Publications:

Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.

Scientific Reports

Aljarf, Raghad R; Shen, Mengyuan M; Pires, Douglas E V DEV; Ascher, David B DB

Publication Date: 2022-06-21

Variant appearance in text: BRCA2: L310S

PubMed Link: 35729312

Variant Present in the following documents:

• 41598_2022_13508_MOESM2_ESM.xlsx, sheet 1

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Prediction of the functional impact of missense variants in BRCA1 and BRCA2 with BRCA-ML.

Npj Breast Cancer

Hart, Steven N SN; Polley, Eric C EC; Shimelis, Hermella H; Yadav, Siddhartha S; Couch, Fergus J FJ

Publication Date: 2020

Variant appearance in text: BRCA2: 929T>C; Leu310Ser

PubMed Link: 32377563

Variant Present in the following documents:

• 41523_2020_159_MOESM3_ESM.xlsx, sheet 1

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Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Hart, Steven N SN; Hoskin, Tanya T; Shimelis, Hermela H; Moore, Raymond M RM; Feng, Bingjian B; Thomas, Abigail A; Lindor, Noralane M NM; Polley, Eric C EC; Goldgar, David E DE; Iversen, Edwin E; Monteiro, Alvaro N A ANA; Suman, Vera J VJ; Couch, Fergus J FJ

Publication Date: 2019-01

Variant appearance in text: BRCA2: L310S

PubMed Link: 29884841

Variant Present in the following documents:

• NIHMS953431-supplement-Table_S2.xls, sheet 1

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Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2.

The Embo Journal

Shin, David S DS; Pellegrini, Luca L; Daniels, Douglas S DS; Yelent, Biana B; Craig, Lisa L; Bates, Debbie D; Yu, David S DS; Shivji, Mahmud K MK; Hitomi, Chiharu C; Arvai, Andrew S AS; Volkmann, Niels N; Tsuruta, Hiro H; Blundell, Tom L TL; Venkitaraman, Ashok R AR; Tainer, John A JA

Publication Date: 2003-09-01

Variant appearance in text: BRCA2: L310S

PubMed Link: 12941707

Variant Present in the following documents:

• Main text

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