KRAS c.35G>T ;(p.G12V)

Variant ID: 12-25398284-C-A

NM_004985.3(KRAS):c.35G>T;(p.G12V)

This variant was identified in 3645 publications

View GRCh38 version.




Publications:


The CD73 immune checkpoint promotes tumor cell metabolic fitness.

Elife
Allard, David D; Cousineau, Isabelle I; Ma, Eric H EH; Allard, Bertrand B; Bareche, Yacine Y; Fleury, Hubert H; Stagg, John J
Publication Date: 2023-06-01

Variant appearance in text: KRAS: G12V
PubMed Link: 37261423
Variant Present in the following documents:
  • elife-84508.pdf
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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm
Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y
Publication Date: 2023-06

Variant appearance in text: KRAS: G12V
PubMed Link: 37250144
Variant Present in the following documents:
  • Main text
  • MCO2-4-e285.pdf
View BVdb publication page



Effect of Secretion Efficiency of Mutant KRAS Neoantigen by Lactococcus lactis on the Immune Response of a Mucosal Vaccine Delivery Vehicle Targeting Colorectal Cancer.

International Journal Of Molecular Sciences
Alias, Nur Aqlili Riana NAR; Hoo, Winfrey Pui Yee WPY; Siak, Pui Yan PY; Othman, Siti Sarah SS; Mohammed Alitheen, Noorjahan Banu NB; In, Lionel Lian Aun LLA; Abdul Rahim, Raha R; Song, Adelene Ai-Lian AA
Publication Date: 2023-05-18

Variant appearance in text: KRAS: G12V
PubMed Link: 37240273
Variant Present in the following documents:
  • Main text
  • ijms-24-08928.pdf
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Clinicopathological Characteristics and Mutational Landscape of APC, HOXB13, and KRAS among Rwandan Patients with Colorectal Cancer.

Current Issues In Molecular Biology
Manirakiza, Felix F; Rutaganda, Eric E; Yamada, Hidetaka H; Iwashita, Yuji Y; Rugwizangoga, Belson B; Seminega, Benoit B; Dusabejambo, Vincent V; Ntakirutimana, Gervais G; Ruhangaza, Deogratias D; Uwineza, Annette A; Shinmura, Kazuya K; Sugimura, Haruhiko H
Publication Date: 2023-05-16

Variant appearance in text: KRAS: Gly12Val
PubMed Link: 37232746
Variant Present in the following documents:
  • Main text
  • cimb-45-00277.pdf
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Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS.

Signal Transduction And Targeted Therapy
Yin, Guowei G; Huang, Jing J; Petela, Johnny J; Jiang, Hongmei H; Zhang, Yuetong Y; Gong, Siqi S; Wu, Jiaxin J; Liu, Bei B; Shi, Jianyou J; Gao, Yijun Y
Publication Date: 2023-05-23

Variant appearance in text: KRAS: G12V
PubMed Link: 37221195
Variant Present in the following documents:
  • Main text
  • 41392_2023_Article_1441.pdf
View BVdb publication page



Determinants of tumor immune evasion: the role of T cell exposed motif frequency and mutant amino acid exposure.

Frontiers In Immunology
Homan, E Jane EJ; Bremel, Robert D RD
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37215122
Variant Present in the following documents:
  • Main text
  • fimmu-14-1155679.pdf
View BVdb publication page



Efficacy and safety of combined immunotherapy and antiangiogenic therapy for advanced non-small cell lung cancer: a real-world observation study.

Bmc Pulmonary Medicine
Ma, Ke K; Guo, Qianqian Q; Li, Xingya X
Publication Date: 2023-05-19

Variant appearance in text: KRAS: G12V
PubMed Link: 37208639
Variant Present in the following documents:
  • Main text
  • 12890_2023_Article_2470.pdf
View BVdb publication page



Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology
Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT
Publication Date: 2023-04-28

Variant appearance in text: KRAS: G12V
PubMed Link: 37207265
Variant Present in the following documents:
  • Main text
  • media-1.pdf
  • nihpp-2023.04.28.536249v1.pdf
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The role of molecular testing in pancreatic cancer.

Therapeutic Advances In Gastroenterology
Zhen, David B DB; Safyan, Rachael A RA; Konick, Eric Q EQ; Nguyen, Ryan R; Prichard, Colin C CC; Chiorean, E Gabriela EG
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37197396
Variant Present in the following documents:
  • Main text
  • 10.1177_17562848231171456.pdf
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Intrinsic features of the cancer cell as drivers of immune checkpoint blockade response and refractoriness.

