FTO c.46-31528A>G

Variant ID: 16-53812524-A-G

NM_001080432.2(FTO):c.46-31528A>G

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population.

Genes
Chama-Avilés, Alonso A; Flores-Viveros, Karla Lucero KL; Cabrera-Ayala, Jorge Alberto JA; Aguilar-Galarza, Adriana A; García-Muñoz, Willebaldo W; Haddad-Talancón, Lorenza L; de Lourdes Anzures-Cortés, Ma M; Velázquez-Sánchez, Claudia C; Chávez-Servín, Jorge Luis JL; Anaya-Loyola, Miriam Aracely MA; García-Gasca, Teresa T; Rodríguez-García, Víctor Manuel VM; Moreno-Celis, Ulisses U
Publication Date: 2023-01-06

Variant appearance in text: rs16945088
PubMed Link: 36672899
Variant Present in the following documents:
  • Main text
  • genes-14-00159.pdf
View BVdb publication page



Functional genomic characterization of the FTO locus in African Americans.

Physiological Genomics
Gill, Richard R; Stratigopoulos, George G; Lee, Joseph H JH; Leibel, Rudolph L RL
Publication Date: 2019-11-01

Variant appearance in text: rs16945088
PubMed Link: 31530225
Variant Present in the following documents:
  • Main text
View BVdb publication page



From genetics and epigenetics to the future of precision treatment for obesity.

Gastroenterology Report
Sun, Xulong X; Li, Pengzhou P; Yang, Xiangwu X; Li, Weizheng W; Qiu, Xianjie X; Zhu, Shaihong S
Publication Date: 2017-11

Variant appearance in text: rs16945088
PubMed Link: 29230297
Variant Present in the following documents:
  • Main text
View BVdb publication page



Novel Common Variants Associated with Obesity and Type 2 Diabetes Detected Using a cFDR Method.

Scientific Reports
Zhang, Qiang Q; Wu, Ke-Hao KH; He, Jing-Yang JY; Zeng, Yong Y; Greenbaum, Jonathan J; Xia, Xin X; Liu, Hui-Min HM; Lv, Wan-Qiang WQ; Lin, Xu X; Zhang, Wei-Dong WD; Xi, Yuan-Lin YL; Shi, Xue-Zhong XZ; Sun, Chang-Qing CQ; Deng, Hong-Wen HW
Publication Date: 2017-11-27

Variant appearance in text: rs16945088
PubMed Link: 29180724
Variant Present in the following documents:
  • Main text
  • 41598_2017_Article_16722.pdf
View BVdb publication page



Assessing the Causality Factors in the Association between (Abdominal) Obesity and Physical Activity among the Newfoundland Population-A Mendelian Randomization Analysis.

Genetics & Epigenetics
Barning, Frank F; Abarin, Taraneh T
Publication Date: 2016

Variant appearance in text: rs16945088
PubMed Link: 27478388
Variant Present in the following documents:
  • Main text
  • geg-8-2016-015.pdf
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Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools.

Molecular Metabolism
Teo, Adrian Kee Keong AK; Gupta, Manoj K MK; Doria, Alessandro A; Kulkarni, Rohit N RN
Publication Date: 2015-09

Variant appearance in text: rs16945088
PubMed Link: 26413465
Variant Present in the following documents:
  • Main text
View BVdb publication page



Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.

Plos One
Liu, Xuanshi X; Weidle, Kerstin K; Schröck, Kristin K; Tönjes, Anke A; Schleinitz, Dorit D; Breitfeld, Jana J; Stumvoll, Michael M; Böttcher, Yvonne Y; Schöneberg, Torsten T; Kovacs, Peter P
Publication Date: 2015

Variant appearance in text: rs16945088
PubMed Link: 25647475
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effect of FTO Gene and Physical Activity Interaction on Trunk Fat Percentage Among the Newfoundland Population.

Genetics & Epigenetics
Payne, Anthony A; Cahill, Farrell F; Sun, Guang G; Loredo-Osti, J Concepción JC; Abarin, Taraneh T
Publication Date: 2014

Variant appearance in text: rs16945088
PubMed Link: 25512711
Variant Present in the following documents:
  • Main text
  • geg-6-2014-021.pdf
View BVdb publication page



Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs16945088
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
  • fgene-05-00250.pdf
View BVdb publication page



The sum of many parts: potential mechanisms for improvement in glucose homeostasis after bariatric surgery.

