Publications:

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: KRAS: G12I

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

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Characteristics and Treatment Outcomes in Advanced-Stage Non-Small Cell Lung Cancer Patients with a KRAS G12C Mutation: A Real-World Study.

Journal Of Clinical Medicine

Illini, Oliver O; Fabikan, Hannah H; Hochmair, Maximilian Johannes MJ; Weinlinger, Christoph C; Krenbek, Dagmar D; Brcic, Luka L; Setinek, Ulrike U; Terbuch, Angelika A; Absenger, Gudrun G; Konjić, Selma S; Valipour, Arschang A

Publication Date: 2022-07-15

Variant appearance in text: KRAS: G12I

PubMed Link: 35887862

Variant Present in the following documents:

• jcm-11-04098.pdf

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Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.

Pathology Oncology Research : Por

Li, Lihong L; Song, Qianqian Q; Cao, Dandan D; Jiao, Yuchen Y; Yuan, Guangwen G; Song, Yan Y

Publication Date: 2022

Variant appearance in text: KRAS: G12I

PubMed Link: 35645619

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 2
• DataSheet1.xlsx, sheet 3

View BVdb publication page

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Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.

Jto Clinical And Research Reports

Thompson, Jeffrey C JC; Aggarwal, Charu C; Wong, Janeline J; Nimgaonkar, Vivek V; Hwang, Wei-Ting WT; Andronov, Michelle M; Dibardino, David M DM; Hutchinson, Christoph T CT; Ma, Kevin C KC; Lanfranco, Anthony A; Moon, Edmund E; Haas, Andrew R AR; Singh, Aditi P AP; Ciunci, Christine A CA; Marmarelis, Melina M; D'Avella, Christopher C; Cohen, Justine V JV; Bauml, Joshua M JM; Cohen, Roger B RB; Langer, Corey J CJ; Vachani, Anil A; Carpenter, Erica L EL

Publication Date: 2022-04

Variant appearance in text: KRAS: G12I

PubMed Link: 35392653

Variant Present in the following documents:

• mmc2.pdf

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: G12I

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

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A Cross-Sectional Study for Evaluation of KRAS and BRAF Mutations by Reverse Dot Blot, PCR-RFLP, and Allele-Specific PCR Methods Among Patients with Colorectal Cancer.

Avicenna Journal Of Medical Biotechnology

Sheikhsofla, Fatemeh F; Poopak, Behzad B; Firuzyar, Sajjad S; Roudbari, Fatemeh F; Ghadiany, Mojtaba M

Publication Date: 2021

Variant appearance in text: KRAS: G12I

PubMed Link: 34900144

Variant Present in the following documents:

• Main text
• AJMB-13-183.pdf

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The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine

Chang, Darwin D; Shain, A Hunter AH

Publication Date: 2021-07-16

Variant appearance in text: KRAS: G12I

PubMed Link: 34272401

Variant Present in the following documents:

• 41525_2021_226_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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The origins and genetic interactions of KRAS mutations are allele- and tissue-specific.

Nature Communications

Cook, Joshua H JH; Melloni, Giorgio E M GEM; Gulhan, Doga C DC; Park, Peter J PJ; Haigis, Kevin M KM

Publication Date: 2021-03-22

Variant appearance in text: KRAS: G12I

PubMed Link: 33753749

Variant Present in the following documents:

• 41467_2021_22125_MOESM4_ESM.xlsx, sheet 4

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: KRAS: G12I

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: KRAS: 34_35delGGinsAT; G12I

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Blood-based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Pancreatic Cancer and its Value to Guide Clinical Treatment.

Journal Of Cancer

Li, Hengchao H; Di, Yang Y; Li, Ji J; Jiang, Yongjian Y; He, Hang H; Yao, Lie L; Gu, Jichun J; Lu, Jiajun J; Song, Jia J; Chen, Shiqing S; Cai, Shangli S; Jin, Chen C; Yuan, Zhou Z; Fu, Deliang D

Publication Date: 2020

Variant appearance in text: KRAS: G12I

PubMed Link: 32489450

Variant Present in the following documents:

• Main text
• jcav11p4316.pdf

View BVdb publication page

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Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: KRAS: G12I

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

View BVdb publication page

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Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm.

Oncogene

Raimondi, Francesco F; Inoue, Asuka A; Kadji, Francois M N FMN; Shuai, Ni N; Gonzalez, Juan-Carlos JC; Singh, Gurdeep G; de la Vega, Alicia Alonso AA; Sotillo, Rocio R; Fischer, Bernd B; Aoki, Junken J; Gutkind, J Silvio JS; Russell, Robert B RB

Publication Date: 2019-09

Variant appearance in text: KRAS: G12I

PubMed Link: 31337866

Variant Present in the following documents:

• 41388_2019_895_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

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Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer.

