The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.
Frontiers In Pharmacology
Trompet, Stella S; Postmus, Iris I; Warren, Helen R HR; Noordam, Raymond R; Smit, Roelof A J RAJ; Theusch, Elizabeth E; Li, Xiaohui X; Arsenault, Benoit B; Chasman, Daniel I DI; Hitman, Graham A GA; Munroe, Patricia B PB; Rotter, Jerome I JI; Psaty, Bruce M BM; Caulfield, Mark J MJ; Krauss, Ron M RM; Cupples, Adrienne L AL; Jukema, Wouter J WJ
Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing.
Circulation. Genomic And Precision Medicine
Carss, Keren J KJ; Baranowska, Anna A AA; Armisen, Javier J; Webb, Tom R TR; Hamby, Stephen E SE; Premawardhana, Diluka D; Al-Hussaini, Abtehale A; Wood, Alice A; Wang, Quanli Q; Deevi, Sri V V SVV; Vitsios, Dimitrios D; Lewis, Samuel H SH; Kotecha, Deevia D; Bouatia-Naji, Nabila N; Hesselson, Stephanie S; Iismaa, Siiri E SE; Tarr, Ingrid I; McGrath-Cadell, Lucy L; Muller, David W DW; Dunwoodie, Sally L SL; Fatkin, Diane D; Graham, Robert M RM; Giannoulatou, Eleni E; Samani, Nilesh J NJ; Petrovski, Slavé S; Haefliger, Carolina C; Adlam, David D
Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies.
Scientific Reports
Shadrina, Alexandra S AS; Shashkova, Tatiana I TI; Torgasheva, Anna A AA; Sharapov, Sodbo Z SZ; Klarić, Lucija L; Pakhomov, Eugene D ED; Alexeev, Dmitry G DG; Wilson, James F JF; Tsepilov, Yakov A YA; Joshi, Peter K PK; Aulchenko, Yurii S YS
Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease.
Arteriosclerosis, Thrombosis, And Vascular Biology
Veluchamy, Abirami A; Ballerini, Lucia L; Vitart, Veronique V; Schraut, Katharina E KE; Kirin, Mirna M; Campbell, Harry H; Joshi, Peter K PK; Relan, Devanjali D; Harris, Sarah S; Brown, Ellie E; Vaidya, Suraj S SS; Dhillon, Baljean B; Zhou, Kaixin K; Pearson, Ewan R ER; Hayward, Caroline C; Polasek, Ozren O; Deary, Ian J IJ; MacGillivray, Thomas T; Wilson, James F JF; Trucco, Emanuele E; Palmer, Colin N A CNA; Doney, Alexander S F ASF
Activation of immune responses against the basement membrane component collagen type IV does not affect the development of atherosclerosis in ApoE-deficient mice.
Scientific Reports
Vallejo, J J; Dunér, P P; To, F F; Engelbertsen, D D; Gonçalves, I I; Nilsson, J J; Bengtsson, E E
Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.
Cardiovascular Diabetology
Charmet, Romain R; Duffy, Seamus S; Keshavarzi, Sareh S; Gyorgy, Beata B; Marre, Michel M; Rossing, Peter P; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Ahluwalia, Tarun Veer Singh TVS; Paterson, Andrew D AD; Trégouët, David-Alexandre DA; Hadjadj, Samy S
Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study.
Frontiers In Cardiovascular Medicine
Knowles, Joshua W JW; Zarafshar, Shirin S; Pavlovic, Aleksandra A; Goldstein, Benjamin A BA; Tsai, Sandra S; Li, Jin J; McConnell, Michael V MV; Absher, Devin D; Ashley, Euan A EA; Kiernan, Michaela M; Ioannidis, John P A JPA; Assimes, Themistocles L TL
Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons.
