CD4 c.412_413delinsGC ;(p.S138A)

Variant ID: 12-6923963-AG-GC

NM_000616.4(CD4):c.412_413delinsGC;(p.S138A)

This variant was identified in 20 publications

View GRCh38 version.




Publications:


Bcl10 is associated with actin dynamics at the T cell immune synapse.

Cellular Immunology
Wagh, Kaustubh K; Wheatley, Brittany A BA; Traver, Maria K MK; Hussain, Imran I; Schaefer, Brian C BC; Upadhyaya, Arpita A
Publication Date: 2020-10

Variant appearance in text: CD4: Ser138Ala
PubMed Link: 32768663
Variant Present in the following documents:
  • Main text
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Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors.

Viruses
Yu, Danwei D; Su, Yang Y; Ding, Xiaohui X; Zhu, Yuanmei Y; Qin, Bo B; Chong, Huihui H; Cui, Sheng S; He, Yuxian Y
Publication Date: 2020-03-18

Variant appearance in text: CD4: S138A
PubMed Link: 32197300
Variant Present in the following documents:
  • Main text
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Prevalence of Transmitted Drug-Resistance Mutations and Polymorphisms in HIV-1 Reverse Transcriptase, Protease, and gp41 Sequences Among Recent Seroconverters in Southern Poland.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Smoleń-Dzirba, Joanna J; Rosińska, Magdalena M; Kruszyński, Piotr P; Bratosiewicz-Wąsik, Jolanta J; Wojtyczka, Robert R; Janiec, Janusz J; Szetela, Bartosz B; Beniowski, Marek M; Bociąga-Jasik, Monika M; Jabłonowska, Elżbieta E; Wąsik, Tomasz J TJ; The Cascade Collaboration In EuroCoord, And A
Publication Date: 2017-02-07

Variant appearance in text: CD4: S138A
PubMed Link: 28167814
Variant Present in the following documents:
  • Main text
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Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method.

Antiviral Chemistry & Chemotherapy
Miyamoto, Fusako F; Kawaji, Kumi K; Oishi, Shinya S; Fujii, Nobutaka N; Kaku, Mitsuo M; Kodama, Eiichi N EN
Publication Date: 2015-04

Variant appearance in text: CD4: S138A
PubMed Link: 26527820
Variant Present in the following documents:
  • Main text
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Mechanism of HIV-1 Resistance to Short-Peptide Fusion Inhibitors Targeting the Gp41 Pocket.

Journal Of Virology
Su, Yang Y; Chong, Huihiui H; Qiu, Zonglin Z; Xiong, Shengwen S; He, Yuxian Y
Publication Date: 2015-06

Variant appearance in text: CD4: S138A
PubMed Link: 25787278
Variant Present in the following documents:
  • Main text
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H7N9: a low pathogenic avian influenza A virus infecting humans.

Current Opinion In Virology
Liu, Jun J; Xiao, Haixia H; Wu, Yan Y; Liu, Di D; Qi, Xiaopeng X; Shi, Yi Y; Gao, George F GF
Publication Date: 2014-04

Variant appearance in text: CD4: S138A
PubMed Link: 24705093
Variant Present in the following documents:
  • Main text
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Characterization of Gp41 polymorphisms in the fusion peptide domain and T-20 (Enfuvirtide) resistance-associated regions in Korean HIV-1 isolates.

Journal Of Korean Medical Science
Jang, Dai-Ho DH; Yoon, Cheol-Hee CH; Choi, Byeong-Sun BS; Chung, Yoon-Seok YS; Kim, Hye-Young HY; Chi, Sung-Gil SG; Kim, Sung Soon SS
Publication Date: 2014-03

Variant appearance in text: CD4: S138A
PubMed Link: 24616600
Variant Present in the following documents:
  • Main text
  • jkms-29-456.pdf
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Genetic analysis and natural polymorphisms in HIV-1 gp41 isolates from Maputo City, Mozambique.

Aids Research And Human Retroviruses
Ismael, Nália N; Bila, Dulce D; Mariani, Diana D; Vubil, Adolfo A; Mabunda, Nedio N; Abreu, Celina C; Jani, Ilesh I; Tanuri, Amilcar A
Publication Date: 2014-06

Variant appearance in text: CD4: S138A
PubMed Link: 24188582
Variant Present in the following documents:
  • Main text
View BVdb publication page



Computer-Aided Approaches for Targeting HIVgp41.

Biology
Allen, William J WJ; Rizzo, Robert C RC
Publication Date: 2012-08-20

Variant appearance in text: CD4: S138A
PubMed Link: 23730525
Variant Present in the following documents:
  • Main text
  • biology-01-00311.pdf
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Resistance of human immunodeficiency virus type 1 to a third-generation fusion inhibitor requires multiple mutations in gp41 and is accompanied by a dramatic loss of gp41 function.

Journal Of Virology
Eggink, Dirk D; Bontjer, Ilja I; Langedijk, Johannes P M JP; Berkhout, Ben B; Sanders, Rogier W RW
Publication Date: 2011-10

Variant appearance in text: CD4: S138A
PubMed Link: 21835789
Variant Present in the following documents:
  • Main text
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Impact of the HIV-1 env genetic context outside HR1-HR2 on resistance to the fusion inhibitor enfuvirtide and viral infectivity in clinical isolates.