Journal Of Translational Medicine

Isnaldi, Edoardo E; Garuti, Anna A; Cirmena, Gabriella G; Scabini, Stefano S; Rimini, Edoardo E; Ferrando, Lorenzo L; Lia, Michela M; Murialdo, Roberto R; Tixi, Lucia L; Carminati, Enrico E; Panaro, Andrea A; Gallo, Maurizio M; Grillo, Federica F; Mastracci, Luca L; Repetto, Lazzaro L; Fiocca, Roberto R; Romairone, Emanuele E; Zoppoli, Gabriele G; Ballestrero, Alberto A

Publication Date: 2019-04-29

Variant appearance in text: KRAS: G12I

PubMed Link: 31036005

Variant Present in the following documents:

• Main text
• 12967_2019_Article_1879.pdf

View BVdb publication page

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Precision medicine review: rare driver mutations and their biophysical classification.

Biophysical Reviews

Nussinov, Ruth R; Jang, Hyunbum H; Tsai, Chung-Jung CJ; Cheng, Feixiong F

Publication Date: 2019-02

Variant appearance in text: KRAS: G12I

PubMed Link: 30610579

Variant Present in the following documents:

• Main text
• 12551_2018_Article_496.pdf

View BVdb publication page

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Comprehensive Validation of Snapback Primer-Based Melting Curve Analysis to Detect Nucleotide Variation in the Codon 12 and 13 of KRAS Gene.

Biomed Research International

Zhang, Qunfeng Q; Du, Yiqiao Y; Zhang, Xinju X; Kang, Zhihua Z; Guan, Ming M; Wu, Zhiyuan Z

Publication Date: 2018

Variant appearance in text: KRAS: G12I

PubMed Link: 30406144

Variant Present in the following documents:

• Main text

View BVdb publication page

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Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience.

Bmc Cancer

Glassman, Danielle C DC; Palmaira, Randze L RL; Covington, Christina M CM; Desai, Avni M AM; Ku, Geoffrey Y GY; Li, Jia J; Harding, James J JJ; Varghese, Anna M AM; O'Reilly, Eileen M EM; Yu, Kenneth H KH

Publication Date: 2018-06-27

Variant appearance in text: KRAS: G12I

PubMed Link: 29945562

Variant Present in the following documents:

• 12885_2018_4605_MOESM1_ESM.pdf

View BVdb publication page

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Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia.

Gut

Singhi, Aatur D AD; McGrath, Kevin K; Brand, Randall E RE; Khalid, Asif A; Zeh, Herbert J HJ; Chennat, Jennifer S JS; Fasanella, Kenneth E KE; Papachristou, Georgios I GI; Slivka, Adam A; Bartlett, David L DL; Dasyam, Anil K AK; Hogg, Melissa M; Lee, Kenneth K KK; Marsh, James Wallis JW; Monaco, Sara E SE; Ohori, N Paul NP; Pingpank, James F JF; Tsung, Allan A; Zureikat, Amer H AH; Wald, Abigail I AI; Nikiforova, Marina N MN

Publication Date: 2018-12

Variant appearance in text: KRAS: G12I

PubMed Link: 28970292

Variant Present in the following documents:

• gutjnl-2016-313586supp002.pdf

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: KRAS: G12I

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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SensiScreen®KRAS exon 2-sensitive simplex and multiplex real-time PCR-based assays for detection of KRAS exon 2 mutations.

Plos One

Riva, Alice A; BØrgesen, Michael M; Guldmann-Christensen, Mariann M; Hauge Kyneb, Majbritt M; Voogd, Kirsten K; Andersen, Christina C; Epistolio, Samantha S; Merlo, Elisabetta E; Yding Wolff, Tine T; Hamilton-Dutoit, Stephen S; Lorenzen, Jan J; Christensen, Ulf Bech UB; Frattini, Milo M

Publication Date: 2017

Variant appearance in text: KRAS: G12I

PubMed Link: 28636636

Variant Present in the following documents:

• Main text
• pone.0178027.pdf

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: KRAS: G12I

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

View BVdb publication page

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: KRAS: G12I

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

View BVdb publication page

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Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Weisman, Paul S PS; Ng, Charlotte K Y CK; Brogi, Edi E; Eisenberg, Rachel E RE; Won, Helen H HH; Piscuoglio, Salvatore S; De Filippo, Maria R MR; Ioris, Rafael R; Akram, Muzaffar M; Norton, Larry L; Weigelt, Britta B; Berger, Michael F MF; Reis-Filho, Jorge S JS; Wen, Hannah Y HY

Publication Date: 2016-05

Variant appearance in text: KRAS: G12I

PubMed Link: 26939876

Variant Present in the following documents:

• NIHMS752475-supplement-3.xlsx, sheet 1

View BVdb publication page

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Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.

