Publications:

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Missense VKOR mutants exhibit severe warfarin resistance but lack VKCFD via shifting to an aberrantly reduced state.

Blood Advances

Li, Shuang S; Sun, Jie J; Liu, Shixuan S; Zhou, Fengbo F; Gross, Michael M; Li, Weikai W

Publication Date: 2022-12-12

Variant appearance in text: VKORC1: D36Y

PubMed Link: 36508285

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.

Frontiers In Pharmacology

Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Morel, Adrien A; Niño-Orrego, María José MJ; Ruiz-Torres, Daniel-Armando DA; Contreras Bravo, Nora Constanza NC; Restrepo, Carlos Martin CM; Ortega-Recalde, Oscar O; Fonseca-Mendoza, Dora Janeth DJ

Publication Date: 2022

Variant appearance in text: VKORC1: 106G>T; Asp36Tyr; rs61742245

PubMed Link: 35846994

Variant Present in the following documents:

• Table1.xlsx, sheet 1

View BVdb publication page

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Determination of Pleiotropic Effect of Warfarin in VKORC1 and CYP2C9 Genotypes in Patients With Heart Valve Replacement.

Frontiers In Cardiovascular Medicine

Shafique, Huma H; Ashraf, Naeem Mahmood NM; Rashid, Amir A; Majeed, Asifa A; Afsar, Tayyaba T; Daly, Ann K AK; Almajwal, Ali A; Alruwaili, Nawaf W NW; Khan, Azmat Ullah AU; Razak, Suhail S

Publication Date: 2022

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 35757332

Variant Present in the following documents:

• fcvm-09-895169.pdf

View BVdb publication page

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The Prevalence of Pharmacogenomics Variants and Their Clinical Relevance Among the Pakistani Population.

Evolutionary Bioinformatics Online

Khan, Abdul Rafay AR; Shah, Sayed Hajan SH; Ajaz, Sadia S; Firasat, Sadaf S; Abid, Aiysha A; Raza, Ali A

Publication Date: 2022

Variant appearance in text: VKORC1: D36Y

PubMed Link: 35497687

Variant Present in the following documents:

• 10.1177_11769343221095834.pdf

View BVdb publication page

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Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases.

Bmc Medical Genomics

Osman, Abdimajid A; Jonasson, Jon J

Publication Date: 2022-03-25

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 35337356

Variant Present in the following documents:

• Main text
• 12920_2022_Article_1220.pdf

View BVdb publication page

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Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.

Nature Neuroscience

Baxi, Emily G EG; Thompson, Terri T; Li, Jonathan J; Kaye, Julia A JA; Lim, Ryan G RG; Wu, Jie J; Ramamoorthy, Divya D; Lima, Leandro L; Vaibhav, Vineet V; Matlock, Andrea A; Frank, Aaron A; Coyne, Alyssa N AN; Landin, Barry B; Ornelas, Loren L; Mosmiller, Elizabeth E; Thrower, Sara S; Farr, S Michelle SM; Panther, Lindsey L; Gomez, Emilda E; Galvez, Erick E; Perez, Daniel D; Meepe, Imara I; Lei, Susan S; Mandefro, Berhan B; Trost, Hannah H; Pinedo, Louis L; Banuelos, Maria G MG; Liu, Chunyan C; Moran, Ruby R; Garcia, Veronica V; Workman, Michael M; Ho, Richie R; Wyman, Stacia S; Roggenbuck, Jennifer J; Harms, Matthew B MB; Stocksdale, Jennifer J; Miramontes, Ricardo R; Wang, Keona K; Venkatraman, Vidya V; Holewenski, Ronald R; Sundararaman, Niveda N; Pandey, Rakhi R; Manalo, Danica-Mae DM; Donde, Aneesh A; Huynh, Nhan N; Adam, Miriam M; Wassie, Brook T BT; Vertudes, Edward E; Amirani, Naufa N; Raja, Krishna K; Thomas, Reuben R; Hayes, Lindsey L; Lenail, Alex A; Cerezo, Aianna A; Luppino, Sarah S; Farrar, Alanna A; Pothier, Lindsay L; Prina, Carolyn C; Morgan, Todd T; Jamil, Arish A; Heintzman, Sarah S; Jockel-Balsarotti, Jennifer J; Karanja, Elizabeth E; Markway, Jesse J; McCallum, Molly M; Joslin, Ben B; Alibazoglu, Deniz D; Kolb, Stephen S; Ajroud-Driss, Senda S; Baloh, Robert R; Heitzman, Daragh D; Miller, Tim T; Glass, Jonathan D JD; Patel-Murray, Natasha Leanna NL; Yu, Hong H; Sinani, Ervin E; Vigneswaran, Prasha P; Sherman, Alexander V AV; Ahmad, Omar O; Roy, Promit P; Beavers, Jay C JC; Zeiler, Steven S; Krakauer, John W JW; Agurto, Carla C; Cecchi, Guillermo G; Bellard, Mary M; Raghav, Yogindra Y; Sachs, Karen K; Ehrenberger, Tobias T; Bruce, Elizabeth E; Cudkowicz, Merit E ME; Maragakis, Nicholas N; Norel, Raquel R; Van Eyk, Jennifer E JE; Finkbeiner, Steven S; Berry, James J; Sareen, Dhruv D; Thompson, Leslie M LM; Fraenkel, Ernest E; Svendsen, Clive N CN; Rothstein, Jeffrey D JD

