PSEN1 c.151T>G ;(p.S51A)

Variant ID: 14-73637568-T-G

NM_000021.3(PSEN1):c.151T>G;(p.S51A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease.

Open Biology
Hashimoto, Shoko S; Saido, Takaomi C TC
Publication Date: 2018-04

Variant appearance in text: PS1: S51A
PubMed Link: 29695619
Variant Present in the following documents:
  • Main text
  • rsob-8-180024.pdf
View BVdb publication page



Restoring synaptic plasticity and memory in mouse models of Alzheimer's disease by PKR inhibition.

Molecular Brain
Hwang, Kyoung-Doo KD; Bak, Myeong Seong MS; Kim, Sang Jeong SJ; Rhee, Sangmyung S; Lee, Yong-Seok YS
Publication Date: 2017-12-13

Variant appearance in text: PS1: S51A
PubMed Link: 29233183
Variant Present in the following documents:
  • Main text
  • 13041_2017_Article_338.pdf
View BVdb publication page



Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer's Disease.

Neural Plasticity
Papazoglou, Anna A; Soos, Julien J; Lundt, Andreas A; Wormuth, Carola C; Ginde, Varun Raj VR; Müller, Ralf R; Henseler, Christina C; Broich, Karl K; Xie, Kan K; Ehninger, Dan D; Haenisch, Britta B; Weiergräber, Marco M
Publication Date: 2016

Variant appearance in text: PS1: S51A
PubMed Link: 27840743
Variant Present in the following documents:
  • Main text
View BVdb publication page



Limited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer's disease.

Neural Plasticity
Paesler, Katharina K; Xie, Kan K; Hettich, Moritz M MM; Siwek, Magdalena E ME; Ryan, Devon P DP; Schröder, Susanne S; Papazoglou, Anna A; Broich, Karl K; Müller, Ralf R; Trog, Astrid A; Garthe, Alexander A; Kempermann, Gerd G; Weiergräber, Marco M; Ehninger, Dan D
Publication Date: 2015

Variant appearance in text: PSEN1: S51A
PubMed Link: 25883808
Variant Present in the following documents:
  • Main text
  • NP2015-825157.pdf
View BVdb publication page



Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.

Plos One
Sadleir, Katherine R KR; Eimer, William A WA; Kaufman, Randal J RJ; Osten, Pavel P; Vassar, Robert R
Publication Date: 2014

Variant appearance in text: PS1: S51A
PubMed Link: 24992504
Variant Present in the following documents:
  • Main text
View BVdb publication page



Roles of eIF2α kinases in the pathogenesis of Alzheimer's disease.

Frontiers In Molecular Neuroscience
Ohno, Masuo M
Publication Date: 2014

Variant appearance in text: PS1: S51A
PubMed Link: 24795560
Variant Present in the following documents:
  • Main text
  • fnmol-07-00022.pdf
View BVdb publication page