Publications:

---

Comparative efficacy and safety of multitarget angiogenesis inhibitor combined with immune checkpoint inhibitor and nivolumab monotherapy as second-line or beyond for advanced lung adenocarcinoma in driver-negative patients: a retrospective comparative cohort study.

Translational Lung Cancer Research

Yu, Lian L; Xu, Jianlin J; Qiao, Rong R; Zhong, Hua H; Brueckl, Wolfgang M WM; Zhong, Runbo R

Publication Date: 2023-05-31

Variant appearance in text: KRAS: G12L

PubMed Link: 37323173

Variant Present in the following documents:

• tlcr-12-05-1108-supplementary.pdf

View BVdb publication page

---

Pathogenic genomic alterations in Chinese pancreatic cancer patients and their therapeutical implications.

Cancer Medicine

Zhao, Zhiming Z; Li, Xiaomo X; Wang, Fei F; Xu, Yong Y; Liu, Si S; Han, Quanli Q; Yang, Zhiying Z; Huang, Weiwei W; Yin, Zhuzeng Z; Liu, Qu Q; Tan, Haidong H; Ma, Tonghui T; Si, Shuang S; Huang, Jia J; Yuan, Hongling H; Li, Wei W; Liu, Rong R

Publication Date: 2023-03-31

Variant appearance in text: KRAS: G12L

PubMed Link: 36999792

Variant Present in the following documents:

• CAM4-12-11672.pdf

View BVdb publication page

---

Molecular Research in Pancreatic Cancer: Small Molecule Inhibitors, Their Mechanistic Pathways and Beyond.

Current Issues In Molecular Biology

Shetu, Shaila A SA; James, Nneoma N; Rivera, Gildardo G; Bandyopadhyay, Debasish D

Publication Date: 2023-02-27

Variant appearance in text: KRAS: G12L

PubMed Link: 36975494

Variant Present in the following documents:

• Main text
• cimb-45-00124.pdf

View BVdb publication page

---

KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences

Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN

Publication Date: 2023-03-02

Variant appearance in text: KRAS: G12L

PubMed Link: 36902296

Variant Present in the following documents:

• Main text
• ijms-24-04868.pdf

View BVdb publication page

---

Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.

Nature Communications

Werba, Gregor G; Weissinger, Daniel D; Kawaler, Emily A EA; Zhao, Ende E; Kalfakakou, Despoina D; Dhara, Surajit S; Wang, Lidong L; Lim, Heather B HB; Oh, Grace G; Jing, Xiaohong X; Beri, Nina N; Khanna, Lauren L; Gonda, Tamas T; Oberstein, Paul P; Hajdu, Cristina C; Loomis, Cynthia C; Heguy, Adriana A; Sherman, Mara H MH; Lund, Amanda W AW; Welling, Theodore H TH; Dolgalev, Igor I; Tsirigos, Aristotelis A; Simeone, Diane M DM

Publication Date: 2023-02-13

Variant appearance in text: KRAS: G12L

PubMed Link: 36781852

Variant Present in the following documents:

• 41467_2023_36296_MOESM3_ESM.xlsx, sheet 1
• 41467_2023_36296_MOESM4_ESM.pdf

View BVdb publication page

---

Maintenance therapy of low-dose nivolumab, S-1, and leucovorin in metastatic pancreatic adenocarcinoma with a germline mutation of MSH6: A case report.

Frontiers In Immunology

Peng, Shang-Hsuan SH; Chen, Bang-Bin BB; Kuo, Ting-Chun TC; Lee, Jen-Chieh JC; Yang, Shih-Hung SH

Publication Date: 2022

Variant appearance in text: KRAS: G12L

PubMed Link: 36582237

Variant Present in the following documents:

• Table_1.pdf

View BVdb publication page

---

Molecular characterization of acquired resistance to KRAS G12C-EGFR inhibition in colorectal cancer.

