FTO c.46-44545G>A

Variant ID: 16-53799507-G-A

NM_001080432.2(FTO):c.46-44545G>A

This variant was identified in 18 publications

View GRCh38 version.




Publications:


Emerging Role and Mechanism of the FTO Gene in Cardiovascular Diseases.

Biomolecules
Xu, Zi-Yang ZY; Jing, Xia X; Xiong, Xing-Dong XD
Publication Date: 2023-05-17

Variant appearance in text: rs9937053
PubMed Link: 37238719
Variant Present in the following documents:
  • Main text
  • biomolecules-13-00850.pdf
View BVdb publication page



Causal Relations Between Obstructive Sleep Apnea and Stroke: A Mendelian Randomization Study.

Nature And Science Of Sleep
Li, Po P; Dong, Zhiyong Z; Chen, Wenhui W; Yang, Gang G
Publication Date: 2023

Variant appearance in text: rs9937053
PubMed Link: 37155472
Variant Present in the following documents:
  • Main text
  • nss-15-257.pdf
View BVdb publication page



Comprehensive Analysis of N6-Methyladenosine Regulators in the Subcluster Classification and Drug Candidates Prediction of Severe Obstructive Sleep Apnea.

Frontiers In Genetics
Li, Niannian N; Gao, Zhenfei Z; Shen, Jinhong J; Liu, Yuenan Y; Wu, Kejia K; Yang, Jundong J; Wang, Shengming S; Zhang, Xiaoman X; Zhu, Yaxin Y; Zhu, Jingyu J; Guan, Jian J; Liu, Feng F; Yin, Shankai S
Publication Date: 2022

Variant appearance in text: rs9937053
PubMed Link: 35559050
Variant Present in the following documents:
  • Main text
  • fgene-13-862972.pdf
View BVdb publication page



Assessment of the Causal Effects of Obstructive Sleep Apnea on Atrial Fibrillation: A Mendelian Randomization Study.

Frontiers In Cardiovascular Medicine
Li, Yalan Y; Leng, Yiming Y; Tang, Haibo H; Deng, Peizhi P; Wang, Jie J; Yuan, Hong H; Miao, Rujia R; Mu, Ping P
Publication Date: 2022

Variant appearance in text: rs9937053
PubMed Link: 35224066
Variant Present in the following documents:
  • Main text
  • fcvm-09-843681.pdf
View BVdb publication page



Causal Effect of Obstructive Sleep Apnea on Atrial Fibrillation: A Mendelian Randomization Study.

Journal Of The American Heart Association
Chen, Weiqi W; Cai, Xueli X; Yan, Hongyi H; Pan, Yuesong Y
Publication Date: 2021-12-07

Variant appearance in text: rs9937053
PubMed Link: 34796736
Variant Present in the following documents:
  • Main text
  • JAH3-10-e022560.pdf
View BVdb publication page



Shared genetic etiology and causality between body fat percentage and cardiovascular diseases: a large-scale genome-wide cross-trait analysis.

Bmc Medicine
Zhuang, Zhenhuang Z; Yao, Minhao M; Wong, Jason Y Y JYY; Liu, Zhonghua Z; Huang, Tao T
Publication Date: 2021-04-29

Variant appearance in text: rs9937053
PubMed Link: 33910581
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea.

Cancer Research And Treatment
Hoang, Tung T; Song, Dayoung D; Lee, Jeonghee J; Lee, Eun Kyung EK; Hwangbo, Yul Y; Kim, Jeongseon J
Publication Date: 2021-07

Variant appearance in text: rs9937053
PubMed Link: 33285050
Variant Present in the following documents:
  • Main text
  • crt-2020-720.pdf
View BVdb publication page



CAUSALdb: a database for disease/trait causal variants identified using summary statistics of genome-wide association studies.

Nucleic Acids Research
Wang, Jianhua J; Huang, Dandan D; Zhou, Yao Y; Yao, Hongcheng H; Liu, Huanhuan H; Zhai, Sinan S; Wu, Chengwei C; Zheng, Zhanye Z; Zhao, Ke K; Wang, Zhao Z; Yi, Xianfu X; Zhang, Shijie S; Liu, Xiaorong X; Liu, Zipeng Z; Chen, Kexin K; Yu, Ying Y; Sham, Pak Chung PC; Li, Mulin Jun MJ
Publication Date: 2020-01-08

Variant appearance in text: rs9937053
PubMed Link: 31691819
Variant Present in the following documents:
  • Main text
  • gkz1026.pdf
View BVdb publication page



New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.

