Variant ID: 12-25398284-C-T

NM_004985.3(KRAS):c.35G>A;(p.G12D)

This variant was identified in 5584 publications

View GRCh38 version.




Publications:


Molecular Landscape and Prognostic Biomarker Analysis of Advanced Pancreatic Cancer and Predictors of Treatment Efficacy of AG Chemotherapy.

Frontiers In Oncology
Du, Juan J; Qiu, Xin X; Lu, Changchang C; Zhu, Yahui Y; Kong, Weiwei W; Xu, Mian M; Zhang, Xin X; Tang, Min M; Chen, Jun J; Li, Qi Q; Li, Aimei A; He, Jian J; Gu, Qing Q; Wang, Lei L; Qiu, Yudong Y; Liu, Baorui B
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35664782
Variant Present in the following documents:
  • Main text
  • fonc-12-844527.pdf
View BVdb publication page



The Role of Nonapoptotic Programmed Cell Death - Ferroptosis, Necroptosis, and Pyroptosis - in Pancreatic Ductal Adenocarcinoma Treatment.

Frontiers In Oncology
Hsu, Sheng-Kai SK; Chu, Yi-Hsuan YH; Syue, Wun-Jyun WJ; Lin, Hugo You-Hsien HY; Chang, Wen-Tsan WT; Chen, Jeff Yi-Fu JY; Wu, Chang-Yi CY; Yen, Chia-Hung CH; Cheng, Kai-Chun KC; Chiu, Chien-Chih CC
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35664778
Variant Present in the following documents:
  • Main text
  • fonc-12-872883.pdf
View BVdb publication page



Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization.

National Science Review
Li, Jin-Tao JT; Li, Kai-Yue KY; Su, Ying Y; Shen, Yuan Y; Lei, Ming-Zhu MZ; Zhang, Fan F; Yin, Miao M; Chen, Zheng-Jun ZJ; Wen, Wen-Yu WY; Hu, Wei-Guo WG; Su, Dan D; Qu, Jia J; Lei, Qun-Ying QY
Publication Date: 2022-05

Variant appearance in text: KRAS: G12D
PubMed Link: 35663242
Variant Present in the following documents:
  • Main text
  • nwab212.pdf
View BVdb publication page



Primary sigmoid squamous cell carcinoma with liver metastasis: A case report.

World Journal Of Clinical Cases
Li, Xin-Yang XY; Teng, Gen G; Zhao, Xing X; Zhu, Cui-Min CM
Publication Date: 2022-05-16

Variant appearance in text: KRAS: G12D
PubMed Link: 35663075
Variant Present in the following documents:
  • WJCC-10-4608.pdf
View BVdb publication page



Durable complete response to neoantigen-loaded dendritic-cell vaccine following anti-PD-1 therapy in metastatic gastric cancer.

Npj Precision Oncology
Guo, Zengqing Z; Yuan, Yuan Y; Chen, Chao C; Lin, Jing J; Ma, Qiwang Q; Liu, Geng G; Gao, Yan Y; Huang, Ying Y; Chen, Ling L; Chen, Li-Zhu LZ; Huang, Yu-Fang YF; Wang, Hailun H; Li, Bo B; Chen, Yu Y; Zhang, Xi X
Publication Date: 2022-06-03

Variant appearance in text: KRAS: G12D
PubMed Link: 35661819
Variant Present in the following documents:
  • Main text
View BVdb publication page



Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer.

Journal Of Experimental & Clinical Cancer Research : Cr
Yang, Lu L; Bhattacharya, Arup A; Li, Yun Y; Sexton, Sandra S; Ling, Xiang X; Li, Fengzhi F; Zhang, Yuesheng Y
Publication Date: 2022-06-02

Variant appearance in text: KRAS: G12D
PubMed Link: 35650607
Variant Present in the following documents:
  • Main text
  • 13046_2022_Article_2389.pdf
View BVdb publication page



Investigating Cutaneous Squamous Cell Carcinoma in vitro and in vivo: Novel 3D Tools and Animal Models.

Frontiers In Medicine
Quadri, Marika M; Marconi, Alessandra A; Sandhu, Simran K SK; Kiss, Alexi A; Efimova, Tatiana T; Palazzo, Elisabetta E
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35646967
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pan-Cancer Single-Cell Analysis Reveals the Core Factors and Pathway in Specific Cancer Stem Cells of Upper Gastrointestinal Cancer.

Frontiers In Bioengineering And Biotechnology
Li, Leijie L; Zhang, Yujia Y; Ren, Yongyong Y; Cheng, Zhiwei Z; Zhang, Yuening Y; Wang, Xinbo X; Zhao, Hongyu H; Lu, Hui H
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35646860
Variant Present in the following documents:
  • Main text
  • fbioe-10-849798.pdf
View BVdb publication page



LKB1: Can We Target an Hidden Target? Focus on NSCLC.

