Variant ID: 12-25398284-C-A

NM_004985.3(KRAS):c.35G>T;(p.G12V)

This variant was identified in 3391 publications

View GRCh38 version.




Publications:


Molecular Landscape and Prognostic Biomarker Analysis of Advanced Pancreatic Cancer and Predictors of Treatment Efficacy of AG Chemotherapy.

Frontiers In Oncology
Du, Juan J; Qiu, Xin X; Lu, Changchang C; Zhu, Yahui Y; Kong, Weiwei W; Xu, Mian M; Zhang, Xin X; Tang, Min M; Chen, Jun J; Li, Qi Q; Li, Aimei A; He, Jian J; Gu, Qing Q; Wang, Lei L; Qiu, Yudong Y; Liu, Baorui B
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35664782
Variant Present in the following documents:
  • Main text
  • fonc-12-844527.pdf
View BVdb publication page



Identification of Synergistic Drug Combinations to Target KRAS-Driven Chemoradioresistant Cancers Utilizing Tumoroid Models of Colorectal Adenocarcinoma and Recurrent Glioblastoma.

Frontiers In Oncology
Gupta, Kshama K; Jones, Jeremy C JC; Farias, Virginea De Araujo VA; Mackeyev, Yuri Y; Singh, Pankaj K PK; Quiñones-Hinojosa, Alfredo A; Krishnan, Sunil S
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35664781
Variant Present in the following documents:
  • Main text
  • fonc-12-840241.pdf
View BVdb publication page



Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer.

Journal Of Experimental & Clinical Cancer Research : Cr
Yang, Lu L; Bhattacharya, Arup A; Li, Yun Y; Sexton, Sandra S; Ling, Xiang X; Li, Fengzhi F; Zhang, Yuesheng Y
Publication Date: 2022-06-02

Variant appearance in text: KRAS: G12V
PubMed Link: 35650607
Variant Present in the following documents:
  • Main text
View BVdb publication page



Corrigendum: Longitudinal Circulating Tumor DNA Profiling in Metastatic Colorectal Cancer During Anti-EGFR Therapy.

Frontiers In Oncology
Yang, Wentao W; Zou, Jianling J; Li, Ye Y; Liu, Rujiao R; Yan, Zhengqing Z; Chen, Shiqing S; Zhao, Xiaoying X; Guo, Weijian W; Huang, Mingzhu M; Li, Wenhua W; Zhu, Xiaodong X; Chen, Zhiyu Z
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35646700
Variant Present in the following documents:
  • fonc-12-903586.pdf
View BVdb publication page



Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.

Pathology Oncology Research : Por
Li, Lihong L; Song, Qianqian Q; Cao, Dandan D; Jiao, Yuchen Y; Yuan, Guangwen G; Song, Yan Y
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35645619
Variant Present in the following documents:
  • DataSheet1.xlsx
View BVdb publication page



Molecular Signatures of KRAS-Mutated Lung Adenocarcinoma: Analysis of Concomitant EGFR, ALK, STK11, and PD-L1 Status.

Clinical Pathology (Thousand Oaks, Ventura County, Calif.)
Hsu, Jim J; Annunziata, Joseph F JF; Burns, Ethan E; Bernicker, Eric H EH; Olsen, Randall J RJ; Thomas, Jessica S JS
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35634237
Variant Present in the following documents:
  • Main text
  • 10.1177_2632010X221102054.pdf
View BVdb publication page



Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases MUTYH and hOGG1 in Colorectal Cancer Patients.

International Journal Of Molecular Sciences
Kavec, Miriam J MJ; Urbanova, Marketa M; Makovicky, Pavol P; Opattová, Alena A; Tomasova, Kristyna K; Kroupa, Michal M; Kostovcikova, Klara K; Siskova, Anna A; Navvabi, Nazila N; Schneiderova, Michaela M; Vymetalkova, Veronika V; Vodickova, Ludmila L; Vodicka, Pavel P
Publication Date: 2022-05-20

Variant appearance in text: KRAS: 35G>T
PubMed Link: 35628513
Variant Present in the following documents:
  • Main text
  • ijms-23-05704.pdf
View BVdb publication page



Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer.

Cells
Osude, Chike C; Lin, Leo L; Patel, Meet M; Eckburg, Adam A; Berei, Joseph J; Kuckovic, Adijan A; Dube, Namrata N; Rastogi, Aayush A; Gautam, Shruti S; Smith, Thomas J TJ; Sreenivassappa, Shylendra B SB; Puri, Neelu N
Publication Date: 2022-05-19

Variant appearance in text: KRAS: g12v
PubMed Link: 35626731
Variant Present in the following documents:
  • cells-11-01694.pdf
View BVdb publication page



Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of β-Catenin Regardless of APC and β-Catenin Mutational Status.

