KRAS c.31G>A ;(p.A11T)

Variant ID: 12-25398288-C-T

NM_004985.3(KRAS):c.31G>A;(p.A11T)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences
Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN
Publication Date: 2023-03-02

Variant appearance in text: KRAS: A11T
PubMed Link: 36902296
Variant Present in the following documents:
  • ijms-24-04868.pdf
View BVdb publication page



Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer.

Nature Genetics
Cui Zhou, Daniel D; Jayasinghe, Reyka G RG; Chen, Siqi S; Herndon, John M JM; Iglesia, Michael D MD; Navale, Pooja P; Wendl, Michael C MC; Caravan, Wagma W; Sato, Kazuhito K; Storrs, Erik E; Mo, Chia-Kuei CK; Liu, Jingxian J; Southard-Smith, Austin N AN; Wu, Yige Y; Naser Al Deen, Nataly N; Baer, John M JM; Fulton, Robert S RS; Wyczalkowski, Matthew A MA; Liu, Ruiyang R; Fronick, Catrina C CC; Fulton, Lucinda A LA; Shinkle, Andrew A; Thammavong, Lisa L; Zhu, Houxiang H; Sun, Hua H; Wang, Liang-Bo LB; Li, Yize Y; Zuo, Chong C; McMichael, Joshua F JF; Davies, Sherri R SR; Appelbaum, Elizabeth L EL; Robbins, Keenan J KJ; Chasnoff, Sara E SE; Yang, Xiaolu X; Reeb, Ashley N AN; Oh, Clara C; Serasanambati, Mamatha M; Lal, Preet P; Varghese, Rajees R; Mashl, Jay R JR; Ponce, Jennifer J; Terekhanova, Nadezhda V NV; Yao, Lijun L; Wang, Fang F; Chen, Lijun L; Schnaubelt, Michael M; Lu, Rita Jui-Hsien RJ; Schwarz, Julie K JK; Puram, Sidharth V SV; Kim, Albert H AH; Song, Sheng-Kwei SK; Shoghi, Kooresh I KI; Lau, Ken S KS; Ju, Tao T; Chen, Ken K; Chatterjee, Deyali D; Hawkins, William G WG; Zhang, Hui H; Achilefu, Samuel S; Chheda, Milan G MG; Oh, Stephen T ST; Gillanders, William E WE; Chen, Feng F; DeNardo, David G DG; Fields, Ryan C RC; Ding, Li L
Publication Date: 2022-09

Variant appearance in text: KRAS: Ala11Thr
PubMed Link: 35995947
Variant Present in the following documents:
  • 41588_2022_1157_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page



Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies.

Peerj
Prieto-Potin, Iván I; Carvajal, Nerea N; Plaza-Sánchez, Jenifer J; Manso, Rebeca R; Aúz-Alexandre, Carmen Laura CL; Chamizo, Cristina C; Zazo, Sandra S; López-Sánchez, Almudena A; Rodríguez-Pinilla, Socorro María SM; Camacho, Laura L; Longarón, Raquel R; Bellosillo, Beatriz B; Somoza, Rosa R; Hernández-Losa, Javier J; Fernández-Soria, Víctor Manuel VM; Ramos-Ruiz, Ricardo R; Cristóbal, Ion I; García-Foncillas, Jesús J; Rojo, Federico F
Publication Date: 2020

Variant appearance in text: KRAS: 31G>A; Ala11Thr
PubMed Link: 33083132
Variant Present in the following documents:
  • peerj-08-10069-s010.xlsx, sheet 1
  • peerj-08-10069-s012.xlsx, sheet 1
  • peerj-08-10069-s013.xlsx, sheet 1
  • peerj-08-10069-s009.xlsx, sheet 1
View BVdb publication page



Reassessing the role of high dose cytarabine and mitoxantrone in relapsed/refractory acute myeloid leukemia.