Frontiers In Oncology
Ndembe, Gloriana G; Intini, Ilenia I; Perin, Elisa E; Marabese, Mirko M; Caiola, Elisa E; Mendogni, Paolo P; Rosso, Lorenzo L; Broggini, Massimo M; Colombo, Marika M
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35646638
Variant Present in the following documents:
  • Main text
  • fonc-12-889826.pdf
View BVdb publication page



Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.

Pathology Oncology Research : Por
Li, Lihong L; Song, Qianqian Q; Cao, Dandan D; Jiao, Yuchen Y; Yuan, Guangwen G; Song, Yan Y
Publication Date: 2022

Variant appearance in text: KRAS: 35G>A; Gly12Asp
PubMed Link: 35645619
Variant Present in the following documents:
  • DataSheet1.xlsx
View BVdb publication page



Chemotherapy Resistance in B-ALL with Cryptic NUP214-ABL1 Is Amenable to Kinase Inhibition and Immunotherapy.

The Oncologist
Nardi, Valentina V; McAfee, Steven L SL; Dal Cin, Paola P; Tsai, Harrison K HK; Amrein, Philip C PC; Hobbs, Gabriela S GS; Brunner, Andrew M AM; Narayan, Rupa R; Foster, Julia J; Fathi, Amir T AT; Hock, Hanno H
Publication Date: 2022-03-04

Variant appearance in text: KRAS: Gly12Asp
PubMed Link: 35641210
Variant Present in the following documents:
  • Main text
  • oyab052.pdf
View BVdb publication page



Endoscopic ultrasound guided interventions in the management of pancreatic cancer.

World Journal Of Gastrointestinal Endoscopy
Kerdsirichairat, Tossapol T; Shin, Eun Ji EJ
Publication Date: 2022-04-16

Variant appearance in text: KRAS: G12D
PubMed Link: 35634485
Variant Present in the following documents:
  • WJGE-14-191.pdf
View BVdb publication page



Molecular Signatures of KRAS-Mutated Lung Adenocarcinoma: Analysis of Concomitant EGFR, ALK, STK11, and PD-L1 Status.

Clinical Pathology (Thousand Oaks, Ventura County, Calif.)
Hsu, Jim J; Annunziata, Joseph F JF; Burns, Ethan E; Bernicker, Eric H EH; Olsen, Randall J RJ; Thomas, Jessica S JS
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35634237
Variant Present in the following documents:
  • Main text
  • 10.1177_2632010X221102054.pdf
View BVdb publication page



Virtual Screening Based on Machine Learning Explores Mangrove Natural Products as KRASG12C Inhibitors.

Pharmaceuticals (Basel, Switzerland)
Luo, Lianxiang L; Zheng, Tongyu T; Wang, Qu Q; Liao, Yingling Y; Zheng, Xiaoqi X; Zhong, Ai A; Huang, Zunnan Z; Luo, Hui H
Publication Date: 2022-05-08

Variant appearance in text: KRAS: G12D
PubMed Link: 35631410
Variant Present in the following documents:
  • Main text
  • pharmaceuticals-15-00584.pdf
View BVdb publication page



Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases MUTYH and hOGG1 in Colorectal Cancer Patients.

International Journal Of Molecular Sciences
Kavec, Miriam J MJ; Urbanova, Marketa M; Makovicky, Pavol P; Opattová, Alena A; Tomasova, Kristyna K; Kroupa, Michal M; Kostovcikova, Klara K; Siskova, Anna A; Navvabi, Nazila N; Schneiderova, Michaela M; Vymetalkova, Veronika V; Vodickova, Ludmila L; Vodicka, Pavel P
Publication Date: 2022-05-20

Variant appearance in text: KRAS: 35G>A
PubMed Link: 35628513
Variant Present in the following documents:
  • Main text
  • ijms-23-05704.pdf
View BVdb publication page



Basic Science with Preclinical Models to Investigate and Develop Liquid Biopsy: What Are the Available Data and Is It a Fruitful Approach?

International Journal Of Molecular Sciences
Cena, Benedetta B; Melloul, Emmanuel E; Demartines, Nicolas N; Dormond, Olivier O; Labgaa, Ismail I
Publication Date: 2022-05-10

Variant appearance in text: KRAS: G12D
PubMed Link: 35628154
Variant Present in the following documents:
  • ijms-23-05343.pdf
View BVdb publication page



Molecular Characterization of Pancreatic Ductal Adenocarcinoma Using a Next-Generation Sequencing Custom-Designed Multigene Panel.

Diagnostics (Basel, Switzerland)
Malvi, Deborah D; Vasuri, Francesco F; Maloberti, Thais T; Sanza, Viviana V; De Leo, Antonio A; Fornelli, Adele A; Masetti, Michele M; Benini, Claudia C; Lombardi, Raffaele R; Offi, Maria Fortuna MF; Di Marco, Mariacristina M; Ravaioli, Matteo M; Fiorino, Sirio S; Franceschi, Enrico E; Brandes, Alba A AA; Jovine, Elio E; D'Errico, Antonietta A; Tallini, Giovanni G; de Biase, Dario D
Publication Date: 2022-04-23

Variant appearance in text: KRAS: Gly12Asp
PubMed Link: 35626213
Variant Present in the following documents:
  • Main text
  • diagnostics-12-01058.pdf
View BVdb publication page



Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma: A Physiopathologic and Pharmacologic Review.

