Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population.
Genes
Chama-Avilés, Alonso A; Flores-Viveros, Karla Lucero KL; Cabrera-Ayala, Jorge Alberto JA; Aguilar-Galarza, Adriana A; García-Muñoz, Willebaldo W; Haddad-Talancón, Lorenza L; de Lourdes Anzures-Cortés, Ma M; Velázquez-Sánchez, Claudia C; Chávez-Servín, Jorge Luis JL; Anaya-Loyola, Miriam Aracely MA; García-Gasca, Teresa T; Rodríguez-García, Víctor Manuel VM; Moreno-Celis, Ulisses U
Genetic Studies of Metabolic Syndrome in Arab Populations: A Systematic Review and Meta-Analysis.
Frontiers In Genetics
Al-Homedi, Zahrah Z; Afify, Nariman N; Memon, Mashal M; Alsafar, Habiba H; Tay, Guan G; Jelinek, Herbert F HF; Mousa, Mira M; Abu-Samra, Nadia N; Osman, Wael W
Differential effects on neurodevelopment of FTO variants in obesity and bipolar disorder suggested by in silico prediction of functional impact: An analysis in Mexican population.
Brain And Behavior
Saucedo-Uribe, Erasmo E; Genis-Mendoza, Alma Delia AD; Díaz-Anzaldúa, Adriana A; Martínez-Magaña, José Jaime JJ; Tovilla-Zarate, Carlos Alfonso CA; Juárez-Rojop, Isela I; Lanzagorta, Nuria N; Escamilla, Michael M; González-Castro, Thelma Beatriz TB; López Narvaez, María Lilia ML; Hernández-Díaz, Yazmín Y; Nicolini, Humberto H
Influence of FTO rs9939609 and Mediterranean diet on body composition and weight loss: a randomized clinical trial.
Journal Of Translational Medicine
Di Renzo, Laura L; Cioccoloni, Giorgia G; Falco, Simone S; Abenavoli, Ludovico L; Moia, Alessandra A; Sinibaldi Salimei, Paola P; De Lorenzo, Antonino A
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
Nature Communications
McDaid, Aaron F AF; Joshi, Peter K PK; Porcu, Eleonora E; Komljenovic, Andrea A; Li, Hao H; Sorrentino, Vincenzo V; Litovchenko, Maria M; Bevers, Roel P J RPJ; Rüeger, Sina S; Reymond, Alexandre A; Bochud, Murielle M; Deplancke, Bart B; Williams, Robert W RW; Robinson-Rechavi, Marc M; Paccaud, Fred F; Rousson, Valentin V; Auwerx, Johan J; Wilson, James F JF; Kutalik, Zoltán Z
Assessing the Causality Factors in the Association between (Abdominal) Obesity and Physical Activity among the Newfoundland Population-A Mendelian Randomization Analysis.
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Nature Genetics
Gaulton, Kyle J KJ; Ferreira, Teresa T; Lee, Yeji Y; Raimondo, Anne A; Mägi, Reedik R; Reschen, Michael E ME; Mahajan, Anubha A; Locke, Adam A; Rayner, N William NW; Robertson, Neil N; Scott, Robert A RA; Prokopenko, Inga I; Scott, Laura J LJ; Green, Todd T; Sparso, Thomas T; Thuillier, Dorothee D; Yengo, Loic L; Grallert, Harald H; Wahl, Simone S; Frånberg, Mattias M; Strawbridge, Rona J RJ; Kestler, Hans H; Chheda, Himanshu H; Eisele, Lewin L; Gustafsson, Stefan S; Steinthorsdottir, Valgerdur V; Thorleifsson, Gudmar G; Qi, Lu L; Karssen, Lennart C LC; van Leeuwen, Elisabeth M EM; Willems, Sara M SM; Li, Man M; Chen, Han H; Fuchsberger, Christian C; Kwan, Phoenix P; Ma, Clement C; Linderman, Michael M; Lu, Yingchang Y; Thomsen, Soren K SK; Rundle, Jana K JK; Beer, Nicola L NL; van de Bunt, Martijn M; Chalisey, Anil A; Kang, Hyun Min HM; Voight, Benjamin F BF; Abecasis, Gonçalo R GR; Almgren, Peter P; Baldassarre, Damiano D; Balkau, Beverley B; Benediktsson, Rafn R; Blüher, Matthias M; Boeing, Heiner H; Bonnycastle, Lori L LL; Bottinger, Erwin P EP; Burtt, Noël