CD4 c.248G>A ;(p.R83K)

Variant ID: 12-6923341-G-A

NM_000616.4(CD4):c.248G>A;(p.R83K)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.

Journal Of Internal Medicine
Jädersten, Martin M; Lilienthal, Ingrid I; Tsesmetzis, Nikolaos N; Lourda, Magda M; Bengtzén, Sofia S; Bohlin, Anna A; Arnroth, Cornelia C; Erkers, Tom T; Seashore-Ludlow, Brinton B; Giraud, Géraldine G; Barkhordar, Giti S GS; Tao, Sijia S; Fogelstrand, Linda L; Saft, Leonie L; Östling, Päivi P; Schinazi, Raymond F RF; Kim, Baek B; Schaller, Torsten T; Juliusson, Gunnar G; Deneberg, Stefan S; Lehmann, Sören S; Rassidakis, Georgios Z GZ; Höglund, Martin M; Henter, Jan-Inge JI; Herold, Nikolas N
Publication Date: 2022-12

Variant appearance in text: CD4: 248G>A; Arg83His
PubMed Link: 35934913
Variant Present in the following documents:
  • JOIM-292-925-s001.pdf
View BVdb publication page



Emergence of the G118R Pan-Integrase Resistance Mutation as a Result of Low Compliance to a Dolutegravir-Based cART.

Infectious Disease Reports
Mens, Helene H; Fjordside, Lasse L; Fonager, Jannik J; Gerstoft, Jan J
Publication Date: 2022-06-22

Variant appearance in text: CD4: R83K
PubMed Link: 35893472
Variant Present in the following documents:
  • idr-14-00053.pdf
View BVdb publication page



Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis.

Nature Communications
Savola, P P; Kelkka, T T; Rajala, H L HL; Kuuliala, A A; Kuuliala, K K; Eldfors, S S; Ellonen, P P; Lagström, S S; Lepistö, M M; Hannunen, T T; Andersson, E I EI; Khajuria, R K RK; Jaatinen, T T; Koivuniemi, R R; Repo, H H; Saarela, J J; Porkka, K K; Leirisalo-Repo, M M; Mustjoki, S S
Publication Date: 2017-06-21

Variant appearance in text: CD4: R83K
PubMed Link: 28635960
Variant Present in the following documents:
  • ncomms15869-s1.pdf
View BVdb publication page



Two cases of possible transmitted drug-resistant HIV: likely HIV superinfection and unmasking of pre-existing resistance.

International Journal Of Std & Aids
Martin, Fabiola F; Lee, John J; Thomson, Emma E; Tarrant, Nick N; Hale, Antony A; Lacey, Charles J CJ
Publication Date: 2016-01

Variant appearance in text: CD4: R83K
PubMed Link: 25663247
Variant Present in the following documents:
  • Main text
  • 10.1177_0956462415571671.pdf
View BVdb publication page



Zidovudine (AZT) monotherapy selects for the A360V mutation in the connection domain of HIV-1 reverse transcriptase.

Plos One
Brehm, Jessica H JH; Scott, Yanille Y; Koontz, Dianna L DL; Perry, Steven S; Hammer, Scott S; Katzenstein, David D; Mellors, John W JW; Sluis-Cremer, Nicolas N; ,
Publication Date: 2012

Variant appearance in text: CD4: R83K
PubMed Link: 22363673
Variant Present in the following documents:
  • Main text
  • pone.0031558.pdf
View BVdb publication page



Precise identification of a human immunodeficiency virus type 1 antigen processing mutant.

Journal Of Virology
Zimbwa, Peter P; Milicic, Anita A; Frater, John J; Scriba, Thomas J TJ; Willis, Antony A; Goulder, Philip J R PJ; Pillay, Tilly T; Gunthard, Huldrych H; Weber, Jonathan N JN; Zhang, Hua-Tang HT; Phillips, Rodney E RE
Publication Date: 2007-02

Variant appearance in text: CD4: R83K
PubMed Link: 17108020
Variant Present in the following documents:
  • Main text
View BVdb publication page



Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors.

Journal Of Virology
Svicher, Valentina V; Sing, Tobias T; Santoro, Maria Mercedes MM; Forbici, Federica F; Rodríguez-Barrios, Fátima F; Bertoli, Ada A; Beerenwinkel, Niko N; Bellocchi, Maria Concetta MC; Gago, Federigo F; d'Arminio Monforte, Antonella A; Antinori, Andrea A; Lengauer, Thomas T; Ceccherini-Silberstein, Francesca F; Perno, Carlo Federico CF
Publication Date: 2006-07

Variant appearance in text: CD4: R83K
PubMed Link: 16809324
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture.

Journal Of Clinical Microbiology
Dykes, Carrie C; Wang, Jiong J; Jin, Xia X; Planelles, Vicente V; An, Dong Sung DS; Tallo, Amanda A; Huang, Yangxin Y; Wu, Hulin H; Demeter, Lisa M LM
Publication Date: 2006-06

Variant appearance in text: CD4: R83K
PubMed Link: 16757582
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gln145Met/Leu changes in human immunodeficiency virus type 1 reverse transcriptase confer resistance to nucleoside and nonnucleoside analogs and impair virus replication.

Antimicrobial Agents And Chemotherapy
Paolucci, Stefania S; Baldanti, Fausto F; Maga, Giovanni G; Cancio, Reynel R; Zazzi, Maurizio M; Zavattoni, Maurizio M; Chiesa, Antonella A; Spadari, Silvio S; Gerna, Giuseppe G
Publication Date: 2004-12

Variant appearance in text: CD4: Arg83Lys
PubMed Link: 15561833
Variant Present in the following documents:
  • Main text
View BVdb publication page