CD4 c.707G>C ;(p.G236A)

Variant ID: 12-6925321-G-C

NM_000616.4(CD4):c.707G>C;(p.G236A)

This variant was identified in 21 publications

View GRCh38 version.




Publications:


Therapeutic strategies for COVID-19: progress and lessons learned.

Nature Reviews. Drug Discovery
Li, Guangdi G; Hilgenfeld, Rolf R; Whitley, Richard R; De Clercq, Erik E
Publication Date: 2023-04-19

Variant appearance in text: CD4: G236A
PubMed Link: 37076602
Variant Present in the following documents:
  • Main text
View BVdb publication page



HIV-1 Vpu restricts Fc-mediated effector functions in vivo.

Cell Reports
Prévost, Jérémie J; Anand, Sai Priya SP; Rajashekar, Jyothi Krishnaswamy JK; Zhu, Li L; Richard, Jonathan J; Goyette, Guillaume G; Medjahed, Halima H; Gendron-Lepage, Gabrielle G; Chen, Hung-Ching HC; Chen, Yaozong Y; Horwitz, Joshua A JA; Grunst, Michael W MW; Zolla-Pazner, Susan S; Haynes, Barton F BF; Burton, Dennis R DR; Flavell, Richard A RA; Kirchhoff, Frank F; Hahn, Beatrice H BH; Smith, Amos B AB; Pazgier, Marzena M; Nussenzweig, Michel C MC; Kumar, Priti P; Finzi, Andrés A
Publication Date: 2022-11-08

Variant appearance in text: CD4: G236A
PubMed Link: 36351384
Variant Present in the following documents:
  • Main text
  • nihms-1848911.pdf
View BVdb publication page



Monoclonal antibody therapies against SARS-CoV-2.

The Lancet. Infectious Diseases
Focosi, Daniele D; McConnell, Scott S; Casadevall, Arturo A; Cappello, Emiliano E; Valdiserra, Giulia G; Tuccori, Marco M
Publication Date: 2022-11

Variant appearance in text: CD4: G236A
PubMed Link: 35803289
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Antibodies to combat viral infections: development strategies and progress.

Nature Reviews. Drug Discovery
Pantaleo, Giuseppe G; Correia, Bruno B; Fenwick, Craig C; Joo, Victor S VS; Perez, Laurent L
Publication Date: 2022-09

Variant appearance in text: CD4: G236A
PubMed Link: 35725925
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis.

Nature Communications
Spencer, David A DA; Goldberg, Benjamin S BS; Pandey, Shilpi S; Ordonez, Tracy T; Dufloo, Jérémy J; Barnette, Philip P; Sutton, William F WF; Henderson, Heidi H; Agnor, Rebecca R; Gao, Lina L; Bruel, Timothée T; Schwartz, Olivier O; Haigwood, Nancy L NL; Ackerman, Margaret E ME; Hessell, Ann J AJ
Publication Date: 2022-02-03

Variant appearance in text: CD4: G236A
PubMed Link: 35115533
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_28250.pdf
View BVdb publication page



Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis.

Nature Communications
Spencer, David A DA; Goldberg, Benjamin S BS; Pandey, Shilpi S; Ordonez, Tracy T; Dufloo, Jérémy J; Barnette, Philip P; Sutton, William F WF; Henderson, Heidi H; Agnor, Rebecca R; Gao, Lina L; Bruel, Timothée T; Schwartz, Olivier O; Haigwood, Nancy L NL; Ackerman, Margaret E ME; Hessell, Ann J AJ
Publication Date: 2022-02-03

Variant appearance in text: CD4: G236A
PubMed Link: 35115533
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_28250.pdf
View BVdb publication page



Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.