Biomedicines
Garavaglia, Beatrice B; Vallino, Letizia L; Ferraresi, Alessandra A; Esposito, Andrea A; Salwa, Amreen A; Vidoni, Chiara C; Gentilli, Sergio S; Isidoro, Ciro C
Publication Date: 2022-05-13

Variant appearance in text: KRAS: G12V
PubMed Link: 35625868
Variant Present in the following documents:
  • biomedicines-10-01131.pdf
View BVdb publication page



Colorectal Cancer Heterogeneity and the Impact on Precision Medicine and Therapy Efficacy.

Biomedicines
Rosati, Gerardo G; Aprile, Giuseppe G; Colombo, Alfredo A; Cordio, Stefano S; Giampaglia, Marianna M; Cappetta, Alessandro A; Porretto, Concetta Maria CM; De Stefano, Alfonso A; Bilancia, Domenico D; Avallone, Antonio A
Publication Date: 2022-04-30

Variant appearance in text: KRAS: G12V
PubMed Link: 35625772
Variant Present in the following documents:
  • Main text
  • biomedicines-10-01035.pdf
View BVdb publication page



Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients.

Current Oncology (Toronto, Ont.)
Sasamori, Hiroki H; Nakayama, Kentaro K; Razia, Sultana S; Yamashita, Hitomi H; Ishibashi, Tomoka T; Ishikawa, Masako M; Sato, Seiya S; Nakayama, Satoru S; Otsuki, Yoshiro Y; Fujiwaki, Ritsuto R; Ishikawa, Noriyoshi N; Kyo, Satoru S
Publication Date: 2022-05-18

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 35621684
Variant Present in the following documents:
  • Main text
  • curroncol-29-00294.pdf
View BVdb publication page



KRAS/NRAS/BRAF Mutation Rate in Saudi Academic Hospital Patients With Colorectal Cancer.

Cureus
Saharti, Samah S
Publication Date: 2022-04

Variant appearance in text: KRAS: G12V
PubMed Link: 35619874
Variant Present in the following documents:
  • Main text
  • cureus-0014-00000024392.pdf
View BVdb publication page



Identification of vaccine targets & design of vaccine against SARS-CoV-2 coronavirus using computational and deep learning-based approaches.

Peerj
Abbasi, Bilal Ahmed BA; Saraf, Devansh D; Sharma, Trapti T; Sinha, Robin R; Singh, Shachee S; Sood, Shriya S; Gupta, Pranjay P; Gupta, Akshat A; Mishra, Kartik K; Kumari, Priya P; Rawal, Kamal K
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35611169
Variant Present in the following documents:
  • peerj-10-13380.pdf
View BVdb publication page



p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.

Nature Communications
Solé, Laura L; Lobo-Jarne, Teresa T; Álvarez-Villanueva, Daniel D; Alonso-Marañón, Josune J; Guillén, Yolanda Y; Guix, Marta M; Sangrador, Irene I; Rozalén, Catalina C; Vert, Anna A; Barbachano, Antonio A; Lop, Joan J; Salido, Marta M; Bellosillo, Beatriz B; García-Romero, Raquel R; Garrido, Marta M; González, Jessica J; Martínez-Iniesta, María M; López-Arribillaga, Erika E; Salazar, Ramón R; Montagut, Clara C; Torres, Ferrán F; Iglesias, Mar M; Celià-Terrassa, Toni T; Muñoz, Alberto A; Villanueva, Alberto A; Bigas, Anna A; Espinosa, Lluís L
Publication Date: 2022-05-23

Variant appearance in text: KRAS: G12V
PubMed Link: 35606354
Variant Present in the following documents:
  • 41467_2022_30382_MOESM1_ESM.pdf
View BVdb publication page



The Current Landscape of mRNA Vaccines Against Viruses and Cancer-A Mini Review.

Frontiers In Immunology
Ladak, Reese Jalal RJ; He, Alexander J AJ; Huang, Yu-Hsun YH; Ding, Yu Y
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35603213
Variant Present in the following documents:
  • Main text
  • fimmu-13-885371.pdf
View BVdb publication page



Worldwide Prevalence and Clinical Characteristics of RAS Mutations in Head and Neck Cancer: A Systematic Review and Meta-Analysis.

Frontiers In Oncology
Novoplansky, Ofra O; Jagadeeshan, Sankar S; Regev, Ohad O; Menashe, Idan I; Elkabets, Moshe M
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35600380
Variant Present in the following documents:
  • Main text
  • fonc-12-838911.pdf
View BVdb publication page



A colorectal cancer missed by colon capsule endoscopy: a case report.

Bmc Gastroenterology
MacLeod, C C; Oliphant, R R; Docherty, J G JG; Watson, A J M AJM
Publication Date: 2022-05-21

Variant appearance in text: KRAS: Gly12Val
PubMed Link: 35597907
Variant Present in the following documents:
  • Main text
  • 12876_2022_Article_2332.pdf
View BVdb publication page



Pancreatic Organoids for Regenerative Medicine and Cancer Research.

Frontiers In Cell And Developmental Biology
Casamitjana, Joan J; Espinet, Elisa E; Rovira, Meritxell M
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35592251
Variant Present in the following documents:
  • Main text
View BVdb publication page



Results of screening in early and advanced thoracic malignancies in the EORTC pan-European SPECTAlung platform.

