Publications:

---

LRRK2 Phosphorylation, More Than an Epiphenomenon.

Frontiers In Neuroscience

Marchand, Antoine A; Drouyer, Matthieu M; Sarchione, Alessia A; Chartier-Harlin, Marie-Christine MC; Taymans, Jean-Marc JM

Publication Date: 2020

Variant appearance in text: LRRK2: T2035A

PubMed Link: 32612495

Variant Present in the following documents:

• Main text
• fnins-14-00527.pdf

View BVdb publication page

---

GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.

Human Molecular Genetics

Blanca Ramírez, Marian M; Lara Ordóñez, Antonio Jesús AJ; Fdez, Elena E; Madero-Pérez, Jesús J; Gonnelli, Adriano A; Drouyer, Matthieu M; Chartier-Harlin, Marie-Christine MC; Taymans, Jean-Marc JM; Bubacco, Luigi L; Greggio, Elisa E; Hilfiker, Sabine S

Publication Date: 2017-07-15

Variant appearance in text: LRRK2: T2035A

PubMed Link: 28453723

Variant Present in the following documents:

• Main text
• ddx161.pdf

View BVdb publication page

---

Lack of correlation between the kinase activity of LRRK2 harboring kinase-modifying mutations and its phosphorylation at Ser910, 935, and Ser955.

Plos One

Ito, Genta G; Fujimoto, Tetta T; Kamikawaji, Shogo S; Kuwahara, Tomoki T; Iwatsubo, Takeshi T

Publication Date: 2014

Variant appearance in text: LRRK2: T2035A

PubMed Link: 24836358

Variant Present in the following documents:

• Main text
• pone.0097988.pdf

View BVdb publication page

---

Models for LRRK2-Linked Parkinsonism.

Parkinson'S Disease

Li, Tianxia T; Yang, Dejun D; Sushchky, Sarah S; Liu, Zhaohui Z; Smith, Wanli W WW

Publication Date: 2011

Variant appearance in text: LRRK2: T2035A

PubMed Link: 21603132

Variant Present in the following documents:

• Main text
• PD2011-942412.pdf

View BVdb publication page

---

Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2.

The Journal Of Biological Chemistry

Li, Xiaojie X; Moore, Darren J DJ; Xiong, Yulan Y; Dawson, Ted M TM; Dawson, Valina L VL

Publication Date: 2010-09-17

Variant appearance in text: LRRK2: T2035A

PubMed Link: 20595391

Variant Present in the following documents:

• Main text

View BVdb publication page

---

GTPase activity plays a key role in the pathobiology of LRRK2.

Plos Genetics

Xiong, Yulan Y; Coombes, Candice E CE; Kilaru, Austin A; Li, Xiaojie X; Gitler, Aaron D AD; Bowers, William J WJ; Dawson, Valina L VL; Dawson, Ted M TM; Moore, Darren J DJ

Publication Date: 2010-04-08

Variant appearance in text: LRRK2: T2035A

PubMed Link: 20386743

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation.

The Journal Of Biological Chemistry

Greggio, Elisa E; Zambrano, Ibardo I; Kaganovich, Alice A; Beilina, Alexandra A; Taymans, Jean-Marc JM; Daniëls, Veronique V; Lewis, Patrick P; Jain, Shushant S; Ding, Jinhui J; Syed, Ali A; Thomas, Kelly J KJ; Baekelandt, Veerle V; Cookson, Mark R MR

Publication Date: 2008-06-13

Variant appearance in text: LRRK2: T2035A

PubMed Link: 18397888

Variant Present in the following documents:

• Main text

View BVdb publication page

---