Cancers
Koltai, Tomas T; Reshkin, Stephan Joel SJ; Carvalho, Tiago M A TMA; Di Molfetta, Daria D; Greco, Maria Raffaella MR; Alfarouk, Khalid Omer KO; Cardone, Rosa Angela RA
Publication Date: 2022-05-18

Variant appearance in text: KRAS: G12D
PubMed Link: 35626089
Variant Present in the following documents:
  • Main text
View BVdb publication page



Colorectal Cancer Heterogeneity and the Impact on Precision Medicine and Therapy Efficacy.

Biomedicines
Rosati, Gerardo G; Aprile, Giuseppe G; Colombo, Alfredo A; Cordio, Stefano S; Giampaglia, Marianna M; Cappetta, Alessandro A; Porretto, Concetta Maria CM; De Stefano, Alfonso A; Bilancia, Domenico D; Avallone, Antonio A
Publication Date: 2022-04-30

Variant appearance in text: KRAS: G12D
PubMed Link: 35625772
Variant Present in the following documents:
  • Main text
  • biomedicines-10-01035.pdf
View BVdb publication page



KRAS/NRAS/BRAF Mutation Rate in Saudi Academic Hospital Patients With Colorectal Cancer.

Cureus
Saharti, Samah S
Publication Date: 2022-04

Variant appearance in text: KRAS: G12D
PubMed Link: 35619874
Variant Present in the following documents:
  • Main text
  • cureus-0014-00000024392.pdf
View BVdb publication page



New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming.

Journal Of Experimental & Clinical Cancer Research : Cr
Colyn, Leticia L; Alvarez-Sola, Gloria G; Latasa, M Ujue MU; Uriarte, Iker I; Herranz, Jose M JM; Arechederra, Maria M; Vlachogiannis, George G; Rae, Colin C; Pineda-Lucena, Antonio A; Casadei-Gardini, Andrea A; Pedica, Federica F; Aldrighetti, Luca L; López-López, Angeles A; López-Gonzálvez, Angeles A; Barbas, Coral C; Ciordia, Sergio S; Van Liempd, Sebastiaan M SM; Falcón-Pérez, Juan M JM; Urman, Jesus J; Sangro, Bruno B; Vicent, Silve S; Iraburu, Maria J MJ; Prosper, Felipe F; Nelson, Leonard J LJ; Banales, Jesus M JM; Martinez-Chantar, Maria Luz ML; Marin, Jose J G JJG; Braconi, Chiara C; Trautwein, Christian C; Corrales, Fernando J FJ; Cubero, F Javier FJ; Berasain, Carmen C; Fernandez-Barrena, Maite G MG; Avila, Matias A MA
Publication Date: 2022-05-26

Variant appearance in text: KRAS: G12D
PubMed Link: 35619118
Variant Present in the following documents:
  • Main text
  • 13046_2022_Article_2386.pdf
View BVdb publication page



Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-05-23

Variant appearance in text: KRAS: 35G>A; Gly12Asp
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.

Cell Death & Disease
Zheng, Zhen-Yuan ZY; Chu, Man-Yu MY; Lin, Wan W; Zheng, Ya-Qi YQ; Xu, Xiu-E XE; Chen, Yang Y; Liao, Lian-Di LD; Wu, Zhi-Yong ZY; Wang, Shao-Hong SH; Li, En-Min EM; Xu, Li-Yan LY
Publication Date: 2022-05-25

Variant appearance in text: KRAS: G12D
PubMed Link: 35614034
Variant Present in the following documents:
  • Main text
View BVdb publication page



p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.

Nature Communications
Solé, Laura L; Lobo-Jarne, Teresa T; Álvarez-Villanueva, Daniel D; Alonso-Marañón, Josune J; Guillén, Yolanda Y; Guix, Marta M; Sangrador, Irene I; Rozalén, Catalina C; Vert, Anna A; Barbachano, Antonio A; Lop, Joan J; Salido, Marta M; Bellosillo, Beatriz B; García-Romero, Raquel R; Garrido, Marta M; González, Jessica J; Martínez-Iniesta, María M; López-Arribillaga, Erika E; Salazar, Ramón R; Montagut, Clara C; Torres, Ferrán F; Iglesias, Mar M; Celià-Terrassa, Toni T; Muñoz, Alberto A; Villanueva, Alberto A; Bigas, Anna A; Espinosa, Lluís L
Publication Date: 2022-05-23

Variant appearance in text: KRAS: G12D
PubMed Link: 35606354
Variant Present in the following documents:
  • 41467_2022_30382_MOESM1_ESM.pdf
View BVdb publication page



The Current Landscape of mRNA Vaccines Against Viruses and Cancer-A Mini Review.

Frontiers In Immunology
Ladak, Reese Jalal RJ; He, Alexander J AJ; Huang, Yu-Hsun YH; Ding, Yu Y
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35603213
Variant Present in the following documents:
  • Main text
  • fimmu-13-885371.pdf
View BVdb publication page



Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis.

