LRRK2 c.2863T>G ;(p.S955A)

Variant ID: 12-40688701-T-G

NM_198578.3(LRRK2):c.2863T>G;(p.S955A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.

Cells
Marchand, Antoine A; Sarchione, Alessia A; Athanasopoulos, Panagiotis S PS; Roy, Hélène Bauderlique-Le HB; Goveas, Liesel L; Magnez, Romain R; Drouyer, Matthieu M; Emanuele, Marco M; Ho, Franz Y FY; Liberelle, Maxime M; Melnyk, Patricia P; Lebègue, Nicolas N; Thuru, Xavier X; Nichols, R Jeremy RJ; Greggio, Elisa E; Kortholt, Arjan A; Galli, Thierry T; Chartier-Harlin, Marie-Christine MC; Taymans, Jean-Marc JM
Publication Date: 2022-03-17

Variant appearance in text: LRRK2: S955A
PubMed Link: 35326469
Variant Present in the following documents:
  • Main text
  • cells-11-01018.pdf
View BVdb publication page



LRRK2 Phosphorylation, More Than an Epiphenomenon.

Frontiers In Neuroscience
Marchand, Antoine A; Drouyer, Matthieu M; Sarchione, Alessia A; Chartier-Harlin, Marie-Christine MC; Taymans, Jean-Marc JM
Publication Date: 2020

Variant appearance in text: LRRK2: S955A
PubMed Link: 32612495
Variant Present in the following documents:
  • Main text
  • fnins-14-00527.pdf
View BVdb publication page



Inhibition of LRRK2 or Casein Kinase 1 Results in LRRK2 Protein Destabilization.

Molecular Neurobiology
De Wit, T T; Baekelandt, V V; Lobbestael, E E
Publication Date: 2019-08

Variant appearance in text: LRRK2: S955A
PubMed Link: 30592011
Variant Present in the following documents:
  • 12035_2018_Article_1449.pdf
View BVdb publication page



LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site status.

Frontiers In Molecular Neuroscience
Reynolds, April A; Doggett, Elizabeth A EA; Riddle, Steve M SM; Lebakken, Connie S CS; Nichols, R Jeremy RJ
Publication Date: 2014

Variant appearance in text: LRRK2: Ser955Ala
PubMed Link: 25009464
Variant Present in the following documents:
  • Main text
  • fnmol-07-00054.pdf
View BVdb publication page