Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.
The Journal Of Biological Chemistry
Wu, Chun-Xiang CX; Liao, Jingling J; Park, Yangshin Y; Reed, Xylena X; Engel, Victoria A VA; Hoang, Neo C NC; Takagi, Yuichiro Y; Johnson, Steven M SM; Wang, Mu M; Federici, Mark M; Nichols, R Jeremy RJ; Sanishvili, Ruslan R; Cookson, Mark R MR; Hoang, Quyen Q QQ