Cancer Discovery

Yaeger, Rona R; Mezzadra, Riccardo R; Sinopoli, Jenna J; Bian, Yu Y; Marasco, Michelangelo M; Kaplun, Esther E; Gao, Yijun Y; Zhao, HuiYong H; Da Cruz Paula, Arnaud A; Zhu, Yingjie Y; Chaves Perez, Almudena A; Chadalavada, Kalyani K; Tse, Edison E; Chowdhry, Sudhir S; Bowker, Sydney S; Chang, Qing Q; Qeriqi, Besnik B; Weigelt, Britta B; Nanjangud, Gouri J GJ; Berger, Michael F MF; Der-Torossian, Hirak H; Anderes, Kenna K; Socci, Nicholas D ND; Shia, Jinru J; Riely, Gregory J GJ; Murciano-Goroff, Yonina R YR; Li, Bob T BT; Christensen, James G JG; Reis-Filho, Jorge S JS; Solit, David B DB; de Stanchina, Elisa E; Lowe, Scott W SW; Rosen, Neal N; Misale, Sandra S

Publication Date: 2022-11-10

Variant appearance in text: KRAS: G12L

PubMed Link: 36355783

Variant Present in the following documents:

• 41.pdf

View BVdb publication page

---

NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Cell Reports

Ramakrishnan, Gopalakrishnan G; Parajuli, Parash P; Singh, Pura P; Friend, Creighton C; Hurwitz, Eric E; Prunier, Celine C; Razzaque, Mohammed S MS; Xu, Keli K; Atfi, Azeddine A

Publication Date: 2022-11-08

Variant appearance in text: KRAS: G12L

PubMed Link: 36351408

Variant Present in the following documents:

• NIHMS1848910-supplement-2.xlsx, sheet 1
• NIHMS1848910-supplement-2.xlsx, sheet 3

View BVdb publication page

---

Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.

Nature Communications

Kobayashi, Yoshihisa Y; Oxnard, Geoffrey R GR; Cohen, Elizabeth F EF; Mahadevan, Navin R NR; Alessi, Joao V JV; Hung, Yin P YP; Bertram, Arrien A AA; Heppner, David E DE; Ribeiro, Mauricio F MF; Sacardo, Karina P KP; Saddi, Rodrigo R; Macedo, Mariana P MP; Blasco, Rafael B RB; Li, Jiaqi J; Kurppa, Kari J KJ; Nguyen, Tom T; Voligny, Emma E; Ananda, Guruprasad G; Chiarle, Roberto R; Katz, Artur A; Tolstorukov, Michael Y MY; Sholl, Lynette M LM; Jänne, Pasi A PA

Publication Date: 2022-09-24

Variant appearance in text: KRAS: G12L

PubMed Link: 36153311

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: KRAS: G12L

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

---

Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.

Nature Communications

Bartolacci, Caterina C; Andreani, Cristina C; Vale, Gonçalo G; Berto, Stefano S; Melegari, Margherita M; Crouch, Anna Colleen AC; Baluya, Dodge L DL; Kemble, George G; Hodges, Kurt K; Starrett, Jacqueline J; Politi, Katerina K; Starnes, Sandra L SL; Lorenzini, Daniele D; Raso, Maria Gabriela MG; Solis Soto, Luisa M LM; Behrens, Carmen C; Kadara, Humam H; Gao, Boning B; Wistuba, Ignacio I II; Minna, John D JD; McDonald, Jeffrey G JG; Scaglioni, Pier Paolo PP

Publication Date: 2022-07-26

Variant appearance in text: KRAS: G12L

PubMed Link: 35882862

Variant Present in the following documents:

• 41467_2022_31963_MOESM11_ESM.xlsx, sheet 2

View BVdb publication page

---

Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.

Pathology Oncology Research : Por

Li, Lihong L; Song, Qianqian Q; Cao, Dandan D; Jiao, Yuchen Y; Yuan, Guangwen G; Song, Yan Y

Publication Date: 2022

Variant appearance in text: KRAS: G12L

PubMed Link: 35645619

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 3
• DataSheet1.xlsx, sheet 2

View BVdb publication page

---

Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies.