Scientific Reports
Morfouace, M M; Novello, S S; Stevovic, A A; Dooms, C C; Janžič, U U; Berghmans, T T; Dziadziuszko, R R; Gorlia, T T; Felip, E E; Paz-Ares, L L; Mazieres, J J; O'Brien, M M; Bironzo, P P; Vansteenkiste, J J; Lacroix, L L; Dingemans, A C AC; Golfinopoulos, V V; Besse, B B
Publication Date: 2022-05-18

Variant appearance in text: KRAS: G12V
PubMed Link: 35585228
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_12056.pdf
View BVdb publication page



Targeting the "undruggable" RAS - new strategies - new hope?

Cancer Drug Resistance (Alhambra, Calif.)
Mörchen, Britta B; Shkura, Oleksandr O; Stoll, Raphael R; Helfrich, Iris I
Publication Date: 2019

Variant appearance in text: KRAS: G12V
PubMed Link: 35582595
Variant Present in the following documents:
  • cdr-2-813.pdf
View BVdb publication page



Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma.

Cancer Drug Resistance (Alhambra, Calif.)
Alonso-Peña, Marta M; Sanchez-Martin, Anabel A; Sanchon-Sanchez, Paula P; Soto-Muñiz, Meraris M; Espinosa-Escudero, Ricardo R; Marin, Jose J G JJG
Publication Date: 2019

Variant appearance in text: KRAS: 35G>T; Gly12Val
PubMed Link: 35582588
Variant Present in the following documents:
  • cdr-2-680.pdf
View BVdb publication page



Efficacy of ICIs on patients with oncogene-driven non-small cell lung cancer: a retrospective study.

Cancer Drug Resistance (Alhambra, Calif.)
Guo, Xiaojin X; Du, He H; Li, Jiayu J; Yang, Menghang M; Xiong, Anweng A; Zhang, Haiping H; Wu, Fengying F
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35582532
Variant Present in the following documents:
  • cdr-5-15.pdf
View BVdb publication page



The implication of liquid biopsies to predict chemoresistance in pancreatic cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Pietri, Elisabetta E; Balsano, Rita R; Coriano, Matilde M; Gelsomino, Fabio F; Leonardi, Francesco F; Bui, Simona S; Gnetti, Letizia L; Valle, Raffaele Dalla RD; Garajová, Ingrid I
Publication Date: 2021

Variant appearance in text: KRAS: G12V
PubMed Link: 35582309
Variant Present in the following documents:
  • cdr-4-559.pdf
View BVdb publication page



Emerging RAS-directed therapies for cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Conroy, Michael M; Cowzer, Darren D; Kolch, Walter W; Duffy, Austin G AG
Publication Date: 2021

Variant appearance in text: KRAS: G12V
PubMed Link: 35582302
Variant Present in the following documents:
  • cdr-4-543.pdf
View BVdb publication page



Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

Nature Communications
Lee, Bernard C H BCH; Robinson, Philip S PS; Coorens, Tim H H THH; Yan, Helen H N HHN; Olafsson, Sigurgeir S; Lee-Six, Henry H; Sanders, Mathijs A MA; Siu, Hoi Cheong HC; Hewinson, James J; Yue, Sarah S K SSK; Tsui, Wai Yin WY; Chan, Annie S Y ASY; Chan, Anthony K W AKW; Ho, Siu Lun SL; Campbell, Peter J PJ; Martincorena, Inigo I; Buczacki, Simon J A SJA; Yuen, Siu Tsan ST; Leung, Suet Yi SY; Stratton, Michael R MR
Publication Date: 2022-05-17

Variant appearance in text: KRAS: G12V
PubMed Link: 35581206
Variant Present in the following documents:
  • 41467_2022_Article_29920.pdf
  • 41467_2022_29920_MOESM3_ESM.xlsx
View BVdb publication page



A novel nanobody as therapeutics target for EGFR-positive colorectal cancer therapy: exploring the effects of the nanobody on SW480 cells using proteomics approach.

Proteome Science
Lamtha, Thomanai T; Krobthong, Sucheewin S; Yingchutrakul, Yodying Y; Samutrtai, Pawitrabhorn P; Gerner, Christopher C; Tabtimmai, Lueacha L; Choowongkomon, Kiattawee K
Publication Date: 2022-05-16

Variant appearance in text: KRAS: G12V
PubMed Link: 35578244
Variant Present in the following documents:
  • 12953_2022_Article_190.pdf
View BVdb publication page



Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer
Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X
Publication Date: 2022-05-16

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 35578198
Variant Present in the following documents:
  • 12885_2022_9602_MOESM9_ESM.xlsx
View BVdb publication page



The paradigm shift in treatment from Covid-19 to oncology with mRNA vaccines.

Cancer Treatment Reviews
Wei, Jiao J; Hui, Ai-Min AM
Publication Date: 2022-05-05

Variant appearance in text: KRAS: G12V
PubMed Link: 35576777
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma.