Current Diabetes Reports
Nguyen, Kim T KT; Korner, Judith J
Publication Date: 2014

Variant appearance in text: rs16945088
PubMed Link: 24705810
Variant Present in the following documents:
  • Main text
View BVdb publication page



Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs16945088
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

Plos One
Reitz, Christiane C; Tosto, Giuseppe G; Mayeux, Richard R; Luchsinger, Jose A JA; , ; ,
Publication Date: 2012

Variant appearance in text: rs16945088
PubMed Link: 23251365
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
Apalasamy, Y D YD; Ming, M F MF; Rampal, S S; Bulgiba, A A; Mohamed, Z Z
Publication Date: 2012-12

Variant appearance in text: rs16945088
PubMed Link: 22911346
Variant Present in the following documents:
  • Main text
  • 0100-879X-bjmbr-45-12-1119.pdf
View BVdb publication page



Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach.

Plos One
Lyngdoh, Tanica T; Vuistiner, Philippe P; Marques-Vidal, Pedro P; Rousson, Valentin V; Waeber, Gérard G; Vollenweider, Peter P; Bochud, Murielle M
Publication Date: 2012

Variant appearance in text: rs16945088
PubMed Link: 22723994
Variant Present in the following documents:
  • Main text
  • pone.0039321.pdf
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Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.

Annals Of Human Genetics
Karns, Rebekah R; Viali, Satupaitea S; Tuitele, John J; Sun, Guangyun G; Cheng, Hong H; Weeks, Daniel E DE; McGarvey, Stephen T ST; Deka, Ranjan R
Publication Date: 2012-01

Variant appearance in text: rs16945088
PubMed Link: 22084931
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.

Plos One
Zhang, Ge G; Karns, Rebekah R; Narancic, Nina Smolej NS; Sun, Guangyun G; Cheng, Hong H; Missoni, Sasa S; Durakovic, Zijad Z; Rudan, Pavao P; Chakraborty, Ranajit R; Deka, Ranjan R
Publication Date: 2010-04-28

Variant appearance in text: rs16945088
PubMed Link: 20442772
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.

European Journal Of Human Genetics : Ejhg
Tönjes, Anke A; Zeggini, Eleftheria E; Kovacs, Peter P; Böttcher, Yvonne Y; Schleinitz, Dorit D; Dietrich, Kerstin K; Morris, Andrew P AP; Enigk, Beate B; Rayner, Nigel W NW; Koriath, Moritz M; Eszlinger, Markus M; Kemppinen, Anu A; Prokopenko, Inga I; Hoffmann, Katrin K; Teupser, Daniel D; Thiery, Joachim J; Krohn, Knut K; McCarthy, Mark I MI; Stumvoll, Michael M
Publication Date: 2010-01

Variant appearance in text: rs16945088
PubMed Link: 19584900
Variant Present in the following documents:
  • Main text
View BVdb publication page



FTO gene variation and measures of body mass in an African population.

Bmc Medical Genetics
Hennig, Branwen J BJ; Fulford, Anthony J AJ; Sirugo, Giorgio G; Rayco-Solon, Pura P; Hattersley, Andrew T AT; Frayling, Timothy M TM; Prentice, Andrew M AM
Publication Date: 2009-03-05

Variant appearance in text: rs16945088
PubMed Link: 19265514
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.

Plos One
Grant, Struan F A SF; Li, Mingyao M; Bradfield, Jonathan P JP; Kim, Cecilia E CE; Annaiah, Kiran K; Santa, Erin E; Glessner, Joseph T JT; Casalunovo, Tracy T; Frackelton, Edward C EC; Otieno, F George FG; Shaner, Julie L JL; Smith, Ryan M RM; Imielinski, Marcin M; Eckert, Andrew W AW; Chiavacci, Rosetta M RM; Berkowitz, Robert I RI; Hakonarson, Hakon H
Publication Date: 2008-03-12

Variant appearance in text: rs16945088
PubMed Link: 18335027
Variant Present in the following documents:
  • Main text
  • pone.0001746.pdf
View BVdb publication page