International Journal Of Molecular Sciences

Shetu, Shaila A SA; Bandyopadhyay, Debasish D

Publication Date: 2022-03-28

Variant appearance in text: KRAS: G12L

PubMed Link: 35409064

Variant Present in the following documents:

• Main text
• ijms-23-03706.pdf

View BVdb publication page

---

Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.

Jto Clinical And Research Reports

Thompson, Jeffrey C JC; Aggarwal, Charu C; Wong, Janeline J; Nimgaonkar, Vivek V; Hwang, Wei-Ting WT; Andronov, Michelle M; Dibardino, David M DM; Hutchinson, Christoph T CT; Ma, Kevin C KC; Lanfranco, Anthony A; Moon, Edmund E; Haas, Andrew R AR; Singh, Aditi P AP; Ciunci, Christine A CA; Marmarelis, Melina M; D'Avella, Christopher C; Cohen, Justine V JV; Bauml, Joshua M JM; Cohen, Roger B RB; Langer, Corey J CJ; Vachani, Anil A; Carpenter, Erica L EL

Publication Date: 2022-04

Variant appearance in text: KRAS: G12l

PubMed Link: 35392653

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

---

Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: G12L

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

---

The relationship between different subtypes of KRAS and PD-L1 & tumor mutation burden (TMB) based on next-generation sequencing (NGS) detection in Chinese lung cancer patients.

Translational Lung Cancer Research

Yang, Ying Y; Shen, Shengping S; Sun, Yingjia Y; Husain, Hatim H; Zhou, Haiyan H; Lu, Shun S; Li, Ziming Z

Publication Date: 2022-02

Variant appearance in text: KRAS: G12L

PubMed Link: 35280306

Variant Present in the following documents:

• Main text
• tlcr-11-02-213.pdf

View BVdb publication page

---

Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis.

Clinical Epigenetics

Kuang, Chaoyuan C; Park, Yongseok Y; Augustin, Ryan C RC; Lin, Yan Y; Hartman, Douglas J DJ; Seigh, Lindsey L; Pai, Reetesh K RK; Sun, Weijing W; Bahary, Nathan N; Ohr, James J; Rhee, John C JC; Marks, Stanley M SM; Beasley, H Scott HS; Shuai, Yongli Y; Herman, James G JG; Zarour, Hassane M HM; Chu, Edward E; Lee, James J JJ; Krishnamurthy, Anuradha A

Publication Date: 2022-01-06

Variant appearance in text: KRAS: G12L

PubMed Link: 34991708

Variant Present in the following documents:

• Main text
• 13148_2021_Article_1226.pdf

View BVdb publication page

---

Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis.

Clinical Epigenetics

Kuang, Chaoyuan C; Park, Yongseok Y; Augustin, Ryan C RC; Lin, Yan Y; Hartman, Douglas J DJ; Seigh, Lindsey L; Pai, Reetesh K RK; Sun, Weijing W; Bahary, Nathan N; Ohr, James J; Rhee, John C JC; Marks, Stanley M SM; Beasley, H Scott HS; Shuai, Yongli Y; Herman, James G JG; Zarour, Hassane M HM; Chu, Edward E; Lee, James J JJ; Krishnamurthy, Anuradha A

Publication Date: 2022-01-06

Variant appearance in text: KRAS: G12L

PubMed Link: 34991708

Variant Present in the following documents:

• Main text
• 13148_2021_Article_1226.pdf

View BVdb publication page

---

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KRAS: G12L

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

---

Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: KRAS: G12L

PubMed Link: 34440110

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Hacking Pancreatic Cancer: Present and Future of Personalized Medicine.