Publication Date: 2022-02

Variant appearance in text: VKORC1: D36Y; rs61742245

PubMed Link: 35115730

Variant Present in the following documents:

• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 9
• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 7
• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 8

View BVdb publication page

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Identification of pharmacogenetic variants from large scale next generation sequencing data in the Saudi population.

Plos One

Goljan, Ewa E; Abouelhoda, Mohammed M; ElKalioby, Mohamed M MM; Jabaan, Amjad A; Alghithi, Nada N; Meyer, Brian F BF; Monies, Dorota D

Publication Date: 2022

Variant appearance in text: VKORC1: D36Y; rs61742245

PubMed Link: 35089958

Variant Present in the following documents:

• Main text
• pone.0263137.pdf
• pone.0263137.s001.xlsx, sheet 1

View BVdb publication page

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Left Ventricular Assist Device Pump Thrombosis in a Patient Treated with Apixaban.

The American Journal Of Case Reports

Alkhunaizi, Mansour A MA; Ali, Basim B

Publication Date: 2021-12-09

Variant appearance in text: VKORC1: ASP36TYR

PubMed Link: 34880201

Variant Present in the following documents:

• amjcaserep-22-e934787.pdf

View BVdb publication page

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A renal cell carcinoma tumorgraft platform to advance precision medicine.

Cell Reports

Elias, Roy R; Tcheuyap, Vanina T VT; Kaushik, Akash K AK; Singla, Nirmish N; Gao, Ming M; Reig Torras, Oscar O; Christie, Alana A; Mulgaonkar, Aditi A; Woolford, Layton L; Stevens, Christina C; Kettimuthu, Kavitha Priya KP; Pavia-Jimenez, Andrea A; Boroughs, Lindsey K LK; Joyce, Allison A; Dakanali, Marianna M; Notgrass, Hollis H; Margulis, Vitaly V; Cadeddu, Jeffrey A JA; Pedrosa, Ivan I; Williams, Noelle S NS; Sun, Xiankai X; DeBerardinis, Ralph J RJ; Öz, Orhan K OK; Zhong, Hua H; Seshagiri, Somasekar S; Modrusan, Zora Z; Cantarel, Brandi L BL; Kapur, Payal P; Brugarolas, James J

Publication Date: 2021-11-23

Variant appearance in text: VKORC1: 106G>T; D36Y; rs61742245

PubMed Link: 34818533

Variant Present in the following documents:

• NIHMS1761779-supplement-Table_S8.xlsx, sheet 1

View BVdb publication page

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A renal cell carcinoma tumorgraft platform to advance precision medicine.

Cell Reports

Elias, Roy R; Tcheuyap, Vanina T VT; Kaushik, Akash K AK; Singla, Nirmish N; Gao, Ming M; Reig Torras, Oscar O; Christie, Alana A; Mulgaonkar, Aditi A; Woolford, Layton L; Stevens, Christina C; Kettimuthu, Kavitha Priya KP; Pavia-Jimenez, Andrea A; Boroughs, Lindsey K LK; Joyce, Allison A; Dakanali, Marianna M; Notgrass, Hollis H; Margulis, Vitaly V; Cadeddu, Jeffrey A JA; Pedrosa, Ivan I; Williams, Noelle S NS; Sun, Xiankai X; DeBerardinis, Ralph J RJ; Öz, Orhan K OK; Zhong, Hua H; Seshagiri, Somasekar S; Modrusan, Zora Z; Cantarel, Brandi L BL; Kapur, Payal P; Brugarolas, James J

Publication Date: 2021-11-23

Variant appearance in text: VKORC1: 106G>T; D36Y; rs61742245

PubMed Link: 34818533

Variant Present in the following documents:

• NIHMS1761779-supplement-Table_S8.xlsx, sheet 1

View BVdb publication page

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Profiling of warfarin pharmacokinetics-associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics-dosing algorithm.

