Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex.
The Journal Of Biological Chemistry
Marinangeli, Claudia C; Tasiaux, Bernadette B; Opsomer, Rémi R; Hage, Salim S; Sodero, Alejandro O AO; Dewachter, Ilse I; Octave, Jean Noël JN; Smith, Steven O SO; Constantinescu, Stefan N SN; Kienlen-Campard, Pascal P