Scientific Reports
Hixson, James E JE; Jun, Goo G; Shimmin, Lawrence C LC; Wang, Yizhi Y; Yu, Guoqiang G; Mao, Chunhong C; Warren, Andrew S AS; Howard, Timothy D TD; Heide, Richard S Vander RSV; Van Eyk, Jennifer J; Wang, Yue Y; Herrington, David M DM
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Nature Genetics
Howson, Joanna M M JMM; Zhao, Wei W; Barnes, Daniel R DR; Ho, Weang-Kee WK; Young, Robin R; Paul, Dirk S DS; Waite, Lindsay L LL; Freitag, Daniel F DF; Fauman, Eric B EB; Salfati, Elias L EL; Sun, Benjamin B BB; Eicher, John D JD; Johnson, Andrew D AD; Sheu, Wayne H H WHH; Nielsen, Sune F SF; Lin, Wei-Yu WY; Surendran, Praveen P; Malarstig, Anders A; Wilk, Jemma B JB; Tybjærg-Hansen, Anne A; Rasmussen, Katrine L KL; Kamstrup, Pia R PR; Deloukas, Panos P; Erdmann, Jeanette J; Kathiresan, Sekar S; Samani, Nilesh J NJ; Schunkert, Heribert H; Watkins, Hugh H; , ; Do, Ron R; Rader, Daniel J DJ; Johnson, Julie A JA; Hazen, Stanley L SL; Quyyumi, Arshed A AA; Spertus, John A JA; Pepine, Carl J CJ; Franceschini, Nora N; Justice, Anne A; Reiner, Alex P AP; Buyske, Steven S; Hindorff, Lucia A LA; Carty, Cara L CL; North, Kari E KE; Kooperberg, Charles C; Boerwinkle, Eric E; Young, Kristin K; Graff, Mariaelisa M; Peters, Ulrike U; Absher, Devin D; Hsiung, Chao A CA; Lee, Wen-Jane WJ; Taylor, Kent D KD; Chen, Ying-Hsiang YH; Lee, I-Te IT; Guo, Xiuqing X; Chung, Ren-Hua RH; Hung, Yi-Jen YJ; Rotter, Jerome I JI; Juang, Jyh-Ming J JJ; Quertermous, Thomas T; Wang, Tzung-Dau TD; Rasheed, Asif A; Frossard, Philippe P; Alam, Dewan S DS; Majumder, Abdulla Al Shafi AAS; Di Angelantonio, Emanuele E; Chowdhury, Rajiv R; , ; Chen, Yii-Der Ida YI; Nordestgaard, Børge G BG; Assimes, Themistocles L TL; Danesh, John J; Butterworth, Adam S AS; Saleheen, Danish D
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.
Circulation
Benjamin, Emelia J EJ; Blaha, Michael J MJ; Chiuve, Stephanie E SE; Cushman, Mary M; Das, Sandeep R SR; Deo, Rajat R; de Ferranti, Sarah D SD; Floyd, James J; Fornage, Myriam M; Gillespie, Cathleen C; Isasi, Carmen R CR; Jiménez, Monik C MC; Jordan, Lori Chaffin LC; Judd, Suzanne E SE; Lackland, Daniel D; Lichtman, Judith H JH; Lisabeth, Lynda L; Liu, Simin S; Longenecker, Chris T CT; Mackey, Rachel H RH; Matsushita, Kunihiro K; Mozaffarian, Dariush D; Mussolino, Michael E ME; Nasir, Khurram K; Neumar, Robert W RW; Palaniappan, Latha L; Pandey, Dilip K DK; Thiagarajan, Ravi R RR; Reeves, Mathew J MJ; Ritchey, Matthew M; Rodriguez, Carlos J CJ; Roth, Gregory A GA; Rosamond, Wayne D WD; Sasson, Comilla C; Towfighi, Amytis A; Tsao, Connie W CW; Turner, Melanie B MB; Virani, Salim S SS; Voeks, Jenifer H JH; Willey, Joshua Z JZ; Wilkins, John T JT; Wu, Jason Hy JH; Alger, Heather M HM; Wong, Sally S SS; Muntner, Paul P; ,
Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.
Arthritis & Rheumatology (Hoboken, N.J.)
Ferraz-Amaro, Iván I; Winchester, Robert R; Gregersen, Peter K PK; Reynolds, Richard J RJ; Wasko, Mary Chester MC; Oeser, Anette A; Chung, Cecilia P CP; Stein, C Michael CM; Giles, Jon T JT; Bathon, Joan M JM
Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction.
Plos Genetics
Yang, Wei W; Ng, Fu Liang FL; Chan, Kenneth K; Pu, Xiangyuan X; Poston, Robin N RN; Ren, Meixia M; An, Weiwei W; Zhang, Ruoxin R; Wu, Jingchun J; Yan, Shunying S; Situ, Haiteng H; He, Xinjie X; Chen, Yequn Y; Tan, Xuerui X; Xiao, Qingzhong Q; Tucker, Arthur T AT; Caulfield, Mark J MJ; Ye, Shu S
Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.
Data In Brief
Vargas, Jose D JD; Manichaikul, Ani A; Wang, Xin-Qun XQ; Rich, Stephen S SS; Rotter, Jerome I JI; Post, Wendy S WS; Polak, Joseph F JF; Budoff, Matthew J MJ; Bluemke, David A DA
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.