Frontiers In Oncology
Khadse, Anand A; Haakensen, Vilde D VD; Silwal-Pandit, Laxmi L; Hamfjord, Julian J; Micke, Patrick P; Botling, Johan J; Brustugun, Odd Terje OT; Lingjærde, Ole Christian OC; Helland, Åslaug Å; Kure, Elin H EH
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35574381
Variant Present in the following documents:
  • fonc-12-873532.pdf
View BVdb publication page



Development of a Novel Reference Material for Tumor Mutational Burden Measurement Based on CRISPR/Cas9 Technology.

Frontiers In Oncology
Peng, Rongxue R; Lin, Guigao G; Li, Lin L; Li, Jinming J
Publication Date: 2022

Variant appearance in text: KRAS: G12v
PubMed Link: 35574377
Variant Present in the following documents:
  • fonc-12-845636.pdf
View BVdb publication page



The Tumor Suppressor Kinase LKB1: Metabolic Nexus.

Frontiers In Cell And Developmental Biology
Bourouh, Mohammed M; Marignani, Paola A PA
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35573694
Variant Present in the following documents:
  • fcell-10-881297.pdf
View BVdb publication page



XNAs: A Troubleshooter for Nucleic Acid Sensing.

Acs Omega
Mana, Tanushree T; Bhattacharya, Budhaditya B; Lahiri, Hiya H; Mukhopadhyay, Rupa R
Publication Date: 2022-05-10

Variant appearance in text: KRAS: G12V
PubMed Link: 35571783
Variant Present in the following documents:
  • ao2c00581.pdf
View BVdb publication page



KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer.

Cancers
Eklund, Ella A EA; Wiel, Clotilde C; Fagman, Henrik H; Akyürek, Levent M LM; Raghavan, Sukanya S; Nyman, Jan J; Hallqvist, Andreas A; Sayin, Volkan I VI
Publication Date: 2022-04-20

Variant appearance in text: KRAS: G12V
PubMed Link: 35565194
Variant Present in the following documents:
  • cancers-14-02063.pdf
View BVdb publication page



Prognostic and Immunotherapeutic Roles of KRAS in Pan-Cancer.

Cells
Yang, Kaixin K; Li, Chengyun C; Liu, Yang Y; Gu, Xueyan X; Jiang, Longchang L; Shi, Lei L
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G12V
PubMed Link: 35563733
Variant Present in the following documents:
  • cells-11-01427.pdf
View BVdb publication page



Preparation of Duplex Sequencing Libraries for Archival Paraffin-Embedded Tissue Samples Using Single-Strand-Specific Nuclease P1.

International Journal Of Molecular Sciences
Mitiushkina, Natalia V NV; Yanus, Grigory A GA; Kuligina, Ekatherina Sh ES; Laidus, Tatiana A TA; Romanko, Alexandr A AA; Kholmatov, Maksim M MM; Ivantsov, Alexandr O AO; Aleksakhina, Svetlana N SN; Imyanitov, Evgeny N EN
Publication Date: 2022-04-21

Variant appearance in text: KRAS: G12V
PubMed Link: 35562977
Variant Present in the following documents:
  • ijms-23-04586.pdf
View BVdb publication page



PD-L1 Expression in Non-Small Cell Lung Cancer Specimens: Association with Clinicopathological Factors and Molecular Alterations.

International Journal Of Molecular Sciences
Mansour, Mohammed S I MSI; Malmros, Karina K; Mager, Ulrich U; Ericson Lindquist, Kajsa K; Hejny, Kim K; Holmgren, Benjamin B; Seidal, Tomas T; Dejmek, Annika A; Dobra, Katalin K; Planck, Maria M; Brunnström, Hans H
Publication Date: 2022-04-19

Variant appearance in text: KRAS: G12V
PubMed Link: 35562908
Variant Present in the following documents:
  • ijms-23-04517.pdf
View BVdb publication page



SNAT7 regulates mTORC1 via macropinocytosis.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Meng, Delong D; Yang, Qianmei Q; Jeong, Mi-Hyeon MH; Curukovic, Adna A; Tiwary, Shweta S; Melick, Chase H CH; Lama-Sherpa, Tshering D TD; Wang, Huanyu H; Huerta-Rosario, Mariela M; Urquhart, Greg G; Zacharias, Lauren G LG; Lewis, Cheryl C; DeBerardinis, Ralph J RJ; Jewell, Jenna L JL
Publication Date: 2022-05-17

Variant appearance in text: KRAS: G12V
PubMed Link: 35561222
Variant Present in the following documents:
  • pnas.202123261.pdf
  • pnas.2123261119.sapp.pdf
View BVdb publication page



Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes.

Frontiers In Immunology
Keller, Grant L J GLJ; Weiss, Laura I LI; Baker, Brian M BM
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35547730
Variant Present in the following documents:
  • fimmu-13-887759.pdf
View BVdb publication page



Comprehensive Molecular Profiling of Colorectal Cancer With Situs Inversus Totalis by Next-Generation Sequencing.

