Publications:

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The N-terminal autoinhibitory module of the A1 domain in von Willebrand factor stabilizes the mechanosensor catch bond.

Rsc Chemical Biology

Zhao, Yunduo Charles YC; Wang, Haoqing H; Wang, Yao Y; Lou, Jizhong J; Ju, Lining Arnold LA

Publication Date: 2022-06-08

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PubMed Link: 35755187

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• CB-003-D2CB00010E.pdf

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Shear Stress Accumulation Enhances von Willebrand Factor-Induced Platelet P-Selectin Translocation in a PI3K/Akt Pathway-Dependent Manner.

Frontiers In Cell And Developmental Biology

Fang, Jinhua J; Sun, Xiaoxi X; Liu, Silu S; Yang, Pu P; Lin, Jiangguo J; Feng, Jingjing J; Cruz, Miguel A MA; Dong, Jing-Fei JF; Fang, Ying Y; Wu, Jianhua J

Publication Date: 2021

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PubMed Link: 34141704

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• Main text
• fcell-09-642108.pdf

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Sialylation on O-linked glycans protects von Willebrand factor from macrophage galactose lectin-mediated clearance.

Haematologica

Ward, Soracha E SE; O'Sullivan, Jamie M JM; Moran, Alan B AB; Spencer, Daniel I R DIR; Gardner, Richard A RA; Sharma, Jyotika J; Fazavana, Judicael J; Monopoli, Marco M; McKinnon, Thomas A J TAJ; Chion, Alain A; Haberichter, Sandra S; O'Donnell, James S JS

Publication Date: 2022-03-01

Variant appearance in text: VWF: R1450E

PubMed Link: 33763999

Variant Present in the following documents:

• Main text
• 107668.pdf

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Cooperative unfolding of distinctive mechanoreceptor domains transduces force into signals.

Elife

Ju, Lining L; Chen, Yunfeng Y; Xue, Lingzhou L; Du, Xiaoping X; Zhu, Cheng C

Publication Date: 2016-07-19

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PubMed Link: 27434669

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• Main text
• elife-15447.pdf

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Free hemoglobin increases von Willebrand factor-mediated platelet adhesion in vitro: implications for circulatory devices.

Blood

Da, Qi Q; Teruya, Miho M; Guchhait, Prasenjit P; Teruya, Jun J; Olson, John S JS; Cruz, Miguel A MA

Publication Date: 2015-11-12

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PubMed Link: 26307534

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• Main text

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Structural origins of misfolding propensity in the platelet adhesive von Willebrand factor A1 domain.

Biophysical Journal

Zimmermann, Michael T MT; Tischer, Alexander A; Whitten, Steven T ST; Auton, Matthew M

Publication Date: 2015-07-21

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PubMed Link: 26200876

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Exploiting the kinetic interplay between GPIbα-VWF binding interfaces to regulate hemostasis and thrombosis.

Blood

Chen, Jianchung J; Zhou, Hairu H; Diacovo, Alexander A; Zheng, X Long XL; Emsley, Jonas J; Diacovo, Thomas G TG

Publication Date: 2014-12-11

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PubMed Link: 25293780

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Platelet adhesion involves a novel interaction between vimentin and von Willebrand factor under high shear stress.

Blood

Da, Qi Q; Behymer, Molly M; Correa, Juliana I JI; Vijayan, K Vinod KV; Cruz, Miguel A MA

Publication Date: 2014-04-24

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PubMed Link: 24642750

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The N-terminal flanking region of the A1 domain regulates the force-dependent binding of von Willebrand factor to platelet glycoprotein Ibα.

The Journal Of Biological Chemistry

Ju, Lining L; Dong, Jing-Fei JF; Cruz, Miguel A MA; Zhu, Cheng C

Publication Date: 2013-11-08

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PubMed Link: 24062306

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An HMM-based algorithm for evaluating rates of receptor-ligand binding kinetics from thermal fluctuation data.

Bioinformatics (Oxford, England)

Ju, Lining L; Wang, Yijie Dylan YD; Hung, Ying Y; Wu, Chien-Fu Jeff CF; Zhu, Cheng C

Publication Date: 2013-06-15

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PubMed Link: 23599504

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The catch bond mechanism between von Willebrand factor and platelet surface receptors investigated by molecular dynamics simulations.

Proteins

Interlandi, Gianluca G; Thomas, Wendy W

Publication Date: 2010-08-15

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PubMed Link: 20602356

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Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibalpha and platelet activation under shear stress.

The Journal Of Biological Chemistry

Auton, Matthew M; Sowa, Katie E KE; Smith, Scott M SM; Sedlák, Erik E; Vijayan, K Vinod KV; Cruz, Miguel A MA

Publication Date: 2010-07-23

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PubMed Link: 20498367

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