FTO c.46-45529G>A

Variant ID: 16-53798523-G-A

NM_001080432.2(FTO):c.46-45529G>A

This variant was identified in 40 publications

View GRCh38 version.




Publications:


Impact of m6A demethylase (ALKBH5, FTO) genetic polymorphism and expression levels on the development of pulmonary tuberculosis.

Frontiers In Cellular And Infection Microbiology
Zhang, Tian-Ping TP; Li, Rui R; Wang, Li-Jun LJ; Li, Hong-Miao HM
Publication Date: 2022

Variant appearance in text: rs8047395
PubMed Link: 36619747
Variant Present in the following documents:
  • Main text
  • fcimb-12-1074380.pdf
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The effects of FTO gene rs9939609 polymorphism on the association between breast cancer and dietary intake.

Journal Of Cellular And Molecular Medicine
Doaei, Saeid S; Abdollahi, Sepideh S; Mohseni, Golsa Khalatbari GK; Gholamalizadeh, Maryam M; Akbari, Mohammad Esmail ME; Poorhosseini, Seyed Mohammad SM; Bagheri, Seyedeh Elaheh SE; Ghafouri-Fard, Soudeh S; Tabesh, Ghasem Azizi GA; Moslem, Alireza A; Hasanpour Ardekanizadeh, Naeemeh N; Omidi, Saeed S; Hekmatdoost, Azita A; Alam Rajabi, Mahdi M; Mosavi Jarrahi, Seyed Alireza SA; Goodarzi, Mark O MO
Publication Date: 2022-12

Variant appearance in text: rs8047395
PubMed Link: 36403211
Variant Present in the following documents:
  • Main text
  • JCMM-26-5794.pdf
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The controversial role and therapeutic development of the m6A demethylase FTO in renal cell carcinoma.

Translational Oncology
Zhang, Dalin D; Wornow, Sarah S; Peehl, Donna M DM; Rankin, Erinn B EB; Brooks, James D JD
Publication Date: 2022-11

Variant appearance in text: rs8047395
PubMed Link: 36037557
Variant Present in the following documents:
  • Main text
  • main.pdf
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The association of obesity with thyroid carcinoma risk.

Cancer Medicine
Ma, Xiao-Ni XN; Ma, Cheng-Xu CX; Hou, Li-Jie LJ; Fu, Song-Bo SB
Publication Date: 2022-02

Variant appearance in text: rs8047395
PubMed Link: 35032114
Variant Present in the following documents:
  • Main text
  • CAM4-11-1136.pdf
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Genetic Variants Associated with Thyroid Cancer Risk: Comprehensive Research Synopsis, Meta-Analysis, and Cumulative Epidemiological Evidence.

Journal Of Oncology
Ran, Ran R; Tu, Gang G; Li, Hui H; Wang, Hao H; Mou, Exian E; Liu, Caiyang C
Publication Date: 2021

Variant appearance in text: rs8047395
PubMed Link: 34950210
Variant Present in the following documents:
  • Main text
  • JO2021-9967599.pdf
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FTO Gene Polymorphisms Contribute to the Predisposition and Radiotherapy Efficiency of Nasopharyngeal Carcinoma.

Pharmacogenomics And Personalized Medicine
Xiao, Feng F; Zhou, Jianrong J
Publication Date: 2021

Variant appearance in text: rs8047395
PubMed Link: 34611423
Variant Present in the following documents:
  • Main text
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Roles of N6-Methyladenosine Demethylase FTO in Malignant Tumors Progression.

Oncotargets And Therapy
Zheng, Qing-Kang QK; Ma, Chao C; Ullah, Irfan I; Hu, Kang K; Ma, Rui-Jie RJ; Zhang, Nan N; Sun, Zhi-Gang ZG
Publication Date: 2021

Variant appearance in text: rs8047395
PubMed Link: 34556998
Variant Present in the following documents:
  • Main text
  • ott-14-4837.pdf
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Postmenopausal estrogen receptor positive breast cancer and obesity associated gene variants.

