Neutralization Sensitivity and Evolution of Virus in a Chronic HIV-1 Clade B Infected Patient with Neutralizing Activity against Membrane-Proximal External Region.
An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nature Communications
Zhang, Lei L; Irimia, Adriana A; He, Lingling L; Landais, Elise E; Rantalainen, Kimmo K; Leaman, Daniel P DP; Vollbrecht, Thomas T; Stano, Armando A; Sands, Daniel I DI; Kim, Arthur S AS; , ; Poignard, Pascal P; Burton, Dennis R DR; Murrell, Ben B; Ward, Andrew B AB; Zhu, Jiang J; Wilson, Ian A IA; Zwick, Michael B MB
HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization.
Plos Pathogens
Navis, Marjon M; Tran, Karen K; Bale, Shridhar S; Phad, Ganesh E GE; Guenaga, Javier J; Wilson, Richard R; Soldemo, Martina M; McKee, Krisha K; Sundling, Christopher C; Mascola, John J; Li, Yuxing Y; Wyatt, Richard T RT; Karlsson Hedestam, Gunilla B GB
Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Tran, Karen K; Poulsen, Christian C; Guenaga, Javier J; de Val, Natalia N; de Val Alda, Natalia N; Wilson, Richard R; Sundling, Christopher C; Li, Yuxing Y; Stanfield, Robyn L RL; Wilson, Ian A IA; Ward, Andrew B AB; Karlsson Hedestam, Gunilla B GB; Wyatt, Richard T RT