A genome-wide association study identifies a possible role for cannabinoid signalling in the pathogenesis of diabetic kidney disease.
Scientific Reports
Osman, Wael W; Mousa, Mira M; Albreiki, Mohammed M; Baalfaqih, Zahrah Z; Daggag, Hinda H; Hill, Claire C; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Al Safar, Habiba H
Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease.
Journal Of Cachexia, Sarcopenia And Muscle
Attaway, Amy H AH; Bellar, Annette A; Welch, Nicole N; Sekar, Jinendiran J; Kumar, Avinash A; Mishra, Saurabh S; Hatipoğlu, Umur U; McDonald, Merry-Lynn ML; Regan, Elizabeth A EA; Smith, Jonathan D JD; Washko, George G; Estépar, Raúl San José RSJ; Bazeley, Peter P; Zein, Joe J; Dasarathy, Srinivasan S
Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.
Nature Communications
Levin, Michael G MG; Tsao, Noah L NL; Singhal, Pankhuri P; Liu, Chang C; Vy, Ha My T HMT; Paranjpe, Ishan I; Backman, Joshua D JD; Bellomo, Tiffany R TR; Bone, William P WP; Biddinger, Kiran J KJ; Hui, Qin Q; Dikilitas, Ozan O; Satterfield, Benjamin A BA; Yang, Yifan Y; Morley, Michael P MP; Bradford, Yuki Y; Burke, Megan M; Reza, Nosheen N; Charest, Brian B; , ; Judy, Renae L RL; Puckelwartz, Megan J MJ; Hakonarson, Hakon H; Khan, Atlas A; Kottyan, Leah C LC; Kullo, Iftikhar I; Luo, Yuan Y; McNally, Elizabeth M EM; Rasmussen-Torvik, Laura J LJ; Day, Sharlene M SM; Do, Ron R; Phillips, Lawrence S LS; Ellinor, Patrick T PT; Nadkarni, Girish N GN; Ritchie, Marylyn D MD; Arany, Zoltan Z; Cappola, Thomas P TP; Margulies, Kenneth B KB; Aragam, Krishna G KG; Haggerty, Christopher M CM; Joseph, Jacob J; Sun, Yan V YV; Voight, Benjamin F BF; Damrauer, Scott M SM
Genome-Wide Association Analysis of Over 170,000 Individuals from the UK Biobank Identifies Seven Loci Associated with Dietary Approaches to Stop Hypertension (DASH) Diet.
Nutrients
Mompeo, Olatz O; Freidin, Maxim B MB; Gibson, Rachel R; Hysi, Pirro G PG; Christofidou, Paraskevi P; Segal, Eran E; Valdes, Ana M AM; Spector, Tim D TD; Menni, Cristina C; Mangino, Massimo M
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.
Nature Communications
Agrawal, Saaket S; Wang, Minxian M; Klarqvist, Marcus D R MDR; Smith, Kirk K; Shin, Joseph J; Dashti, Hesam H; Diamant, Nathaniel N; Choi, Seung Hoan SH; Jurgens, Sean J SJ; Ellinor, Patrick T PT; Philippakis, Anthony A; Claussnitzer, Melina M; Ng, Kenney K; Udler, Miriam S MS; Batra, Puneet P; Khera, Amit V AV
Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.
Nature Communications
Chen, Vincent L VL; Du, Xiaomeng X; Chen, Yanhua Y; Kuppa, Annapurna A; Handelman, Samuel K SK; Vohnoutka, Rishel B RB; Peyser, Patricia A PA; Palmer, Nicholette D ND; Bielak, Lawrence F LF; Halligan, Brian B; Speliotes, Elizabeth K EK
Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea.