Oncotarget
Canaani, Jonathan J; Nagar, Meital M; Heering, Gabriel G; Gefen, Chen C; Yerushalmi, Ronit R; Shem-Tov, Noga N; Volchek, Yulia Y; Merkel, Drorit D; Avigdor, Abraham A; Shimoni, Avichai A; Amariglio, Ninette N; Rechavi, Gidi G; Nagler, Arnon A
Publication Date: 2020-06-09

Variant appearance in text: KRAS: A11T
PubMed Link: 32577167
Variant Present in the following documents:
  • Main text
  • oncotarget-11-2233.pdf
View BVdb publication page



Immunophenotypes of pancreatic ductal adenocarcinoma: Meta-analysis of transcriptional subtypes.

International Journal Of Cancer
de Santiago, Ines I; Yau, Christopher C; Heij, Lara L; Middleton, Mark R MR; Markowetz, Florian F; Grabsch, Heike I HI; Dustin, Michael L ML; Sivakumar, Shivan S
Publication Date: 2019-08-15

Variant appearance in text: KRAS: A11T
PubMed Link: 30720864
Variant Present in the following documents:
  • Main text
  • IJC-145-1125.pdf
View BVdb publication page



Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.

Nature Communications
Russo, Mariangela M; Lamba, Simona S; Lorenzato, Annalisa A; Sogari, Alberto A; Corti, Giorgio G; Rospo, Giuseppe G; Mussolin, Benedetta B; Montone, Monica M; Lazzari, Luca L; Arena, Sabrina S; Oddo, Daniele D; Linnebacher, Michael M; Sartore-Bianchi, Andrea A; Pietrantonio, Filippo F; Siena, Salvatore S; Di Nicolantonio, Federica F; Bardelli, Alberto A
Publication Date: 2018-06-12

Variant appearance in text: KRAS: A11T
PubMed Link: 29895949
Variant Present in the following documents:
  • 41467_2018_4506_MOESM2_ESM.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: A11T
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Survival of pancreatic cancer cells lacking KRAS function.

Nature Communications
Muzumdar, Mandar Deepak MD; Chen, Pan-Yu PY; Dorans, Kimberly Judith KJ; Chung, Katherine Minjee KM; Bhutkar, Arjun A; Hong, Erin E; Noll, Elisa M EM; Sprick, Martin R MR; Trumpp, Andreas A; Jacks, Tyler T
Publication Date: 2017-10-23

Variant appearance in text: KRAS: A11T
PubMed Link: 29061961
Variant Present in the following documents:
  • 41467_2017_942_MOESM1_ESM.pdf
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: 31G>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis.

Plos Medicine
Sivakumar, Shivan S; de Santiago, Ines I; Chlon, Leon L; Markowetz, Florian F
Publication Date: 2017-01

Variant appearance in text: KRAS: A11T
PubMed Link: 28141826
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms.

Oncotarget
Lee, Yi-Ju YJ; Lee, Ming-Yung MY; Ruan, Alexandra A; Chen, Chi-Kuan CK; Liu, Hao-Ping HP; Wang, Chau-Jong CJ; Chao, Wan-Ru WR; Han, Chih-Ping CP
Publication Date: 2016-12-13

Variant appearance in text: KRAS: A11T
PubMed Link: 27888800
Variant Present in the following documents:
  • Main text
  • oncotarget-07-82097.pdf
View BVdb publication page



Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016

Variant appearance in text: KRAS: 31G>A
PubMed Link: 26785607
Variant Present in the following documents:
  • kcbt-17-03-1139235.pdf
View BVdb publication page



Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016-01-18

Variant appearance in text: KRAS: 31G>A
PubMed Link: 26782967
Variant Present in the following documents:
  • 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One
Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M
Publication Date: 2015

Variant appearance in text: KRAS: A11T
PubMed Link: 26010451
Variant Present in the following documents:
  • pone.0127146.s014.xlsx, sheet 3
View BVdb publication page