Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.
Journal Of Medicinal Chemistry
Brand, Michael M; Clayton, James J; Moroglu, Mustafa M; Schiedel, Matthias M; Picaud, Sarah S; Bluck, Joseph P JP; Skwarska, Anna A; Bolland, Hannah H; Chan, Anthony K N AKN; Laurin, Corentine M C CMC; Scorah, Amy R AR; See, Larissa L; Rooney, Timothy P C TPC; Andrews, Katrina H KH; Fedorov, Oleg O; Perell, Gabriella G; Kalra, Prakriti P; Vinh, Kayla B KB; Cortopassi, Wilian A WA; Heitel, Pascal P; Christensen, Kirsten E KE; Cooper, Richard I RI; Paton, Robert S RS; Pomerantz, William C K WCK; Biggin, Philip C PC; Hammond, Ester M EM; Filippakopoulos, Panagis P; Conway, Stuart J SJ