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Nature Communications
Shah, Sonia S; Henry, Albert A; Roselli, Carolina C; Lin, Honghuang H; Sveinbjörnsson, Garðar G; Fatemifar, Ghazaleh G; Hedman, Åsa K ÅK; Wilk, Jemma B JB; Morley, Michael P MP; Chaffin, Mark D MD; Helgadottir, Anna A; Verweij, Niek N; Dehghan, Abbas A; Almgren, Peter P; Andersson, Charlotte C; Aragam, Krishna G KG; Ärnlöv, Johan J; Backman, Joshua D JD; Biggs, Mary L ML; Bloom, Heather L HL; Brandimarto, Jeffrey J; Brown, Michael R MR; Buckbinder, Leonard L; Carey, David J DJ; Chasman, Daniel I DI; Chen, Xing X; Chen, Xu X; Chung, Jonathan J; Chutkow, William W; Cook, James P JP; Delgado, Graciela E GE; Denaxas, Spiros S; Doney, Alexander S AS; Dörr, Marcus M; Dudley, Samuel C SC; Dunn, Michael E ME; Engström, Gunnar G; Esko, Tõnu T; Felix, Stephan B SB; Finan, Chris C; Ford, Ian I; Ghanbari, Mohsen M; Ghasemi, Sahar S; Giedraitis, Vilmantas V; Giulianini, Franco F; Gottdiener, John S JS; Gross, Stefan S; Guðbjartsson, Daníel F DF; Gutmann, Rebecca R; Haggerty, Christopher M CM; van der Harst, Pim P; Hyde, Craig L CL; Ingelsson, Erik E; Jukema, J Wouter JW; Kavousi, Maryam M; Khaw, Kay-Tee KT; Kleber, Marcus E ME; Køber, Lars L; Koekemoer, Andrea A; Langenberg, Claudia C; Lind, Lars L; Lindgren, Cecilia M CM; London, Barry B; Lotta, Luca A LA; Lovering, Ruth C RC; Luan, Jian'an J; Magnusson, Patrik P; Mahajan, Anubha A; Margulies, Kenneth B KB; März, Winfried W; Melander, Olle O; Mordi, Ify R IR; Morgan, Thomas T; Morris, Andrew D AD; Morris, Andrew P AP; Morrison, Alanna C AC; Nagle, Michael W MW; Nelson, Christopher P CP; Niessner, Alexander A; Niiranen, Teemu T; O'Donoghue, Michelle L ML; Owens, Anjali T AT; Palmer, Colin N A CNA; Parry, Helen M HM; Perola, Markus M; Portilla-Fernandez, Eliana E; Psaty, Bruce M BM; , ; Rice, Kenneth M KM; Ridker, Paul M PM; Romaine, Simon P R SPR; Rotter, Jerome I JI; Salo, Perttu P; Salomaa, Veikko V; van Setten, Jessica J; Shalaby, Alaa A AA; Smelser, Diane T DT; Smith, Nicholas L NL; Stender, Steen S; Stott, David J DJ; Svensson, Per P; Tammesoo, Mari-Liis ML; Taylor, Kent D KD; Teder-Laving, Maris M; Teumer, Alexander A; Thorgeirsson, Guðmundur G; Thorsteinsdottir, Unnur U; Torp-Pedersen, Christian C; Trompet, Stella S; Tyl, Benoit B; Uitterlinden, Andre G AG; Veluchamy, Abirami A; Völker, Uwe U; Voors, Adriaan A AA; Wang, Xiaosong X; Wareham, Nicholas J NJ; Waterworth, Dawn D; Weeke, Peter E PE; Weiss, Raul R; Wiggins, Kerri L KL; Xing, Heming H; Yerges-Armstrong, Laura M LM; Yu, Bing B; Zannad, Faiez F; Zhao, Jing Hua JH; Hemingway, Harry H; Samani, Nilesh J NJ; McMurray, John J V JJV; Yang, Jian J; Visscher, Peter M PM; Newton-Cheh, Christopher C; Malarstig, Anders A; Holm, Hilma H; Lubitz, Steven A SA; Sattar, Naveed N; Holmes, Michael V MV; Cappola, Thomas P TP; Asselbergs, Folkert W FW; Hingorani, Aroon D AD; Kuchenbaecker, Karoline K; Ellinor, Patrick T PT; Lang, Chim C CC; Stefansson, Kari K; Smith, J Gustav JG; Vasan, Ramachandran S RS; Swerdlow, Daniel I DI; Lumbers, R Thomas RT
Genetics of diabetic kidney disease: A follow-up study in the Arab population of the United Arab Emirates.