Communications Medicine
Berg, Hege F HF; Hjelmeland, Marta Espevold ME; Lien, Hilde H; Espedal, Heidi H; Fonnes, Tina T; Srivastava, Aashish A; Stokowy, Tomasz T; Strand, Elin E; Bozickovic, Olivera O; Stefansson, Ingunn M IM; Bjørge, Line L; Trovik, Jone J; Haldorsen, Ingfrid S IS; Hoivik, Erling A EA; Krakstad, Camilla C
Publication Date: 2021

Variant appearance in text: KRAS: G12D
PubMed Link: 35602206
Variant Present in the following documents:
  • 43856_2021_19_MOESM3_ESM.xlsx
View BVdb publication page



Recent Advances of Autophagy in Non-Small Cell Lung Cancer: From Basic Mechanisms to Clinical Application.

Frontiers In Oncology
Guo, Weina W; Du, Keye K; Luo, Shanshan S; Hu, Desheng D
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35600411
Variant Present in the following documents:
  • Main text
  • fonc-12-861959.pdf
View BVdb publication page



Worldwide Prevalence and Clinical Characteristics of RAS Mutations in Head and Neck Cancer: A Systematic Review and Meta-Analysis.

Frontiers In Oncology
Novoplansky, Ofra O; Jagadeeshan, Sankar S; Regev, Ohad O; Menashe, Idan I; Elkabets, Moshe M
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35600380
Variant Present in the following documents:
  • Main text
  • fonc-12-838911.pdf
View BVdb publication page



Pancreatic Organoids for Regenerative Medicine and Cancer Research.

Frontiers In Cell And Developmental Biology
Casamitjana, Joan J; Espinet, Elisa E; Rovira, Meritxell M
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35592251
Variant Present in the following documents:
  • Main text
View BVdb publication page



CSF3R T618I mutated chronic myelomonocytic leukemia: A proliferative subtype with a distinct mutational profile.

Leukemia Research Reports
Kwon, Adelaide A; Ibrahim, Ibrahim I; Le, Tri T; Jaso, Jesse Manuel JM; Weinberg, Olga O; Fuda, Franklin F; Chen, Weina W
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35586707
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Concomitant Kinase-Dead BRAF and Oncogenic KRAS Lead to an Aggressive Biologic Behavior and Tumor Lysis Syndrome: A Case Report.

Frontiers In Oncology
Holland, Roy R; Ben-Ishay, Offir O; Ben-Aharon, Irit I
Publication Date: 2022

Variant appearance in text: KRAS: 35G>A; G12D
PubMed Link: 35586494
Variant Present in the following documents:
  • fonc-12-885814.pdf
View BVdb publication page



Free Energy Profiles Relating With Conformational Transition of the Switch Domains Induced by G12 Mutations in GTP-Bound KRAS.

Frontiers In Molecular Biosciences
Chen, Jianzhong J; Zhang, Shaolong S; Zeng, Qingkai Q; Wang, Wei W; Zhang, Qinggang Q; Liu, Xinguo X
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35586192
Variant Present in the following documents:
  • fmolb-09-912518.pdf
View BVdb publication page



Results of screening in early and advanced thoracic malignancies in the EORTC pan-European SPECTAlung platform.

Scientific Reports
Morfouace, M M; Novello, S S; Stevovic, A A; Dooms, C C; Janžič, U U; Berghmans, T T; Dziadziuszko, R R; Gorlia, T T; Felip, E E; Paz-Ares, L L; Mazieres, J J; O'Brien, M M; Bironzo, P P; Vansteenkiste, J J; Lacroix, L L; Dingemans, A C AC; Golfinopoulos, V V; Besse, B B
Publication Date: 2022-05-18

Variant appearance in text: KRAS: G12D
PubMed Link: 35585228
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_12056.pdf
View BVdb publication page



Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma.

Cancer Drug Resistance (Alhambra, Calif.)
Alonso-Peña, Marta M; Sanchez-Martin, Anabel A; Sanchon-Sanchez, Paula P; Soto-Muñiz, Meraris M; Espinosa-Escudero, Ricardo R; Marin, Jose J G JJG
Publication Date: 2019

Variant appearance in text: KRAS: 35G>A; Gly12Asp
PubMed Link: 35582588
Variant Present in the following documents:
  • cdr-2-680.pdf
View BVdb publication page



Resistance to immune checkpoint inhibitors in KRAS-mutant non-small cell lung cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Li, Yunchang Y; Hu, Lanlin L; Peng, Xinhao X; Xu, Huasheng H; Tang, Bo B; Xu, Chuan C
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35582540
Variant Present in the following documents:
  • cdr-5-129.pdf
View BVdb publication page



Efficacy of ICIs on patients with oncogene-driven non-small cell lung cancer: a retrospective study.