Journal Of Thrombosis And Haemostasis : Jth

Ndadza, Arinao A; Muyambo, Sarudzai S; Mntla, Pindile P; Wonkam, Ambroise A; Chimusa, Emile E; Kengne, Andre P AP; Ntsekhe, Mpiko M; Dandara, Collet C

Publication Date: 2021-12

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 34382722

Variant Present in the following documents:

• Main text
• JTH-19-2957.pdf

View BVdb publication page

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A study of elective genome sequencing and pharmacogenetic testing in an unselected population.

Molecular Genetics & Genomic Medicine

Cochran, Meagan M; East, Kelly K; Greve, Veronica V; Kelly, Melissa M; Kelley, Whitley W; Moore, Troy T; Myers, Richard M RM; Odom, Katherine K; Schroeder, Molly C MC; Bick, David D

Publication Date: 2021-09

Variant appearance in text: VKORC1: 106G>T; Asp36Tyr

PubMed Link: 34313030

Variant Present in the following documents:

• Main text
• MGG3-9-e1766.pdf

View BVdb publication page

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A study of elective genome sequencing and pharmacogenetic testing in an unselected population.

Molecular Genetics & Genomic Medicine

Cochran, Meagan M; East, Kelly K; Greve, Veronica V; Kelly, Melissa M; Kelley, Whitley W; Moore, Troy T; Myers, Richard M RM; Odom, Katherine K; Schroeder, Molly C MC; Bick, David D

Publication Date: 2021-09

Variant appearance in text: VKORC1: 106G>T; Asp36Tyr

PubMed Link: 34313030

Variant Present in the following documents:

• Main text
• MGG3-9-e1766.pdf

View BVdb publication page

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Gene variants of coagulation related proteins that interact with SARS-CoV-2.

Plos Computational Biology

Holcomb, David D; Alexaki, Aikaterini A; Hernandez, Nancy N; Hunt, Ryan R; Laurie, Kyle K; Kames, Jacob J; Hamasaki-Katagiri, Nobuko N; Komar, Anton A AA; DiCuccio, Michael M; Kimchi-Sarfaty, Chava C

Publication Date: 2021-03

Variant appearance in text: VKORC1: 106G>T

PubMed Link: 33730015

Variant Present in the following documents:

• Main text
• pcbi.1008805.pdf

View BVdb publication page

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Genetic Polymorphism Effect on Warfarin-Rifampin Interaction: A Case Report and Review of Literature.

Pharmacogenomics And Personalized Medicine

Salem, Muhammad M; Eljilany, Islam I; El-Bardissy, Ahmed A; Elewa, Hazem H

Publication Date: 2021

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 33542643

Variant Present in the following documents:

• Main text
• pgpm-14-149.pdf

View BVdb publication page

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Variation in 100 relevant pharmacogenes among emiratis with insights from understudied populations.

Scientific Reports

Al-Mahayri, Zeina N ZN; Patrinos, George P GP; Wattanapokayakit, Sukanya S; Iemwimangsa, Nareenart N; Fukunaga, Koya K; Mushiroda, Taisei T; Chantratita, Wasun W; Ali, Bassam R BR

Publication Date: 2020-12-04

Variant appearance in text: rs61742245

PubMed Link: 33277594

Variant Present in the following documents:

• Main text
• 41598_2020_Article_78231.pdf

View BVdb publication page

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Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2.

