Present in the following documents:

• Main text

View BVdb publication page

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: G13R

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: KRAS: 37G>C; Gly13Arg

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1

View BVdb publication page

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Syringocystadenocarcinoma Papilliferum in a Fifteen-Year-Old Girl: A Case Report and Review of the Literature.

Case Reports In Dermatological Medicine

Halsey, Jordan N JN; Faith, Esteban Fernandez EF; Logan, Suzanna J SJ; Shenoy, Archana A; Schieffer, Kathleen M KM; Cottrell, Catherine E CE; Lillis, Anna P AP; Aldrink, Jennifer H JH; Setty, Bhuvana A BA; Pearson, Gregory D GD

Publication Date: 2022

Variant appearance in text: KRAS: Gly13Arg

PubMed Link: 35154835

Variant Present in the following documents:

• CRIDM2022-8076649.pdf

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs121913535

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 6
• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs121913535

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 6
• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach.

Cell Reports

McFall, Thomas T; Stites, Edward C EC

Publication Date: 2021-12-14

Variant appearance in text: KRAS: G13R

PubMed Link: 34910921

Variant Present in the following documents:

• Main text
• nihms-1764636.pdf
• NIHMS1764636-supplement-2.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KRAS: G13R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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A novel xenonucleic acid-mediated molecular clamping technology for early colorectal cancer screening.

Plos One

Sun, Qing Q; Pastor, Larry L; Du, Jinwei J; Powell, Michael J MJ; Zhang, Aiguo A; Bodmer, Walter W; Wu, Jianzhong J; Zheng, Shu S; Sha, Michael Y MY

Publication Date: 2021

Variant appearance in text: KRAS: 37G>C

PubMed Link: 34610014

Variant Present in the following documents:

• Main text

View BVdb publication page

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Infrequent RAS mutation is not associated with specific histological phenotype in gliomas.

Bmc Cancer

Makino, Yasuhide Y; Arakawa, Yoshiki Y; Yoshioka, Ema E; Shofuda, Tomoko T; Minamiguchi, Sachiko S; Kawauchi, Takeshi T; Tanji, Masahiro M; Kanematsu, Daisuke D; Nonaka, Masahiro M; Okita, Yoshiko Y; Kodama, Yoshinori Y; Mano, Masayuki M; Hirose, Takanori T; Mineharu, Yohei Y; Miyamoto, Susumu S; Kanemura, Yonehiro Y

Publication Date: 2021-09-15

Variant appearance in text: KRAS: G13R

PubMed Link: 34525976

Variant Present in the following documents:

• Main text

View BVdb publication page

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High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.

Thoracic Cancer

Feng, Hui-Bo HB; Chen, Yu Y; Xie, Zhi Z; Jiang, Jie J; Zhong, Yu-Min YM; Guo, Wei-Bang WB; Yan, Wen-Qing WQ; Lv, Zhi-Yi ZY; Lu, Dan-Xia DX; Liang, Hong-Ling HL; Xu, Fang-Ping FP; Yang, Jin-Ji JJ; Yang, Xue-Ning XN; Zhou, Qing Q; Zhang, Dong-Kun DK; Zhang, Zhou Z; Chuai, Shao-Kun SK; Zhang, Heng-Hui HH; Wu, Yi-Long YL; Zhang, Xu-Chao XC

Publication Date: 2021-10

Variant appearance in text: KRAS: G13R

PubMed Link: 34490728

Variant Present in the following documents:

• Main text
• TCA-12-2564.pdf

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High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.

Thoracic Cancer

Feng, Hui-Bo HB; Chen, Yu Y; Xie, Zhi Z; Jiang, Jie J; Zhong, Yu-Min YM; Guo, Wei-Bang WB; Yan, Wen-Qing WQ; Lv, Zhi-Yi ZY; Lu, Dan-Xia DX; Liang, Hong-Ling HL; Xu, Fang-Ping FP; Yang, Jin-Ji JJ; Yang, Xue-Ning XN; Zhou, Qing Q; Zhang, Dong-Kun DK; Zhang, Zhou Z; Chuai, Shao-Kun SK; Zhang, Heng-Hui HH; Wu, Yi-Long YL; Zhang, Xu-Chao XC

Publication Date: 2021-10

Variant appearance in text: KRAS: G13R

PubMed Link: 34490728

Variant Present in the following documents:

• Main text
• TCA-12-2564.pdf

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: KRAS: G13R

PubMed Link: 34440110

Variant Present in the following documents:

• Main text
• biomedicines-09-00906.pdf

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Integrated genotype-phenotype analysis of long-term epilepsy-associated ganglioglioma.

