Publications:

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Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy.

Journal Of Ginseng Research

Wang, Ni N; Yang, Junyan J; Chen, Ruijun R; Liu, Yunyun Y; Liu, Shunjie S; Pan, Yining Y; Lei, Qingfeng Q; Wang, Yuzhou Y; He, Lu L; Song, Youqiang Y; Li, Zhong Z

Publication Date: 2023-05

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PubMed Link: 37252274

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"Dirty Dancing" of Calcium and Autophagy in Alzheimer's Disease.

Life (Basel, Switzerland)

Zhang, Hua H; Bezprozvanny, Ilya I

Publication Date: 2023-05-15

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PubMed Link: 37240832

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• life-13-01187.pdf

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Complexity of Sex Differences and Their Impact on Alzheimer's Disease.

Biomedicines

Kadlecova, Marion M; Freude, Kristine K; Haukedal, Henriette H

Publication Date: 2023-04-24

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PubMed Link: 37238932

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• biomedicines-11-01261.pdf

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Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology.

Acta Neuropathologica Communications

Suelves, Nuria N; Saleki, Shirine S; Ibrahim, Tasha T; Palomares, Debora D; Moonen, Sebastiaan S; Koper, Marta J MJ; Vrancx, Céline C; Vadukul, Devkee M DM; Papadopoulos, Nicolas N; Viceconte, Nikenza N; Claude, Eloïse E; Vandenberghe, Rik R; von Arnim, Christine A F CAF; Constantinescu, Stefan N SN; Thal, Dietmar Rudolf DR; Decottignies, Anabelle A; Kienlen-Campard, Pascal P

Publication Date: 2023-05-17

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PubMed Link: 37198698

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• 40478_2023_Article_1578.pdf

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Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column: Analysis of the Hippocampus from the 5xFAD Alzheimer's Disease Mouse Model.

Cells

Thanou, Evangelia E; Koopmans, Frank F; Pita-Illobre, Débora D; Klaassen, Remco V RV; Özer, Berna B; Charalampopoulos, Ioannis I; Smit, August B AB; Li, Ka Wan KW

Publication Date: 2023-04-25

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PubMed Link: 37174641

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• cells-12-01242.pdf

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GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression.

Frontiers In Molecular Neuroscience

Lee, Ye Ji YJ; Jeong, Ye Ji YJ; Kang, Eun Ji EJ; Kang, Beom Seok BS; Lee, Song Hee SH; Kim, You Jin YJ; Kang, Seong Su SS; Suh, Sang Won SW; Ahn, Eun Hee EH

Publication Date: 2023

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PubMed Link: 37143467

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• fnmol-16-1150399.pdf

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Gamma sensory entrainment for cognitive improvement in neurodegenerative diseases: opportunities and challenges ahead.

Frontiers In Integrative Neuroscience

Sahu, Prangya Parimita PP; Tseng, Philip P

Publication Date: 2023

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PubMed Link: 37138796

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• fnint-17-1146687.pdf

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A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates.

Plos One

Anwer, Danish M DM; Gubinelli, Francesco F; Kurt, Yunus A YA; Sarauskyte, Livija L; Jacobs, Febe F; Venuti, Chiara C; Sandoval, Ivette M IM; Yang, Yiyi Y; Stancati, Jennifer J; Mazzocchi, Martina M; Brandi, Edoardo E; O'Keeffe, Gerard G; Steece-Collier, Kathy K; Li, Jia-Yi JY; Deierborg, Tomas T; Manfredsson, Fredric P FP; Davidsson, Marcus M; Heuer, Andreas A

Publication Date: 2023

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PubMed Link: 37126506

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• pone.0284480.pdf

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What can traditional Chinese medicine do for adult neurogenesis?

Frontiers In Neuroscience

Shen, Wei W; Jiang, Ning N; Zhou, Wenxia W

Publication Date: 2023

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PubMed Link: 37123359

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• fnins-17-1158228.pdf

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Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice.