Frontiers In Oncology
Li, Hongsen H; Gong, Liu L; Cheng, Huanqing H; Wang, Huina H; Zhang, Xiaochen X; Rao, Chuangzhou C; Song, Zhangfa Z; Wang, Da D; Lou, Haizhou H; Lou, Feng F; Cao, Shanbo S; Pan, Hongming H; Fang, Yong Y
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35530355
Variant Present in the following documents:
  • fonc-12-813253.pdf
View BVdb publication page



Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells.

Oncoimmunology
Subbarayan, Karthikeyan K; Massa, Chiara C; Leisz, Sandra S; Steven, André A; Bethmann, Daniel D; Biehl, Katharina K; Wickenhauser, Claudia C; Seliger, Barbara B
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35529675
Variant Present in the following documents:
  • KONI_11_2069214.pdf
View BVdb publication page



Targeting Mutant Kirsten Rat Sarcoma Viral Oncogene Homolog in Non-Small Cell Lung Cancer: Current Difficulties, Integrative Treatments and Future Perspectives.

Frontiers In Pharmacology
Li, Jia-Xin JX; Li, Run-Ze RZ; Ma, Lin-Rui LR; Wang, Peng P; Xu, Dong-Han DH; Huang, Jie J; Li, Li-Qi LQ; Tang, Ling L; Xie, Ying Y; Leung, Elaine Lai-Han EL; Yan, Pei-Yu PY
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35517800
Variant Present in the following documents:
  • fphar-13-875330.pdf
View BVdb publication page



Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer
Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E
Publication Date: 2022-05-03

Variant appearance in text: rs121913529
PubMed Link: 35505283
Variant Present in the following documents:
  • 12885_2022_9619_MOESM1_ESM.xlsx
View BVdb publication page



Clonal Hematopoiesis of Indeterminate Potential and Diabetic Kidney Disease: A Nested Case-Control Study.

Kidney International Reports
Denicolò, Sara S; Vogi, Verena V; Keller, Felix F; Thöni, Stefanie S; Eder, Susanne S; Heerspink, Hiddo J L HJL; Rosivall, László L; Wiecek, Andrzej A; Mark, Patrick B PB; Perco, Paul P; Leierer, Johannes J; Kronbichler, Andreas A; Steger, Marion M; Schwendinger, Simon S; Zschocke, Johannes J; Mayer, Gert G; Jukic, Emina E
Publication Date: 2022-04

Variant appearance in text: KRAS: 35G>T; Gly12Val
PubMed Link: 35497780
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Tumor cell malignancy: A complex trait built through reciprocal interactions between tumors and tissue-body system.

Iscience
Feunteun, Jean J; Ostyn, Pauline P; Delaloge, Suzette S
Publication Date: 2022-05-20

Variant appearance in text: KRAS: G12V
PubMed Link: 35494254
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Efficacy of first-line immune checkpoint inhibitors in patients with advanced NSCLC with KRAS, MET, FGFR, RET, BRAF, and HER2 alterations.

Thoracic Cancer
Uehara, Yuji Y; Watanabe, Kageaki K; Hakozaki, Taiki T; Yomota, Makiko M; Hosomi, Yukio Y
Publication Date: 2022-05-02

Variant appearance in text: KRAS: G12V
PubMed Link: 35491960
Variant Present in the following documents:
  • Main text
  • TCA-13-1703.pdf
View BVdb publication page



Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Sun, Na N; Tran, Benjamin V BV; Peng, Zishan Z; Wang, Jing J; Zhang, Ceng C; Yang, Peng P; Zhang, Tiffany X TX; Widjaja, Josephine J; Zhang, Ryan Y RY; Xia, Wenxi W; Keir, Alexandra A; She, Jia-Wei JW; Yu, Hsiao-Hua HH; Shyue, Jing-Jong JJ; Zhu, Hongguang H; Agopian, Vatche G VG; Pei, Renjun R; Tomlinson, James S JS; Toretsky, Jeffrey A JA; Jonas, Steven J SJ; Federman, Noah N; Lu, Shaohua S; Tseng, Hsian-Rong HR; Zhu, Yazhen Y
Publication Date: 2022-03-09

Variant appearance in text: KRAS: G12V
PubMed Link: 35486030
Variant Present in the following documents:
  • ADVS-9-2105853-s001.pdf
  • ADVS-9-2105853.pdf
View BVdb publication page



Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutations.

Cell Reports Methods
Choi, Jaewon J; Goulding, Scott P SP; Conn, Brandon P BP; McGann, Christopher D CD; Dietze, Jared L JL; Kohler, Jessica J; Lenkala, Divya D; Boudot, Antoine A; Rothenberg, Daniel A DA; Turcott, Paul J PJ; Srouji, John R JR; Foley, Kendra C KC; Rooney, Michael S MS; van Buuren, Marit M MM; Gaynor, Richard B RB; Abelin, Jennifer G JG; Addona, Terri A TA; Juneja, Vikram R VR
Publication Date: 2021-09-27

Variant appearance in text: KRAS: G12V
PubMed Link: 35474673
Variant Present in the following documents:
  • mmc3.pdf
  • mmc1.pdf
  • main.pdf
View BVdb publication page



Multi-targeting of K-Ras domains and mutations by peptide and small molecule inhibitors.