Excli Journal
Özgöz, Asuman A; Mutlu Içduygu, Fadime F; Yükseltürk, Aysegül A; Samli, Hale H; Hekimler Öztürk, Kuyas K; Baskan, Zuhal Z; Tütüncü, Ilknur I
Publication Date: 2021

Variant appearance in text: rs8047395
PubMed Link: 34345232
Variant Present in the following documents:
  • Main text
  • EXCLI-20-1133.pdf
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Integrative genomic analysis of N6-methyladenosine-single nucleotide polymorphisms (m6A-SNPs) associated with breast cancer.

Bioengineered
Xuan, Zixue Z; Zhang, Yiwen Y; Jiang, Jinying J; Zheng, Xiaowei X; Hu, Xiaoping X; Yang, Xiuli X; Shao, Yanfei Y; Zhang, Guobing G; Huang, Ping P
Publication Date: 2021-12

Variant appearance in text: rs8047395
PubMed Link: 34151731
Variant Present in the following documents:
  • Main text
  • KBIE_12_1935406.pdf
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Integrative genomic analysis of N6-methyladenosine-single nucleotide polymorphisms (m6A-SNPs) associated with breast cancer.

Bioengineered
Xuan, Zixue Z; Zhang, Yiwen Y; Jiang, Jinying J; Zheng, Xiaowei X; Hu, Xiaoping X; Yang, Xiuli X; Shao, Yanfei Y; Zhang, Guobing G; Huang, Ping P
Publication Date: 2021-12

Variant appearance in text: rs8047395
PubMed Link: 34151731
Variant Present in the following documents:
  • Main text
  • KBIE_12_1935406.pdf
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Statistical Impact of Sample Size and Imbalance on Multivariate Analysis in silico and A Case Study in the UK Biobank.

Amia ... Annual Symposium Proceedings. Amia Symposium
Zhang, Xinyuan X; Li, Ruowang R; Ritchie, Marylyn D MD
Publication Date: 2020

Variant appearance in text: rs8047395
PubMed Link: 33936514
Variant Present in the following documents:
  • Main text
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Genetic variants in m6A modification core genes are associated with glioma risk in Chinese children.

Molecular Therapy Oncolytics
He, Jing J; Yuan, Li L; Lin, Huiran H; Lin, Ao A; Chen, Huitong H; Luo, Ailing A; Zhuo, Zhenjian Z; Liu, Xiaoping X
Publication Date: 2021-03-26

Variant appearance in text: rs8047395
PubMed Link: 33665358
Variant Present in the following documents:
  • Main text
  • mmc2.pdf
  • main.pdf
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No Association Between FTO Gene Polymorphisms and Central Nervous System Tumor Susceptibility in Chinese Children.

Pharmacogenomics And Personalized Medicine
Liao, Yuxiang Y; Yuan, Li L; Zhang, Zhiping Z; Lin, Ao A; Zhou, Jingying J; Zhuo, Zhenjian Z; Zhao, Jie J
Publication Date: 2021

Variant appearance in text: rs8047395
PubMed Link: 33500652
Variant Present in the following documents:
  • Main text
  • pgpm-14-109.pdf
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The Potential Role of N6-Methyladenosine (m6A) Demethylase Fat Mass and Obesity-Associated Gene (FTO) in Human Cancers.

Oncotargets And Therapy
Wang, Jin-Yan JY; Chen, Li-Juan LJ; Qiang, Ping P
Publication Date: 2020

Variant appearance in text: rs8047395
PubMed Link: 33364780
Variant Present in the following documents:
  • Main text
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FTO - A Common Genetic Basis for Obesity and Cancer.

Frontiers In Genetics
Lan, Ning N; Lu, Ying Y; Zhang, Yigan Y; Pu, Shuangshuang S; Xi, Huaze H; Nie, Xin X; Liu, Jing J; Yuan, Wenzhen W
Publication Date: 2020

Variant appearance in text: rs8047395
PubMed Link: 33304380
Variant Present in the following documents:
  • Main text
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Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea.

Cancer Research And Treatment
Hoang, Tung T; Song, Dayoung D; Lee, Jeonghee J; Lee, Eun Kyung EK; Hwangbo, Yul Y; Kim, Jeongseon J
Publication Date: 2021-07

Variant appearance in text: rs8047395
PubMed Link: 33285050
Variant Present in the following documents:
  • Main text
  • crt-2020-720.pdf
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Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study.

