Publications:

Phenylpiperidine-type γ-secretase modulators target the transmembrane domain 1 of presenilin 1.

The Embo Journal

Ohki, Yu Y; Higo, Takuya T; Uemura, Kengo K; Shimada, Naoaki N; Osawa, Satoko S; Berezovska, Oksana O; Yokoshima, Satoshi S; Fukuyama, Tohru T; Tomita, Taisuke T; Iwatsubo, Takeshi T

Publication Date: 2011-10-14

Variant appearance in text: PS1: A246C

PubMed Link: 22002539

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Participation of transmembrane domain 1 of presenilin 1 in the catalytic pore structure of the γ-secretase.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Takagi, Shizuka S; Tominaga, Aya A; Sato, Chihiro C; Tomita, Taisuke T; Iwatsubo, Takeshi T

Publication Date: 2010-11-24

Variant appearance in text: PS1: A246C

PubMed Link: 21106832

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Structure of the catalytic pore of gamma-secretase probed by the accessibility of substituted cysteines.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Sato, Chihiro C; Morohashi, Yuichi Y; Tomita, Taisuke T; Iwatsubo, Takeshi T

Publication Date: 2006-11-15

Variant appearance in text: PS1: A246C

PubMed Link: 17108181

Variant Present in the following documents:

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