Publications:

Patient-derived xenografts and organoids model therapy response in prostate cancer.

Nature Communications

Karkampouna, Sofia S; La Manna, Federico F; Benjak, Andrej A; Kiener, Mirjam M; De Menna, Marta M; Zoni, Eugenio E; Grosjean, Joël J; Klima, Irena I; Garofoli, Andrea A; Bolis, Marco M; Vallerga, Arianna A; Theurillat, Jean-Philippe JP; De Filippo, Maria R MR; Genitsch, Vera V; Keller, David D; Booij, Tijmen H TH; Stirnimann, Christian U CU; Eng, Kenneth K; Sboner, Andrea A; Ng, Charlotte K Y CKY; Piscuoglio, Salvatore S; Gray, Peter C PC; Spahn, Martin M; Rubin, Mark A MA; Thalmann, George N GN; Kruithof-de Julio, Marianna M

Publication Date: 2021-02-18

Variant appearance in text: PSEN1: Leu241Ile

PubMed Link: 33602919

Variant Present in the following documents:

• 41467_2021_21300_MOESM5_ESM.xlsx, sheet 3

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Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides.

The Journal Of Biological Chemistry

Liu, Lei L; Lauro, Bianca M BM; Wolfe, Michael S MS; Selkoe, Dennis J DJ

Publication Date: 2021

Variant appearance in text: PS1: L241I

PubMed Link: 33571524

Variant Present in the following documents:

• Main text
• main.pdf

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Nicastrin is dispensable for gamma-secretase protease activity in the presence of specific presenilin mutations.

The Journal Of Biological Chemistry

Futai, Eugene E; Yagishita, Sosuke S; Ishiura, Shoichi S

Publication Date: 2009-05-08

Variant appearance in text: PS1: L241I

PubMed Link: 19254953

Variant Present in the following documents:

• 13013.pdf

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