Molecular Genetics & Genomic Medicine
Osman, Wael M WM; Jelinek, Herbert F HF; Tay, Guan K GK; Hassan, Mohamed H MH; Almahmeed, Wael W; Khandoker, Ahsan H AH; Khalaf, Kinda K; Alsafar, Habiba S HS
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.
Human Molecular Genetics
Bradfield, Jonathan P JP; Vogelezang, Suzanne S; Felix, Janine F JF; Chesi, Alessandra A; Helgeland, Øyvind Ø; Horikoshi, Momoko M; Karhunen, Ville V; Lowry, Estelle E; Cousminer, Diana L DL; Ahluwalia, Tarunveer S TS; Thiering, Elisabeth E; Boh, Eileen Tai-Hui ET; Zafarmand, Mohammad H MH; Vilor-Tejedor, Natalia N; Wang, Carol A CA; Joro, Raimo R; Chen, Zhanghua Z; Gauderman, William J WJ; Pitkänen, Niina N; Parra, Esteban J EJ; Fernandez-Rhodes, Lindsay L; Alyass, Akram A; Monnereau, Claire C; Curtin, John A JA; Have, Christian T CT; McCormack, Shana E SE; Hollensted, Mette M; Frithioff-Bøjsøe, Christine C; Valladares-Salgado, Adan A; Peralta-Romero, Jesus J; Teo, Yik-Ying YY; Standl, Marie M; Leinonen, Jaakko T JT; Holm, Jens-Christian JC; Peters, Triinu T; Vioque, Jesus J; Vrijheid, Martine M; Simpson, Angela A; Custovic, Adnan A; Vaudel, Marc M; Canouil, Mickaël M; Lindi, Virpi V; Atalay, Mustafa M; Kähönen, Mika M; Raitakari, Olli T OT; van Schaik, Barbera D C BDC; Berkowitz, Robert I RI; Cole, Shelley A SA; Voruganti, V Saroja VS; Wang, Yujie Y; Highland, Heather M HM; Comuzzie, Anthony G AG; Butte, Nancy F NF; Justice, Anne E AE; Gahagan, Sheila S; Blanco, Estela E; Lehtimäki, Terho T; Lakka, Timo A TA; Hebebrand, Johannes J; Bonnefond, Amélie A; Grarup, Niels N; Froguel, Philippe P; Lyytikäinen, Leo-Pekka LP; Cruz, Miguel M; Kobes, Sayuko S; Hanson, Robert L RL; Zemel, Babette S BS; Hinney, Anke A; Teo, Koon K KK; Meyre, David D; North, Kari E KE; Gilliland, Frank D FD; Bisgaard, Hans H; Bustamante, Mariona M; Bonnelykke, Klaus K; Pennell, Craig E CE; Rivadeneira, Fernando F; Uitterlinden, André G AG; Baier, Leslie J LJ; Vrijkotte, Tanja G M TGM; Heinrich, Joachim J; Sørensen, Thorkild I A TIA; Saw, Seang-Mei SM; Pedersen, Oluf O; Hansen, Torben T; Eriksson, Johan J; Widén, Elisabeth E; McCarthy, Mark I MI; Njølstad, Pål R PR; Power, Christine C; Hyppönen, Elina E; Sebert, Sylvain S; Brown, Christopher D CD; Järvelin, Marjo-Riitta MR; Timpson, Nicholas J NJ; Johansson, Stefan S; Hakonarson, Hakon H; Jaddoe, Vincent W V VWV; , ; Grant, S F A SFA
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Nature Communications