Nature Communications
Lu, Yingchang Y; Day, Felix R FR; Gustafsson, Stefan S; Buchkovich, Martin L ML; Na, Jianbo J; Bataille, Veronique V; Cousminer, Diana L DL; Dastani, Zari Z; Drong, Alexander W AW; Esko, Tõnu T; Evans, David M DM; Falchi, Mario M; Feitosa, Mary F MF; Ferreira, Teresa T; Hedman, Åsa K ÅK; Haring, Robin R; Hysi, Pirro G PG; Iles, Mark M MM; Justice, Anne E AE; Kanoni, Stavroula S; Lagou, Vasiliki V; Li, Rui R; Li, Xin X; Locke, Adam A; Lu, Chen C; Mägi, Reedik R; Perry, John R B JR; Pers, Tune H TH; Qi, Qibin Q; Sanna, Marianna M; Schmidt, Ellen M EM; Scott, William R WR; Shungin, Dmitry D; Teumer, Alexander A; Vinkhuyzen, Anna A E AA; Walker, Ryan W RW; Westra, Harm-Jan HJ; Zhang, Mingfeng M; Zhang, Weihua W; Zhao, Jing Hua JH; Zhu, Zhihong Z; Afzal, Uzma U; Ahluwalia, Tarunveer Singh TS; Bakker, Stephan J L SJ; Bellis, Claire C; Bonnefond, Amélie A; Borodulin, Katja K; Buchman, Aron S AS; Cederholm, Tommy T; Choh, Audrey C AC; Choi, Hyung Jin HJ; Curran, Joanne E JE; de Groot, Lisette C P G M LC; De Jager, Philip L PL; Dhonukshe-Rutten, Rosalie A M RA; Enneman, Anke W AW; Eury, Elodie E; Evans, Daniel S DS; Forsen, Tom T; Friedrich, Nele N; Fumeron, Frédéric F; Garcia, Melissa E ME; Gärtner, Simone S; Han, Bok-Ghee BG; Havulinna, Aki S AS; Hayward, Caroline C; Hernandez, Dena D; Hillege, Hans H; Ittermann, Till T; Kent, Jack W JW; Kolcic, Ivana I; Laatikainen, Tiina T; Lahti, Jari J; Mateo Leach, Irene I; Lee, Christine G CG; Lee, Jong-Young JY; Liu, Tian T; Liu, Youfang Y; Lobbens, Stéphane S; Loh, Marie M; Lyytikäinen, Leo-Pekka LP; Medina-Gomez, Carolina C; Michaëlsson, Karl K; Nalls, Mike A MA; Nielson, Carrie M CM; Oozageer, Laticia L; Pascoe, Laura L; Paternoster, Lavinia L; Polašek, Ozren O; Ripatti, Samuli S; Sarzynski, Mark A MA; Shin, Chan Soo CS; Narančić, Nina Smolej NS; Spira, Dominik D; Srikanth, Priya P; Steinhagen-Thiessen, Elisabeth E; Sung, Yun Ju YJ; Swart, Karin M A KM; Taittonen, Leena L; Tanaka, Toshiko T; Tikkanen, Emmi E; van der Velde, Nathalie N; van Schoor, Natasja M NM; Verweij, Niek N; Wright, Alan F AF; Yu, Lei L; Zmuda, Joseph M JM; Eklund, Niina N; Forrester, Terrence T; Grarup, Niels N; Jackson, Anne U AU; Kristiansson, Kati K; Kuulasmaa, Teemu T; Kuusisto, Johanna J; Lichtner, Peter P; Luan, Jian'an J; Mahajan, Anubha A; Männistö, Satu S; Palmer, Cameron D CD; Ried, Janina S JS; Scott, Robert A RA; Stancáková, Alena A; Wagner, Peter J PJ; Demirkan, Ayse A; Döring, Angela A; Gudnason, Vilmundur V; Kiel, Douglas P DP; Kühnel, Brigitte B; Mangino, Massimo M; Mcknight, Barbara B; Menni, Cristina