Frontiers In Immunology
Ursino, Chiara C; Mouric, Cécile C; Gros, Laurent L; Bonnefoy, Nathalie N; Faget, Julien J
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37180110
Variant Present in the following documents:
  • fimmu-14-1170321.pdf
View BVdb publication page



Krüppel-like Factors 4 and 5 in Colorectal Tumorigenesis.

Cancers
Lee, Esther E; Cheung, Jacky J; Bialkowska, Agnieszka B AB
Publication Date: 2023-04-24

Variant appearance in text: KRAS: G12V
PubMed Link: 37173904
Variant Present in the following documents:
  • Main text
  • cancers-15-02430.pdf
View BVdb publication page



The efficacy of immune checkpoint inhibitors in biliary tract cancer with KRAS mutation.

Therapeutic Advances In Gastroenterology
Jeong, Sun Young SY; Hong, Jung Yong JY; Park, Joon Oh JO; Park, Young Suk YS; Lim, Ho Yeong HY; Jang, Jae Yeon JY; Jeon, Youngkyung Y; Kim, Seung Tae ST
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37163165
Variant Present in the following documents:
  • Main text
  • 10.1177_17562848231170484.pdf
View BVdb publication page



KRAS mutation: The booster of pancreatic ductal adenocarcinoma transformation and progression.

Frontiers In Cell And Developmental Biology
Zhang, Zining Z; Zhang, Heng H; Liao, Xiang X; Tsai, Hsiang-I HI
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37152291
Variant Present in the following documents:
  • Main text
  • fcell-11-1147676.pdf
View BVdb publication page



Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.

Jama Neurology
Khoshkhoo, Sattar S; Wang, Yilan Y; Chahine, Yasmine Y; Erson-Omay, E Zeynep EZ; Robert, Stephanie M SM; Kiziltug, Emre E; Damisah, Eyiyemisi C EC; Nelson-Williams, Carol C; Zhu, Guangya G; Kong, Wenna W; Huang, August Yue AY; Stronge, Edward E; Phillips, H Westley HW; Chhouk, Brian H BH; Bizzotto, Sara S; Chen, Ming Hui MH; Adikari, Thiuni N TN; Ye, Zimeng Z; Witkowski, Tom T; Lai, Dulcie D; Lee, Nadine N; Lokan, Julie J; Scheffer, Ingrid E IE; Berkovic, Samuel F SF; Haider, Shozeb S; Hildebrand, Michael S MS; Yang, Edward E; Gunel, Murat M; Lifton, Richard P RP; Richardson, R Mark RM; Blümcke, Ingmar I; Alexandrescu, Sanda S; Huttner, Anita A; Heinzen, Erin L EL; Zhu, Jidong J; Poduri, Annapurna A; DeLanerolle, Nihal N; Spencer, Dennis D DD; Lee, Eunjung Alice EA; Walsh, Christopher A CA; Kahle, Kristopher T KT
Publication Date: 2023-05-01

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 37126322
Variant Present in the following documents:
  • Main text
  • jamaneurol-e230473.pdf
View BVdb publication page



Establishment of patient-derived tumor organoids to functionally inform treatment decisions in metastatic colorectal cancer.

Esmo Open
Martini, G G; Belli, V V; Napolitano, S S; Ciaramella, V V; Ciardiello, D D; Belli, A A; Izzo, F F; Avallone, A A; Selvaggi, F F; Menegon Tasselli, F F; Santaniello, W W; Franco, R R; Puig, I I; Ramirez, L L; Chicote, I I; Mancuso, F F; Caratu, G G; Serres, X X; Fasani, R R; Jimenez, J J; Ros, J J; Baraibar, I I; Mulet, N N; Della Corte, C M CM; Troiani, T T; Vivancos, A A; Dienstmann, R R; Elez, E E; Palmer, H G HG; Tabernero, J J; Martinelli, E E; Ciardiello, F F; Argilés, G G
Publication Date: 2023-04-26

Variant appearance in text: KRAS: G12V
PubMed Link: 37119788
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Planning adaptive treatment by longitudinal response assessment implementing MR imaging, liquid biopsy and analysis of microenvironment during neoadjuvant treatment of rectal cancer (PRIMO).

Medicine
Wurschi, Georg W GW; Güllmar, Daniel D; Gaßler, Nikolaus N; Clement, Joachim J; Kesselmeier, Miriam M; Müller-Wurschi, Julia J JJ; Settmacher, Utz U; Mothes, Henning H; Helfritzsch, Herry H; Liebe, Yves Y; Franiel, Tobias T; Mäurer, Matthias A MA; Ernst, Thomas T; Nicolay, Nils H NH; Wittig, Andrea A
Publication Date: 2023-04-25

Variant appearance in text: KRAS: G12V
PubMed Link: 37115093
Variant Present in the following documents:
  • Main text
  • medi-102-e33575.pdf
View BVdb publication page



CodeBreak 200: Sotorasib Has Not Broken the KRASG12C Enigma Code.

