CD4 c.166_167delinsAA ;(p.S56N)

Variant ID: 12-6909589-TC-AA

NM_000616.4(CD4):c.166_167delinsAA;(p.S56N)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4+ T Cells by NK Cells.

Journal Of Virology
Sugden, Scott M SM; Pham, Tram N Q TNQ; Cohen, Éric A ÉA
Publication Date: 2017-04-15

Variant appearance in text: CD4: S56N
PubMed Link: 28148794
Variant Present in the following documents:
  • Main text
View BVdb publication page



Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Cell
Escolano, Amelia A; Steichen, Jon M JM; Dosenovic, Pia P; Kulp, Daniel W DW; Golijanin, Jovana J; Sok, Devin D; Freund, Natalia T NT; Gitlin, Alexander D AD; Oliveira, Thiago T; Araki, Tatsuya T; Lowe, Sarina S; Chen, Spencer T ST; Heinemann, Jennifer J; Yao, Kai-Hui KH; Georgeson, Erik E; Saye-Francisco, Karen L KL; Gazumyan, Anna A; Adachi, Yumiko Y; Kubitz, Michael M; Burton, Dennis R DR; Schief, William R WR; Nussenzweig, Michel C MC
Publication Date: 2016-09-08

Variant appearance in text: CD4: S56N
PubMed Link: 27610569
Variant Present in the following documents:
  • Main text
View BVdb publication page



Vpu Protein: The Viroporin Encoded by HIV-1.

Viruses
González, María Eugenia ME
Publication Date: 2015-08-04

Variant appearance in text: CD4: S56N
PubMed Link: 26247957
Variant Present in the following documents:
  • Main text
  • viruses-07-02824.pdf
View BVdb publication page



A comparative mutational analysis of HIV-1 Vpu subtypes B and C for the identification of determinants required to counteract BST-2/Tetherin and enhance viral egress.

Virology
Douglas, Janet L JL; Bai, Ying Y; Gustin, Jean K JK; Moses, Ashlee V AV
Publication Date: 2013-07-05

Variant appearance in text: CD4: S56N
PubMed Link: 23582304
Variant Present in the following documents:
  • Main text
View BVdb publication page



BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action.

Virology
Skasko, Mark M; Tokarev, Andrey A; Chen, Cheng-Chang CC; Fischer, Wolfgang B WB; Pillai, Satish K SK; Guatelli, John J
Publication Date: 2011-03-01

Variant appearance in text: CD4: S56N
PubMed Link: 21237475
Variant Present in the following documents:
  • Main text
View BVdb publication page



Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism.

Journal Of Virology
Douglas, Janet L JL; Viswanathan, Kasinath K; McCarroll, Matthew N MN; Gustin, Jean K JK; Früh, Klaus K; Moses, Ashlee V AV
Publication Date: 2009-08

Variant appearance in text: CD4: S56N
PubMed Link: 19515779
Variant Present in the following documents:
  • Main text
View BVdb publication page