Pharmaceuticals (Basel, Switzerland)

Di Federico, Alessandro A; Tateo, Valentina V; Parisi, Claudia C; Formica, Francesca F; Carloni, Riccardo R; Frega, Giorgio G; Rizzo, Alessandro A; Ricci, Dalia D; Di Marco, Mariacristina M; Palloni, Andrea A; Brandi, Giovanni G

Publication Date: 2021-07-15

Variant appearance in text: KRAS: G12L

PubMed Link: 34358103

Variant Present in the following documents:

• Main text
• pharmaceuticals-14-00677.pdf

View BVdb publication page

---

The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine

Chang, Darwin D; Shain, A Hunter AH

Publication Date: 2021-07-16

Variant appearance in text: KRAS: G12L

PubMed Link: 34272401

Variant Present in the following documents:

• 41525_2021_226_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

GLI1: A Therapeutic Target for Cancer.

Frontiers In Oncology

Avery, Justin T JT; Zhang, Ruowen R; Boohaker, Rebecca J RJ

Publication Date: 2021

Variant appearance in text: KRAS: G12L

PubMed Link: 34113570

Variant Present in the following documents:

• Main text
• fonc-11-673154.pdf

View BVdb publication page

---

The origins and genetic interactions of KRAS mutations are allele- and tissue-specific.

Nature Communications

Cook, Joshua H JH; Melloni, Giorgio E M GEM; Gulhan, Doga C DC; Park, Peter J PJ; Haigis, Kevin M KM

Publication Date: 2021-03-22

Variant appearance in text: KRAS: G12L

PubMed Link: 33753749

Variant Present in the following documents:

• 41467_2021_22125_MOESM4_ESM.xlsx, sheet 4

View BVdb publication page

---

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: KRAS: G12L

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

---

Circulating Tumor DNA Detection by Digital-Droplet PCR in Pancreatic Ductal Adenocarcinoma: A Systematic Review.

Cancers

Huerta, Marisol M; Roselló, Susana S; Sabater, Luis L; Ferrer, Ana A; Tarazona, Noelia N; Roda, Desamparados D; Gambardella, Valentina V; Alfaro-Cervelló, Clara C; Garcés-Albir, Marina M; Cervantes, Andrés A; Ibarrola-Villava, Maider M

Publication Date: 2021-02-27

Variant appearance in text: KRAS: G12L

PubMed Link: 33673558

Variant Present in the following documents:

• Main text
• cancers-13-00994.pdf

View BVdb publication page

---

Accuracy of endoscopic ultrasound-guided needle aspiration specimens for molecular diagnosis of non-small-cell lung carcinoma.

World Journal Of Clinical Cases

Su, Wei W; Tian, Xiang-Dong XD; Liu, Peng P; Zhou, De-Jun DJ; Cao, Fu-Liang FL

Publication Date: 2020-11-06

Variant appearance in text: KRAS: G12L

PubMed Link: 33269250

Variant Present in the following documents:

• Main text
• WJCC-8-5139.pdf

View BVdb publication page

---

Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: KRAS: G12L

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

---

Promoter Methylation of Selected Genes in Non-Small-Cell Lung Cancer Patients and Cell Lines.

International Journal Of Molecular Sciences

Sarne, Victoria V; Huter, Samuel S; Braunmueller, Sandrina S; Rakob, Lisa L; Jacobi, Nico N; Kitzwögerer, Melitta M; Wiesner, Christoph C; Obrist, Peter P; Seeboeck, Rita R

Publication Date: 2020-06-28

Variant appearance in text: KRAS: G12L

PubMed Link: 32605217

Variant Present in the following documents:

• Main text
• ijms-21-04595.pdf

View BVdb publication page

---

Small Molecule KRAS Inhibitors: The Future for Targeted Pancreatic Cancer Therapy?

Cancers

Gillson, Josef J; Ramaswamy, Yogambha Y; Singh, Gurvinder G; Gorfe, Alemayehu A AA; Pavlakis, Nick N; Samra, Jaswinder J; Mittal, Anubhav A; Sahni, Sumit S

Publication Date: 2020-05-24

Variant appearance in text: KRAS: G12L

PubMed Link: 32456277

Variant Present in the following documents:

• Main text
• cancers-12-01341.pdf

View BVdb publication page

---

Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: KRAS: G12L

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

---

EGFR, KRAS, BRAF, ALK, and cMET genetic alterations in 1440 Sardinian patients with lung adenocarcinoma.