Cancer Drug Resistance (Alhambra, Calif.)
Guo, Xiaojin X; Du, He H; Li, Jiayu J; Yang, Menghang M; Xiong, Anweng A; Zhang, Haiping H; Wu, Fengying F
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35582532
Variant Present in the following documents:
  • cdr-5-15.pdf
View BVdb publication page



The dark side of immunotherapy: pancreatic cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Mucciolo, Gianluca G; Roux, Cecilia C; Scagliotti, Alessandro A; Brugiapaglia, Silvia S; Novelli, Francesco F; Cappello, Paola P
Publication Date: 2020

Variant appearance in text: KRAS: G12D
PubMed Link: 35582441
Variant Present in the following documents:
  • cdr-3-491.pdf
View BVdb publication page



The implication of liquid biopsies to predict chemoresistance in pancreatic cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Pietri, Elisabetta E; Balsano, Rita R; Coriano, Matilde M; Gelsomino, Fabio F; Leonardi, Francesco F; Bui, Simona S; Gnetti, Letizia L; Valle, Raffaele Dalla RD; Garajová, Ingrid I
Publication Date: 2021

Variant appearance in text: KRAS: G12D
PubMed Link: 35582309
Variant Present in the following documents:
  • cdr-4-559.pdf
View BVdb publication page



Emerging RAS-directed therapies for cancer.

Cancer Drug Resistance (Alhambra, Calif.)
Conroy, Michael M; Cowzer, Darren D; Kolch, Walter W; Duffy, Austin G AG
Publication Date: 2021

Variant appearance in text: KRAS: G12D
PubMed Link: 35582302
Variant Present in the following documents:
  • cdr-4-543.pdf
View BVdb publication page



Drug resistance in cancer immunotherapy: new strategies to improve checkpoint inhibitor therapies.

Cancer Drug Resistance (Alhambra, Calif.)
Rodriguez-Pascual, Jesus J; Ayuso-Sacido, Angel A; Belda-Iniesta, Cristobal C
Publication Date: 2019

Variant appearance in text: KRAS: G12D
PubMed Link: 35582274
Variant Present in the following documents:
  • cdr-2-980.pdf
View BVdb publication page



Mutational landscape of normal epithelial cells in Lynch Syndrome patients.

Nature Communications
Lee, Bernard C H BCH; Robinson, Philip S PS; Coorens, Tim H H THH; Yan, Helen H N HHN; Olafsson, Sigurgeir S; Lee-Six, Henry H; Sanders, Mathijs A MA; Siu, Hoi Cheong HC; Hewinson, James J; Yue, Sarah S K SSK; Tsui, Wai Yin WY; Chan, Annie S Y ASY; Chan, Anthony K W AKW; Ho, Siu Lun SL; Campbell, Peter J PJ; Martincorena, Inigo I; Buczacki, Simon J A SJA; Yuen, Siu Tsan ST; Leung, Suet Yi SY; Stratton, Michael R MR
Publication Date: 2022-05-17

Variant appearance in text: KRAS: G12D
PubMed Link: 35581206
Variant Present in the following documents:
  • 41467_2022_29920_MOESM3_ESM.xlsx
View BVdb publication page



Neoadjuvant chemotherapy with or without radiotherapy versus upfront surgery for resectable pancreatic adenocarcinoma: a meta-analysis of randomized clinical trials.

Esmo Open
Ghanem, I I; Lora, D D; Herradón, N N; de Velasco, G G; Carretero-González, A A; Jiménez-Varas, M Á MÁ; Vázquez de Parga, P P; Feliu, J J
Publication Date: 2022-05-14

Variant appearance in text: KRAS: G12D
PubMed Link: 35580504
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer
Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X
Publication Date: 2022-05-16

Variant appearance in text: KRAS: 35G>A; G12D
PubMed Link: 35578198
Variant Present in the following documents:
  • 12885_2022_9602_MOESM9_ESM.xlsx
View BVdb publication page



The paradigm shift in treatment from Covid-19 to oncology with mRNA vaccines.

Cancer Treatment Reviews
Wei, Jiao J; Hui, Ai-Min AM
Publication Date: 2022-05-05

Variant appearance in text: KRAS: G12D
PubMed Link: 35576777
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Advances in the Study of Circadian Genes in Non-Small Cell Lung Cancer.

Integrative Cancer Therapies
Zhang, Hao H; Liu, Renwang R; Zhang, Bo B; Huo, Huandong H; Song, Zuoqing Z
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35575281
Variant Present in the following documents:
  • Main text
  • 10.1177_15347354221096080.pdf
View BVdb publication page



The Role and Mechanism of the Vascular Endothelial Niche in Diseases: A Review.

Frontiers In Physiology
Lei, Zhiqiang Z; Hu, Xiang X; Wu, Yaoqi Y; Fu, Longsheng L; Lai, Songqing S; Lin, Jing J; Li, Xiaobing X; Lv, Yanni Y
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35574466
Variant Present in the following documents:
  • fphys-13-863265.pdf
View BVdb publication page



Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma.

Frontiers In Oncology
Khadse, Anand A; Haakensen, Vilde D VD; Silwal-Pandit, Laxmi L; Hamfjord, Julian J; Micke, Patrick P; Botling, Johan J; Brustugun, Odd Terje OT; Lingjærde, Ole Christian OC; Helland, Åslaug Å; Kure, Elin H EH
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35574381
Variant Present in the following documents:
  • fonc-12-873532.pdf
View BVdb publication page



Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study.

