Publications:

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Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development.

Plos One

Ledo, Jose Henrique JH; Zhang, Ran R; Mesin, Luka L; Mourão-Sá, Diego D; Azevedo, Estefania P EP; Troyanskaya, Olga G OG; Bustos, Victor V; Greengard, Paul P

Publication Date: 2020

Variant appearance in text: PS1: S367A

PubMed Link: 32822378

Variant Present in the following documents:

• Main text

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Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia.

Molecular Psychiatry

Ledo, Jose Henrique JH; Liebmann, Thomas T; Zhang, Ran R; Chang, Jerry C JC; Azevedo, Estefania P EP; Wong, Eitan E; Silva, Hernandez Moura HM; Troyanskaya, Olga G OG; Bustos, Victor V; Greengard, Paul P

Publication Date: 2021-10

Variant appearance in text: PS1: S367A

PubMed Link: 32792660

Variant Present in the following documents:

• Main text
• 41380_2020_Article_856.pdf

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Presenilins and γ-Secretase in Membrane Proteostasis.

Cells

Oikawa, Naoto N; Walter, Jochen J

Publication Date: 2019-03-01

Variant appearance in text: PS1: S367A

PubMed Link: 30823664

Variant Present in the following documents:

• Main text
• cells-08-00209.pdf

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Versatility of presenilin 1.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Frost, Georgia R GR; Wong, Eitan E; Li, Yue-Ming YM

Publication Date: 2017-07-03

Variant appearance in text: PS1: S367A

PubMed Link: 28645897

Variant Present in the following documents:

• Main text

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Bidirectional regulation of Aβ levels by Presenilin 1.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Bustos, Victor V; Pulina, Maria V MV; Kelahmetoglu, Yildiz Y; Sinha, Subhash C SC; Gorelick, Fred S FS; Flajolet, Marc M; Greengard, Paul P

Publication Date: 2017-07-03

Variant appearance in text: PS1: S367A

PubMed Link: 28533411

Variant Present in the following documents:

• Main text

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Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Bustos, Victor V; Pulina, Maria V MV; Bispo, Ashley A; Lam, Alison A; Flajolet, Marc M; Gorelick, Fred S FS; Greengard, Paul P

Publication Date: 2017-07-03

Variant appearance in text: PS1: S367A

PubMed Link: 28533369

Variant Present in the following documents:

• Main text

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Pathogenic PS1 phosphorylation at Ser367.

Elife

Maesako, Masato M; Horlacher, Jana J; Zoltowska, Katarzyna M KM; Kastanenka, Ksenia V KV; Kara, Eleanna E; Svirsky, Sarah S; Keller, Laura J LJ; Li, Xuejing X; Hyman, Bradley T BT; Bacskai, Brian J BJ; Berezovska, Oksana O

Publication Date: 2017-01-30

Variant appearance in text: PS1: S367A

PubMed Link: 28132667

Variant Present in the following documents:

• Main text
• elife-19720.pdf

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