C; O'Connell, Jeffrey R JR; Oostra, Ben A BA; Shuldiner, Alan R AR; Song, Kijoung K; Vandenput, Liesbeth L; van Duijn, Cornelia M CM; Vollenweider, Peter P; White, Charles C CC; Boehnke, Michael M; Boettcher, Yvonne Y; Cooper, Richard S RS; Forouhi, Nita G NG; Gieger, Christian C; Grallert, Harald H; Hingorani, Aroon A; Jørgensen, Torben T; Jousilahti, Pekka P; Kivimaki, Mika M; Kumari, Meena M; Laakso, Markku M; Langenberg, Claudia C; Linneberg, Allan A; Luke, Amy A; Mckenzie, Colin A CA; Palotie, Aarno A; Pedersen, Oluf O; Peters, Annette A; Strauch, Konstantin K; Tayo, Bamidele O BO; Wareham, Nicholas J NJ; Bennett, David A DA; Bertram, Lars L; Blangero, John J; Blüher, Matthias M; Bouchard, Claude C; Campbell, Harry H; Cho, Nam H NH; Cummings, Steven R SR; Czerwinski, Stefan A SA; Demuth, Ilja I; Eckardt, Rahel R; Eriksson, Johan G JG; Ferrucci, Luigi L; Franco, Oscar H OH; Froguel, Philippe P; Gansevoort, Ron T RT; Hansen, Torben T; Harris, Tamara B TB; Hastie, Nicholas N; Heliövaara, Markku M; Hofman, Albert A; Jordan, Joanne M JM; Jula, Antti A; Kähönen, Mika M; Kajantie, Eero E; Knekt, Paul B PB; Koskinen, Seppo S; Kovacs, Peter P; Lehtimäki, Terho T; Lind, Lars L; Liu, Yongmei Y; Orwoll, Eric S ES; Osmond, Clive C; Perola, Markus M; Pérusse, Louis L; Raitakari, Olli T OT; Rankinen, Tuomo T; Rao, D C DC; Rice, Treva K TK; Rivadeneira, Fernando F; Rudan, Igor I; Salomaa, Veikko V; Sørensen, Thorkild I A TI; Stumvoll, Michael M; Tönjes, Anke A; Towne, Bradford B; Tranah, Gregory J GJ; Tremblay, Angelo A; Uitterlinden, André G AG; van der Harst, Pim P; Vartiainen, Erkki E; Viikari, Jorma S JS; Vitart, Veronique V; Vohl, Marie-Claude MC; Völzke, Henry H; Walker, Mark M; Wallaschofski, Henri H; Wild, Sarah S; Wilson, James F JF; Yengo, Loïc L; Bishop, D Timothy DT; Borecki, Ingrid B IB; Chambers, John C JC; Cupples, L Adrienne LA; Dehghan, Abbas A; Deloukas, Panos P; Fatemifar, Ghazaleh G; Fox, Caroline C; Furey, Terrence S TS; Franke, Lude L; Han, Jiali J; Hunter, David J DJ; Karjalainen, Juha J; Karpe, Fredrik F; Kaplan, Robert C RC; Kooner, Jaspal S JS; McCarthy, Mark I MI; Murabito, Joanne M JM; Morris, Andrew P AP; Bishop, Julia A N JA; North, Kari E KE; Ohlsson, Claes C; Ong, Ken K KK; Prokopenko, Inga I; Richards, J Brent JB; Schadt, Eric E EE; Spector, Tim D TD; Widén, Elisabeth E; Willer, Cristen J CJ; Yang, Jian J; Ingelsson, Erik E; Mohlke, Karen L KL; Hirschhorn, Joel N JN; Pospisilik, John Andrew JA; Zillikens, M Carola MC; Lindgren, Cecilia C; Kilpeläinen, Tuomas Oskari TO; Loos, Ruth J F RJ
Publication Date: 2016-02-01

