Publications:

Sequences in glycoprotein gp41, the CD4 binding site, and the V2 domain regulate sensitivity and resistance of HIV-1 to broadly neutralizing antibodies.

Journal Of Virology

O'Rourke, Sara M SM; Schweighardt, Becky B; Phung, Pham P; Mesa, Kathryn A KA; Vollrath, Aaron L AL; Tatsuno, Gwen P GP; To, Briana B; Sinangil, Faruk F; Limoli, Kay K; Wrin, Terri T; Berman, Phillip W PW

Publication Date: 2012-11

Variant appearance in text: CD4: S440R

PubMed Link: 22933284

Variant Present in the following documents:

• Main text

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In vivo patterns of resistance to the HIV attachment inhibitor BMS-488043.

Antimicrobial Agents And Chemotherapy

Zhou, Nannan N; Nowicka-Sans, Beata B; Zhang, Sharon S; Fan, Li L; Fang, Jie J; Fang, Hua H; Gong, Yi-Fei YF; Eggers, Betsy B; Langley, David R DR; Wang, Tao T; Kadow, John J; Grasela, Dennis D; Hanna, George J GJ; Alexander, Louis L; Colonno, Richard R; Krystal, Mark M; Lin, Pin-Fang PF

Publication Date: 2011-02

Variant appearance in text: CD4: S440R

PubMed Link: 21078948

Variant Present in the following documents:

• Main text

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Human immunodeficiency virus type 1 escape from cyclotriazadisulfonamide-induced CD4-targeted entry inhibition is associated with increased neutralizing antibody susceptibility.

Journal Of Virology

Vermeire, Kurt K; Van Laethem, Kristel K; Janssens, Wouter W; Bell, Thomas W TW; Schols, Dominique D

Publication Date: 2009-09

Variant appearance in text: CD4: S440R

PubMed Link: 19570853

Variant Present in the following documents:

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Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions.

Journal Of Virology

Guo, Qi Q; Ho, Hsu-Tso HT; Dicker, Ira I; Fan, Li L; Zhou, Nannan N; Friborg, Jacques J; Wang, Tao T; McAuliffe, Brian V BV; Wang, Hwei-Gene Heidi HG; Rose, Ronald E RE; Fang, Hua H; Scarnati, Helen T HT; Langley, David R DR; Meanwell, Nicholas A NA; Abraham, Ralph R; Colonno, Richard J RJ; Lin, Pin-Fang PF

Publication Date: 2003-10

Variant appearance in text: CD4: S440R

PubMed Link: 12970437

Variant Present in the following documents:

• Main text

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A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Lin, Pin-Fang PF; Blair, Wade W; Wang, Tao T; Spicer, Timothy T; Guo, Qi Q; Zhou, Nannan N; Gong, Yi-Fei YF; Wang, H-G Heidi HG; Rose, Ronald R; Yamanaka, Gregory G; Robinson, Brett B; Li, Chang-Ben CB; Fridell, Robert R; Deminie, Carol C; Demers, Gwendeline G; Yang, Zheng Z; Zadjura, Lisa L; Meanwell, Nicholas N; Colonno, Richard R

Publication Date: 2003-09-16

Variant appearance in text: CD4: S440R

PubMed Link: 12930892

Variant Present in the following documents:

• Main text

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