Oncotarget
Sciortino, Carolina C; Viglialoro, Valentina V; Nucci, Massimo M; Polito, Mariam Grazia MG; Cortesi, Enrico E; Gelibter, Alain A; Gazzaniga, Paola P; Nicolazzo, Chiara C; Siringo, Marco M; Caponnetto, Salvatore S
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35574217
Variant Present in the following documents:
  • oncotarget-13-28230.pdf
View BVdb publication page



The Tumor Suppressor Kinase LKB1: Metabolic Nexus.

Frontiers In Cell And Developmental Biology
Bourouh, Mohammed M; Marignani, Paola A PA
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35573694
Variant Present in the following documents:
  • fcell-10-881297.pdf
View BVdb publication page



XNAs: A Troubleshooter for Nucleic Acid Sensing.

Acs Omega
Mana, Tanushree T; Bhattacharya, Budhaditya B; Lahiri, Hiya H; Mukhopadhyay, Rupa R
Publication Date: 2022-05-10

Variant appearance in text: KRAS: G12D
PubMed Link: 35571783
Variant Present in the following documents:
  • ao2c00581.pdf
View BVdb publication page



Endometrioid endometrial carcinoma of no-specific-molecular-profile with multiple bone metastases and muscle involvement: Case report and review of the literature.

Radiology Case Reports
Heidinger, Martin M; Koh, Mei M; Panzenboeck, Mario M; Lutz, Thomas T; Mertz, Kirsten D KD; Huemer, Hansjoerg H; Vetter, Marcus M; Brigitte, Frey Tirri FT
Publication Date: 2022-07

Variant appearance in text: KRAS: Gly12Asp
PubMed Link: 35570879
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures.

Cancers
Peindl, Matthias M; Göttlich, Claudia C; Crouch, Samantha S; Hoff, Niklas N; Lüttgens, Tamara T; Schmitt, Franziska F; Pereira, Jesús Guillermo Nieves JGN; May, Celina C; Schliermann, Anna A; Kronenthaler, Corinna C; Cheufou, Danjouma D; Reu-Hofer, Simone S; Rosenwald, Andreas A; Weigl, Elena E; Walles, Thorsten T; Schüler, Julia J; Dandekar, Thomas T; Nietzer, Sarah S; Dandekar, Gudrun G
Publication Date: 2022-04-27

Variant appearance in text: KRAS: G12D
PubMed Link: 35565305
Variant Present in the following documents:
  • cancers-14-02176.pdf
View BVdb publication page



Thymic Stromal Lymphopoietin Induction Suppresses Lung Cancer Development.

Cancers
Guennoun, Ranya R; Hojanazarova, Jennet J; Trerice, Kathryn E KE; Azin, Marjan M; McGoldrick, Matthew T MT; Schiferle, Erik B EB; Stover, Michael P MP; Demehri, Shadmehr S
Publication Date: 2022-04-27

Variant appearance in text: KRAS: G12D
PubMed Link: 35565302
Variant Present in the following documents:
  • cancers-14-02173.pdf
View BVdb publication page



Genetic and Clinical Characteristics of ARID1A Mutated Melanoma Reveal High Tumor Mutational Load without Implications on Patient Survival.

Cancers
Thielmann, Carl Maximilian CM; Matull, Johanna J; Roth, Sebastian S; Placke, Jan-Malte JM; Chorti, Eleftheria E; Zaremba, Anne A; Lodde, Georg G; Jansen, Philipp P; Krefting, Frederik F; Kretz, Julia J; Möller, Inga I; Sucker, Antje A; Paschen, Annette A; Livingstone, Elisabeth E; Zimmer, Lisa L; Ugurel, Selma S; Schadendorf, Dirk D; Hadaschik, Eva E; Griewank, Klaus G KG
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G12D
PubMed Link: 35565222
Variant Present in the following documents:
  • cancers-14-02090.pdf
View BVdb publication page



Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts.

Cancers
Go, Yoon-Ha YH; Choi, Woo Hee WH; Bae, Won Jung WJ; Jung, Sook-In SI; Cho, Chang-Hoon CH; Lee, Seung Ah SA; Park, Joon Seong JS; Ahn, Ji Mi JM; Kim, Sung Won SW; Lee, Kyung Jin KJ; Lee, Dakeun D; Yoo, Jongman J
Publication Date: 2022-04-21

Variant appearance in text: KRAS: G12D
PubMed Link: 35565206
Variant Present in the following documents:
  • cancers-14-02077.pdf
View BVdb publication page



KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer.

Cancers
Eklund, Ella A EA; Wiel, Clotilde C; Fagman, Henrik H; Akyürek, Levent M LM; Raghavan, Sukanya S; Nyman, Jan J; Hallqvist, Andreas A; Sayin, Volkan I VI
Publication Date: 2022-04-20

Variant appearance in text: KRAS: G12D
PubMed Link: 35565194
Variant Present in the following documents:
  • cancers-14-02063.pdf
View BVdb publication page



Obesity-Associated Cancers: Evidence from Studies in Mouse Models.