Plos Computational Biology
Poorebrahim, Mansour M; Abazari, Mohammad Foad MF; Moradi, Leila L; Shahbazi, Behzad B; Mahmoudi, Reza R; Kalhor, Hourieh H; Askari, Hassan H; Teimoori-Toolabi, Ladan L
Publication Date: 2022-04

Variant appearance in text: K-Ras4B: G12V
PubMed Link: 35472201
Variant Present in the following documents:
  • pcbi.1009962.pdf
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Analytical validation and initial clinical testing of quantitative microscopic evaluation for PD-L1 and HLA I expression on circulating tumor cells from patients with non-small cell lung cancer.

Biomarker Research
Schehr, Jennifer L JL; Sethakorn, Nan N; Schultz, Zachery D ZD; Hernandez, Camila I CI; Bade, Rory M RM; Eyzaguirre, Diego D; Singh, Anupama A; Niles, David J DJ; Henderson, Leslie L; Warrick, Jay W JW; Berry, Scott M SM; Sundling, Kaitlin E KE; Beebe, David J DJ; Leal, Ticiana A TA; Lang, Joshua M JM
Publication Date: 2022-04-25

Variant appearance in text: KRAS: G12V
PubMed Link: 35468853
Variant Present in the following documents:
  • 40364_2022_370_MOESM1_ESM.pdf
View BVdb publication page



Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics
Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R
Publication Date: 2022-04-25

Variant appearance in text: KRAS: G12V
PubMed Link: 35468810
Variant Present in the following documents:
  • 12920_2022_1235_MOESM3_ESM.xlsx
  • 12920_2022_1235_MOESM2_ESM.xlsx
View BVdb publication page



Synergistic blocking of RAS downstream signaling and epigenetic pathway in KRAS mutant pancreatic cancer.

Aging
Zhang, Xiaofei X; Mao, Tiebo T; Xu, Haiyan H; Li, Shumin S; Yue, Ming M; Ma, Jingyu J; Yao, Jiayu J; Wang, Yongchao Y; Zhang, Xiao X; Ge, Weiyu W; Wang, Yanling Y; Shentu, Daiyuan D; Wang, Liwei L
Publication Date: 2022-04-25

Variant appearance in text: KRAS: G12V
PubMed Link: 35468095
Variant Present in the following documents:
  • aging-14-204031.pdf
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Clinicopathological Significance of PTEN Expression and Its Prognostic Effect in Colorectal Adenocarcinoma Patients.

Iranian Journal Of Pathology
Mirzapour Abbas Abadi, Zohreh Z; Samiee Rad, Fatemeh F; Hamedi Asl, Dariush D; Rahmani, Babak B; Soleimani Dodaran, Mahmood M; Peimani, Amir A
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35463728
Variant Present in the following documents:
  • ijp-17-150.pdf
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Concurrent RAS and RAS/BRAF V600E Variants in Colorectal Cancer: More Frequent Than Expected? A Case Report.

Frontiers In Oncology
Zelli, Veronica V; Parisi, Alessandro A; Patruno, Leonardo L; Cannita, Katia K; Ficorella, Corrado C; Luzi, Carla C; Compagnoni, Chiara C; Zazzeroni, Francesca F; Alesse, Edoardo E; Tessitore, Alessandra A
Publication Date: 2022

Variant appearance in text: KRAS: 35G>T
PubMed Link: 35463316
Variant Present in the following documents:
  • fonc-12-863639.pdf
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Acquired Concurrent EGFR T790M and Driver Gene Resistance From EGFR-TKIs Hampered Osimertinib Efficacy in Advanced Lung Adenocarcinoma: Case Reports.

Frontiers In Pharmacology
Zeng, Yue Y; Feng, Yuanqing Y; Fu, Guihua G; Jiang, Junlan J; Liu, Xiaohan X; Pan, Yue Y; Hu, Chunhong C; Liu, Xianling X; Wu, Fang F
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35462930
Variant Present in the following documents:
  • fphar-13-838247.pdf
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Inhibitory Response to CK II Inhibitor Silmitasertib and CDKs Inhibitor Dinaciclib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.

International Journal Of Molecular Sciences
Ma, Yixuan Y; Sender, Sina S; Sekora, Anett A; Kong, Weibo W; Bauer, Peter P; Ameziane, Najim N; Krake, Susann S; Radefeldt, Mandy M; Al-Ali, Ruslan R; Weiss, Frank Ulrich FU; Lerch, Markus M MM; Parveen, Alisha A; Zechner, Dietmar D; Junghanss, Christian C; Murua Escobar, Hugo H
Publication Date: 2022-04-16

Variant appearance in text: KRAS: 35G>T; Gly12Val
PubMed Link: 35457227
Variant Present in the following documents:
  • ijms-23-04409.pdf
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The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.

