Hill, William W; Lim, Emilia L EL; Weeden, Clare E CE; Lee, Claudia C; Augustine, Marcellus M; Chen, Kezhong K; Kuan, Feng-Che FC; Marongiu, Fabio F; Evans, Edward J EJ; Moore, David A DA; Rodrigues, Felipe S FS; Pich, Oriol O; Bakker, Bjorn B; Cha, Hongui H; Myers, Renelle R; van Maldegem, Febe F; Boumelha, Jesse J; Veeriah, Selvaraju S; Rowan, Andrew A; Naceur-Lombardelli, Cristina C; Karasaki, Takahiro T; Sivakumar, Monica M; De, Swapnanil S; Caswell, Deborah R DR; Nagano, Ai A; Black, James R M JRM; Martínez-Ruiz, Carlos C; Ryu, Min Hyung MH; Huff, Ryan D RD; Li, Shijia S; Favé, Marie-Julie MJ; Magness, Alastair A; Suárez-Bonnet, Alejandro A; Priestnall, Simon L SL; Lüchtenborg, Margreet M; Lavelle, Katrina K; Pethick, Joanna J; Hardy, Steven S; McRonald, Fiona E FE; Lin, Meng-Hung MH; Troccoli, Clara I CI; Ghosh, Moumita M; Miller, York E YE; Merrick, Daniel T DT; Keith, Robert L RL; Al Bakir, Maise M; Bailey, Chris C; Hill, Mark S MS; Saal, Lao H LH; Chen, Yilun Y; George, Anthony M AM; Abbosh, Christopher C; Kanu, Nnennaya N; Lee, Se-Hoon SH; McGranahan, Nicholas N; Berg, Christine D CD; Sasieni, Peter P; Houlston, Richard R; Turnbull, Clare C; Lam, Stephen S; Awadalla, Philip P; Grönroos, Eva E; Downward, Julian J; Jacks, Tyler T; Carlsten, Christopher C; Malanchi, Ilaria I; Hackshaw, Allan A; Litchfield, Kevin K; , ; DeGregori, James J; Jamal-Hanjani, Mariam M; Swanton, Charles C
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
The Predictive and Prognostic Role of RAS-RAF-MEK-ERK Pathway Alterations in Breast Cancer: Revision of the Literature and Comparison with the Analysis of Cancer Genomic Datasets.
Cancers
Rocca, Andrea A; Braga, Luca L; Volpe, Maria Concetta MC; Maiocchi, Serena S; Generali, Daniele D
Osimertinib+Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor Mutated MET-Amplified Non-Small Cell Lung Cancer: TATTON.
Cancer Discovery
Hartmaier, Ryan J RJ; Markovets, Aleksandra A AA; Ahn, Myung Ju MJ; Sequist, Lecia V LV; Han, Ji-Youn JY; Cho, Byoung Chul BC; Yu, Helena A HA; Kim, Sang-We SW; Yang, James Chih-Hsin JC; Lee, Jong-Seok JS; Su, Wu-Chou WC; Kowalski, Dariusz M DM; Orlov, Sergey S; Ren, Song S; Frewer, Paul P; Ou, Xiaoling X; Cross, Darren Ae DA; Kurian, Nisha N; Cantarini, Mireille M; Janne, Pasi A PA
Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC.
Jto Clinical And Research Reports
Schwartzberg, Lee S LS; Li, Gerald G; Tolba, Khaled K; Bourla, Ariel B AB; Schulze, Katja K; Gadgil, Rujuta R; Fine, Alexander A; Lofgren, Katherine T KT; Graf, Ryon P RP; Oxnard, Geoffrey R GR; Daniel, Davey D
Molecular Targets in Lung Cancer: Study of the Evolution of Biomarkers Associated with Treatment with Tyrosine Kinase Inhibitors-Has NF1 Tumor Suppressor a Key Role in Acquired Resistance?
Cancers
Alen, Begoña O BO; Estévez-Pérez, Lara S LS; Hermida-Romero, María Teresa MT; Reguera-Arias, Ana A; García-Campelo, Rosario R; de la Torre-Bravos, Mercedes M; Concha, Ángel Á
Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma.
The Oncologist
Mack, Philip C PC; Klein, Michael I MI; Ayers, Kristin L KL; Zhou, Xiang X; Guin, Sunny S; Fink, Marc M; Rossi, Michael M; Ai-Kateb, Hussam H; O'Connell, Timmy T; Hantash, Feras M FM; Oh, William K WK; Newman, Scott S; Schadt, Eric E EE; Chen, Rong R; Hirsch, Fred R FR
The Genomics of Colorectal Cancer in Populations with African and European Ancestry.