Cells
Lee, Ho H
Publication Date: 2022-04-27

Variant appearance in text: KRAS: G12D
PubMed Link: 35563777
Variant Present in the following documents:
  • cells-11-01472.pdf
View BVdb publication page



Prognostic and Immunotherapeutic Roles of KRAS in Pan-Cancer.

Cells
Yang, Kaixin K; Li, Chengyun C; Liu, Yang Y; Gu, Xueyan X; Jiang, Longchang L; Shi, Lei L
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G12D
PubMed Link: 35563733
Variant Present in the following documents:
  • cells-11-01427.pdf
View BVdb publication page



Single-Nucleotide Variations, Insertions/Deletions and Copy Number Variations in Myelodysplastic Syndrome during Disease Progression Revealed by a Single-Cell DNA Sequencing Platform.

International Journal Of Molecular Sciences
Lee, Paul P; Yim, Rita R; Fung, Sin-Hang SH; Miu, Kai-Kei KK; Wang, Zhangting Z; Wu, Ka-Chun KC; Au, Lester L; Leung, Garret Man-Kit GM; Lee, Victor Ho-Fun VH; Gill, Harinder H
Publication Date: 2022-04-22

Variant appearance in text: KRAS: G12D
PubMed Link: 35563039
Variant Present in the following documents:
  • ijms-23-04647.pdf
View BVdb publication page



PD-L1 Expression in Non-Small Cell Lung Cancer Specimens: Association with Clinicopathological Factors and Molecular Alterations.

International Journal Of Molecular Sciences
Mansour, Mohammed S I MSI; Malmros, Karina K; Mager, Ulrich U; Ericson Lindquist, Kajsa K; Hejny, Kim K; Holmgren, Benjamin B; Seidal, Tomas T; Dejmek, Annika A; Dobra, Katalin K; Planck, Maria M; Brunnström, Hans H
Publication Date: 2022-04-19

Variant appearance in text: KRAS: G12D
PubMed Link: 35562908
Variant Present in the following documents:
  • ijms-23-04517.pdf
View BVdb publication page



Differential expression analysis of genes and long non-coding RNAs associated with KRAS mutation in colorectal cancer cells.

Scientific Reports
Saliani, Mahsa M; Jalal, Razieh R; Javadmanesh, Ali A
Publication Date: 2022-05-13

Variant appearance in text: KRAS: G12D
PubMed Link: 35562390
Variant Present in the following documents:
  • 41598_2022_Article_11697.pdf
View BVdb publication page



Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ.

Nature Communications
Liu, Yi Y; Deguchi, Yasunori Y; Wei, Daoyan D; Liu, Fuyao F; Moussalli, Micheline J MJ; Deguchi, Eriko E; Li, Donghui D; Wang, Huamin H; Valentin, Lovie Ann LA; Colby, Jennifer K JK; Wang, Jing J; Zheng, Xiaofeng X; Ying, Haoqiang H; Gagea, Mihai M; Ji, Baoan B; Shi, Jiaqi J; Yao, James C JC; Zuo, Xiangsheng X; Shureiqi, Imad I
Publication Date: 2022-05-13

Variant appearance in text: KRAS: G12D
PubMed Link: 35562376
Variant Present in the following documents:
  • 41467_2022_Article_30392.pdf
View BVdb publication page



Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer.

Ebiomedicine
Jiang, Shu-Heng SH; Liu, Dejun D; Hu, Li-Peng LP; Zhang, Shan S; Yu, Yanqiu Y; Sun, Yong-Wei YW; Ji, Jianguang J; Zhang, Zhi-Gang ZG
Publication Date: 2022-05-10

Variant appearance in text: KRAS: G12D
PubMed Link: 35561453
Variant Present in the following documents:
  • Main text
View BVdb publication page



SNAT7 regulates mTORC1 via macropinocytosis.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Meng, Delong D; Yang, Qianmei Q; Jeong, Mi-Hyeon MH; Curukovic, Adna A; Tiwary, Shweta S; Melick, Chase H CH; Lama-Sherpa, Tshering D TD; Wang, Huanyu H; Huerta-Rosario, Mariela M; Urquhart, Greg G; Zacharias, Lauren G LG; Lewis, Cheryl C; DeBerardinis, Ralph J RJ; Jewell, Jenna L JL
Publication Date: 2022-05-17

Variant appearance in text: KRAS: G12D
PubMed Link: 35561222
Variant Present in the following documents:
  • pnas.202123261.pdf
  • pnas.2123261119.sapp.pdf
View BVdb publication page



Exosomes: Insights and therapeutic applications in cancer.