Plos One
Dehghan, Abbas A; Bis, Joshua C JC; White, Charles C CC; Smith, Albert Vernon AV; Morrison, Alanna C AC; Cupples, L Adrienne LA; Trompet, Stella S; Chasman, Daniel I DI; Lumley, Thomas T; Völker, Uwe U; Buckley, Brendan M BM; Ding, Jingzhong J; Jensen, Majken K MK; Folsom, Aaron R AR; Kritchevsky, Stephen B SB; Girman, Cynthia J CJ; Ford, Ian I; Dörr, Marcus M; Salomaa, Veikko V; Uitterlinden, André G AG; Eiriksdottir, Gudny G; Vasan, Ramachandran S RS; Franceschini, Nora N; Carty, Cara L CL; Virtamo, Jarmo J; Demissie, Serkalem S; Amouyel, Philippe P; Arveiler, Dominique D; Heckbert, Susan R SR; Ferrières, Jean J; Ducimetière, Pierre P; Smith, Nicholas L NL; Wang, Ying A YA; Siscovick, David S DS; Rice, Kenneth M KM; Wiklund, Per-Gunnar PG; Taylor, Kent D KD; Evans, Alun A; Kee, Frank F; Rotter, Jerome I JI; Karvanen, Juha J; Kuulasmaa, Kari K; Heiss, Gerardo G; Kraft, Peter P; Launer, Lenore J LJ; Hofman, Albert A; Markus, Marcello R P MR; Rose, Lynda M LM; Silander, Kaisa K; Wagner, Peter P; Benjamin, Emelia J EJ; Lohman, Kurt K; Stott, David J DJ; Rivadeneira, Fernando F; Harris, Tamara B TB; Levy, Daniel D; Liu, Yongmei Y; Rimm, Eric B EB; Jukema, J Wouter JW; Völzke, Henry H; Ridker, Paul M PM; Blankenberg, Stefan S; Franco, Oscar H OH; Gudnason, Vilmundur V; Psaty, Bruce M BM; Boerwinkle, Eric E; O'Donnell, Christopher J CJ
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
Lancet (London, England)
Mega, J L JL; Stitziel, N O NO; Smith, J G JG; Chasman, D I DI; Caulfield, M M; Devlin, J J JJ; Nordio, F F; Hyde, C C; Cannon, C P CP; Sacks, F F; Poulter, N N; Sever, P P; Ridker, P M PM; Braunwald, E E; Melander, O O; Kathiresan, S S; Sabatine, M S MS
Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.
Plos One
Franceschini, Nora N; Hu, Yijuan Y; Reiner, Alex P AP; Buyske, Steven S; Nalls, Mike M; Yanek, Lisa R LR; Li, Yun Y; Hindorff, Lucia A LA; Cole, Shelley A SA; Howard, Barbara V BV; Stafford, Jeanette M JM; Carty, Cara L CL; Sethupathy, Praveen P; Martin, Lisa W LW; Lin, Dan-Yu DY; Johnson, Karen C KC; Becker, Lewis C LC; North, Kari E KE; Dehghan, Abbas A; Bis, Joshua C JC; Liu, Yongmei Y; Greenland, Philip P; Manson, JoAnn E JE; Maeda, Nobuyo N; Garcia, Melissa M; Harris, Tamara B TB; Becker, Diane M DM; O'Donnell, Christopher C; Heiss, Gerardo G; Kooperberg, Charles C; Boerwinkle, Eric E
Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach.
European Journal Of Human Genetics : Ejhg
Versmissen, Jorie J; Oosterveer, Daniëlla M DM; Yazdanpanah, Mojgan M; Dehghan, Abbas A; Hólm, Hilma H; Erdman, Jeanette J; Aulchenko, Yurii S YS; Thorleifsson, Gudmar G; Schunkert, Heribert H; Huijgen, Roeland R; Vongpromek, Ranitha R; Uitterlinden, André G AG; Defesche, Joep C JC; van Duijn, Cornelia M CM; Mulder, Monique M; Dadd, Tony T; Karlsson, Hróbjartur D HD; Ordovas, Jose J; Kindt, Iris I; Jarman, Amelia A; Hofman, Albert A; van Vark-van der Zee, Leonie L; Blommesteijn-Touw, Adriana C AC; Kwekkeboom, Jaap J; Liem, Anho H AH; van der Ouderaa, Frans J FJ; Calandra, Sebastiano S; Bertolini, Stefano S; Averna, Maurizio M; Langslet, Gisle G; Ose, Leiv L; Ros, Emilio E; Almagro, Fátima F; de Leeuw, Peter W PW; Civeira, Fernando F; Masana, Luis L; Pintó, Xavier X; Simoons, Maarten L ML; Schinkel, Arend F L AF; Green, Martin R MR; Zwinderman, Aeilko H AH; Johnson, Keith J KJ; Schaefer, Arne A; Neil, Andrew A; Witteman, Jacqueline C M JC; Humphries, Steve E SE; Kastelein, John J P JJ; Sijbrands, Eric J G EJ
Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study.