Brain Pathology (Zurich, Switzerland)

Wang, Yujiao Y; Wang, Leiming L; Blümcke, Ingmar I; Zhang, Weiwei W; Fu, Yongjuan Y; Shan, Yongzhi Y; Piao, Yueshan Y; Zhao, Guoguang G

Publication Date: 2022-01

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 34355449

Variant Present in the following documents:

• Main text
• BPA-32-e13011-s002.xlsx, sheet 4

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Integrated genotype-phenotype analysis of long-term epilepsy-associated ganglioglioma.

Brain Pathology (Zurich, Switzerland)

Wang, Yujiao Y; Wang, Leiming L; Blümcke, Ingmar I; Zhang, Weiwei W; Fu, Yongjuan Y; Shan, Yongzhi Y; Piao, Yueshan Y; Zhao, Guoguang G

Publication Date: 2021-08-05

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 34355449

Variant Present in the following documents:

• Main text
• BPA-32-e13011-s002.xlsx, sheet 4

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Prognostic Value of KRAS Exon 3 and Exon 4 Mutations in Colorectal Cancer Patients.

Journal Of Cancer

Guo, Tianan T; Wu, Yuchen Y; Huang, Dan D; Jin, Yutong Y; Sheng, Weiqi W; Cai, Sanjun S; Zhou, Xiaoyan X; Zhu, Xiaoli X; Liu, Fangqi F; Xu, Ye Y

Publication Date: 2021

Variant appearance in text: KRAS: G13R

PubMed Link: 34335949

Variant Present in the following documents:

• Main text
• jcav12p5331.pdf

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Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.

Cancer Research

Yenerall, Paul P; Kollipara, Rahul K RK; Avila, Kimberley K; Peyton, Michael M; Eide, Christopher A CA; Bottomly, Daniel D; McWeeney, Shannon K SK; Liu, Yan Y; Westover, Kenneth D KD; Druker, Brian J BJ; Minna, John D JD; Kittler, Ralf R

Publication Date: 2021-09-15

Variant appearance in text: KRAS: G13R

PubMed Link: 34301758

Variant Present in the following documents:

• 4685.pdf

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Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.

Cancer Research

Yenerall, Paul P; Kollipara, Rahul K RK; Avila, Kimberley K; Peyton, Michael M; Eide, Christopher A CA; Bottomly, Daniel D; McWeeney, Shannon K SK; Liu, Yan Y; Westover, Kenneth D KD; Druker, Brian J BJ; Minna, John D JD; Kittler, Ralf R

Publication Date: 2021-09-15

Variant appearance in text: KRAS: G13R

PubMed Link: 34301758

Variant Present in the following documents:

• 4685.pdf

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The Prognostic Impact of KRAS G12C Mutation in Patients with Metastatic Colorectal Cancer: A Multicenter Retrospective Observational Study.

The Oncologist

Chida, Keigo K; Kotani, Daisuke D; Masuishi, Toshiki T; Kawakami, Takeshi T; Kawamoto, Yasuyuki Y; Kato, Kyoko K; Fushiki, Kunihiro K; Sawada, Kentaro K; Kumanishi, Ryosuke R; Shirasu, Hiromichi H; Matsubara, Yuki Y; Yuki, Satoshi S; Komatsu, Yoshito Y; Yamazaki, Kentaro K; Yoshino, Takayuki T

Publication Date: 2021-10

Variant appearance in text: KRAS: G13R

PubMed Link: 34232546

Variant Present in the following documents:

• Main text

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The Presence of Genomic Instability in Cerebrospinal Fluid in Patients with Meningeal Metastasis.

Cancer Management And Research

Wang, Peng P; Zhang, Henghui H; Chen, Peng P; Sun, Zengfeng Z; Zhang, Zhen Z; Yin, Qiang Q; Sun, Huaibo H; Yu, Jinpu J

Publication Date: 2021

Variant appearance in text: KRAS: G13R

PubMed Link: 34188538

Variant Present in the following documents:

• Main text
• cmar-13-4853.pdf

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Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Levin, Noam N; Paria, Biman C BC; Vale, Nolan R NR; Yossef, Rami R; Lowery, Frank J FJ; Parkhurst, Maria R MR; Yu, Zhiya Z; Florentin, Maria M; Cafri, Gal G; Gartner, Jared J JJ; Shindorf, Mackenzie L ML; Ngo, Lien T LT; Ray, Satyajit S; Kim, Sanghyun P SP; Copeland, Amy R AR; Robbins, Paul F PF; Rosenberg, Steven A SA

Publication Date: 2021-09-15

Variant appearance in text: KRAS: G13R

PubMed Link: 34168045

Variant Present in the following documents:

• Main text

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Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Levin, Noam N; Paria, Biman C BC; Vale, Nolan R NR; Yossef, Rami R; Lowery, Frank J FJ; Parkhurst, Maria R MR; Yu, Zhiya Z; Florentin, Maria M; Cafri, Gal G; Gartner, Jared J JJ; Shindorf, Mackenzie L ML; Ngo, Lien T LT; Ray, Satyajit S; Kim, Sanghyun P SP; Copeland, Amy R AR; Robbins, Paul F PF; Rosenberg, Steven A SA

