APAF1 c.479A>G ;(p.K160R)

Variant ID: 12-99043415-A-G

NM_181861.1(APAF1):c.479A>G;(p.K160R)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Apoptosome Formation through Disruption of the K192-D616 Salt Bridge in the Apaf-1 Closed Form.

Acs Omega
Sahebazzamani, Fatemeh F; Hosseinkhani, Saman S; Eriksson, Leif A LA; Fearnhead, Howard O HO
Publication Date: 2021-09-07

Variant appearance in text: APAF-1: K160R
PubMed Link: 34514227
Variant Present in the following documents:
  • Main text
  • ao1c02274.pdf
View BVdb publication page



The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities.

Nature Communications
Wu, Chu-Chiao CC; Lee, Sunhee S; Malladi, Srinivas S; Chen, Miao-Der MD; Mastrandrea, Nicholas J NJ; Zhang, Zhiwen Z; Bratton, Shawn B SB
Publication Date: 2016-11-24

Variant appearance in text: APAF-1: K160R
PubMed Link: 27882936
Variant Present in the following documents:
  • ncomms13565.pdf
View BVdb publication page