FTO c.46-43423C>G

Variant ID: 16-53800629-C-G

NM_001080432.2(FTO):c.46-43423C>G

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Association between sleep duration and metabolic syndrome: linear and nonlinear Mendelian randomization analyses.

Journal Of Translational Medicine
Liang, Yannis Yan YY; Chen, Jie J; Peng, Miaoguan M; Zhou, Jiajin J; Chen, Xinru X; Tan, Xiao X; Wang, Ningjian N; Ma, Huan H; Guo, Lan L; Zhang, Jihui J; Wing, Yun-Kwok YK; Geng, Qingshan Q; Ai, Sizhi S
Publication Date: 2023-02-07

Variant appearance in text: rs9940646
PubMed Link: 36747249
Variant Present in the following documents:
  • Main text
  • 12967_2023_Article_3920.pdf
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Longer sleep duration may negatively affect renal function.

International Urology And Nephrology
Mazidi, Mohsen M; Shekoohi, Niloofar N; Katsiki, Niki N; Banach, Maciej M
Publication Date: 2021-02

Variant appearance in text: rs9940646
PubMed Link: 32970283
Variant Present in the following documents:
  • Main text
  • 11255_2020_Article_2624.pdf
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The relationship between sleep duration, cognition and dementia: a Mendelian randomization study.

International Journal Of Epidemiology
Henry, Albert A; Katsoulis, Michail M; Masi, Stefano S; Fatemifar, Ghazaleh G; Denaxas, Spiros S; Acosta, Dionisio D; Garfield, Victoria V; Dale, Caroline E CE
Publication Date: 2019-06-01

Variant appearance in text: rs9940646
PubMed Link: 31062029
Variant Present in the following documents:
  • Main text
  • dyz071.pdf
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Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.

Nature Communications
Dashti, Hassan S HS; Jones, Samuel E SE; Wood, Andrew R AR; Lane, Jacqueline M JM; van Hees, Vincent T VT; Wang, Heming H; Rhodes, Jessica A JA; Song, Yanwei Y; Patel, Krunal K; Anderson, Simon G SG; Beaumont, Robin N RN; Bechtold, David A DA; Bowden, Jack J; Cade, Brian E BE; Garaulet, Marta M; Kyle, Simon D SD; Little, Max A MA; Loudon, Andrew S AS; Luik, Annemarie I AI; Scheer, Frank A J L FAJL; Spiegelhalder, Kai K; Tyrrell, Jessica J; Gottlieb, Daniel J DJ; Tiemeier, Henning H; Ray, David W DW; Purcell, Shaun M SM; Frayling, Timothy M TM; Redline, Susan S; Lawlor, Deborah A DA; Rutter, Martin K MK; Weedon, Michael N MN; Saxena, Richa R
Publication Date: 2019-03-07

Variant appearance in text: rs9940646
PubMed Link: 30846698
Variant Present in the following documents:
  • Main text
  • 41467_2019_Article_8917.pdf
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Complex Relationship between Obesity and the Fat Mass and Obesity Locus.

International Journal Of Biological Sciences
Yang, Qingyun Q; Xiao, Tiancun T; Guo, Jiao J; Su, Zhengquan Z
Publication Date: 2017