Bmc Pulmonary Medicine

Colombino, Maria M; Paliogiannis, Panagiotis P; Cossu, Antonio A; Santeufemia, Davide Adriano DA; , ; Sini, Maria Cristina MC; Casula, Milena M; Palomba, Grazia G; Manca, Antonella A; Pisano, Marina M; Doneddu, Valentina V; Palmieri, Giuseppe G

Publication Date: 2019-11-11

Variant appearance in text: KRAS: Gly12Leu

PubMed Link: 31711449

Variant Present in the following documents:

View BVdb publication page

---

Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm.

Oncogene

Raimondi, Francesco F; Inoue, Asuka A; Kadji, Francois M N FMN; Shuai, Ni N; Gonzalez, Juan-Carlos JC; Singh, Gurdeep G; de la Vega, Alicia Alonso AA; Sotillo, Rocio R; Fischer, Bernd B; Aoki, Junken J; Gutkind, J Silvio JS; Russell, Robert B RB

Publication Date: 2019-09

Variant appearance in text: KRAS: G12L

PubMed Link: 31337866

Variant Present in the following documents:

• 41388_2019_895_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

---

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma.

Nature Communications

Hu, Xin X; Fujimoto, Junya J; Ying, Lisha L; Fukuoka, Junya J; Ashizawa, Kazuto K; Sun, Wenyong W; Reuben, Alexandre A; Chow, Chi-Wan CW; McGranahan, Nicholas N; Chen, Runzhe R; Hu, Jinlin J; Godoy, Myrna C MC; Tabata, Kazuhiro K; Kuroda, Kishio K; Shi, Lei L; Li, Jun J; Behrens, Carmen C; Parra, Edwin Roger ER; Little, Latasha D LD; Gumbs, Curtis C; Mao, Xizeng X; Song, Xingzhi X; Tippen, Samantha S; Thornton, Rebecca L RL; Kadara, Humam H; Scheet, Paul P; Roarty, Emily E; Ostrin, Edwin Justin EJ; Wang, Xu X; Carter, Brett W BW; Antonoff, Mara B MB; Zhang, Jianhua J; Vaporciyan, Ara A AA; Pass, Harvey H; Swisher, Stephen G SG; Heymach, John V JV; Lee, J Jack JJ; Wistuba, Ignacio I II; Hong, Waun Ki WK; Futreal, P Andrew PA; Su, Dan D; Zhang, Jianjun J

Publication Date: 2019-07-05

Variant appearance in text: KRAS: G12L

PubMed Link: 31278276

Variant Present in the following documents:

• Main text
• 41467_2019_Article_10877.pdf
• 41467_2019_10877_MOESM4_ESM.xlsx, sheet 1
• 41467_2019_10877_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

---

Cell cycle plasticity driven by MTOR signaling: integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer.

Oncogene

Knudsen, Erik S ES; Kumarasamy, Vishnu V; Ruiz, Amanda A; Sivinski, Jared J; Chung, Sejin S; Grant, Adam A; Vail, Paris P; Chauhan, Shailender S SS; Jie, Tun T; Riall, Taylor S TS; Witkiewicz, Agnieszka K AK

Publication Date: 2019-05

Variant appearance in text: KRAS: G12L

PubMed Link: 30696953

Variant Present in the following documents:

• NIHMS1513108-supplement-1.pdf

View BVdb publication page

---

Genetic Alterations of Periampullary and Pancreatic Ductal Adenocarcinoma: An Overview.

Current Genomics

Sikdar, Nilabja N; Saha, Gourab G; Dutta, Ashmita A; Ghosh, Shibajyoti S; Shrikhande, Shailesh V SV; Banerjee, Sudeep S

Publication Date: 2018-09

Variant appearance in text: KRAS: G12L

PubMed Link: 30258276

Variant Present in the following documents:

• Main text
• CG-19-444.pdf

View BVdb publication page

---

Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors.