Publication Date: 2021-09-15

Variant appearance in text: KRAS: G13R

PubMed Link: 34168045

Variant Present in the following documents:

• Main text

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Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology

Shern, Jack F JF; Selfe, Joanna J; Izquierdo, Elisa E; Patidar, Rajesh R; Chou, Hsien-Chao HC; Song, Young K YK; Yohe, Marielle E ME; Sindiri, Sivasish S; Wei, Jun J; Wen, Xinyu X; Rudzinski, Erin R ER; Barkauskas, Donald A DA; Lo, Tammy T; Hall, David D; Linardic, Corinne M CM; Hughes, Debbie D; Jamal, Sabri S; Jenney, Meriel M; Chisholm, Julia J; Brown, Rebecca R; Jones, Kristine K; Hicks, Belynda B; Angelini, Paola P; George, Sally S; Chesler, Louis L; Hubank, Michael M; Kelsey, Anna A; Gatz, Susanne A SA; Skapek, Stephen X SX; Hawkins, Douglas S DS; Shipley, Janet M JM; Khan, Javed J

Publication Date: 2021-09-10

Variant appearance in text: KRAS: G13R

PubMed Link: 34166060

Variant Present in the following documents:

• jco-39-2859.pdf

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Targeting KRAS in Solid Tumors: Current Challenges and Future Opportunities of Novel KRAS Inhibitors.

Pharmaceutics

Indini, Alice A; Rijavec, Erika E; Ghidini, Michele M; Cortellini, Alessio A; Grossi, Francesco F

Publication Date: 2021-05-04

Variant appearance in text: KRAS: G13R

PubMed Link: 34064352

Variant Present in the following documents:

• Main text

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SEMMs: Somatically Engineered Mouse Models. A New Tool for In Vivo Disease Modeling for Basic and Translational Research.

Frontiers In Oncology

Lima, Anthony A; Maddalo, Danilo D

Publication Date: 2021

Variant appearance in text: KRAS: G13R

PubMed Link: 33968774

Variant Present in the following documents:

• Main text

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Clinical and prognostic features of patients with detailed RAS/BRAF-mutant colorectal cancer in Japan.

Bmc Cancer

Ikoma, Tatsuki T; Shimokawa, Mototsugu M; Kotaka, Masahito M; Matsumoto, Toshihiko T; Nagai, Hiroki H; Boku, Shogen S; Shibata, Nobuhiro N; Yasui, Hisateru H; Satake, Hironaga H

Publication Date: 2021-05-07

Variant appearance in text: KRAS: G13R

PubMed Link: 33962575

Variant Present in the following documents:

• Main text

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A Diffusion-like Process Accommodates New Crypts During Clonal Expansion in Human Colonic Epithelium.

Gastroenterology

Olpe, Cora C; Khamis, Doran D; Chukanova, Maria M; Skoufou-Papoutsaki, Nefeli N; Kemp, Richard R; Marks, Kate K; Tatton, Cerys C; Lindskog, Cecilia C; Nicholson, Anna A; Brunton-Sim, Roxanne R; Malhotra, Shalini S; Ten Hoopen, Rogier R; Stanley, Rachael R; Winton, Douglas J DJ; Morrissey, Edward E

Publication Date: 2021-08

Variant appearance in text: KRAS: G13R

PubMed Link: 33895166

Variant Present in the following documents:

• Main text

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KRAS Mutational Regression Is Associated With Oligo-Metastatic Status and Good Prognosis in Metastatic Colorectal Cancer.

Frontiers In Oncology

Ottaiano, Alessandro A; Nasti, Guglielmo G; Santorsola, Mariachiara M; Altieri, Vincenzo V; Di Fruscio, Giuseppina G; Circelli, Luisa L; Luce, Amalia A; Cossu, Alessia Maria AM; Scognamiglio, Giosuè G; Perri, Francesco F; Correra, Marco M; Belli, Andrea A; Delrio, Paolo P; Botti, Gerardo G; Caraglia, Michele M

Publication Date: 2021

Variant appearance in text: KRAS: G13R

PubMed Link: 33854968

Variant Present in the following documents:

• Main text

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Mutation status and prognostic value of KRAS and NRAS mutations in Moroccan colon cancer patients: A first report.

Plos One

El Agy, Fatima F; El Bardai, Sanae S; El Otmani, Ihsane I; Benbrahim, Zineb Z; Karim, Ibn Majdoub Hassani MH; Mazaz, Khalid K; Benjelloun, El Bachir EB; Ousadden, Abdelmalek A; El Abkari, Mohammed M; Ibrahimi, Sidi Adil SA; Chbani, Laila L

Publication Date: 2021

Variant appearance in text: KRAS: 37G>C; G13R

PubMed Link: 33784337

Variant Present in the following documents:

• pone.0248522.pdf

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