Cell Reports
Li, Wenwei W; Chen, Yaozong Y; Prévost, Jérémie J; Ullah, Irfan I; Lu, Maolin M; Gong, Shang Yu SY; Tauzin, Alexandra A; Gasser, Romain R; Vézina, Dani D; Anand, Sai Priya SP; Goyette, Guillaume G; Chaterjee, Debashree D; Ding, Shilei S; Tolbert, William D WD; Grunst, Michael W MW; Bo, Yuxia Y; Zhang, Shijian S; Richard, Jonathan J; Zhou, Fei F; Huang, Rick K RK; Esser, Lothar L; Zeher, Allison A; Côté, Marceline M; Kumar, Priti P; Sodroski, Joseph J; Xia, Di D; Uchil, Pradeep D PD; Pazgier, Marzena M; Finzi, Andrés A; Mothes, Walther W
Publication Date: 2021-12-15

Variant appearance in text: CD4: G236A
PubMed Link: 34971573
Variant Present in the following documents:
  • Main text
  • mmc4.pdf
  • main.pdf
View BVdb publication page



Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.

Cell Reports
Li, Wenwei W; Chen, Yaozong Y; Prévost, Jérémie J; Ullah, Irfan I; Lu, Maolin M; Gong, Shang Yu SY; Tauzin, Alexandra A; Gasser, Romain R; Vézina, Dani D; Anand, Sai Priya SP; Goyette, Guillaume G; Chaterjee, Debashree D; Ding, Shilei S; Tolbert, William D WD; Grunst, Michael W MW; Bo, Yuxia Y; Zhang, Shijian S; Richard, Jonathan J; Zhou, Fei F; Huang, Rick K RK; Esser, Lothar L; Zeher, Allison A; Côté, Marceline M; Kumar, Priti P; Sodroski, Joseph J; Xia, Di D; Uchil, Pradeep D PD; Pazgier, Marzena M; Finzi, Andrés A; Mothes, Walther W
Publication Date: 2022-01-11

Variant appearance in text: CD4: G236A
PubMed Link: 34971573
Variant Present in the following documents:
  • Main text
  • mmc4.pdf
  • main.pdf
View BVdb publication page



The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies.

International Journal Of Molecular Sciences
Gogesch, Patricia P; Dudek, Simone S; van Zandbergen, Ger G; Waibler, Zoe Z; Anzaghe, Martina M
Publication Date: 2021-08-19

Variant appearance in text: CD4: Gly236Ala
PubMed Link: 34445651
Variant Present in the following documents:
  • ijms-22-08947.pdf
View BVdb publication page



Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern.

Biorxiv : The Preprint Server For Biology
Li, Wenwei W; Chen, Yaozong Y; Prévost, Jérémie J; Ullah, Irfan I; Lu, Maolin M; Gong, Shang Yu SY; Tauzin, Alexandra A; Gasser, Romain R; Vézina, Dani D; Anand, Sai Priya SP; Goyette, Guillaume G; Chaterjee, Debashree D; Ding, Shilei S; Tolbert, William D WD; Grunst, Michael W MW; Bo, Yuxia Y; Zhang, Shijian S; Richard, Jonathan J; Zhou, Fei F; Huang, Rick K RK; Esser, Lothar L; Zeher, Allison A; Côté, Marceline M; Kumar, Priti P; Sodroski, Joseph J; Xia, Di D; Uchil, Pradeep D PD; Pazgier, Marzena M; Finzi, Andrés A; Mothes, Walther W
Publication Date: 2021-08-03

Variant appearance in text: CD4: G236A
PubMed Link: 34373853
Variant Present in the following documents:
  • Main text
View BVdb publication page



Broadly Neutralizing Antibodies for HIV-1 Prevention.

Frontiers In Immunology
Walsh, Stephen R SR; Seaman, Michael S MS
Publication Date: 2021

Variant appearance in text: CD4: G236A
PubMed Link: 34354713
Variant Present in the following documents:
  • Main text
  • fimmu-12-712122.pdf
View BVdb publication page



Development of Therapeutic Antibodies and Modulating the Characteristics of Therapeutic Antibodies to Maximize the Therapeutic Efficacy.

Biotechnology And Bioprocess Engineering : Bbe
Kang, Seung Hyun SH; Lee, Chang-Han CH
Publication Date: 2021

Variant appearance in text: CD4: G236A
PubMed Link: 34220207
Variant Present in the following documents:
  • 12257_2020_Article_181.pdf
View BVdb publication page



Advancing HIV Broadly Neutralizing Antibodies: From Discovery to the Clinic.