Lu, Yingchang Y; Day, Felix R FR; Gustafsson, Stefan S; Buchkovich, Martin L ML; Na, Jianbo J; Bataille, Veronique V; Cousminer, Diana L DL; Dastani, Zari Z; Drong, Alexander W AW; Esko, Tõnu T; Evans, David M DM; Falchi, Mario M; Feitosa, Mary F MF; Ferreira, Teresa T; Hedman, Åsa K ÅK; Haring, Robin R; Hysi, Pirro G PG; Iles, Mark M MM; Justice, Anne E AE; Kanoni, Stavroula S; Lagou, Vasiliki V; Li, Rui R; Li, Xin X; Locke, Adam A; Lu, Chen C; Mägi, Reedik R; Perry, John R B JR; Pers, Tune H TH; Qi, Qibin Q; Sanna, Marianna M; Schmidt, Ellen M EM; Scott, William R WR; Shungin, Dmitry D; Teumer, Alexander A; Vinkhuyzen, Anna A E AA; Walker, Ryan W RW; Westra, Harm-Jan HJ; Zhang, Mingfeng M; Zhang, Weihua W; Zhao, Jing Hua JH; Zhu, Zhihong Z; Afzal, Uzma U; Ahluwalia, Tarunveer Singh TS; Bakker, Stephan J L SJ; Bellis, Claire C; Bonnefond, Amélie A; Borodulin, Katja K; Buchman, Aron S AS; Cederholm, Tommy T; Choh, Audrey C AC; Choi, Hyung Jin HJ; Curran, Joanne E JE; de Groot, Lisette C P G M LC; De Jager, Philip L PL; Dhonukshe-Rutten, Rosalie A M RA; Enneman, Anke W AW; Eury, Elodie E; Evans, Daniel S DS; Forsen, Tom T; Friedrich, Nele N; Fumeron, Frédéric F; Garcia, Melissa E ME; Gärtner, Simone S; Han, Bok-Ghee BG; Havulinna, Aki S AS; Hayward, Caroline C; Hernandez, Dena D; Hillege, Hans H; Ittermann, Till T; Kent, Jack W JW; Kolcic, Ivana I; Laatikainen, Tiina T; Lahti, Jari J; Mateo Leach, Irene I; Lee, Christine G CG; Lee, Jong-Young JY; Liu, Tian T; Liu, Youfang Y; Lobbens, Stéphane S; Loh, Marie M; Lyytikäinen, Leo-Pekka LP; Medina-Gomez, Carolina C; Michaëlsson, Karl K; Nalls, Mike A MA; Nielson, Carrie M CM; Oozageer, Laticia L; Pascoe, Laura L; Paternoster, Lavinia L; Polašek, Ozren O; Ripatti, Samuli S; Sarzynski, Mark A MA; Shin, Chan Soo CS; Narančić, Nina Smolej NS; Spira, Dominik D; Srikanth, Priya P; Steinhagen-Thiessen, Elisabeth E; Sung, Yun Ju YJ; Swart, Karin M A KM; Taittonen, Leena L; Tanaka, Toshiko T; Tikkanen, Emmi E; van der Velde, Nathalie N; van Schoor, Natasja M NM; Verweij, Niek N; Wright, Alan F AF; Yu, Lei L; Zmuda, Joseph M JM; Eklund, Niina N; Forrester, Terrence T; Grarup, Niels N; Jackson, Anne U AU; Kristiansson, Kati K; Kuulasmaa, Teemu T; Kuusisto, Johanna J; Lichtner, Peter P; Luan, Jian'an J; Mahajan, Anubha A; Männistö, Satu S; Palmer, Cameron D CD; Ried, Janina S JS; Scott, Robert A RA; Stancáková, Alena A; Wagner, Peter J PJ; Demirkan, Ayse A; Döring, Angela A; Gudnason, Vilmundur V; Kiel, Douglas P DP; Kühnel, Brigitte B; Mangino, Massimo M; Mcknight, Barbara B; Menni, Cristina C; O'Connell, Jeffrey R JR; Oostra, Ben A BA; Shuldiner, Alan R AR; Song, Kijoung K; Vandenput, Liesbeth L; van