P NP; Carey, Jason J; Charpentier, Guillaume G; Chines, Peter S PS; Cornelis, Marilyn C MC; Couper, David J DJ; Crenshaw, Andrew T AT; van Dam, Rob M RM; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Eriksson, Johan G JG; Esko, Tonu T; Eury, Elodie E; Fadista, João J; Flannick, Jason J; Fontanillas, Pierre P; Fox, Caroline C; Franks, Paul W PW; Gertow, Karl K; Gieger, Christian C; Gigante, Bruna B; Gottesman, Omri O; Grant, George B GB; Grarup, Niels N; Groves, Christopher J CJ; Hassinen, Maija M; Have, Christian T CT; Herder, Christian C; Holmen, Oddgeir L OL; Hreidarsson, Astradur B AB; Humphries, Steve E SE; Hunter, David J DJ; Jackson, Anne U AU; Jonsson, Anna A; Jørgensen, Marit E ME; Jørgensen, Torben T; Kao, Wen-Hong L WH; Kerrison, Nicola D ND; Kinnunen, Leena L; Klopp, Norman N; Kong, Augustine A; Kovacs, Peter P; Kraft, Peter P; Kravic, Jasmina J; Langford, Cordelia C; Leander, Karin K; Liang, Liming L; Lichtner, Peter P; Lindgren, Cecilia M CM; Lindholm, Eero E; Linneberg, Allan A; Liu, Ching-Ti CT; Lobbens, Stéphane S; Luan, Jian'an J; Lyssenko, Valeriya V; Männistö, Satu S; McLeod, Olga O; Meyer, Julia J; Mihailov, Evelin E; Mirza, Ghazala G; Mühleisen, Thomas W TW; Müller-Nurasyid, Martina M; Navarro, Carmen C; Nöthen, Markus M MM; Oskolkov, Nikolay N NN; Owen, Katharine R KR; Palli, Domenico D; Pechlivanis, Sonali S; Peltonen, Leena L; Perry, John R B JR; Platou, Carl G P CG; Roden, Michael M; Ruderfer, Douglas D; Rybin, Denis D; van der Schouw, Yvonne T YT; Sennblad, Bengt B; Sigurðsson, Gunnar G; Stančáková, Alena A; Steinbach, Gerald G; Storm, Petter P; Strauch, Konstantin K; Stringham, Heather M HM; Sun, Qi Q; Thorand, Barbara B; Tikkanen, Emmi E; Tonjes, Anke A; Trakalo, Joseph J; Tremoli, Elena E; Tuomi, Tiinamaija T; Wennauer, Roman R; Wiltshire, Steven S; Wood, Andrew R AR; Zeggini, Eleftheria E; Dunham, Ian I; Birney, Ewan E; Pasquali, Lorenzo L; Ferrer, Jorge J; Loos, Ruth J F RJ; Dupuis, Josée J; Florez, Jose C JC; Boerwinkle, Eric E; Pankow, James S JS; van Duijn, Cornelia C; Sijbrands, Eric E; Meigs, James B JB; Hu, Frank B FB; Thorsteinsdottir, Unnur U; Stefansson, Kari K; Lakka, Timo A TA; Rauramaa, Rainer R; Stumvoll, Michael M; Pedersen, Nancy L NL; Lind, Lars L; Keinanen-Kiukaanniemi, Sirkka M SM; Korpi-Hyövälti, Eeva E; Saaristo, Timo E TE; Saltevo, Juha J; Kuusisto, Johanna J; Laakso, Markku M; Metspalu, Andres A; Erbel, Raimund R; Jöcke, Karl-Heinz KH; Moebus, Susanne S; Ripatti, Samuli S; Salomaa, Veikko V; Ingelsson, Erik E; Boehm, Bernhard O BO; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Koistinen, Heikki H; Tuomilehto, Jaakko J; Hveem, Kristian K; Njølstad, Inger I; Deloukas, Panagiotis P; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; de Faire, Ulf U; Hamsten, Anders A; Illig, Thomas T; Peters, Annette A; Cauchi, Stephane S; Sladek, Rob R; Froguel, Philippe P; Hansen, Torben T; Pedersen, Oluf O; Morris, Andrew D AD; Palmer, Collin N A CN; Kathiresan, Sekar S; Melander, Olle O; Nilsson, Peter M PM; Groop, Leif C LC; Barroso, Inês I; Langenberg, Claudia C; Wareham, Nicholas J NJ; O'Callaghan, Christopher A CA; Gloyn, Anna L AL; Altshuler, David D; Boehnke, Michael M; Teslovich, Tanya M TM; McCarthy, Mark I MI; Morris, Andrew P AP; ,
Indications for potential parent-of-origin effects within the FTO gene.