Life (Basel, Switzerland)

Bader, Angelika Sabine AS; Gnädig, Marius-Uwe MU; Fricke, Merle M; Büschgens, Luca L; Berger, Lena Josefine LJ; Klafki, Hans-Wolfgang HW; Meyer, Thomas T; Jahn, Olaf O; Weggen, Sascha S; Wirths, Oliver O

Publication Date: 2023-04-20

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PubMed Link: 37109582

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• life-13-01053.pdf

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Alzheimer's disease-specific cytokine secretion suppresses neuronal mitochondrial metabolism.

Biorxiv : The Preprint Server For Biology

Kuhn, Madison K MK; Fleeman, Rebecca M RM; Beidler, Lynne M LM; Snyder, Amanda M AM; Chan, Dennis C DC; Proctor, Elizabeth A EA

Publication Date: 2023-04-07

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PubMed Link: 37066287

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• Main text
• nihpp-2023.04.07.536014v1.pdf

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Long-Term Administration of Vespa velutina nigrithorax Venom Ameliorates Alzheimer's Phenotypes in 5xFAD Transgenic Mice.

Toxins

Jeong, Yoon Ah YA; Yun, Hyun Seok HS; Kim, Yoonsu Y; Jang, Chan Ho CH; Lim, Ji Sun JS; Kim, Hyo Jung HJ; Choi, Moon Bo MB; Jung, Jae Woo JW; Oh, Jisun J; Kim, Jong-Sang JS

Publication Date: 2023-03-06

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PubMed Link: 36977094

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• Main text
• toxins-15-00203.pdf

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Neutrophils as a potential therapeutic target in Alzheimer's disease.

Frontiers In Immunology

Aries, Michelle L ML; Hensley-McBain, Tiffany T

Publication Date: 2023

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PubMed Link: 36936930

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• Main text
• fimmu-14-1123149.pdf

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EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Yang, Hyunjun H; Yuan, Peng P; Wu, Yibing Y; Shi, Marie M; Caro, Christoffer D CD; Tengeiji, Atsushi A; Yamanoi, Shigeo S; Inoue, Masahiro M; DeGrado, William F WF; Condello, Carlo C

Publication Date: 2023-03-21

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PubMed Link: 36927157

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• pnas.2300769120.sapp.pdf

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Attenuation of Alzheimer's brain pathology in 5XFAD mice by PTH1-34, a peptide of parathyroid hormone.

Alzheimer'S Research & Therapy

Chen, Li L; Xiong, Lei L; Yao, Lingling L; Pan, Jinxiu J; Arzola, Emily E; Zhu, Xiaojuan X; Mei, Lin L; Xiong, Wen-Cheng WC

Publication Date: 2023-03-14

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PubMed Link: 36918976

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• Main text
• 13195_2023_Article_1202.pdf

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Sex Differences between Neuronal Loss and the Early Onset of Amyloid Deposits and Behavioral Consequences in 5xFAD Transgenic Mouse as a Model for Alzheimer's Disease.

Cells

Poon, Chi Him CH; Wong, San Tung Nicholas STN; Roy, Jaydeep J; Wang, Yingyi Y; Chan, Hui Wang Hujo HWH; Steinbusch, Harry H; Blokland, Arjan A; Temel, Yasin Y; Aquili, Luca L; Lim, Lee Wei LW

Publication Date: 2023-03-01

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PubMed Link: 36899916

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• Main text
• cells-12-00780.pdf

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Integrated multi-omics analysis of Alzheimer's disease shows molecular signatures associated with disease progression and potential therapeutic targets.

Scientific Reports

Kodam, Pradeep P; Sai Swaroop, R R; Pradhan, Sai Sanwid SS; Sivaramakrishnan, Venketesh V; Vadrevu, Ramakrishna R

Publication Date: 2023-03-06

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PubMed Link: 36879094

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• 41598_2023_30892_MOESM12_ESM.pdf

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From attention-deficit hyperactivity disorder to sporadic Alzheimer's disease-Wnt/mTOR pathways hypothesis.

Frontiers In Neuroscience

Grünblatt, Edna E; Homolak, Jan J; Babic Perhoc, Ana A; Davor, Virag V; Knezovic, Ana A; Osmanovic Barilar, Jelena J; Riederer, Peter P; Walitza, Susanne S; Tackenberg, Christian C; Salkovic-Petrisic, Melita M

Publication Date: 2023

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PubMed Link: 36875654

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• fnins-17-1104985.pdf

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CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.

