Week 96 Genotypic and Phenotypic Results of the Fostemsavir Phase 3 BRIGHTE Study in Heavily Treatment-Experienced Adults Living with Multidrug-Resistant HIV-1.
Antimicrobial Agents And Chemotherapy
Gartland, Margaret M; Cahn, Pedro P; DeJesus, Edwin E; Diaz, Ricardo Sobhie RS; Grossberg, Robert R; Kozal, Michael M; Kumar, Princy P; Molina, Jean-Michel JM; Mendo Urbina, Fernando F; Wang, Marcia M; Du, Fangfang F; Chabria, Shiven S; Clark, Andrew A; Garside, Louise L; Krystal, Mark M; Mannino, Frank F; Pierce, Amy A; Ackerman, Peter P; Lataillade, Max M
mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.
Oncogene
Luiken, Sarah S; Fraas, Angelika A; Bieg, Matthias M; Sugiyanto, Raisatun R; Goeppert, Benjamin B; Singer, Stephan S; Ploeger, Carolin C; Warsow, Gregor G; Marquardt, Jens U JU; Sticht, Carsten C; De La Torre, Carolina C; Pusch, Stefan S; Mehrabi, Arianeb A; Gretz, Norbert N; Schlesner, Matthias M; Eils, Roland R; Schirmacher, Peter P; Longerich, Thomas T; Roessler, Stephanie S
Publication Date: 2020-04
Variant appearance in text: CD4: S375S; rs782556070
MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency.
Retrovirology
Grupping, Katrijn K; Selhorst, Philippe P; Michiels, Johan J; Vereecken, Katleen K; Heyndrickx, Leo L; Kessler, Pascal P; Vanham, Guido G; Martin, Loïc L; Ariën, Kevin K KK
Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity.
Journal Of Virology
Dey, Barna B; Pancera, Marie M; Svehla, Krisha K; Shu, Yuuei Y; Xiang, Shi-Hua SH; Vainshtein, Jeffrey J; Li, Yuxing Y; Sodroski, Joseph J; Kwong, Peter D PD; Mascola, John R JR; Wyatt, Richard R