Nature Genetics

Krauthammer, Michael M; Kong, Yong Y; Bacchiocchi, Antonella A; Evans, Perry P; Pornputtapong, Natapol N; Wu, Cen C; McCusker, James P JP; Ma, Shuangge S; Cheng, Elaine E; Straub, Robert R; Serin, Merdan M; Bosenberg, Marcus M; Ariyan, Stephan S; Narayan, Deepak D; Sznol, Mario M; Kluger, Harriet M HM; Mane, Shrikant S; Schlessinger, Joseph J; Lifton, Richard P RP; Halaban, Ruth R

Publication Date: 2015-09

Variant appearance in text: KRAS: G12I

PubMed Link: 26214590

Variant Present in the following documents:

• Main text

View BVdb publication page

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BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

British Journal Of Cancer

Schirripa, M M; Bergamo, F F; Cremolini, C C; Casagrande, M M; Lonardi, S S; Aprile, G G; Yang, D D; Marmorino, F F; Pasquini, G G; Sensi, E E; Lupi, C C; De Maglio, G G; Borrelli, N N; Pizzolitto, S S; Fasola, G G; Bertorelle, R R; Rugge, M M; Fontanini, G G; Zagonel, V V; Loupakis, F F; Falcone, A A

Publication Date: 2015-06-09

Variant appearance in text: KRAS: G12I

PubMed Link: 25942399

Variant Present in the following documents:

View BVdb publication page

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Nature Communications

Witkiewicz, Agnieszka K AK; McMillan, Elizabeth A EA; Balaji, Uthra U; Baek, GuemHee G; Lin, Wan-Chi WC; Mansour, John J; Mollaee, Mehri M; Wagner, Kay-Uwe KU; Koduru, Prasad P; Yopp, Adam A; Choti, Michael A MA; Yeo, Charles J CJ; McCue, Peter P; White, Michael A MA; Knudsen, Erik S ES

Publication Date: 2015-04-09

Variant appearance in text: KRAS: G12I

PubMed Link: 25855536

Variant Present in the following documents:

• ncomms7744-s2.xlsx, sheet 1

View BVdb publication page

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Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.

Nature Communications

Schulz, Eduard E; Klampfl, Petra P; Holzapfel, Stefanie S; Janecke, Andreas R AR; Ulz, Peter P; Renner, Wilfried W; Kashofer, Karl K; Nojima, Satoshi S; Leitner, Anita A; Zebisch, Armin A; Wölfler, Albert A; Hofer, Sybille S; Gerger, Armin A; Lax, Sigurd S; Beham-Schmid, Christine C; Steinke, Verena V; Heitzer, Ellen E; Geigl, Jochen B JB; Windpassinger, Christian C; Hoefler, Gerald G; Speicher, Michael R MR; Boland, C Richard CR; Kumanogoh, Atsushi A; Sill, Heinz H

Publication Date: 2014-10-13

Variant appearance in text: KRAS: 34_35delinsAT; G12I

PubMed Link: 25307848

Variant Present in the following documents:

• Main text
• ncomms6191.pdf

View BVdb publication page

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KRAS mutations and subtyping in colorectal cancer in Jordanian patients.

Oncology Letters

Elbjeirami, Wafa M WM; Sughayer, Maher A MA

Publication Date: 2012-10

Variant appearance in text: KRAS: Gly12Ile

PubMed Link: 23205087

Variant Present in the following documents:

• Main text

View BVdb publication page

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SNaPshot and StripAssay as valuable alternatives to direct sequencing for KRAS mutation detection in colon cancer routine diagnostics.

The Journal Of Molecular Diagnostics : Jmd

Fariña Sarasqueta, Arantza A; Moerland, Elna E; de Bruyne, Hanneke H; de Graaf, Henk H; Vrancken, Tamara T; van Lijnschoten, Gesina G; van den Brule, Adriaan J C AJ

Publication Date: 2011-03

Variant appearance in text: KRAS: Gly12Ile

PubMed Link: 21354055

Variant Present in the following documents:

• Main text

View BVdb publication page

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Detection of KRAS and BRAF mutations in colorectal carcinoma roles for high-sensitivity locked nucleic acid-PCR sequencing and broad-spectrum mass spectrometry genotyping.

The Journal Of Molecular Diagnostics : Jmd

Arcila, Maria M; Lau, Christopher C; Nafa, Khedoudja K; Ladanyi, Marc M

Publication Date: 2011-01

Variant appearance in text: KRAS: G12I

PubMed Link: 21227396

Variant Present in the following documents:

• Main text

View BVdb publication page

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