Variant appearance in text: rs9937053
PubMed Link: 26833246
Variant Present in the following documents:
  • ncomms10495-s1.pdf
View BVdb publication page



Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs9937053
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
  • fgene-05-00250.pdf
View BVdb publication page



Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs9937053
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



The FTO gene rs9939609 polymorphism predicts risk of cardiovascular disease: a systematic review and meta-analysis.

Plos One
Liu, Chibo C; Mou, Sihua S; Pan, Chunqin C
Publication Date: 2013

Variant appearance in text: rs9937053
PubMed Link: 23977173
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association analysis implicates elastic microfibrils in the development of nonsyndromic striae distensae.

The Journal Of Investigative Dermatology
Tung, Joyce Y JY; Kiefer, Amy K AK; Mullins, Meghan M; Francke, Uta U; Eriksson, Nicholas N
Publication Date: 2013-11

Variant appearance in text: rs9937053
PubMed Link: 23633020
Variant Present in the following documents:
  • jid2013196x1.pdf
View BVdb publication page



Evaluation of the obesity genes FTO and MC4R and the type 2 diabetes mellitus gene TCF7L2 for contribution to stroke risk: The Mannheim-Heidelberg Stroke Study.

Obesity Facts
Winter, Yaroslav Y; Back, Tobias T; Scherag, André A; Linseisen, Jakob J; Rohrmann, Sabine S; Lanczik, Oliver O; Hinney, Anke A; Scherag, Susann S; Neumaier, Michael M; Ringleb, Peter A PA; Dodel, Richard R; Hebebrand, Johannes J
Publication Date: 2011

Variant appearance in text: rs9937053
PubMed Link: 21921652
Variant Present in the following documents:
  • Main text
View BVdb publication page



A genome-wide association study on obesity and obesity-related traits.

Plos One
Wang, Kai K; Li, Wei-Dong WD; Zhang, Clarence K CK; Wang, Zuoheng Z; Glessner, Joseph T JT; Grant, Struan F A SF; Zhao, Hongyu H; Hakonarson, Hakon H; Price, R Arlen RA
Publication Date: 2011-04-28

Variant appearance in text: rs9937053
PubMed Link: 21552555
Variant Present in the following documents:
  • Main text
  • pone.0018939.pdf
View BVdb publication page



Variations in the FTO gene are associated with severe obesity in the Japanese.

Journal Of Human Genetics
Hotta, Kikuko K; Nakata, Yoshio Y; Matsuo, Tomoaki T; Kamohara, Seika S; Kotani, Kazuaki K; Komatsu, Ryoya R; Itoh, Naoto N; Mineo, Ikuo I; Wada, Jun J; Masuzaki, Hiroaki H; Yoneda, Masato M; Nakajima, Atsushi A; Miyazaki, Shigeru S; Tokunaga, Katsuto K; Kawamoto, Manabu M; Funahashi, Tohru T; Hamaguchi, Kazuyuki K; Yamada, Kentaro K; Hanafusa, Toshiaki T; Oikawa, Shinichi S; Yoshimatsu, Hironobu H; Nakao, Kazuwa K; Sakata, Toshiie T; Matsuzawa, Yuji Y; Tanaka, Kiyoji K; Kamatani, Naoyuki N; Nakamura, Yusuke Y
Publication Date: 2008

Variant appearance in text: rs9937053
PubMed Link: 18379722
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Plos Genetics
Scuteri, Angelo A; Sanna, Serena S; Chen, Wei-Min WM; Uda, Manuela M; Albai, Giuseppe G; Strait, James J; Najjar, Samer S; Nagaraja, Ramaiah R; Orrú, Marco M; Usala, Gianluca G; Dei, Mariano M; Lai, Sandra S; Maschio, Andrea A; Busonero, Fabio F; Mulas, Antonella A; Ehret, Georg B GB; Fink, Ashley A AA; Weder, Alan B AB; Cooper, Richard S RS; Galan, Pilar P; Chakravarti, Aravinda A; Schlessinger, David D; Cao, Antonio A; Lakatta, Edward E; Abecasis, Gonçalo R GR
Publication Date: 2007-07

Variant appearance in text: rs9937053
PubMed Link: 17658951
Variant Present in the following documents:
  • pgen.0030115.pdf
View BVdb publication page