Cancer Discovery
Myer, Parvathi A PA; Lee, Jessica K JK; Madison, Russell W RW; Pradhan, Kith K; Newberg, Justin Y JY; Isasi, Carmen R CR; Klempner, Samuel J SJ; Frampton, Garrett M GM; Ross, Jeffery S JS; Venstrom, Jeffrey M JM; Schrock, Alexa B AB; Das, Sudipto S; Augenlicht, Leonard L; Verma, Amit A; Greally, John M JM; Raj, Srilakshmi M SM; Goel, Sanjay S; Ali, Siraj M SM
Comparison between Fluorimetry (Qubit) and Spectrophotometry (NanoDrop) in the Quantification of DNA and RNA Extracted from Frozen and FFPE Tissues from Lung Cancer Patients: A Real-World Use of Genomic Tests.
Cobimetinib Plus Gemcitabine: An Active Combination in KRAS G12R-Mutated Pancreatic Ductal Adenocarcinoma Patients in Previously Treated and Failed Multiple Chemotherapies.
Journal Of Pancreatic Cancer
Ardalan, Bach B; Azqueta, Jose J; Sleeman, Danny D
Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers.
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors.
Nature Communications
Gebregiworgis, Teklab T; Kano, Yoshihito Y; St-Germain, Jonathan J; Radulovich, Nikolina N; Udaskin, Molly L ML; Mentes, Ahmet A; Huang, Richard R; Poon, Betty P K BPK; He, Wenguang W; Valencia-Sama, Ivette I; Robinson, Claire M CM; Huestis, Melissa M; Miao, Jinmin J; Yeh, Jen Jen JJ; Zhang, Zhong-Yin ZY; Irwin, Meredith S MS; Lee, Jeffrey E JE; Tsao, Ming-Sound MS; Raught, Brian B; Marshall, Christopher B CB; Ohh, Michael M; Ikura, Mitsuhiko M
Comprehensive landscape and interference of clonal haematopoiesis mutations for liquid biopsy: A Chinese pan-cancer cohort.
Journal Of Cellular And Molecular Medicine
Xu, Enwu E; Su, Kai K; Zhou, Yang Y; Gong, Longlong L; Xuan, Yiwen Y; Liao, Ming M; Cao, Jiawang J; Li, Yaqian Y; Lu, Yujiao Y; Zhao, Yi Y; Chen, Fengxia F
The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border.
International Journal Of Environmental Research And Public Health
Grant, Alice Hernandez AH; Ayala-Marin, Yoshira Marie YM; Mohl, Jonathon Edward JE; Robles-Escajeda, Elisa E; Rodriguez, Georgialina G; Dutil, Julie J; Kirken, Robert Arthur RA
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Nature Communications
Bear, Adham S AS; Blanchard, Tatiana T; Cesare, Joseph J; Ford, Michael J MJ; Richman, Lee P LP; Xu, Chong C; Baroja, Miren L ML; McCuaig, Sarah S; Costeas, Christina C; Gabunia, Khatuna K; Scholler, John J; Posey, Avery D AD; O'Hara, Mark H MH; Smole, Anze A; Powell, Daniel J DJ; Garcia, Benjamin A BA; Vonderheide, Robert H RH; Linette, Gerald P GP; Carreno, Beatriz M BM
Plasma ctDNA Response Is an Early Marker of Treatment Effect in Advanced NSCLC.
Jco Precision Oncology
Cheng, Michael L ML; Lau, Christie J CJ; Milan, Marina S D MSD; Supplee, Julianna G JG; Riess, Jonathan W JW; Bradbury, Penelope A PA; Jänne, Pasi A PA; Oxnard, Geoffrey R GR; Paweletz, Cloud P CP
Profiling non-small cell lung cancer reveals that PD-L1 is associated with wild type EGFR and vascular invasion, and immunohistochemistry quantification of PD-L1 correlates weakly with RT-qPCR.
Plos One
Alwithenani, Akram A; Bethune, Drew D; Castonguay, Mathieu M; Drucker, Arik A; Flowerdew, Gordon G; Forsythe, Marika M; French, Daniel D; Fris, John J; Greer, Wenda W; Henteleff, Harry H; MacNeil, Mary M; Marignani, Paola P; Morzycki, Wojciech W; Plourde, Madelaine M; Snow, Stephanie S; Marcato, Paola P; Xu, Zhaolin Z