Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology.
Embo Reports
Radde, Rebecca R; Bolmont, Tristan T; Kaeser, Stephan A SA; Coomaraswamy, Janaky J; Lindau, Dennis D; Stoltze, Lars L; Calhoun, Michael E ME; Jäggi, Fabienne F; Wolburg, Hartwig H; Gengler, Simon S; Haass, Christian C; Ghetti, Bernardino B; Czech, Christian C; Hölscher, Christian C; Mathews, Paul M PM; Jucker, Mathias M
Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Moehlmann, Tobias T; Winkler, Edith E; Xia, Xuefeng X; Edbauer, Dieter D; Murrell, Jill J; Capell, Anja A; Kaether, Christoph C; Zheng, Hui H; Ghetti, Bernardino B; Haass, Christian C; Steiner, Harald H