Lung Cancer (Auckland, N.Z.)
Zhang, Shannon S SS; Lee, Alexandria A; Nagasaka, Misako M
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37101895
Variant Present in the following documents:
  • Main text
  • lctt-14-27.pdf
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Combining the amplification refractory mutation system and high-resolution melting analysis for KRAS mutation detection in clinical samples.

Analytical And Bioanalytical Chemistry
Oliveira, Beatriz B BB; Costa, Beatriz B; Morão, Barbara B; Faias, Sandra S; Veigas, Bruno B; Pereira, Lucília Pebre LP; Albuquerque, Cristina C; Maio, Rui R; Cravo, Marília M; Fernandes, Alexandra R AR; Baptista, Pedro Viana PV
Publication Date: 2023-04-25

Variant appearance in text: KRAS: G12V
PubMed Link: 37097304
Variant Present in the following documents:
  • Main text
  • 216_2023_Article_4696.pdf
View BVdb publication page



Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways.

Scientific Reports
Quinn, Leonard M LM; Haldenby, Sam S; Antzcak, Philip P; Fowler, Anna A; Bullock, Katie K; Kenny, John J; Gilbert, Timothy T; Andrews, Timothy T; Diaz-Nieto, Rafael R; Fenwick, Stephen S; Jones, Robert R; Costello-Goldring, Eithne E; Poston, Graeme G; Greenhalf, William W; Palmer, Daniel D; Malik, Hassan H; Goldring, Chris C
Publication Date: 2023-04-24

Variant appearance in text: KRAS: Gly12Val
PubMed Link: 37095160
Variant Present in the following documents:
  • Main text
View BVdb publication page



Durable Response after Repeat Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in a Patient with Extensive Mucinous Adenocarcinoma of the Appendix.

Diseases (Basel, Switzerland)
Kaakour, Dalia D; Ward, Garrett G; Senthil, Maheswari M; Dayyani, Farshid F
Publication Date: 2023-04-06

Variant appearance in text: KRAS: G12V
PubMed Link: 37092442
Variant Present in the following documents:
  • Main text
  • diseases-11-00060.pdf
View BVdb publication page



Guidance for clinicians and patients with non-small cell lung cancer in the time of precision medicine.

Frontiers In Oncology
Villaruz, Liza C LC; Socinski, Mark A MA; Weiss, Jared J
Publication Date: 2023

Variant appearance in text: KRAS: G12V
PubMed Link: 37077826
Variant Present in the following documents:
  • Main text
  • fonc-13-1124167.pdf
View BVdb publication page



Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1 -mutated endometrial cancer.

Biorxiv : The Preprint Server For Biology
Corr, Bradley R BR; Moroney, Marisa R MR; Woodruff, Elizabeth E; Watson, Zachary L ZL; Jordan, Kimberly R KR; Danhorn, Thomas T; Bailey, Courtney C; Wolsky, Rebecca J RJ; Bitler, Benjamin G BG
Publication Date: 2023-04-06

Variant appearance in text: KRAS: G12V
PubMed Link: 37066339
Variant Present in the following documents:
  • media-2.xlsx, sheet 1
View BVdb publication page



Somatic and germline aberrations in homologous recombination repair genes in Chinese prostate cancer patients.

Frontiers In Oncology
Liu, Yixiao Y; Jin, Bo B; Shen, Cheng C; Gao, Xianshu X; Qi, Xin X; Ma, Mingwei M; Li, Hongzhen H; Hao, Han H; Tang, Qi Q; Yang, Kaiwei K; Mi, Yue Y; Guan, Jie J; Feng, Xuero X; He, Zhisong Z; Li, Haixia H; Yu, Wei W
Publication Date: 2023

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 37064136
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



Adoptive neoantigen-reactive T cell therapy: improvement strategies and current clinical researches.

Biomarker Research
Huang, Ruichen R; Zhao, Bi B; Hu, Shi S; Zhang, Qian Q; Su, Xiaoping X; Zhang, Wei W
Publication Date: 2023-04-17

Variant appearance in text: KRAS: G12V
PubMed Link: 37062844
Variant Present in the following documents:
  • Main text
  • 40364_2023_Article_478.pdf
View BVdb publication page



Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature
Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C
Publication Date: 2023-04-13

Variant appearance in text: KRAS: G12V
PubMed Link: 37055640
Variant Present in the following documents:
  • EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18
View BVdb publication page



Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine
Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M
Publication Date: 2023-04-11

Variant appearance in text: KRAS: G12V
PubMed Link: 37039257
Variant Present in the following documents:
  • Main text
  • CAM4-12-11686.pdf
View BVdb publication page



Genomic landscape and clinical features of rare subtypes of pancreatic cancer: analysis with the national database of Japan.

