BRCA2 c.4434_4492delinsTT ;(p.S1479_G1498delinsC)

Variant ID: 13-32912926-AAGTTATGAGGAAACAGACATAGTTAAACACAAAATACTGAAAGAAAGTGTCCCAGTTG-TT

NM_000059.3(BRCA2):c.4434_4492delinsTT;(p.S1479_G1498delinsC)

This variant was identified in 3 publications

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

Role of PARP in TNBC: Mechanism of Inhibition, Clinical Applications, and Resistance.

Biomedicines
Singh, Desh Deepak DD; Parveen, Amna A; Yadav, Dharmendra Kumar DK
Publication Date: 2021-10-21

Variant appearance in text: BRCA2: 4434_5686delinsTT
PubMed Link: 34829741
Variant Present in the following documents:
  • Main text
  • biomedicines-09-01512.pdf
View BVdb publication page


PARP inhibitor resistance: the underlying mechanisms and clinical implications.

Molecular Cancer
Li, He H; Liu, Zhao-Yi ZY; Wu, Nayiyuan N; Chen, Yong-Chang YC; Cheng, Quan Q; Wang, Jing J
Publication Date: 2020-06-20

Variant appearance in text: BRCA2: 4434_5686delinsTT
PubMed Link: 32563252
Variant Present in the following documents:
  • Main text
  • 12943_2020_Article_1227.pdf
View BVdb publication page


Acquired multiple secondary BRCA2 mutations upon PARPi resistance in a metastatic pancreatic cancer patient harboring a BRCA2 germline mutation.

American Journal Of Translational Research
Tao, Haitao H; Liu, Sisi S; Huang, Di D; Han, Xiao X; Wu, Xue X; Shao, Yang W YW; Hu, Yi Y
Publication Date: 2020

Variant appearance in text: BRCA2: 4434_5686delinsTT
PubMed Link: 32194909
Variant Present in the following documents:
  • Main text
View BVdb publication page