Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
Cancer Research
Yoon, Sang Jun SJ; Combs, Joseph A JA; Falzone, Aimee A; Prieto-Farigua, Nicolas N; Caldwell, Samantha S; Ackerman, Hayley D HD; Flores, Elsa R ER; DeNicola, Gina M GM
Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.
Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes.
Nature Communications
Bebber, Christina M CM; Thomas, Emily S ES; Stroh, Jenny J; Chen, Zhiyi Z; Androulidaki, Ariadne A; Schmitt, Anna A; Höhne, Michaela N MN; Stüker, Lukas L; de Pádua Alves, Cleidson C; Khonsari, Armin A; Dammert, Marcel A MA; Parmaksiz, Fatma F; Tumbrink, Hannah L HL; Beleggia, Filippo F; Sos, Martin L ML; Riemer, Jan J; George, Julie J; Brodesser, Susanne S; Thomas, Roman K RK; Reinhardt, H Christian HC; von Karstedt, Silvia S
The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.
The Journal Of Cell Biology
Nowak, Dawid G DG; Katsenelson, Ksenya Cohen KC; Watrud, Kaitlin E KE; Chen, Muhan M; Mathew, Grinu G; D'Andrea, Vincent D VD; Lee, Matthew F MF; Swamynathan, Manojit Mosur MM; Casanova-Salas, Irene I; Jibilian, Megan C MC; Buckholtz, Caroline L CL; Ambrico, Alexandra J AJ; Pan, Chun-Hao CH; Wilkinson, John E JE; Newton, Alexandra C AC; Trotman, Lloyd C LC
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.
Nature Reviews. Cancer
Rudin, Charles M CM; Poirier, John T JT; Byers, Lauren Averett LA; Dive, Caroline C; Dowlati, Afshin A; George, Julie J; Heymach, John V JV; Johnson, Jane E JE; Lehman, Jonathan M JM; MacPherson, David D; Massion, Pierre P PP; Minna, John D JD; Oliver, Trudy G TG; Quaranta, Vito V; Sage, Julien J; Thomas, Roman K RK; Vakoc, Christopher R CR; Gazdar, Adi F AF
A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.
Breast Cancer Research And Treatment
Hollern, Daniel P DP; Contreras, Cristina M CM; Dance-Barnes, Stephanie S; Silva, Grace O GO; Pfefferle, Adam D AD; Xiong, Jessie J; Darr, David B DB; Usary, Jerry J; Mott, Kevin R KR; Perou, Charles M CM
MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.
Cancer Cell
Mollaoglu, Gurkan G; Guthrie, Matthew R MR; Böhm, Stefanie S; Brägelmann, Johannes J; Can, Ismail I; Ballieu, Paul M PM; Marx, Annika A; George, Julie J; Heinen, Christine C; Chalishazar, Milind D MD; Cheng, Haixia H; Ireland, Abbie S AS; Denning, Kendall E KE; Mukhopadhyay, Anandaroop A; Vahrenkamp, Jeffery M JM; Berrett, Kristofer C KC; Mosbruger, Timothy L TL; Wang, Jun J; Kohan, Jessica L JL; Salama, Mohamed E ME; Witt, Benjamin L BL; Peifer, Martin M; Thomas, Roman K RK; Gertz, Jason J; Johnson, Jane E JE; Gazdar, Adi F AF; Wechsler-Reya, Robert J RJ; Sos, Martin L ML; Oliver, Trudy G TG
Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Brown, Jennifer R JR; Hanna, Megan M; Tesar, Bethany B; Werner, Lillian L; Pochet, Nathalie N; Asara, John M JM; Wang, Yaoyu E YE; Dal Cin, Paola P; Fernandes, Stacey M SM; Thompson, Christina C; Macconaill, Laura L; Wu, Catherine J CJ; Van de Peer, Yves Y; Correll, Mick M; Regev, Aviv A; Neuberg, Donna D; Freedman, Arnold S AS