RB1 c.172A>G ;(p.T58A)

Variant ID: 13-48881450-A-G

NM_000321.2(RB1):c.172A>G;(p.T58A)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.

Cancer Research
Yoon, Sang Jun SJ; Combs, Joseph A JA; Falzone, Aimee A; Prieto-Farigua, Nicolas N; Caldwell, Samantha S; Ackerman, Hayley D HD; Flores, Elsa R ER; DeNicola, Gina M GM
Publication Date: 2023-03-02

Variant appearance in text: RB1: T58A
PubMed Link: 36862034
Variant Present in the following documents:
  • Main text
  • 1426.pdf
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MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.

Molecular Cancer
Khan, Parvez P; Siddiqui, Jawed Akhtar JA; Kshirsagar, Prakash G PG; Venkata, Ramakanth Chirravuri RC; Maurya, Shailendra Kumar SK; Mirzapoiazova, Tamara T; Perumal, Naveenkumar N; Chaudhary, Sanjib S; Kanchan, Ranjana Kumari RK; Fatima, Mahek M; Khan, Md Arafat MA; Rehman, Asad Ur AU; Lakshmanan, Imayavaramban I; Mahapatra, Sidharth S; Talmon, Geoffrey A GA; Kulkarni, Prakash P; Ganti, Apar K AK; Jain, Maneesh M; Salgia, Ravi R; Batra, Surinder Kumar SK; Nasser, Mohd Wasim MW
Publication Date: 2023-01-04

Variant appearance in text: RB1: T58A
PubMed Link: 36597126
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Publication Date: 2022

Variant appearance in text: RB1: 172A>G; T58A
PubMed Link: 35814426
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



Killing SCLC: insights into how to target a shapeshifting tumor.

Genes & Development
Sutherland, Kate D KD; Ireland, Abbie S AS; Oliver, Trudy G TG
Publication Date: 2022-03-01

Variant appearance in text: RB1: T58A
PubMed Link: 35318269
Variant Present in the following documents:
  • Main text
  • 241.pdf
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Oh, the Mutations You'll Acquire! A Systematic Overview of Cutaneous Squamous Cell Carcinoma.

Cellular Physiology And Biochemistry : International Journal Of Experimental Cellular Physiology, Biochemistry, And Pharmacology
Droll, Stephenie S; Bao, Xiaomin X
Publication Date: 2021-09-22

Variant appearance in text: RB1: T58A
PubMed Link: 34553848
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes.

Nature Communications
Bebber, Christina M CM; Thomas, Emily S ES; Stroh, Jenny J; Chen, Zhiyi Z; Androulidaki, Ariadne A; Schmitt, Anna A; Höhne, Michaela N MN; Stüker, Lukas L; de Pádua Alves, Cleidson C; Khonsari, Armin A; Dammert, Marcel A MA; Parmaksiz, Fatma F; Tumbrink, Hannah L HL; Beleggia, Filippo F; Sos, Martin L ML; Riemer, Jan J; George, Julie J; Brodesser, Susanne S; Thomas, Roman K RK; Reinhardt, H Christian HC; von Karstedt, Silvia S
Publication Date: 2021-04-06

Variant appearance in text: RB1: T58A
PubMed Link: 33824345
Variant Present in the following documents:
  • Main text
View BVdb publication page



Neuroendocrine Lung Cancer Mouse Models: An Overview.

Cancers
Lorz, Corina C; Oteo, Marta M; Santos, Mirentxu M
Publication Date: 2020-12-22

Variant appearance in text: RB1: T58A
PubMed Link: 33375066
Variant Present in the following documents:
  • Main text
  • cancers-13-00014.pdf
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The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.

The Journal Of Cell Biology
Nowak, Dawid G DG; Katsenelson, Ksenya Cohen KC; Watrud, Kaitlin E KE; Chen, Muhan M; Mathew, Grinu G; D'Andrea, Vincent D VD; Lee, Matthew F MF; Swamynathan, Manojit Mosur MM; Casanova-Salas, Irene I; Jibilian, Megan C MC; Buckholtz, Caroline L CL; Ambrico, Alexandra J AJ; Pan, Chun-Hao CH; Wilkinson, John E JE; Newton, Alexandra C AC; Trotman, Lloyd C LC
Publication Date: 2019-06-03

Variant appearance in text: RB1: T58A
PubMed Link: 31092557
Variant Present in the following documents:
  • Main text
  • JCB_201902048.pdf
View BVdb publication page



Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.