Plos Medicine
Rogne, Tormod T; Solligård, Erik E; Burgess, Stephen S; Brumpton, Ben M BM; Paulsen, Julie J; Prescott, Hallie C HC; Mohus, Randi M RM; Gustad, Lise T LT; Mehl, Arne A; Åsvold, Bjørn O BO; DeWan, Andrew T AT; Damås, Jan K JK
Publication Date: 2020-11

Variant appearance in text: rs8047395
PubMed Link: 33196656
Variant Present in the following documents:
  • Main text
  • pmed.1003413.pdf
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Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I.Family study and meta-analysis.

Scientific Reports
Nagrani, Rajini R; Foraita, Ronja R; Gianfagna, Francesco F; Iacoviello, Licia L; Marild, Staffan S; Michels, Nathalie N; Molnár, Dénes D; Moreno, Luis L; Russo, Paola P; Veidebaum, Toomas T; Ahrens, Wolfgang W; Marron, Manuela M
Publication Date: 2020-04-28

Variant appearance in text: rs8047395
PubMed Link: 32346024
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_64031.pdf
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RNA N6-methyladenosine modification in solid tumors: new therapeutic frontiers.

Cancer Gene Therapy
Melstrom, Laleh L; Chen, Jianjun J
Publication Date: 2020-09

Variant appearance in text: rs8047395
PubMed Link: 31956264
Variant Present in the following documents:
  • Main text
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Erythropoietin (EPO) haplotype associated with all-cause mortality in a cohort of Italian patients with Type-2 Diabetes.

Scientific Reports
Montesanto, Alberto A; Bonfigli, Anna Rita AR; De Luca, Maria M; Crocco, Paolina P; Garagnani, Paolo P; Marasco, Elena E; Pirazzini, Chiara C; Giuliani, Cristina C; Romagnoli, Fabio F; Franceschi, Claudio C; Passarino, Giuseppe G; Testa, Roberto R; Olivieri, Fabiola F; Rose, Giuseppina G
Publication Date: 2019-07-17

Variant appearance in text: rs8047395
PubMed Link: 31316151
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_46894.pdf
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Critical Enzymatic Functions of FTO in Obesity and Cancer.

Frontiers In Endocrinology
Deng, Xiaolan X; Su, Rui R; Stanford, Savanna S; Chen, Jianjun J
Publication Date: 2018

Variant appearance in text: rs8047395
PubMed Link: 30105001
Variant Present in the following documents:
  • Main text
  • fendo-09-00396.pdf
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Fat Mass and Obesity-Associated (FTO) Gene Polymorphisms Are Associated with Risk of Intervertebral Disc Degeneration in Chinese Han Population: A Case Control Study.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Chen, Jia J; Zhu, Qiankun Q; Liu, Gang G; Yang, Xinzhuang X; Zhao, Sen S; Chen, Weisheng W; Wu, Zhihong Z; Wu, Nan N; Qiu, Guixing G
Publication Date: 2018-08-12

Variant appearance in text: rs8047395
PubMed Link: 30099472
Variant Present in the following documents:
  • Main text
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Genes associated with Type 2 Diabetes and vascular complications.

Aging
Montesanto, Alberto A; Bonfigli, Anna Rita AR; Crocco, Paolina P; Garagnani, Paolo P; De Luca, Maria M; Boemi, Massimo M; Marasco, Elena E; Pirazzini, Chiara C; Giuliani, Cristina C; Franceschi, Claudio C; Passarino, Giuseppe G; Testa, Roberto R; Olivieri, Fabiola F; Rose, Giuseppina G
Publication Date: 2018-02-04

Variant appearance in text: rs8047395
PubMed Link: 29410390
Variant Present in the following documents:
  • Main text
  • aging-10-101375.pdf
  • aging-10-101375-s001.pdf
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The (FTO) gene polymorphism is associated with metabolic syndrome risk in Egyptian females: a case- control study.