Duijn, Cornelia M CM; Vollenweider, Peter P; White, Charles C CC; Boehnke, Michael M; Boettcher, Yvonne Y; Cooper, Richard S RS; Forouhi, Nita G NG; Gieger, Christian C; Grallert, Harald H; Hingorani, Aroon A; Jørgensen, Torben T; Jousilahti, Pekka P; Kivimaki, Mika M; Kumari, Meena M; Laakso, Markku M; Langenberg, Claudia C; Linneberg, Allan A; Luke, Amy A; Mckenzie, Colin A CA; Palotie, Aarno A; Pedersen, Oluf O; Peters, Annette A; Strauch, Konstantin K; Tayo, Bamidele O BO; Wareham, Nicholas J NJ; Bennett, David A DA; Bertram, Lars L; Blangero, John J; Blüher, Matthias M; Bouchard, Claude C; Campbell, Harry H; Cho, Nam H NH; Cummings, Steven R SR; Czerwinski, Stefan A SA; Demuth, Ilja I; Eckardt, Rahel R; Eriksson, Johan G JG; Ferrucci, Luigi L; Franco, Oscar H OH; Froguel, Philippe P; Gansevoort, Ron T RT; Hansen, Torben T; Harris, Tamara B TB; Hastie, Nicholas N; Heliövaara, Markku M; Hofman, Albert A; Jordan, Joanne M JM; Jula, Antti A; Kähönen, Mika M; Kajantie, Eero E; Knekt, Paul B PB; Koskinen, Seppo S; Kovacs, Peter P; Lehtimäki, Terho T; Lind, Lars L; Liu, Yongmei Y; Orwoll, Eric S ES; Osmond, Clive C; Perola, Markus M; Pérusse, Louis L; Raitakari, Olli T OT; Rankinen, Tuomo T; Rao, D C DC; Rice, Treva K TK; Rivadeneira, Fernando F; Rudan, Igor I; Salomaa, Veikko V; Sørensen, Thorkild I A TI; Stumvoll, Michael M; Tönjes, Anke A; Towne, Bradford B; Tranah, Gregory J GJ; Tremblay, Angelo A; Uitterlinden, André G AG; van der Harst, Pim P; Vartiainen, Erkki E; Viikari, Jorma S JS; Vitart, Veronique V; Vohl, Marie-Claude MC; Völzke, Henry H; Walker, Mark M; Wallaschofski, Henri H; Wild, Sarah S; Wilson, James F JF; Yengo, Loïc L; Bishop, D Timothy DT; Borecki, Ingrid B IB; Chambers, John C JC; Cupples, L Adrienne LA; Dehghan, Abbas A; Deloukas, Panos P; Fatemifar, Ghazaleh G; Fox, Caroline C; Furey, Terrence S TS; Franke, Lude L; Han, Jiali J; Hunter, David J DJ; Karjalainen, Juha J; Karpe, Fredrik F; Kaplan, Robert C RC; Kooner, Jaspal S JS; McCarthy, Mark I MI; Murabito, Joanne M JM; Morris, Andrew P AP; Bishop, Julia A N JA; North, Kari E KE; Ohlsson, Claes C; Ong, Ken K KK; Prokopenko, Inga I; Richards, J Brent JB; Schadt, Eric E EE; Spector, Tim D TD; Widén, Elisabeth E; Willer, Cristen J CJ; Yang, Jian J; Ingelsson, Erik E; Mohlke, Karen L KL; Hirschhorn, Joel N JN; Pospisilik, John Andrew JA; Zillikens, M Carola MC; Lindgren, Cecilia C; Kilpeläinen, Tuomas Oskari TO; Loos, Ruth J F RJ
Low copy number of the salivary amylase gene predisposes to obesity.
Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P