Biorxiv : The Preprint Server For Biology

Holcomb, David D; Alexaki, Aikaterini A; Hernandez, Nancy N; Laurie, Kyle K; Kames, Jacob J; Hamasaki-Katagiri, Nobuko N; Komar, Anton A AA; DiCuccio, Michael M; Kimchi-Sarfaty, Chava C

Publication Date: 2020-09-18

Variant appearance in text: VKORC1: 106G>T

PubMed Link: 32935103

Variant Present in the following documents:

• Main text

View BVdb publication page

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Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Clinical And Translational Science

Scott, Stuart A SA; Scott, Erick R ER; Seki, Yoshinori Y; Chen, Annette J AJ; Wallsten, Richard R; Owusu Obeng, Aniwaa A; Botton, Mariana R MR; Cody, Neal N; Shi, Huanzhi H; Zhao, Geping G; Brake, Paul P; Nicoletti, Paola P; Yang, Yao Y; Delio, Maria M; Shi, Lisong L; Kornreich, Ruth R; Schadt, Eric E EE; Edelmann, Lisa L

Publication Date: 2021-01

Variant appearance in text: VKORC1: 106G>T; rs61742245

PubMed Link: 32931151

Variant Present in the following documents:

• Main text
• CTS-14-204.pdf
• CTS-14-204-s001.xlsx, sheet 1
• CTS-14-204-s001.xlsx, sheet 4
• CTS-14-204-s001.xlsx, sheet 6

View BVdb publication page

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Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact.

Elife

Chiasson, Melissa A MA; Rollins, Nathan J NJ; Stephany, Jason J JJ; Sitko, Katherine A KA; Matreyek, Kenneth A KA; Verby, Marta M; Sun, Song S; Roth, Frederick P FP; DeSloover, Daniel D; Marks, Debora S DS; Rettie, Allan E AE; Fowler, Douglas M DM

Publication Date: 2020-09-01

Variant appearance in text: VKORC1: D36Y

PubMed Link: 32870157

Variant Present in the following documents:

• Main text
• elife-58026.pdf

View BVdb publication page

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Recommendations for Clinical Warfarin Genotyping Allele Selection: A Report of the Association for Molecular Pathology and the College of American Pathologists.

The Journal Of Molecular Diagnostics : Jmd

Pratt, Victoria M VM; Cavallari, Larisa H LH; Del Tredici, Andria L AL; Hachad, Houda H; Ji, Yuan Y; Kalman, Lisa V LV; Ly, Reynold C RC; Moyer, Ann M AM; Scott, Stuart A SA; Whirl-Carrillo, Michelle M; Weck, Karen E KE

Publication Date: 2020-07

Variant appearance in text: N/A

PubMed Link: 32380173

Variant Present in the following documents:

View BVdb publication page

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Role of Genetic Variations in the Hepatic Handling of Drugs.

International Journal Of Molecular Sciences

Marin, Jose J G JJG; Serrano, Maria A MA; Monte, Maria J MJ; Sanchez-Martin, Anabel A; Temprano, Alvaro G AG; Briz, Oscar O; Romero, Marta R MR

Publication Date: 2020-04-20

Variant appearance in text: VKORC1: 106G>T; Asp36Tyr; rs61742245

PubMed Link: 32326111

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-wide analyses disclose the distinctive HLA architecture and the pharmacogenetic landscape of the Somali population.

Scientific Reports

Ali, Abshir A AA; Aalto, Mikko M; Jonasson, Jon J; Osman, Abdimajid A

Publication Date: 2020-03-27

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 32221414

Variant Present in the following documents:

• Main text
• 41598_2020_Article_62645.pdf

View BVdb publication page

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A review of clinical pharmacogenetics Studies in African populations.

Personalized Medicine

Radouani, Fouzia F; Zass, Lyndon L; Hamdi, Yosr Y; Rocha, Jorge da JD; Sallam, Reem R; Abdelhak, Sonia S; Ahmed, Samah S; Azzouzi, Maryame M; Benamri, Ichrak I; Benkahla, Alia A; Bouhaouala-Zahar, Balkiss B; Chaouch, Melek M; Jmel, Haifa H; Kefi, Rym R; Ksouri, Ayoub A; Kumuthini, Judit J; Masilela, Phumlani P; Masimirembwa, Collen C; Othman, Houcemeddine H; Panji, Sumir S; Romdhane, Lilia L; Samtal, Chaimae C; Sibira, Rania R; Ghedira, Kais K; Fadlelmola, Faisal F; Kassim, Samar Kamal SK; Mulder, Nicola N

Publication Date: 2020-03

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 32125935

Variant Present in the following documents:

• Main text
• NIHMS1694746-supplement-Supplementary_file.xlsx, sheet 2
• nihms-1694746.pdf
• NIHMS1694746-supplement-Supplementary_file.xlsx, sheet 1

View BVdb publication page

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Oral Anticoagulant Therapy-When Art Meets Science.