Bmc Medical Genetics
Khella, Mina S MS; Hamdy, Nadia M NM; Amin, Ashraf I AI; El-Mesallamy, Hala O HO
Publication Date: 2017-09-16

Variant appearance in text: rs8047395
PubMed Link: 28915859
Variant Present in the following documents:
  • Main text
  • 12881_2017_Article_461.pdf
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Lack of Association of the Fat Mass and Obesity Associated (FTO) Gene rs9939609 Polymorphism with Breast Cancer Risk: a Systematic Review and Meta-Analysis Based on Case - Control Studies

Asian Pacific Journal Of Cancer Prevention : Apjcp
Jafari Nedooshan, Jamal J; Kargar, Saeed S; Neamatzadeh, Hossein H; Haghighi, Fatemeh F; Dehghani Mohammad Abadi, Reihaneh R; Seddighi, Niloofar N
Publication Date: 2017-04-01

Variant appearance in text: rs8047395
PubMed Link: 28547937
Variant Present in the following documents:
  • Main text
  • APJCP-18-1031.pdf
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Selected single-nucleotide polymorphisms in FOXE1, SERPINA5, FTO, EVPL, TICAM1 and SCARB1 are associated with papillary and follicular thyroid cancer risk: replication study in a German population.

Carcinogenesis
Sigurdson, Alice J AJ; Brenner, Alina V AV; Roach, James A JA; Goudeva, Lilia L; Müller, Jörg A JA; Nerlich, Kai K; Reiners, Christoph C; Schwab, Robert R; Pfeiffer, Liliane L; Waldenberger, Melanie M; Braganza, Melissa M; Xu, Li L; Sturgis, Erich M EM; Yeager, Meredith M; Chanock, Stephen J SJ; Pfeiffer, Ruth M RM; Abend, Michael M; Port, Matthias M
Publication Date: 2016-07

Variant appearance in text: rs8047395
PubMed Link: 27207655
Variant Present in the following documents:
  • Main text
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Obesity and Breast Cancer: Molecular Interconnections and Potential Clinical Applications.

The Oncologist
Simone, Valeria V; D'Avenia, Morena M; Argentiero, Antonella A; Felici, Claudia C; Rizzo, Francesca Maria FM; De Pergola, Giovanni G; Silvestris, Franco F
Publication Date: 2016-04

Variant appearance in text: rs8047395
PubMed Link: 26865587
Variant Present in the following documents:
  • Main text
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Association of FTO Mutations with Risk and Survival of Breast Cancer in a Chinese Population.

Disease Markers
Zeng, Xianxu X; Ban, Zhenying Z; Cao, Jing J; Zhang, Wei W; Chu, Tianjiao T; Lei, Dongmei D; Du, Yanmin Y
Publication Date: 2015

Variant appearance in text: rs8047395
PubMed Link: 26146447
Variant Present in the following documents:
  • Main text
  • DM2015-101032.pdf
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Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs8047395
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
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Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups.

Plos One
Akiyama, Koichi K; Takeuchi, Fumihiko F; Isono, Masato M; Chakrawarthy, Sureka S; Nguyen, Quang Ngoc QN; Wen, Wanqing W; Yamamoto, Ken K; Katsuya, Tomohiro T; Kasturiratne, Anuradhani A; Pham, Son Thai ST; Zheng, Wei W; Matsushita, Yumi Y; Kishimoto, Miyako M; Do, Loi Doan LD; Shu, Xiao-Ou XO; Wickremasinghe, Ananda R AR; Kajio, Hiroshi H; Kato, Norihiro N
Publication Date: 2014

Variant appearance in text: rs8047395
PubMed Link: 24978468
Variant Present in the following documents:
  • Main text
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Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

Plos One
Tan, Li-Jun LJ; Zhu, Hu H; He, Hao H; Wu, Ke-Hao KH; Li, Jian J; Chen, Xiang-Ding XD; Zhang, Ji-Gang JG; Shen, Hui H; Tian, Qing Q; Krousel-Wood, Marie M; Papasian, Christopher J CJ; Bouchard, Claude C; Pérusse, Louis L; Deng, Hong-Wen HW
Publication Date: 2014

Variant appearance in text: rs8047395
PubMed Link: 24879436
Variant Present in the following documents:
  • Main text
  • pone.0096149.pdf
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Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs8047395
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
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Clinical and genetic predictors of weight gain in patients diagnosed with breast cancer.

British Journal Of Cancer
Reddy, S M SM; Sadim, M M; Li, J J; Yi, N N; Agarwal, S S; Mantzoros, C S CS; Kaklamani, V G VG
Publication Date: 2013-08-20

Variant appearance in text: rs8047395
PubMed Link: 23922112
Variant Present in the following documents:
  • Main text
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Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes.