Nature Reviews. Cancer
Rudin, Charles M CM; Poirier, John T JT; Byers, Lauren Averett LA; Dive, Caroline C; Dowlati, Afshin A; George, Julie J; Heymach, John V JV; Johnson, Jane E JE; Lehman, Jonathan M JM; MacPherson, David D; Massion, Pierre P PP; Minna, John D JD; Oliver, Trudy G TG; Quaranta, Vito V; Sage, Julien J; Thomas, Roman K RK; Vakoc, Christopher R CR; Gazdar, Adi F AF
Publication Date: 2019-05

Variant appearance in text: RB1: T58A
PubMed Link: 30926931
Variant Present in the following documents:
  • Main text
View BVdb publication page



A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.

Breast Cancer Research And Treatment
Hollern, Daniel P DP; Contreras, Cristina M CM; Dance-Barnes, Stephanie S; Silva, Grace O GO; Pfefferle, Adam D AD; Xiong, Jessie J; Darr, David B DB; Usary, Jerry J; Mott, Kevin R KR; Perou, Charles M CM
Publication Date: 2019-02

Variant appearance in text: RB1: T58A
PubMed Link: 30484104
Variant Present in the following documents:
  • 10549_2018_Article_5061.pdf
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Autochthonous murine models for the study of smoker and never-smoker associated lung cancers.

Translational Lung Cancer Research
Akbay, Esra A EA; Kim, James J
Publication Date: 2018-08

Variant appearance in text: RB1: T58A
PubMed Link: 30225211
Variant Present in the following documents:
  • Main text
View BVdb publication page



Unravelling the biology of SCLC: implications for therapy.

Nature Reviews. Clinical Oncology
Sabari, Joshua K JK; Lok, Benjamin H BH; Laird, James H JH; Poirier, John T JT; Rudin, Charles M CM
Publication Date: 2017-09

Variant appearance in text: RB1: T58A
PubMed Link: 28534531
Variant Present in the following documents:
  • Main text
View BVdb publication page



MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.

Cancer Cell
Mollaoglu, Gurkan G; Guthrie, Matthew R MR; Böhm, Stefanie S; Brägelmann, Johannes J; Can, Ismail I; Ballieu, Paul M PM; Marx, Annika A; George, Julie J; Heinen, Christine C; Chalishazar, Milind D MD; Cheng, Haixia H; Ireland, Abbie S AS; Denning, Kendall E KE; Mukhopadhyay, Anandaroop A; Vahrenkamp, Jeffery M JM; Berrett, Kristofer C KC; Mosbruger, Timothy L TL; Wang, Jun J; Kohan, Jessica L JL; Salama, Mohamed E ME; Witt, Benjamin L BL; Peifer, Martin M; Thomas, Roman K RK; Gertz, Jason J; Johnson, Jane E JE; Gazdar, Adi F AF; Wechsler-Reya, Robert J RJ; Sos, Martin L ML; Oliver, Trudy G TG
Publication Date: 2017-02-13

Variant appearance in text: RB1: T58A
PubMed Link: 28089889
Variant Present in the following documents:
  • Main text
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Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Brown, Jennifer R JR; Hanna, Megan M; Tesar, Bethany B; Werner, Lillian L; Pochet, Nathalie N; Asara, John M JM; Wang, Yaoyu E YE; Dal Cin, Paola P; Fernandes, Stacey M SM; Thompson, Christina C; Macconaill, Laura L; Wu, Catherine J CJ; Van de Peer, Yves Y; Correll, Mick M; Regev, Aviv A; Neuberg, Donna D; Freedman, Arnold S AS
Publication Date: 2012-07-15

Variant appearance in text: RB1: Thr58Ala
PubMed Link: 22623730
Variant Present in the following documents:
  • Main text
View BVdb publication page