Scientific Reports

Mauro, Concetta Di CD; Pesapane, Ada A; Formisano, Luigi L; Rosa, Roberta R; D'Amato, Valentina V; Ciciola, Paola P; Servetto, Alberto A; Marciano, Roberta R; Orsini, Roberta Clara RC; Monteleone, Francesca F; Zambrano, Nicola N; Fontanini, Gabriella G; Servadio, Adele A; Pignataro, Giuseppe G; Grumetto, Lucia L; Lavecchia, Antonio A; Bruzzese, Dario D; Iaccarino, Antonino A; Troncone, Giancarlo G; Veneziani, Bianca Maria BM; Montuori, Nunzia N; Placido, Sabino De S; Bianco, Roberto R

Publication Date: 2017-08-24

Variant appearance in text: KRAS: G12L

PubMed Link: 28839232

Variant Present in the following documents:

• 41598_2017_10062_MOESM1_ESM.pdf

View BVdb publication page

---

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: KRAS: G12L

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

---

Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: KRAS: G12L

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

View BVdb publication page

---

Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types.

Scientific Reports

Shu, Yongqian Y; Wu, Xue X; Tong, Xiaoling X; Wang, Xiaonan X; Chang, Zhili Z; Mao, Yu Y; Chen, Xiaofeng X; Sun, Jing J; Wang, Zhenxin Z; Hong, Zhuan Z; Zhu, Liangjun L; Zhu, Chunrong C; Chen, Jun J; Liang, Ying Y; Shao, Huawu H; Shao, Yang W YW

Publication Date: 2017-04-03

Variant appearance in text: KRAS: G12L

PubMed Link: 28373672

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: KRAS: G12L

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

View BVdb publication page

---

Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis.

Plos Medicine

Sivakumar, Shivan S; de Santiago, Ines I; Chlon, Leon L; Markowetz, Florian F

Publication Date: 2017-01

Variant appearance in text: KRAS: G12L

PubMed Link: 28141826

Variant Present in the following documents:

• Main text
• pmed.1002223.pdf

View BVdb publication page

---

Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Weisman, Paul S PS; Ng, Charlotte K Y CK; Brogi, Edi E; Eisenberg, Rachel E RE; Won, Helen H HH; Piscuoglio, Salvatore S; De Filippo, Maria R MR; Ioris, Rafael R; Akram, Muzaffar M; Norton, Larry L; Weigelt, Britta B; Berger, Michael F MF; Reis-Filho, Jorge S JS; Wen, Hannah Y HY

Publication Date: 2016-05

Variant appearance in text: KRAS: G12L

PubMed Link: 26939876

Variant Present in the following documents:

• NIHMS752475-supplement-3.xlsx, sheet 1

View BVdb publication page

---

Reliable Detection of Somatic Mutations in Fine Needle Aspirates of Pancreatic Cancer With Next-generation Sequencing: Implications for Surgical Management.

Annals Of Surgery

Valero, Vicente V; Saunders, Tyler J TJ; He, Jin J; Weiss, Matthew J MJ; Cameron, John L JL; Dholakia, Avani A; Wild, Aaron T AT; Shin, Eun Ji EJ; Khashab, Mouen A MA; O'Broin-Lennon, Anne Marie AM; Ali, Syed Z SZ; Laheru, Daniel D; Hruban, Ralph H RH; Iacobuzio-Donahue, Christine A CA; Herman, Joseph M JM; Wolfgang, Christopher L CL

Publication Date: 2016-01

Variant appearance in text: KRAS: G12L

PubMed Link: 26020105

Variant Present in the following documents:

• Main text

View BVdb publication page

---

BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

British Journal Of Cancer

Schirripa, M M; Bergamo, F F; Cremolini, C C; Casagrande, M M; Lonardi, S S; Aprile, G G; Yang, D D; Marmorino, F F; Pasquini, G G; Sensi, E E; Lupi, C C; De Maglio, G G; Borrelli, N N; Pizzolitto, S S; Fasola, G G; Bertorelle, R R; Rugge, M M; Fontanini, G G; Zagonel, V V; Loupakis, F F; Falcone, A A