Plos One
Liu, Xuanshi X; Hinney, Anke A; Scholz, Markus M; Scherag, André A; Tönjes, Anke A; Stumvoll, Michael M; Stadler, Peter F PF; Hebebrand, Johannes J; Böttcher, Yvonne Y
Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.
Plos One
Liu, Xuanshi X; Weidle, Kerstin K; Schröck, Kristin K; Tönjes, Anke A; Schleinitz, Dorit D; Breitfeld, Jana J; Stumvoll, Michael M; Böttcher, Yvonne Y; Schöneberg, Torsten T; Kovacs, Peter P
Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.
Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Low copy number of the salivary amylase gene predisposes to obesity.
Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.
Bmc Medical Genetics
Huhn, Stefanie S; Bevier, Melanie M; Rudolph, Anja A; Pardini, Barbara B; Naccarati, Alessio A; Hein, Rebecca R; Hoffmeister, Michael M; Vodickova, Ludmila L; Novotny, Jan J; Brenner, Hermann H; Chang-Claude, Jenny J; Hemminki, Kari K; Vodicka, Pavel P; Försti, Asta A
Implication of European-derived adiposity loci in African Americans.
International Journal Of Obesity (2005)
Hester, J M JM; Wing, M R MR; Li, J J; Palmer, N D ND; Xu, J J; Hicks, P J PJ; Roh, B H BH; Norris, J M JM; Wagenknecht, L E LE; Langefeld, C D CD; Freedman, B I BI; Bowden, D W DW; Ng, M C Y MC
The role of the fat mass and obesity associated gene (FTO) in breast cancer risk.
Bmc Medical Genetics
Kaklamani, Virginia V; Yi, Nengjun N; Sadim, Maureen M; Siziopikou, Kalliopi K; Zhang, Kui K; Xu, Yanfei Y; Tofilon, Sarah S; Agarwal, Surbhi S; Pasche, Boris B; Mantzoros, Christos C
Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study.
Bmc Proceedings
Li, Xiaohui X; Mei, Ling L; Yang, Kai K; Rotter, Jerome I JI; Guo, Xiuqing X
Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.
European Journal Of Human Genetics : Ejhg
Tönjes, Anke A; Zeggini, Eleftheria E; Kovacs, Peter P; Böttcher, Yvonne Y; Schleinitz, Dorit D; Dietrich, Kerstin K; Morris, Andrew P AP; Enigk, Beate B; Rayner, Nigel W NW; Koriath, Moritz M; Eszlinger, Markus M; Kemppinen, Anu A; Prokopenko, Inga I; Hoffmann, Katrin K; Teupser, Daniel D; Thiery, Joachim J; Krohn, Knut K; McCarthy, Mark I MI; Stumvoll, Michael M
FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.
Diabetes
Tan, Jonathan T JT; Dorajoo, Rajkumar R; Seielstad, Mark M; Sim, Xue Ling XL; Ong, Rick Twee-Hee RT; Chia, Kee Seng KS; Wong, Tien Yin TY; Saw, Seang Mei SM; Chew, Suok Kai SK; Aung, Tin T; Tai, E-Shyong ES
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.
Plos Genetics
Scuteri, Angelo A; Sanna, Serena S; Chen, Wei-Min WM; Uda, Manuela M; Albai, Giuseppe G; Strait, James J; Najjar, Samer S; Nagaraja, Ramaiah R; Orrú, Marco M; Usala, Gianluca G; Dei, Mariano M; Lai, Sandra S; Maschio, Andrea A; Busonero, Fabio F; Mulas, Antonella A; Ehret, Georg B GB; Fink, Ashley A AA; Weder, Alan B AB; Cooper, Richard S RS; Galan, Pilar P; Chakravarti, Aravinda A; Schlessinger, David D; Cao, Antonio A; Lakatta, Edward E; Abecasis, Gonçalo R GR