International Journal Of Molecular Sciences
Ma, Yixuan Y; Sender, Sina S; Sekora, Anett A; Kong, Weibo W; Bauer, Peter P; Ameziane, Najim N; Al-Ali, Ruslan R; Krake, Susann S; Radefeldt, Mandy M; Weiss, Frank Ulrich FU; Lerch, Markus M MM; Parveen, Alisha A; Zechner, Dietmar D; Junghanss, Christian C; Murua Escobar, Hugo H
Publication Date: 2022-04-13

Variant appearance in text: KRAS: 35G>T; Gly12Val
PubMed Link: 35457111
Variant Present in the following documents:
  • ijms-23-04295.pdf
View BVdb publication page



Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.

International Journal Of Molecular Sciences
Calabrese, Fiorella F; Pezzuto, Federica F; Lunardi, Francesca F; Fortarezza, Francesco F; Tzorakoleftheraki, Sofia-Eleni SE; Resi, Maria Vittoria MV; Tiné, Mariaenrica M; Pasello, Giulia G; Hofman, Paul P
Publication Date: 2022-04-09

Variant appearance in text: KRAS: G12V
PubMed Link: 35456982
Variant Present in the following documents:
  • ijms-23-04164.pdf
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KRAS: A Druggable Target in Colon Cancer Patients.

International Journal Of Molecular Sciences
Negri, Francesca F; Bottarelli, Lorena L; de'Angelis, Gian Luigi GL; Gnetti, Letizia L
Publication Date: 2022-04-08

Variant appearance in text: KRAS: G12V
PubMed Link: 35456940
Variant Present in the following documents:
  • ijms-23-04120.pdf
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Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gastrointestinal Tract: A Case Series.

Healthcare (Basel, Switzerland)
Guerrera, Luigi Pio LP; Suarato, Gabriella G; Napolitano, Rossella R; Perrone, Alessandra A; Caputo, Vincenza V; Ventriglia, Anna A; Martini, Giulia G; Della Corte, Carminia Maria CM; Orditura, Michele M; Martinelli, Erika E; Ciardiello, Fortunato F; Montella, Marco M; Franco, Renato R; Troiani, Teresa T; Napolitano, Stefania S
Publication Date: 2022-04-11

Variant appearance in text: KRAS: G12V
PubMed Link: 35455885
Variant Present in the following documents:
  • healthcare-10-00708.pdf
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Circulating Nucleic Acids as Novel Biomarkers for Pancreatic Ductal Adenocarcinoma.

Cancers
McGowan, Ryan R; Sally, Áine Á; McCabe, Anthony A; Moran, Brian Michael BM; Finn, Karen K
Publication Date: 2022-04-17

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 35454933
Variant Present in the following documents:
  • cancers-14-02027.pdf
View BVdb publication page



Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer.

Science Advances
Ferguson, Scott S; Yang, Katherine S KS; Zelga, Piotr P; Liss, Andrew S AS; Carlson, Jonathan C T JCT; Del Castillo, Carlos Fernandez CF; Weissleder, Ralph R
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G12V
PubMed Link: 35452280
Variant Present in the following documents:
  • sciadv.abm3453_sm.pdf
  • sciadv.abm3453.pdf
View BVdb publication page



Integrative Analysis of Pharmacokinetic and Metabolomic Profiles for Predicting Metabolic Phenotype and Drug Exposure Caused by Sotorasib in Rats.

Frontiers In Oncology
Du, Ping P; Liu, Lihong L; Hu, Ting T; An, Zhuoling Z
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35449573
Variant Present in the following documents:
  • fonc-12-778035.pdf
View BVdb publication page



Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity.

Nature Communications
Shi, Xiaohan X; Li, Yunguang Y; Yuan, Qiuyue Q; Tang, Shijie S; Guo, Shiwei S; Zhang, Yehan Y; He, Juan J; Zhang, Xiaoyu X; Han, Ming M; Liu, Zhuang Z; Zhu, Yiqin Y; Gao, Suizhi S; Wang, Huan H; Xu, Xiongfei X; Zheng, Kailian K; Jing, Wei W; Chen, Luonan L; Wang, Yong Y; Jin, Gang G; Gao, Dong D
Publication Date: 2022-04-21

Variant appearance in text: KRAS: G12V
PubMed Link: 35449156
Variant Present in the following documents:
  • 41467_2022_29857_MOESM5_ESM.xlsx
View BVdb publication page



Longitudinal Study of Circulating Biomarkers in Patients with Resectable Pancreatic Ductal Adenocarcinoma.

Biosensors
Dopico, Pablo J PJ; Le, Minh-Chau N MN; Burgess, Benjamin B; Yang, Zhijie Z; Zhao, Yu Y; Wang, Youxiang Y; George, Thomas J TJ; Fan, Z Hugh ZH
Publication Date: 2022-03-30

Variant appearance in text: KRAS: G12V
PubMed Link: 35448266
Variant Present in the following documents:
  • biosensors-12-00206.pdf
View BVdb publication page



Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use.