Journal Of Gastroenterology
Sakakida, Tomoki T; Ishikawa, Takeshi T; Doi, Toshifumi T; Morita, Ryuichi R; Kataoka, Seita S; Miyake, Hayato H; Yamaguchi, Kanji K; Moriguchi, Michihisa M; Sogame, Yoshio Y; Yasuda, Hiroaki H; Iwasaku, Masahiro M; Konishi, Hideyuki H; Takayama, Koichi K; Itoh, Yoshito Y
Publication Date: 2023-04-07

Variant appearance in text: KRAS: G12V
PubMed Link: 37029223
Variant Present in the following documents:
  • Main text
  • 535_2023_Article_1986.pdf
View BVdb publication page



Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer.

Journal Of Medicinal Chemistry
Brindani, Nicoletta N; Vuong, Linh M LM; Acquistapace, Isabella Maria IM; La Serra, Maria Antonietta MA; Ortega, José Antonio JA; Veronesi, Marina M; Bertozzi, Sine Mandrup SM; Summa, Maria M; Girotto, Stefania S; Bertorelli, Rosalia R; Armirotti, Andrea A; Ganesan, Anand K AK; De Vivo, Marco M
Publication Date: 2023-04-07

Variant appearance in text: KRAS: Gly12Val
PubMed Link: 37026468
Variant Present in the following documents:
  • Main text
  • jm3c00276.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: KRAS: G12V
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 4
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
View BVdb publication page



Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer
Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J
Publication Date: 2023-03-31

Variant appearance in text: KRAS: Gly12Val
PubMed Link: 37004022
Variant Present in the following documents:
  • Main text
  • 12885_2023_Article_10674.pdf
View BVdb publication page



Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.

Communications Biology
Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL
Publication Date: 2023-03-31

Variant appearance in text: KRAS: 35G>T; G12V; rs121913529
PubMed Link: 37002311
Variant Present in the following documents:
  • 42003_2023_4732_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Nature Communications
Li, Lingling L; Jiang, Dongxian D; Liu, Hui H; Guo, Chunmei C; Zhao, Rui R; Zhang, Qiao Q; Xu, Chen C; Qin, Zhaoyu Z; Feng, Jinwen J; Liu, Yang Y; Wang, Haixing H; Chen, Weijie W; Zhang, Xue X; Li, Bin B; Bai, Lin L; Tian, Sha S; Tan, Subei S; Yu, Zixiang Z; Chen, Lingli L; Huang, Jie J; Zhao, Jian-Yuan JY; Hou, Yingyong Y; Ding, Chen C
Publication Date: 2023-03-29

Variant appearance in text: KRAS: G12V; rs121913529
PubMed Link: 36991000
Variant Present in the following documents:
  • 41467_2023_37221_MOESM5_ESM.xlsx, sheet 3
View BVdb publication page



The Use of Liquid Biopsy in the Molecular Analysis of Plasma Compared to the Tumour Tissue from a Patient with Brain Metastasis: A Case Report.

Medicina (Kaunas, Lithuania)
Aran, Veronica V; Zogbi, Vinicius Mansur VM; Miranda, Renan Lyra RL; Andreiuolo, Felipe F; Silva Canedo, Nathalie Henriques NH; Nazaré, Carolina Victor CV; Niemeyer Filho, Paulo P; Neto, Vivaldo Moura VM
Publication Date: 2023-02-25

Variant appearance in text: KRAS: G12V
PubMed Link: 36984460
Variant Present in the following documents:
  • Main text
  • medicina-59-00459.pdf
View BVdb publication page



KRAS mutations and endometriosis burden of disease.

The Journal Of Pathology. Clinical Research
Orr, Natasha L NL; Albert, Arianne A; Liu, Yang Doris YD; Lum, Amy A; Hong, JooYoon J; Ionescu, Catalina L CL; Senz, Janine J; Nazeran, Tayyebeh M TM; Lee, Anna F AF; Noga, Heather H; Lawrenson, Kate K; Allaire, Catherine C; Williams, Christina C; Bedaiwy, Mohamed A MA; Anglesio, Michael S MS; Yong, Paul J PJ
Publication Date: 2023-03-28

Variant appearance in text: KRAS: 35G>T; G12V
PubMed Link: 36977195
Variant Present in the following documents:
  • CJP2-9-302.pdf
View BVdb publication page