Publication Date: 2015-06-09

Variant appearance in text: KRAS: G12L

PubMed Link: 25942399

Variant Present in the following documents:

View BVdb publication page

---

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Nature Communications

Witkiewicz, Agnieszka K AK; McMillan, Elizabeth A EA; Balaji, Uthra U; Baek, GuemHee G; Lin, Wan-Chi WC; Mansour, John J; Mollaee, Mehri M; Wagner, Kay-Uwe KU; Koduru, Prasad P; Yopp, Adam A; Choti, Michael A MA; Yeo, Charles J CJ; McCue, Peter P; White, Michael A MA; Knudsen, Erik S ES

Publication Date: 2015-04-09

Variant appearance in text: KRAS: G12L

PubMed Link: 25855536

Variant Present in the following documents:

• ncomms7744-s2.xlsx, sheet 1

View BVdb publication page

---

Identification of candidate genes for lung cancer somatic mutation test kits.

Genetics And Molecular Biology

Chen, Yong Y; Shi, Jian-Xin JX; Pan, Xu-Feng XF; Feng, Jian J; Zhao, Heng H

Publication Date: 2013-09

Variant appearance in text: KRAS: G12L

PubMed Link: 24130455

Variant Present in the following documents:

• Main text

View BVdb publication page

---

KRAS mutational analysis and immunohistochemical studies can help distinguish pancreatic metastases from primary lung adenocarcinomas.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Krasinskas, Alyssa M AM; Chiosea, Simon I SI; Pal, Timothy T; Dacic, Sanja S

Publication Date: 2014-02

Variant appearance in text: KRAS: G12L

PubMed Link: 23887294

Variant Present in the following documents:

• Main text

View BVdb publication page

---

KRAS mutations and subtyping in colorectal cancer in Jordanian patients.

Oncology Letters

Elbjeirami, Wafa M WM; Sughayer, Maher A MA

Publication Date: 2012-10

Variant appearance in text: KRAS: Gly12Leu

PubMed Link: 23205087

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The introduction of systematic genomic testing for patients with non-small-cell lung cancer.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Cardarella, Stephanie S; Ortiz, Taylor M TM; Joshi, Victoria A VA; Butaney, Mohit M; Jackman, David M DM; Kwiatkowski, David J DJ; Yeap, Beow Y BY; Jänne, Pasi A PA; Lindeman, Neal I NI; Johnson, Bruce E BE

Publication Date: 2012-12

Variant appearance in text: KRAS: G12L

PubMed Link: 23154547

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.

The American Journal Of Surgical Pathology

Yachida, Shinichi S; Vakiani, Efsevia E; White, Catherine M CM; Zhong, Yi Y; Saunders, Tyler T; Morgan, Richard R; de Wilde, Roeland F RF; Maitra, Anirban A; Hicks, Jessica J; Demarzo, Angelo M AM; Shi, Chanjuan C; Sharma, Rajni R; Laheru, Daniel D; Edil, Barish H BH; Wolfgang, Christopher L CL; Schulick, Richard D RD; Hruban, Ralph H RH; Tang, Laura H LH; Klimstra, David S DS; Iacobuzio-Donahue, Christine A CA

Publication Date: 2012-02

Variant appearance in text: KRAS: G12L

PubMed Link: 22251937

Variant Present in the following documents:

• Main text

View BVdb publication page

---

SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.

The Journal Of Molecular Diagnostics : Jmd

Fariña Sarasqueta, Arantza A; Moerland, Elna E; de Bruyne, Hanneke H; de Graaf, Henk H; Vrancken, Tamara T; van Lijnschoten, Gesina G; van den Brule, Adriaan J C AJ

Publication Date: 2011-03

Variant appearance in text: KRAS: Gly12Leu

PubMed Link: 21354055

Variant Present in the following documents:

• Main text

View BVdb publication page

---