CD4 c.212A>G ;(p.K71R)

Variant ID: 12-6909635-A-G

NM_000616.4(CD4):c.212A>G;(p.K71R)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat.

Mbio
Liang, Taizhen T; Zhang, Qiao Q; Wu, Ziyao Z; Chen, Pei P; Huang, Yifan Y; Liu, Shuwen S; Li, Lin L
Publication Date: 2021-08-31

Variant appearance in text: CD4: K71R
PubMed Link: 34465029
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Novel HIV-1 Nef Mutation in a Primary Pediatric Isolate Impairs MHC-Class I Downregulation and Cytopathicity.

Aids Research And Human Retroviruses
Ali, Ayub A; Furler, Robert L RL; Pedroza-Martins, Livia L; Colantonio, Arnaud D AD; Anisman-Posner, Deborah D; Bryson, Yvonne Y; Yang, Otto O OO; Uittenbogaart, Christel H CH
Publication Date: 2020-02

Variant appearance in text: CD4: K71R
PubMed Link: 31571497
Variant Present in the following documents:
  • Main text
View BVdb publication page



The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.

The Journal Of Biological Chemistry
Ting, Yi Tian YT; Petersen, Jan J; Ramarathinam, Sri H SH; Scally, Stephen W SW; Loh, Khai L KL; Thomas, Ranjeny R; Suri, Anish A; Baker, Daniel G DG; Purcell, Anthony W AW; Reid, Hugh H HH; Rossjohn, Jamie J
Publication Date: 2018-03-02

Variant appearance in text: CD4: K71R
PubMed Link: 29317506
Variant Present in the following documents:
  • Main text
View BVdb publication page



Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat.

Retrovirology
Chen, Shiyou S; Yang, Xiaodan X; Cheng, Weijia W; Ma, Yuhong Y; Shang, Yafang Y; Cao, Liu L; Chen, Shuliang S; Chen, Yu Y; Wang, Min M; Guo, Deyin D
Publication Date: 2017-02-13

Variant appearance in text: CD4: K71R
PubMed Link: 28193275
Variant Present in the following documents:
  • Main text
  • 12977_2017_Article_338.pdf
View BVdb publication page



Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes.

Journal Of Virology
Sagnier, Sophie S; Daussy, Coralie F CF; Borel, Sophie S; Robert-Hebmann, Véronique V; Faure, Mathias M; Blanchet, Fabien P FP; Beaumelle, Bruno B; Biard-Piechaczyk, Martine M; Espert, Lucile L
Publication Date: 2015-01

Variant appearance in text: CD4: K71R
PubMed Link: 25339774
Variant Present in the following documents:
  • Main text
View BVdb publication page



HIV-2 integrase polymorphisms and longitudinal genotypic analysis of HIV-2 infected patients failing a raltegravir-containing regimen.

Plos One
Cavaco-Silva, Joana J; Abecasis, Ana A; Miranda, Ana Cláudia AC; Poças, José J; Narciso, Jorge J; Águas, Maria João MJ; Maltez, Fernando F; Almeida, Isabel I; Germano, Isabel I; Diniz, António A; Gonçalves, Maria de Fátima Mde F; Gomes, Perpétua P; Cunha, Celso C; Camacho, Ricardo Jorge RJ; ,
Publication Date: 2014

Variant appearance in text: CD4: K71R
PubMed Link: 24681625
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site.

Mabs
Xia, Tian T; Liang, Shuaiyi S; Wang, Huajing H; Hu, Shi S; Sun, Yuna Y; Yu, Xiaojie X; Han, Jun J; Li, Jun J; Guo, Shangjing S; Dai, Jianxin J; Lou, Zhiyong Z; Guo, Yajun Y
Publication Date: 2014

Variant appearance in text: CD4: K71R
PubMed Link: 24423621
Variant Present in the following documents:
  • Main text
View BVdb publication page