Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.
The Embo Journal
Matheny, Christina J CJ; Speck, Maren E ME; Cushing, Patrick R PR; Zhou, Yunpeng Y; Corpora, Takeshi T; Regan, Michael M; Newman, Miki M; Roudaia, Liya L; Speck, Caroline L CL; Gu, Ting-Lei TL; Griffey, Stephen M SM; Bushweller, John H JH; Speck, Nancy A NA