Journal Of Clinical Medicine

Cîmpan, Patricia Lorena PL; Chira, Romeo Ioan RI; Mocan, Mihaela M; Anton, Florin Petru FP; Farcaş, Anca Daniela AD

Publication Date: 2019-10-21

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 31640208

Variant Present in the following documents:

• Main text
• jcm-08-01747.pdf

View BVdb publication page

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Pharmacogenomics.

Lancet (London, England)

Roden, Dan M DM; McLeod, Howard L HL; Relling, Mary V MV; Williams, Marc S MS; Mensah, George A GA; Peterson, Josh F JF; Van Driest, Sara L SL

Publication Date: 2019-08-10

Variant appearance in text: VKORC1: D36Y

PubMed Link: 31395440

Variant Present in the following documents:

• Main text

View BVdb publication page

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Population study of thrombophilic markers and pharmacogenetic markers of warfarin prevalence in Bosnia and Herzegovina.

Croatian Medical Journal

Ašić, Adna A; Salazar, Ramona R; Storm, Niels N; Doğan, Serkan S; Höppner, Wolfgang W; Marjanović, Damir D; Primorac, Dragan D

Publication Date: 2019-06-13

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 31187948

Variant Present in the following documents:

• Main text

View BVdb publication page

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VKORC1 variants as significant predictors of warfarin dose in Emiratis.

Pharmacogenomics And Personalized Medicine

Al-Mahayri, Zeina N ZN; Al Jaibeji, Hayat S HS; Saab, Yolande Y; Soliman, Karem K; Al-Gazali, Lihadh L; Patrinos, George P GP; Ali, Bassam R BR

Publication Date: 2019

Variant appearance in text: VKORC1: D36Y; rs61742245

PubMed Link: 31114289

Variant Present in the following documents:

• Main text
• pgpm-12-47.pdf

View BVdb publication page

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Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.

American Journal Of Human Genetics

Wright, Caroline F CF; West, Ben B; Tuke, Marcus M; Jones, Samuel E SE; Patel, Kashyap K; Laver, Thomas W TW; Beaumont, Robin N RN; Tyrrell, Jessica J; Wood, Andrew R AR; Frayling, Timothy M TM; Hattersley, Andrew T AT; Weedon, Michael N MN

Publication Date: 2019-02-07

Variant appearance in text: VKORC1: D36Y; rs61742245

PubMed Link: 30665703

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Impact of CYP2C9 and VKORC1 Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy.

Genes

Al-Eitan, Laith N LN; Almasri, Ayah Y AY; Khasawneh, Rame H RH

Publication Date: 2018-11-27

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 30486437

Variant Present in the following documents:

• Main text

View BVdb publication page

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Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics.

Scientific Reports

John, Sumi Elsa SE; Antony, Dinu D; Eaaswarkhanth, Muthukrishnan M; Hebbar, Prashantha P; Channanath, Arshad Mohamed AM; Thomas, Daisy D; Devarajan, Sriraman S; Tuomilehto, Jaakko J; Al-Mulla, Fahd F; Alsmadi, Osama O; Thanaraj, Thangavel Alphonse TA

Publication Date: 2018-11-08

Variant appearance in text: VKORC1: 106G>T; Asp36Tyr; rs61742245

PubMed Link: 30409984

Variant Present in the following documents:

• Main text
• 41598_2018_Article_34815.pdf

View BVdb publication page

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Pharmacogenetics of warfarin dosing in patients of African and European ancestry.

Pharmacogenomics

Shendre, Aditi A; Dillon, Chrisly C; Limdi, Nita A NA

Publication Date: 2018-11

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 30345882

Variant Present in the following documents:

• Main text

View BVdb publication page

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Opportunities and Challenges in Cardiovascular Pharmacogenomics: From Discovery to Implementation.

Circulation Research

Roden, Dan M DM; Van Driest, Sara L SL; Wells, Quinn S QS; Mosley, Jonathan D JD; Denny, Joshua C JC; Peterson, Josh F JF

Publication Date: 2018-04-27

Variant appearance in text: VKORC1: D36Y

PubMed Link: 29700066

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variation in human drug-related genes.

Genome Medicine

Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS

Publication Date: 2017-12-22

Variant appearance in text: rs61742245

PubMed Link: 29273096

Variant Present in the following documents:

• Main text
• 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
• 13073_2017_Article_502.pdf

View BVdb publication page

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VKORC1-1639A allele influences warfarin maintenance dosage among Blacks receiving warfarin anticoagulation: a retrospective cohort study.