Cardiovascular Diabetology
Adams, Jeremy N JN; Raffield, Laura M LM; Freedman, Barry I BI; Langefeld, Carl D CD; Ng, Maggie C Y MC; Carr, J Jeffrey JJ; Cox, Amanda J AJ; Bowden, Donald W DW
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.
Circulation
Go, Alan S AS; Mozaffarian, Dariush D; Roger, Véronique L VL; Benjamin, Emelia J EJ; Berry, Jarett D JD; Blaha, Michael J MJ; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Franco, Sheila S; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Huffman, Mark D MD; Judd, Suzanne E SE; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Mackey, Rachel H RH; Magid, David J DJ; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; McGuire, Darren K DK; Mohler, Emile R ER; Moy, Claudia S CS; Mussolino, Michael E ME; Neumar, Robert W RW; Nichol, Graham G; Pandey, Dilip K DK; Paynter, Nina P NP; Reeves, Matthew J MJ; Sorlie, Paul D PD; Stein, Joel J; Towfighi, Amytis A; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.
American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation
Olden, Matthias M; Teumer, Alexander A; Bochud, Murielle M; Pattaro, Cristian C; Köttgen, Anna A; Turner, Stephen T ST; Rettig, Rainer R; Chen, Ming-Huei MH; Dehghan, Abbas A; Bastardot, Francois F; Schmidt, Reinhold R; Vollenweider, Peter P; Schunkert, Heribert H; Reilly, Muredach P MP; Fornage, Myriam M; Launer, Lenore J LJ; Verwoert, Germaine C GC; Mitchell, Gary F GF; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Cheng, Ching-Yu CY; Sim, Xueling X; Siscovick, David S DS; Coresh, Josef J; Kao, W H Linda WH; Fox, Caroline S CS; O'Seaghdha, Conall M CM; ,
Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.
Bmc Medical Genetics
Pechlivanis, Sonali S; Mühleisen, Thomas W TW; Möhlenkamp, Stefan S; Schadendorf, Dirk D; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Hoffmann, Per P; Nöthen, Markus M MM; Scherag, André A; Moebus, Susanne S; ,
Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
Circulation
Go, Alan S AS; Mozaffarian, Dariush D; Roger, Véronique L VL; Benjamin, Emelia J EJ; Berry, Jarett D JD; Borden, William B WB; Bravata, Dawn M DM; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Franco, Sheila S; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Huffman, Mark D MD; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Magid, David D; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; McGuire, Darren K DK; Mohler, Emile R ER; Moy, Claudia S CS; Mussolino, Michael E ME; Nichol, Graham G; Paynter, Nina P NP; Schreiner, Pamela J PJ; Sorlie, Paul D PD; Stein, Joel J; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,
Large-scale association analysis identifies new risk loci for coronary artery disease.
Nature Genetics
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Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.
Plos One
Lucas, Gavin G; Lluís-Ganella, Carla C; Subirana, Isaac I; Musameh, Muntaser D MD; Gonzalez, Juan Ramon JR; Nelson, Christopher P CP; Sentí, Mariano M; , ; , ; Schwartz, Stephen M SM; Siscovick, David D; O'Donnell, Christopher J CJ; Melander, Olle O; Salomaa, Veikko V; Purcell, Shaun S; Altshuler, David D; Samani, Nilesh J NJ; Kathiresan, Sekar S; Elosua, Roberto R
Randomized trial of personal genomics for preventive cardiology: design and challenges.
Circulation. Cardiovascular Genetics
Knowles, Joshua W JW; Assimes, Themistocles L TL; Kiernan, Michaela M; Pavlovic, Aleksandra A; Goldstein, Benjamin A BA; Yank, Veronica V; McConnell, Michael V MV; Absher, Devin D; Bustamante, Carlos C; Ashley, Euan A EA; Ioannidis, John P A JP
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.
Plos One
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Heart disease and stroke statistics--2012 update: a report from the American Heart Association.
Circulation
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