Science Advances

Gouveia Roque, Cláudio C; Chung, Kyung Min KM; McCurdy, Ethan P EP; Jagannathan, Radhika R; Randolph, Lisa K LK; Herline-Killian, Krystal K; Baleriola, Jimena J; Hengst, Ulrich U

Publication Date: 2023-03-03

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PubMed Link: 36867706

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• sciadv.add2671.pdf

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: PSEN1: 436A>C; Met146Leu

PubMed Link: 36823319

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• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

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Investigational treatments for neurodegenerative diseases caused by inheritance of gene mutations: lessons from recent clinical trials.

Neural Regeneration Research

Imbimbo, Bruno P BP; Triaca, Viviana V; Imbimbo, Camillo C; Nisticò, Robert R

Publication Date: 2023-08

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PubMed Link: 36751779

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• NRR-18-1679.pdf

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Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42 in Alzheimer's disease.

Scientific Reports

Fertan, Emre E; Gendron, William H WH; Wong, Aimée A AA; Hanson, Gabrielle M GM; Brown, Richard E RE; Weaver, Ian C G ICG

Publication Date: 2023-02-04

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PubMed Link: 36739453

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• 41598_2023_Article_29248.pdf

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TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer's disease via TFEB/TFE3 activation.

Journal Of Neuroinflammation

Lin, Wenjia W; Li, Zhao Z; Liang, Guangfeng G; Zhou, Runjin R; Zheng, Xiaoyan X; Tao, Rongrong R; Huo, Qingwei Q; Su, Chengfu C; Li, Min M; Xu, Nenggui N; Tang, Chunzhi C; Song, Ju-Xian JX

Publication Date: 2023-02-02

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PubMed Link: 36732771

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• 12974_2023_Article_2698.pdf

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Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.

Molecular Neurodegeneration

Kisler, Kassandra K; Sagare, Abhay P AP; Lazic, Divna D; Bazzi, Sam S; Lawson, Erica E; Hsu, Ching-Ju CJ; Wang, Yaoming Y; Ramanathan, Anita A; Nelson, Amy R AR; Zhao, Zhen Z; Zlokovic, Berislav V BV

Publication Date: 2023-01-27

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PubMed Link: 36707892

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• 13024_2023_Article_597.pdf

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Leveraging genetic diversity in mice to inform individual differences in brain microstructure and memory.

Frontiers In Behavioral Neuroscience

Murdy, Thomas J TJ; Dunn, Amy R AR; Singh, Surjeet S; Telpoukhovskaia, Maria A MA; Zhang, Shanrong S; White, Jacqueline K JK; Kahn, Itamar I; Febo, Marcelo M; Kaczorowski, Catherine C CC

Publication Date: 2022

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PubMed Link: 36703722

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• fnbeh-16-1033975.pdf

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Deletion of the Alzheimer's disease risk gene Abi3 locus results in obesity and systemic metabolic disruption in mice.

Frontiers In Aging Neuroscience

Smith, Daniel C DC; Karahan, Hande H; Wijeratne, H R Sagara HRS; Al-Amin, Mamun M; McCord, Brianne B; Moon, Younghye Y; Kim, Jungsu J

Publication Date: 2022

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PubMed Link: 36620768

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• fnagi-14-1035572.pdf

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Knee osteoarthritis accelerates amyloid beta deposition and neurodegeneration in a mouse model of Alzheimer's disease.

Molecular Brain

Gupta, Deepak Prasad DP; Lee, Young-Sun YS; Choe, Youngshik Y; Kim, Kun-Tae KT; Song, Gyun Jee GJ; Hwang, Sun-Chul SC

Publication Date: 2023-01-02

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PubMed Link: 36593507

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• 13041_2022_Article_986.pdf

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Novel Algorithm of Network Calcium Dynamics Analysis for Studying the Role of Astrocytes in Neuronal Activity in Alzheimer's Disease Models.