Plos One
Baatz, Franky F; Nijhuis, Monique M; Lemaire, Morgane M; Riedijk, Martiene M; Wensing, Annemarie M J AM; Servais, Jean-Yves JY; van Ham, Petra M PM; Hoepelman, Andy I M AI; Koopmans, Peter P PP; Sprenger, Herman G HG; Devaux, Carole C; Schmit, Jean-Claude JC; Perez Bercoff, Danielle D
Publication Date: 2011

Variant appearance in text: CD4: S138A
PubMed Link: 21760896
Variant Present in the following documents:
  • Main text
  • pone.0021535.pdf
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HR-2 mutations in human immunodeficiency virus type 1 gp41 restore fusion kinetics delayed by HR-1 mutations that cause clinical resistance to enfuvirtide.

Journal Of Virology
Ray, Neelanjana N; Blackburn, Leslie A LA; Doms, Robert W RW
Publication Date: 2009-04

Variant appearance in text: CD4: S138A
PubMed Link: 19153234
Variant Present in the following documents:
  • Main text
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SC29EK, a peptide fusion inhibitor with enhanced alpha-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide.

Antimicrobial Agents And Chemotherapy
Naito, Takeshi T; Izumi, Kazuki K; Kodama, Eiichi E; Sakagami, Yasuko Y; Kajiwara, Keiko K; Nishikawa, Hiroki H; Watanabe, Kentaro K; Sarafianos, Stefan G SG; Oishi, Shinya S; Fujii, Nobutaka N; Matsuoka, Masao M
Publication Date: 2009-03

Variant appearance in text: CD4: S138A
PubMed Link: 19114674
Variant Present in the following documents:
  • Main text
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Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20.

The Journal Of Biological Chemistry
Izumi, Kazuki K; Kodama, Eiichi E; Shimura, Kazuya K; Sakagami, Yasuko Y; Watanabe, Kentaro K; Ito, Saori S; Watabe, Tsuyoshi T; Terakawa, Yukihiro Y; Nishikawa, Hiroki H; Sarafianos, Stefan G SG; Kitaura, Kazuo K; Oishi, Shinya S; Fujii, Nobutaka N; Matsuoka, Masao M
Publication Date: 2009-02-20

Variant appearance in text: CD4: S138A
PubMed Link: 19073606
Variant Present in the following documents:
  • Main text
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Selection of T1249-resistant human immunodeficiency virus type 1 variants.

Journal Of Virology
Eggink, Dirk D; Baldwin, Christopher E CE; Deng, Yiqun Y; Langedijk, Johannes P M JP; Lu, Min M; Sanders, Rogier W RW; Berkhout, Ben B
Publication Date: 2008-07

Variant appearance in text: CD4: S138A
PubMed Link: 18434391
Variant Present in the following documents:
  • Main text
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HIV-1 drug-resistance and drug-dependence.

Retrovirology
Baldwin, Chris C; Berkhout, Ben B
Publication Date: 2007-10-25

Variant appearance in text: CD4: S138A
PubMed Link: 17961213
Variant Present in the following documents:
  • Main text
  • 1742-4690-4-78.pdf
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Clinical resistance to enfuvirtide does not affect susceptibility of human immunodeficiency virus type 1 to other classes of entry inhibitors.

Journal Of Virology
Ray, Neelanjana N; Harrison, Jessamina E JE; Blackburn, Leslie A LA; Martin, Jeffrey N JN; Deeks, Steven G SG; Doms, Robert W RW
Publication Date: 2007-04

Variant appearance in text: CD4: S138A
PubMed Link: 17251281
Variant Present in the following documents:
  • Main text
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Impact of human immunodeficiency virus type 1 gp41 amino acid substitutions selected during enfuvirtide treatment on gp41 binding and antiviral potency of enfuvirtide in vitro.

Journal Of Virology
Mink, M M; Mosier, S M SM; Janumpalli, S S; Davison, D D; Jin, L L; Melby, T T; Sista, P P; Erickson, J J; Lambert, D D; Stanfield-Oakley, S A SA; Salgo, M M; Cammack, N N; Matthews, T T; Greenberg, M L ML
Publication Date: 2005-10

Variant appearance in text: CD4: S138A
PubMed Link: 16160172
Variant Present in the following documents:
  • Main text
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Emergence and evolution of enfuvirtide resistance following long-term therapy involves heptad repeat 2 mutations within gp41.

Antimicrobial Agents And Chemotherapy
Xu, L L; Pozniak, A A; Wildfire, A A; Stanfield-Oakley, S A SA; Mosier, S M SM; Ratcliffe, D D; Workman, J J; Joall, A A; Myers, R R; Smit, E E; Cane, P A PA; Greenberg, M L ML; Pillay, D D
Publication Date: 2005-03

Variant appearance in text: CD4: S138A
PubMed Link: 15728911
Variant Present in the following documents:
  • Main text
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Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment.

Antimicrobial Agents And Chemotherapy
Menzo, Stefano S; Castagna, Antonella A; Monachetti, Alessia A; Hasson, Hamid H; Danise, Anna A; Carini, Elisabetta E; Bagnarelli, Patrizia P; Lazzarin, Adriano A; Clementi, Massimo M
Publication Date: 2004-09

Variant appearance in text: CD4: S138A
PubMed Link: 15328081
Variant Present in the following documents:
  • Main text
View BVdb publication page