Future Cardiology

Mili, Fatima Donia FD; Allen, Tenecia T; Wadell, Paula Weinstein PW; Hooper, W Craig WC; Staercke, Christine De C; Bean, Christopher J CJ; Lally, Cathy C; Austin, Harland H; Wenger, Nanette K NK

Publication Date: 2018-01

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 29218998

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai.

Pharmacogenomics

Scott, Stuart A SA; Owusu Obeng, Aniwaa A; Botton, Mariana R MR; Yang, Yao Y; Scott, Erick R ER; Ellis, Stephen B SB; Wallsten, Richard R; Kaszemacher, Tom T; Zhou, Xiang X; Chen, Rong R; Nicoletti, Paola P; Naik, Hetanshi H; Kenny, Eimear E EE; Vega, Aida A; Waite, Eva E; Diaz, George A GA; Dudley, Joel J; Halperin, Jonathan L JL; Edelmann, Lisa L; Kasarskis, Andrew A; Hulot, Jean-Sébastien JS; Peter, Inga I; Bottinger, Erwin P EP; Hirschhorn, Kurt K; Sklar, Pamela P; Cho, Judy H JH; Desnick, Robert J RJ; Schadt, Eric E EE

Publication Date: 2017-10

Variant appearance in text: VKORC1: D36Y

PubMed Link: 28982267

Variant Present in the following documents:

• Main text

View BVdb publication page

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Prevalence of common hereditary risk factors for thrombophilia in Somalia and identification of a novel Gln544Arg mutation in coagulation factor V.

Journal Of Thrombosis And Thrombolysis

Abdi, Abshir Ali AA; Osman, Abdimajid A

Publication Date: 2017-11

Variant appearance in text: VKORC1: Asp36Tyr; rs61742245

PubMed Link: 28889200

Variant Present in the following documents:

• Main text
• 11239_2017_Article_1543.pdf

View BVdb publication page

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Warfarin-induced life-threatening bleeding associated with a CYP3A4 loss-of-function mutation in an acute limb ischemia patient: Case report and review of the literature.

Experimental And Therapeutic Medicine

Ma, Xiao-Wei XW; Hao, Chang-Ning CN; Gu, Zhi-Chun ZC; Ye, Meng M; Li, Min M; Zhang, Lan L

Publication Date: 2017-08

Variant appearance in text: rs61742245

PubMed Link: 28810573

Variant Present in the following documents:

• Main text

View BVdb publication page

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Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S

Publication Date: 2017-10

Variant appearance in text: VKORC1: 106G>T; Asp36Tyr

PubMed Link: 28569743

Variant Present in the following documents:

• gim201760x7.xlsx, sheet 2

View BVdb publication page

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Differential analysis of mutations in the Jewish population and their implications for diseases.

Genetics Research

Einhorn, Yaron Y; Weissglas-Volkov, Daphna D; Carmi, Shai S; Ostrer, Harry H; Friedman, Eitan E; Shomron, Noam N

Publication Date: 2017-05-15

Variant appearance in text: rs61742245

PubMed Link: 28502252

Variant Present in the following documents:

• Main text
• S0016672317000015a.pdf

View BVdb publication page

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The Impact of Genetic and Non-Genetic Factors on Warfarin Dose Prediction in MENA Region: A Systematic Review.

Plos One

Bader, Loulia Akram LA; Elewa, Hazem H

Publication Date: 2016

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 27992547

Variant Present in the following documents:

• Main text
• pone.0168732.pdf

View BVdb publication page

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Pharmacogenetic Implementation Lessons From the "Real World".

Clinical Pharmacology And Therapeutics

Roden, D M DM

Publication Date: 2017-07

Variant appearance in text: VKORC1: D36Y

PubMed Link: 27981579

Variant Present in the following documents:

• Main text

View BVdb publication page

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Frequency of Common VKORC1 Polymorphisms and Their Impact on Warfarin Dose Requirement in Pakistani Population.

Clinical And Applied Thrombosis/Hemostasis : Official Journal Of The International Academy Of Clinical And Applied Thrombosis/Hemostasis

Qayyum, Aisha A; Najmi, Muzammil Hasan MH; Mansoor, Qaisar Q; Irfan, Muhammad M; Naveed, Abdul Khaliq AK; Hanif, Andleeb A; Kazmi, Ali Raza AR; Ismail, Muhammad M

Publication Date: 2018-03

Variant appearance in text: VKORC1: Asp36Tyr

PubMed Link: 27879469

Variant Present in the following documents:

• Main text

View BVdb publication page

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