Variant appearance in text: rs9940646
PubMed Link: 28539834
Variant Present in the following documents:
  • Main text
  • ijbsv13p0615.pdf
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Nature Genetics
Gaulton, Kyle J KJ; Ferreira, Teresa T; Lee, Yeji Y; Raimondo, Anne A; Mägi, Reedik R; Reschen, Michael E ME; Mahajan, Anubha A; Locke, Adam A; Rayner, N William NW; Robertson, Neil N; Scott, Robert A RA; Prokopenko, Inga I; Scott, Laura J LJ; Green, Todd T; Sparso, Thomas T; Thuillier, Dorothee D; Yengo, Loic L; Grallert, Harald H; Wahl, Simone S; Frånberg, Mattias M; Strawbridge, Rona J RJ; Kestler, Hans H; Chheda, Himanshu H; Eisele, Lewin L; Gustafsson, Stefan S; Steinthorsdottir, Valgerdur V; Thorleifsson, Gudmar G; Qi, Lu L; Karssen, Lennart C LC; van Leeuwen, Elisabeth M EM; Willems, Sara M SM; Li, Man M; Chen, Han H; Fuchsberger, Christian C; Kwan, Phoenix P; Ma, Clement C; Linderman, Michael M; Lu, Yingchang Y; Thomsen, Soren K SK; Rundle, Jana K JK; Beer, Nicola L NL; van de Bunt, Martijn M; Chalisey, Anil A; Kang, Hyun Min HM; Voight, Benjamin F BF; Abecasis, Gonçalo R GR; Almgren, Peter P; Baldassarre, Damiano D; Balkau, Beverley B; Benediktsson, Rafn R; Blüher, Matthias M; Boeing, Heiner H; Bonnycastle, Lori L LL; Bottinger, Erwin P EP; Burtt, Noël P NP; Carey, Jason J; Charpentier, Guillaume G; Chines, Peter S PS; Cornelis, Marilyn C MC; Couper, David J DJ; Crenshaw, Andrew T AT; van Dam, Rob M RM; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Eriksson, Johan G JG; Esko, Tonu T; Eury, Elodie E; Fadista, João J; Flannick, Jason J; Fontanillas, Pierre P; Fox, Caroline C; Franks, Paul W PW; Gertow, Karl K; Gieger, Christian C; Gigante, Bruna B; Gottesman, Omri O; Grant, George B GB; Grarup, Niels N; Groves, Christopher J CJ; Hassinen, Maija M; Have, Christian T CT; Herder, Christian C; Holmen, Oddgeir L OL; Hreidarsson, Astradur B AB; Humphries, Steve E SE; Hunter, David J DJ; Jackson, Anne U AU; Jonsson, Anna A; Jørgensen, Marit E ME; Jørgensen, Torben T; Kao, Wen-Hong L WH; Kerrison, Nicola D ND; Kinnunen, Leena L; Klopp, Norman N; Kong, Augustine A; Kovacs, Peter P; Kraft, Peter P; Kravic, Jasmina J; Langford, Cordelia C; Leander, Karin K; Liang, Liming L; Lichtner, Peter P; Lindgren, Cecilia M CM; Lindholm, Eero E; Linneberg, Allan A; Liu, Ching-Ti CT; Lobbens, Stéphane S; Luan, Jian'an J; Lyssenko, Valeriya V; Männistö, Satu S; McLeod, Olga O; Meyer, Julia J; Mihailov, Evelin E; Mirza, Ghazala G; Mühleisen, Thomas W TW; Müller-Nurasyid, Martina M; Navarro, Carmen C; Nöthen, Markus M MM; Oskolkov, Nikolay N NN; Owen, Katharine R KR; Palli, Domenico D; Pechlivanis, Sonali S; Peltonen, Leena L; Perry, John R B JR; Platou, Carl G P CG; Roden, Michael M; Ruderfer, Douglas D; Rybin, Denis D; van der Schouw, Yvonne T YT; Sennblad, Bengt B; Sigurðsson, Gunnar G; Stančáková, Alena A; Steinbach, Gerald G; Storm, Petter P; Strauch, Konstantin K; Stringham, Heather M HM; Sun, Qi Q; Thorand, Barbara B; Tikkanen, Emmi E; Tonjes, Anke A; Trakalo, Joseph J; Tremoli, Elena E; Tuomi, Tiinamaija T; Wennauer, Roman R; Wiltshire, Steven S; Wood, Andrew R AR; Zeggini, Eleftheria E; Dunham, Ian I; Birney, Ewan E; Pasquali, Lorenzo L; Ferrer, Jorge J; Loos, Ruth J F RJ; Dupuis, Josée J; Florez, Jose C JC; Boerwinkle, Eric E; Pankow, James S JS; van Duijn, Cornelia C; Sijbrands, Eric E; Meigs, James B JB; Hu, Frank B FB; Thorsteinsdottir, Unnur U; Stefansson, Kari K; Lakka, Timo A TA; Rauramaa, Rainer R; Stumvoll, Michael M; Pedersen, Nancy L NL; Lind, Lars L; Keinanen-Kiukaanniemi, Sirkka M SM; Korpi-Hyövälti, Eeva E; Saaristo, Timo E TE; Saltevo, Juha J; Kuusisto, Johanna J; Laakso, Markku M; Metspalu, Andres A; Erbel, Raimund R; Jöcke, Karl-Heinz KH; Moebus, Susanne S; Ripatti, Samuli S; Salomaa, Veikko V; Ingelsson, Erik E; Boehm, Bernhard O BO; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Koistinen, Heikki H; Tuomilehto, Jaakko J; Hveem, Kristian K; Njølstad, Inger I; Deloukas, Panagiotis P; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; de Faire, Ulf U; Hamsten, Anders A; Illig, Thomas T; Peters, Annette A; Cauchi, Stephane S; Sladek, Rob R; Froguel, Philippe P; Hansen, Torben T; Pedersen, Oluf O; Morris, Andrew D AD; Palmer, Collin N A CN; Kathiresan, Sekar S; Melander, Olle O; Nilsson, Peter M PM; Groop, Leif C LC; Barroso, Inês I; Langenberg, Claudia C; Wareham, Nicholas J NJ; O'Callaghan, Christopher A CA; Gloyn, Anna L AL; Altshuler, David D; Boehnke, Michael M; Teslovich, Tanya M TM; McCarthy, Mark I MI; Morris, Andrew P AP; ,
Publication Date: 2015-12