Aging
Garagnani, Paolo P; Giuliani, Cristina C; Pirazzini, Chiara C; Olivieri, Fabiola F; Bacalini, Maria Giulia MG; Ostan, Rita R; Mari, Daniela D; Passarino, Giuseppe G; Monti, Daniela D; Bonfigli, Anna Rita AR; Boemi, Massimo M; Ceriello, Antonio A; Genovese, Stefano S; Sevini, Federica F; Luiselli, Donata D; Tieri, Paolo P; Capri, Miriam M; Salvioli, Stefano S; Vijg, Jan J; Suh, Yousin Y; Delledonne, Massimo M; Testa, Roberto R; Franceschi, Claudio C
Publication Date: 2013-05

Variant appearance in text: rs8047395
PubMed Link: 23804578
Variant Present in the following documents:
  • Main text
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Genome-wide association analysis implicates elastic microfibrils in the development of nonsyndromic striae distensae.

The Journal Of Investigative Dermatology
Tung, Joyce Y JY; Kiefer, Amy K AK; Mullins, Meghan M; Francke, Uta U; Eriksson, Nicholas N
Publication Date: 2013-11

Variant appearance in text: rs8047395
PubMed Link: 23633020
Variant Present in the following documents:
  • jid2013196x1.pdf
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Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis.

Molecular Biology Reports
Wang, Haina H; Dong, Shuqian S; Xu, Hui H; Qian, Jun J; Yang, Jingyun J
Publication Date: 2012-05

Variant appearance in text: rs8047395
PubMed Link: 22189543
Variant Present in the following documents:
  • Main text
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The role of the fat mass and obesity associated gene (FTO) in breast cancer risk.

Bmc Medical Genetics
Kaklamani, Virginia V; Yi, Nengjun N; Sadim, Maureen M; Siziopikou, Kalliopi K; Zhang, Kui K; Xu, Yanfei Y; Tofilon, Sarah S; Agarwal, Surbhi S; Pasche, Boris B; Mantzoros, Christos C
Publication Date: 2011-04-13

Variant appearance in text: rs8047395
PubMed Link: 21489227
Variant Present in the following documents:
  • Main text
  • 1471-2350-12-52.pdf
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Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

International Journal Of Obesity (2005)
Wing, M R MR; Ziegler, J M JM; Langefeld, C D CD; Roh, B H BH; Palmer, N D ND; Mayer-Davis, E J EJ; Rewers, M J MJ; Haffner, S M SM; Wagenknecht, L E LE; Bowden, D W DW
Publication Date: 2011-09

Variant appearance in text: rs8047395
PubMed Link: 21102551
Variant Present in the following documents:
  • Main text
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Fine mapping of the association with obesity at the FTO locus in African-derived populations.

Human Molecular Genetics
Hassanein, Mohamed T MT; Lyon, Helen N HN; Nguyen, Thutrang T TT; Akylbekova, Ermeg L EL; Waters, Kevin K; Lettre, Guillaume G; Tayo, Bamidele B; Forrester, Terrence T; Sarpong, Daniel F DF; Stram, Dan O DO; Butler, Johannah L JL; Wilks, Rainford R; Liu, Jiankang J; Le Marchand, Loic L; Kolonel, Laurence N LN; Zhu, Xiaofeng X; Henderson, Brian B; Cooper, Richard R; McKenzie, Colin C; Taylor, Herman A HA; Haiman, Christopher A CA; Hirschhorn, Joel N JN
Publication Date: 2010-07-15

Variant appearance in text: rs8047395
PubMed Link: 20430937
Variant Present in the following documents:
  • Main text
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Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types.

Evidence-Based Complementary And Alternative Medicine : Ecam
Cha, Seongwon S; Koo, Imhoi I; Park, Byung L BL; Jeong, Sangkyun S; Choi, Sun M SM; Kim, Kil S KS; Shin, Hyoung D HD; Kim, Jong Y JY
Publication Date: 2011

Variant appearance in text: rs8047395
PubMed Link: 19822564
Variant Present in the following documents:
  • ECAM2011-106390.pdf
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