LRRK2 c.6091A>G ;(p.T2031A)

Variant ID: 12-40734238-A-G

NM_198578.3(LRRK2):c.6091A>G;(p.T2031A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Models for LRRK2-Linked Parkinsonism.

Parkinson'S Disease
Li, Tianxia T; Yang, Dejun D; Sushchky, Sarah S; Liu, Zhaohui Z; Smith, Wanli W WW
Publication Date: 2011

Variant appearance in text: LRRK2: T2031A
PubMed Link: 21603132
Variant Present in the following documents:
  • Main text
  • PD2011-942412.pdf
View BVdb publication page



Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2.

The Journal Of Biological Chemistry
Li, Xiaojie X; Moore, Darren J DJ; Xiong, Yulan Y; Dawson, Ted M TM; Dawson, Valina L VL
Publication Date: 2010-09-17

Variant appearance in text: LRRK2: T2031A
PubMed Link: 20595391
Variant Present in the following documents:
  • Main text
View BVdb publication page



GTPase activity plays a key role in the pathobiology of LRRK2.

Plos Genetics
Xiong, Yulan Y; Coombes, Candice E CE; Kilaru, Austin A; Li, Xiaojie X; Gitler, Aaron D AD; Bowers, William J WJ; Dawson, Valina L VL; Dawson, Ted M TM; Moore, Darren J DJ
Publication Date: 2010-04-08

Variant appearance in text: LRRK2: T2031A
PubMed Link: 20386743
Variant Present in the following documents:
  • Main text
View BVdb publication page