Changes in Liver Lipidomic Profile in G2019S-LRRK2 Mouse Model of Parkinson's Disease.
Cells
Corral Nieto, Yaiza Y; Yakhine-Diop, Sokhna M S SMS; Moreno-Cruz, Paula P; Manrique García, Laura L; Gabrielly Pereira, Amanda A; Morales-García, José A JA; Niso-Santano, Mireia M; González-Polo, Rosa A RA; Uribe-Carretero, Elisabet E; Durand, Sylvère S; Maiuri, Maria Chiara MC; Paredes-Barquero, Marta M; Alegre-Cortés, Eva E; Canales-Cortés, Saray S; López de Munain, Adolfo A; Pérez-Tur, Jordi J; Pérez-Castillo, Ana A; Kroemer, Guido G; Fuentes, José M JM; Bravo-San Pedro, José M JM
Development of mutation-selective LRRK2 kinase inhibitors as precision medicine for Parkinson's disease and other diseases for which carriers are at increased risk.
Frontiers In Neurology
Lesniak, Robert K RK; Nichols, R Jeremy RJ; Montine, Thomas J TJ
Effect Modification between Genes and Environment and Parkinson's Disease Risk.
Annals Of Neurology
Periñán, Maria Teresa MT; Brolin, Kajsa K; Bandres-Ciga, Sara S; Blauwendraat, Cornelis C; Klein, Christine C; Gan-Or, Ziv Z; Singleton, Andrew A; Gomez-Garre, Pilar P; Swanberg, Maria M; Mir, Pablo P; Noyce, Alastair A
A Review on Response to Device-Aided Therapies Used in Monogenic Parkinsonism and GBA Variants Carriers: A Need for Guidelines and Comparative Studies.
Journal Of Parkinson'S Disease
Salles, Philippe A PA; Liao, James J; Shuaib, Umar U; Mata, Ignacio F IF; Fernandez, Hubert H HH
LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains.
Plos Biology
Weng, Jui-Hung JH; Aoto, Phillip C PC; Lorenz, Robin R; Wu, Jian J; Schmidt, Sven H SH; Manschwetus, Jascha T JT; Kaila-Sharma, Pallavi P; Silletti, Steve S; Mathea, Sebastian S; Chatterjee, Deep D; Knapp, Stefan S; Herberg, Friedrich W FW; Taylor, Susan S SS
A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity.
Frontiers In Cell And Developmental Biology
Rosenbusch, Katharina E KE; Oun, Asmaa A; Sanislav, Oana O; Lay, Sui T ST; Keizer-Gunnink, Ineke I; Annesley, Sarah J SJ; Fisher, Paul R PR; Dolga, Amalia M AM; Kortholt, Arjan A
R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils.
Acta Neuropathologica
Fan, Ying Y; Nirujogi, Raja S RS; Garrido, Alicia A; Ruiz-Martínez, Javier J; Bergareche-Yarza, Alberto A; Mondragón-Rezola, Elisabet E; Vinagre-Aragón, Ana A; Croitoru, Ioana I; Gorostidi Pagola, Ana A; Paternain Markinez, Laura L; Alcalay, Roy R; Hickman, Richard A RA; Düring, Jonas J; Gomes, Sara S; Pratuseviciute, Neringa N; Padmanabhan, Shalini S; Valldeoriola, Francesc F; Pérez Sisqués, Leticia L; Malagelada, Cristina C; Ximelis, Teresa T; Molina Porcel, Laura L; Martí, Maria José MJ; Tolosa, Eduardo E; Alessi, Dario R DR; Sammler, Esther M EM
A More Homogeneous Phenotype in Parkinson's Disease Related to R1441G Mutation in the LRRK2 Gene.
Frontiers In Neurology
Vinagre-Aragón, Ana A; Campo-Caballero, David D; Mondragón-Rezola, Elisabet E; Pardina-Vilella, Lara L; Hernandez Eguiazu, Haizea H; Gorostidi, Ana A; Croitoru, Ioana I; Bergareche, Alberto A; Ruiz-Martinez, Javier J