Publications:

Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.

Oncotarget

Grigorenko, Anastasia P AP; Moliaka, Youri K YK; Plotnikova, Olga V OV; Smirnov, Alexander A; Nikishina, Vera A VA; Goltsov, Andrey Y AY; Gusev, Fedor F; Andreeva, Tatiana V TV; Nelson, Omar O; Bezprozvanny, Ilya I; Rogaev, Evgeny I EI

Publication Date: 2017-10-10

Variant appearance in text: PSEN1: D385E

PubMed Link: 29137240

Variant Present in the following documents:

• Main text
• oncotarget-08-82006-s001.pdf
• oncotarget-08-82006.pdf

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Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infection.

Journal Of Immunology (Baltimore, Md. : 1950)

Weyand, Nathan J NJ; Calton, Christine M CM; Higashi, Dustin L DL; Kanack, Kristen J KJ; So, Magdalene M

Publication Date: 2010-01-15

Variant appearance in text: PS1: D385E

PubMed Link: 20018629

Variant Present in the following documents:

• Main text

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Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates.

Molecular Neurodegeneration

Nyborg, Andrew C AC; Ladd, Thomas B TB; Zwizinski, Craig W CW; Lah, James J JJ; Golde, Todd E TE

Publication Date: 2006-06-12

Variant appearance in text: PS1: D385E

PubMed Link: 16930450

Variant Present in the following documents:

• Main text
• 1750-1326-1-3.pdf

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