Translational Oncology
Panigrahi, Anita Raj AR; Srinivas, Lankalapalli L; Panda, Jagadeesh J
Publication Date: 2022-05-09

Variant appearance in text: KRAS: G12D
PubMed Link: 35551002
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

Nature Communications
Kim, Dae Gyu DG; Choi, Yongseok Y; Lee, Yuno Y; Lim, Semi S; Kong, Jiwon J; Song, JaeHa J; Roh, Younah Y; Harmalkar, Dipesh S DS; Lee, Kwanshik K; Goo, Ja-Il JI; Cho, Hye Young HY; Mushtaq, Ameeq Ul AU; Lee, Jihye J; Park, Song Hwa SH; Kim, Doyeun D; Min, Byung Soh BS; Lee, Kang Young KY; Jeon, Young Ho YH; Lee, Sunkyung S; Lee, Kyeong K; Kim, Sunghoon S
Publication Date: 2022-05-11

Variant appearance in text: KRAS: G12D
PubMed Link: 35546148
Variant Present in the following documents:
  • 41467_2022_30149_MOESM2_ESM.pdf
  • 41467_2022_30149_MOESM1_ESM.pdf
View BVdb publication page



Use of a highly sensitive lung cancer compact panel to detect KRAS G12D in the wash fluid from a lung tumor: A case report.

Thoracic Cancer
Minami, Daisuke D; Takigawa, Nagio N; Nakajima, Yasuhiro Y; Miyahara, Nobuaki N; Mizumori, Yasuyuki Y; Ueda, Mitsuhiro M; Nakamura, Seiji S; Suzuki, Fumihiko F; Sato, Yoshiharu Y; Morikawa, Kei K; Kanehiro, Arihiko A
Publication Date: 2022-05-12

Variant appearance in text: KRAS: G12D
PubMed Link: 35545933
Variant Present in the following documents:
  • Main text
  • TCA-13-1735.pdf
View BVdb publication page



Genetic Characteristics of Resectable Colorectal Cancer with Pulmonary Metastasis.

Canadian Journal Of Gastroenterology & Hepatology
Qiu, Yan-Yu YY; Peng, Dong D; Wei, Zheng-Qiang ZQ; Li, Jin-Dou JD; Huang, Yong-Jia YJ; Yang, Jian-Guo JG; Song, Zhi-Yang ZY; Cheng, Yong Y
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35531124
Variant Present in the following documents:
  • CJGH2022-2033876.pdf
View BVdb publication page



Comprehensive Molecular Profiling of Colorectal Cancer With Situs Inversus Totalis by Next-Generation Sequencing.

Frontiers In Oncology
Li, Hongsen H; Gong, Liu L; Cheng, Huanqing H; Wang, Huina H; Zhang, Xiaochen X; Rao, Chuangzhou C; Song, Zhangfa Z; Wang, Da D; Lou, Haizhou H; Lou, Feng F; Cao, Shanbo S; Pan, Hongming H; Fang, Yong Y
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35530355
Variant Present in the following documents:
  • fonc-12-813253.pdf
View BVdb publication page



Targeting Mutant Kirsten Rat Sarcoma Viral Oncogene Homolog in Non-Small Cell Lung Cancer: Current Difficulties, Integrative Treatments and Future Perspectives.

Frontiers In Pharmacology
Li, Jia-Xin JX; Li, Run-Ze RZ; Ma, Lin-Rui LR; Wang, Peng P; Xu, Dong-Han DH; Huang, Jie J; Li, Li-Qi LQ; Tang, Ling L; Xie, Ying Y; Leung, Elaine Lai-Han EL; Yan, Pei-Yu PY
Publication Date: 2022

Variant appearance in text: KRAS: G12D
PubMed Link: 35517800
Variant Present in the following documents:
  • fphar-13-875330.pdf
View BVdb publication page



CRISPR/Cas9 application in cancer therapy: a pioneering genome editing tool.

Cellular & Molecular Biology Letters
Shojaei Baghini, Sadegh S; Gardanova, Zhanna R ZR; Abadi, Saeme Azizi Hassan SAH; Zaman, Burhan Abdullah BA; İlhan, Ahmet A; Shomali, Navid N; Adili, Ali A; Moghaddar, Roozbeh R; Yaseri, Amirhossein Fakhre AF
Publication Date: 2022-05-04

Variant appearance in text: KRAS: 35G>A; G12D
PubMed Link: 35508982
Variant Present in the following documents:
  • 11658_2022_Article_336.pdf
View BVdb publication page



Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer
Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E
Publication Date: 2022-05-03

Variant appearance in text: KRAS: Gly12Asp; rs121913529
PubMed Link: 35505283
Variant Present in the following documents:
  • 12885_2022_9619_MOESM1_ESM.xlsx
View BVdb publication page



Efficacy of first-line immune checkpoint inhibitors in patients with advanced NSCLC with KRAS, MET, FGFR, RET, BRAF, and HER2 alterations.

Thoracic Cancer
Uehara, Yuji Y; Watanabe, Kageaki K; Hakozaki, Taiki T; Yomota, Makiko M; Hosomi, Yukio Y
Publication Date: 2022-05-02

Variant appearance in text: KRAS: G12D
PubMed Link: 35491960
Variant Present in the following documents:
  • TCA-13-1703.pdf
View BVdb publication page