Hsp90 activator Aha1 drives production of pathological tau aggregates.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Shelton, Lindsey B LB; Baker, Jeremy D JD; Zheng, Dali D; Sullivan, Leia E LE; Solanki, Parth K PK; Webster, Jack M JM; Sun, Zheying Z; Sabbagh, Jonathan J JJ; Nordhues, Bryce A BA; Koren, John J; Ghosh, Suman S; Blagg, Brian S J BSJ; Blair, Laura J LJ; Dickey, Chad A CA
Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.
Molecular Biology Of The Cell
Koulov, Atanas V AV; LaPointe, Paul P; Lu, Bingwen B; Razvi, Abbas A; Coppinger, Judith J; Dong, Meng-Qiu MQ; Matteson, Jeanne J; Laister, Rob R; Arrowsmith, Cheryl C; Yates, John R JR; Balch, William E WE