International Journal Of Molecular Sciences

Mitroshina, Elena V EV; Pakhomov, Alexander M AM; Krivonosov, Mikhail I MI; Yarkov, Roman S RS; Gavrish, Maria S MS; Shkirin, Alexey V AV; Ivanchenko, Mikhail V MV; Vedunova, Maria V MV

Publication Date: 2022-12-14

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PubMed Link: 36555569

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• ijms-23-15928.pdf

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Glial Gap Junction Pathology in the Spinal Cord of the 5xFAD Mouse Model of Early-Onset Alzheimer's Disease.

International Journal Of Molecular Sciences

Pechlivanidou, Maria M; Kousiappa, Ioanna I; Angeli, Stella S; Sargiannidou, Irene I; Koupparis, Andreas M AM; Papacostas, Savvas S SS; Kleopa, Kleopas A KA

Publication Date: 2022-12-09

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PubMed Link: 36555237

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• ijms-23-15597.pdf

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Mitochondrial dysfunction of induced pluripotent stem cells-based neurodegenerative disease modeling and therapeutic strategy.

Frontiers In Cell And Developmental Biology

Luo, Hong-Mei HM; Xu, Jia J; Huang, Dan-Xia DX; Chen, Yun-Qiang YQ; Liu, Yi-Zhou YZ; Li, Ya-Jie YJ; Chen, Hong H

Publication Date: 2022

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PubMed Link: 36478742

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• Main text
• fcell-10-1030390.pdf

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Comprehensive analysis of dysregulated circular RNAs and construction of a ceRNA network involved in the pathology of Alzheimer's disease in a 5 × FAD mouse model.

Frontiers In Aging Neuroscience

Sun, Ting T; Zeng, Li L; Cai, Zhongdi Z; Liu, Qingshan Q; Li, Zhuorong Z; Liu, Rui R

Publication Date: 2022

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PubMed Link: 36466608

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• Main text
• fnagi-14-1020699.pdf

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Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models.

Alzheimer'S Research & Therapy

Lee, Hee Yang HY; Yoon, Soljee S; Lee, Jeong Hwa JH; Park, Keunwan K; Jung, Youngeun Y; Cho, Illhwan I; Lee, Donghee D; Shin, Jisu J; Kim, Kyeonghwan K; Kim, Sunmi S; Kim, Jimin J; Kim, Koeun K; Han, Seung Hoon SH; Kim, Seong Muk SM; Kim, Hye Ju HJ; Kim, Hye Yun HY; Kim, Ikyon I; Kim, Young Soo YS

Publication Date: 2022-11-29

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PubMed Link: 36443837

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• Main text
• 13195_2022_Article_1112.pdf

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Alzheimer's Disease: Treatment Strategies and Their Limitations.

International Journal Of Molecular Sciences

Passeri, Elodie E; Elkhoury, Kamil K; Morsink, Margaretha M; Broersen, Kerensa K; Linder, Michel M; Tamayol, Ali A; Malaplate, Catherine C; Yen, Frances T FT; Arab-Tehrany, Elmira E

Publication Date: 2022-11-12

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PubMed Link: 36430432

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• ijms-23-13954.pdf

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MicroRNA super-resolution imaging in blood for Alzheimer's disease.

Bmb Reports

Lee, Mirae M; Woo, Jiwon J; Kim, Sang Tae ST; Moon, Minho M; Kim, Sang Yun SY; Cho, Hanna H; Kim, Sujin S; Kim, Han-Kyeol HK; Park, Jeong-Yoon JY

Publication Date: 2022-11-21

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PubMed Link: 36404596

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• bmb-56-3-190-supple.pdf

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Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer's Disease.

Molecular Neurobiology

Puris, Elena E; Saveleva, Liudmila L; de Sousa Maciel, Izaque I; Kanninen, Katja M KM; Auriola, Seppo S; Fricker, Gert G

Publication Date: 2022-11-11

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PubMed Link: 36367657

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• 12035_2022_Article_3111.pdf

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The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer's Disease.

Cells

Busch, Lukas L; Eggert, Simone S; Endres, Kristina K; Bufe, Bernd B

Publication Date: 2022-10-29

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PubMed Link: 36359817

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• cells-11-03421.pdf

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Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer's Disease.

Biomedicines

Ameen, Aishat O AO; Freude, Kristine K; Aldana, Blanca I BI

Publication Date: 2022-11-01

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PubMed Link: 36359298

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• biomedicines-10-02778.pdf

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