CD4 c.1125G>A ;(p.S375=)

Variant ID: 12-6926465-G-A

NM_000616.4(CD4):c.1125G>A;(p.S375=)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Week 96 Genotypic and Phenotypic Results of the Fostemsavir Phase 3 BRIGHTE Study in Heavily Treatment-Experienced Adults Living with Multidrug-Resistant HIV-1.

Antimicrobial Agents And Chemotherapy
Gartland, Margaret M; Cahn, Pedro P; DeJesus, Edwin E; Diaz, Ricardo Sobhie RS; Grossberg, Robert R; Kozal, Michael M; Kumar, Princy P; Molina, Jean-Michel JM; Mendo Urbina, Fernando F; Wang, Marcia M; Du, Fangfang F; Chabria, Shiven S; Clark, Andrew A; Garside, Louise L; Krystal, Mark M; Mannino, Frank F; Pierce, Amy A; Ackerman, Peter P; Lataillade, Max M
Publication Date: 2022-06-21

Variant appearance in text: CD4: S375S
PubMed Link: 35502922
Variant Present in the following documents:
  • Main text
  • aac.01751-21.pdf
View BVdb publication page



mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
Publication Date: 2020-06-23

Variant appearance in text: CD4: S375S
PubMed Link: 32579932
Variant Present in the following documents:
  • mmc5.xlsx, sheet 3
View BVdb publication page



NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.

Oncogene
Luiken, Sarah S; Fraas, Angelika A; Bieg, Matthias M; Sugiyanto, Raisatun R; Goeppert, Benjamin B; Singer, Stephan S; Ploeger, Carolin C; Warsow, Gregor G; Marquardt, Jens U JU; Sticht, Carsten C; De La Torre, Carolina C; Pusch, Stefan S; Mehrabi, Arianeb A; Gretz, Norbert N; Schlesner, Matthias M; Eils, Roland R; Schirmacher, Peter P; Longerich, Thomas T; Roessler, Stephanie S
Publication Date: 2020-04

Variant appearance in text: CD4: S375S; rs782556070
PubMed Link: 32055024
Variant Present in the following documents:
  • 41388_2020_1198_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Viral Drug Resistance Through 48 Weeks, in a Phase 2b, Randomized, Controlled Trial of the HIV-1 Attachment Inhibitor Prodrug, Fostemsavir.

Journal Of Acquired Immune Deficiency Syndromes (1999)
Lataillade, Max M; Zhou, Nannan N; Joshi, Samit R SR; Lee, Sangil S; Stock, David A DA; Hanna, George J GJ; Krystal, Mark M; ,
Publication Date: 2018-03-01

Variant appearance in text: CD4: S375S
PubMed Link: 29206721
Variant Present in the following documents:
  • Main text
  • qai-77-299.pdf
View BVdb publication page



MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency.

Retrovirology
Grupping, Katrijn K; Selhorst, Philippe P; Michiels, Johan J; Vereecken, Katleen K; Heyndrickx, Leo L; Kessler, Pascal P; Vanham, Guido G; Martin, Loïc L; Ariën, Kevin K KK
Publication Date: 2012-05-02

Variant appearance in text: CD4: S375S
PubMed Link: 22551420
Variant Present in the following documents:
  • 1742-4690-9-36.pdf
View BVdb publication page



Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity.

Journal Of Virology
Dey, Barna B; Pancera, Marie M; Svehla, Krisha K; Shu, Yuuei Y; Xiang, Shi-Hua SH; Vainshtein, Jeffrey J; Li, Yuxing Y; Sodroski, Joseph J; Kwong, Peter D PD; Mascola, John R JR; Wyatt, Richard R
Publication Date: 2007-06

Variant appearance in text: CD4: S375S
PubMed Link: 17360741
Variant Present in the following documents:
  • Main text
View BVdb publication page