CD4 c.298A>G ;(p.K100E)

Variant ID: 12-6923391-A-G

NM_000616.4(CD4):c.298A>G;(p.K100E)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Neutralization Sensitivity and Evolution of Virus in a Chronic HIV-1 Clade B Infected Patient with Neutralizing Activity against Membrane-Proximal External Region.

Pathogens (Basel, Switzerland)
Tang, Wenqi W; Yuan, Zhenzhen Z; Wang, Zheng Z; Ren, Li L; Li, Dan D; Wang, Shuhui S; Hao, Yanling Y; Li, Jing J; Shen, Xiuli X; Ruan, Yuhua Y; Shao, Yiming Y; Liu, Ying Y
Publication Date: 2023-03-22

Variant appearance in text: CD4: K100E
PubMed Link: 36986419
Variant Present in the following documents:
  • Main text
  • pathogens-12-00497.pdf
View BVdb publication page



An MPER antibody neutralizes HIV-1 using germline features shared among donors.

Nature Communications
Zhang, Lei L; Irimia, Adriana A; He, Lingling L; Landais, Elise E; Rantalainen, Kimmo K; Leaman, Daniel P DP; Vollbrecht, Thomas T; Stano, Armando A; Sands, Daniel I DI; Kim, Arthur S AS; , ; Poignard, Pascal P; Burton, Dennis R DR; Murrell, Ben B; Ward, Andrew B AB; Zhu, Jiang J; Wilson, Ian A IA; Zwick, Michael B MB
Publication Date: 2019-11-26

Variant appearance in text: CD4: K100e
PubMed Link: 31772165
Variant Present in the following documents:
  • 41467_2019_Article_12973.pdf
View BVdb publication page



HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization.

Plos Pathogens
Navis, Marjon M; Tran, Karen K; Bale, Shridhar S; Phad, Ganesh E GE; Guenaga, Javier J; Wilson, Richard R; Soldemo, Martina M; McKee, Krisha K; Sundling, Christopher C; Mascola, John J; Li, Yuxing Y; Wyatt, Richard T RT; Karlsson Hedestam, Gunilla B GB
Publication Date: 2014-08

Variant appearance in text: CD4: K100e
PubMed Link: 25166308
Variant Present in the following documents:
  • Main text
View BVdb publication page



Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Tran, Karen K; Poulsen, Christian C; Guenaga, Javier J; de Val, Natalia N; de Val Alda, Natalia N; Wilson, Richard R; Sundling, Christopher C; Li, Yuxing Y; Stanfield, Robyn L RL; Wilson, Ian A IA; Ward, Andrew B AB; Karlsson Hedestam, Gunilla B GB; Wyatt, Richard T RT
Publication Date: 2014-02-18

Variant appearance in text: CD4: K100e
PubMed Link: 24550318
Variant Present in the following documents:
  • Main text
View BVdb publication page