Plos One
Shi, Zonggao Z; Lopez, Jacqueline J; Kalliney, William W; Sutton, Bobbie B; Simpson, Joyce J; Maggert, Kevin K; Liu, Sheng S; Wan, Jun J; Stack, M Sharon MS
Publication Date: 2022

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 35446881
Variant Present in the following documents:
  • pone.0266914.pdf
View BVdb publication page



Synergistic combination of PMBA and 5-fluorouracil (5-FU) in targeting mutant KRAS in 2D and 3D colorectal cancer cells.

Heliyon
Qayum, Arem A; Magotra, Asmita A; Shah, Syed Mohmad SM; Nandi, Utpal U; Sharma, P R PR; Shah, Bhahwal Ali BA; Singh, Shashank Kumar SK
Publication Date: 2022-04

Variant appearance in text: KRAS: G12V
PubMed Link: 35445157
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



TP53 Co-Mutations in Advanced EGFR-Mutated Non-Small Cell Lung Cancer: Prognosis and Therapeutic Strategy for Cancer Therapy.

Frontiers In Oncology
Liu, Surui S; Yu, Jin J; Zhang, Hui H; Liu, Jie J
Publication Date: 2022

Variant appearance in text: KRAS: G12V
PubMed Link: 35444951
Variant Present in the following documents:
  • fonc-12-860563.pdf
View BVdb publication page



Simultaneous monitoring of disease and microbe dynamics through plasma DNA sequencing in pediatric patients with acute lymphoblastic leukemia.

Science Advances
Barsan, Valentin V; Xia, Yuntao Y; Klein, David D; Gonzalez-Pena, Veronica V; Youssef, Sarah S; Inaba, Yuki Y; Mahmud, Ousman O; Natarajan, Sivaraman S; Agarwal, Vibhu V; Pang, Yakun Y; Autry, Robert R; Pui, Ching-Hon CH; Inaba, Hiroto H; Evans, William W; Gawad, Charles C
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G12V
PubMed Link: 35442732
Variant Present in the following documents:
  • sciadv.abj1360.pdf
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An atlas of posttranslational modifications on RNA binding proteins.

Nucleic Acids Research
England, Whitney E WE; Wang, Jingtian J; Chen, Siwei S; Baldi, Pierre P; Flynn, Ryan A RA; Spitale, Robert C RC
Publication Date: 2022-04-19

Variant appearance in text: KRAS: G12V
PubMed Link: 35438783
Variant Present in the following documents:
  • gkac243.pdf
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Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types.

Scientific Reports
Seo, Ha-Young HY; Kim, Soon-Chan SC; Roh, Woo-Lee WL; Shin, Young-Kyoung YK; Kim, Soyeon S; Kim, Dong-Wan DW; Kim, Tae Min TM; Ku, Ja-Lok JL
Publication Date: 2022-04-15

Variant appearance in text: KRAS: G12V
PubMed Link: 35428753
Variant Present in the following documents:
  • 41598_2022_Article_10318.pdf
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A Liquid Biopsy-Based Approach for Monitoring Treatment Response in Post-Operative Colorectal Cancer Patients.

International Journal Of Molecular Sciences
Barták, Barbara Kinga BK; Fodor, Tamás T; Kalmár, Alexandra A; Nagy, Zsófia Brigitta ZB; Zsigrai, Sára S; Szigeti, Krisztina Andrea KA; Valcz, Gábor G; Igaz, Péter P; Dank, Magdolna M; Takács, István I; Molnár, Béla B
Publication Date: 2022-03-29

Variant appearance in text: KRAS: G12V
PubMed Link: 35409133
Variant Present in the following documents:
  • ijms-23-03774.pdf
View BVdb publication page



Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies.

International Journal Of Molecular Sciences
Shetu, Shaila A SA; Bandyopadhyay, Debasish D
Publication Date: 2022-03-28

Variant appearance in text: KRAS: G12V
PubMed Link: 35409064
Variant Present in the following documents:
  • ijms-23-03706.pdf
View BVdb publication page



Exosomes in the Treatment of Pancreatic Cancer: A Moonshot to PDAC Treatment?

International Journal Of Molecular Sciences
Papadakos, Stavros P SP; Dedes, Nikolaos N; Pergaris, Alexandros A; Gazouli, Maria M; Theocharis, Stamatios S
Publication Date: 2022-03-25

Variant appearance in text: KRAS: G12V
PubMed Link: 35408980
Variant Present in the following documents:
  • ijms-23-03620.pdf
View BVdb publication page



Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma.

Cancers
Clowers, Michael J MJ; Moghaddam, Seyed Javad SJ
Publication Date: 2022-03-31

Variant appearance in text: KRAS: G12V
PubMed Link: 35406557
Variant Present in the following documents:
  • cancers-14-01785.pdf
View BVdb publication page