A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD.
Blood Advances
Shi, Qizhen Q; Fahs, Scot A SA; Mattson, Jeremy G JG; Yu, Hongyin H; Perry, Crystal L CL; Morateck, Patricia A PA; Schroeder, Jocelyn A JA; Rapten, Jessica J; Weiler, Hartmut H; Montgomery, Robert R RR
Solution structure of the major factor VIII binding region on von Willebrand factor.
Blood
Shiltagh, Nuha N; Kirkpatrick, John J; Cabrita, Lisa D LD; McKinnon, Tom A J TA; Thalassinos, Konstantinos K; Tuddenham, Edward G D EG; Hansen, D Flemming DF