Frontiers In Public Health
Spencer, David A DA; Shapiro, Mariya B MB; Haigwood, Nancy L NL; Hessell, Ann J AJ
Publication Date: 2021

Variant appearance in text: CD4: G236A
PubMed Link: 34123998
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tackling COVID-19 with neutralizing monoclonal antibodies.

Cell
Corti, Davide D; Purcell, Lisa A LA; Snell, Gyorgy G; Veesler, David D
Publication Date: 2021-06-10

Variant appearance in text: CD4: G236A
PubMed Link: 34087172
Variant Present in the following documents:
  • Main text
View BVdb publication page



Enhancement of Antibody-Dependent Cellular Cytotoxicity and Phagocytosis in Anti-HIV-1 Human-Bovine Chimeric Broadly Neutralizing Antibodies.

Journal Of Virology
Edwards, Jack M JM; Heydarchi, Behnaz B; Khoury, Georges G; Salazar-Quiroz, Natalia A NA; Gonelli, Christopher A CA; Wines, Bruce B; Hogarth, P Mark PM; Kristensen, Anne B AB; Parsons, Matthew S MS; Purcell, Damian F J DFJ
Publication Date: 2021-06-10

Variant appearance in text: CD4: G236A
PubMed Link: 33853957
Variant Present in the following documents:
  • Main text
View BVdb publication page



Antibodies for Human Immunodeficiency Virus-1 Cure Strategies.

The Journal Of Infectious Diseases
Rossignol, Evan E; Alter, Galit G; Julg, Boris B
Publication Date: 2021-02-15

Variant appearance in text: CD4: G236A
PubMed Link: 33586772
Variant Present in the following documents:
  • Main text
View BVdb publication page



The role of IgG Fc receptors in antibody-dependent enhancement.

Nature Reviews. Immunology
Bournazos, Stylianos S; Gupta, Aaron A; Ravetch, Jeffrey V JV
Publication Date: 2020-10

Variant appearance in text: CD4: G236A
PubMed Link: 32782358
Variant Present in the following documents:
  • Main text
View BVdb publication page



Roles of fragment crystallizable-mediated effector functions in broadly neutralizing antibody activity against HIV.

Current Opinion In Hiv And Aids
Danesh, Ali A; Ren, Yanqin Y; Brad Jones, R R
Publication Date: 2020-09

Variant appearance in text: CD4: G236A
PubMed Link: 32732552
Variant Present in the following documents:
  • Main text
View BVdb publication page



convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting.

Communications Biology
Landgraf, Kyle E KE; Williams, Steven R SR; Steiger, Daniel D; Gebhart, Dana D; Lok, Stephen S; Martin, David W DW; Roybal, Kole T KT; Kim, Kaman Chan KC
Publication Date: 2020-06-09

Variant appearance in text: CD4: G236A
PubMed Link: 32518350
Variant Present in the following documents:
  • 42003_2020_Article_1021.pdf
View BVdb publication page



FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Borghi, Sara S; Bournazos, Stylianos S; Thulin, Natalie K NK; Li, Chao C; Gajewski, Anna A; Sherwood, Robert W RW; Zhang, Sheng S; Harris, Eva E; Jagannathan, Prasanna P; Wang, Lai-Xi LX; Ravetch, Jeffrey V JV; Wang, Taia T TT
Publication Date: 2020-06-09

Variant appearance in text: CD4: G236A
PubMed Link: 32461366
Variant Present in the following documents:
  • Main text
View BVdb publication page



Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections.

Vaccines
Anand, Sai Priya SP; Finzi, Andrés A
Publication Date: 2019-08-30

Variant appearance in text: CD4: G236A
PubMed Link: 31480293
Variant Present in the following documents:
  • Main text
  • vaccines-07-00103.pdf
View BVdb publication page



Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect.

Cell
DiLillo, David J DJ; Ravetch, Jeffrey V JV
Publication Date: 2015-05-21

Variant appearance in text: CD4: G236A
PubMed Link: 25976835
Variant Present in the following documents:
  • Main text
View BVdb publication page



Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.

Aids Research And Human Retroviruses
Euler, Zelda Z; Alter, Galit G
Publication Date: 2015-01

Variant appearance in text: CD4: G236A
PubMed Link: 25385703
Variant Present in the following documents:
  • Main text
View BVdb publication page