Variant appearance in text: rs9940646
PubMed Link: 26551672
Variant Present in the following documents:
  • NIHMS65542-supplement-1.pdf
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Genome-wide association study of body mass index in subjects with alcohol dependence.

Addiction Biology
Polimanti, Renato R; Zhang, Huiping H; Smith, Andrew H AH; Zhao, Hongyu H; Farrer, Lindsay A LA; Kranzler, Henry R HR; Gelernter, Joel J
Publication Date: 2017-03

Variant appearance in text: rs9940646
PubMed Link: 26458734
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs9940646
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
  • fgene-05-00250.pdf
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Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs9940646
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



Genome-wide association analysis implicates elastic microfibrils in the development of nonsyndromic striae distensae.

The Journal Of Investigative Dermatology
Tung, Joyce Y JY; Kiefer, Amy K AK; Mullins, Meghan M; Francke, Uta U; Eriksson, Nicholas N
Publication Date: 2013-11

Variant appearance in text: rs9940646
PubMed Link: 23633020
Variant Present in the following documents:
  • jid2013196x1.pdf
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Variation in genes related to obesity, weight, and weight change and risk of contralateral breast cancer in the WECARE Study population.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Brooks, Jennifer D JD; Bernstein, Leslie L; Teraoka, Sharon N SN; Knight, Julia A JA; Mellemkjær, Lene L; John, Esther M EM; Malone, Kathleen E KE; Reiner, Anne S AS; Lynch, Charles F CF; Concannon, Patrick P; Haile, Robert W RW; Bernstein, Jonine L JL; ,
Publication Date: 2012-12

Variant appearance in text: rs9940646
PubMed Link: 23033454
Variant Present in the following documents:
  • Main text
View BVdb publication page



FTO gene variation and measures of body mass in an African population.

Bmc Medical Genetics
Hennig, Branwen J BJ; Fulford, Anthony J AJ; Sirugo, Giorgio G; Rayco-Solon, Pura P; Hattersley, Andrew T AT; Frayling, Timothy M TM; Prentice, Andrew M AM
Publication Date: 2009-03-05

Variant appearance in text: rs9940646
PubMed Link: 19265514
Variant Present in the following documents:
  • Main text
  • 1471-2350-10-21.pdf
View BVdb publication page