FTO c.46-31438G>A

Variant ID: 16-53812614-G-A

NM_001080432.2(FTO):c.46-31438G>A

This variant was identified in 22 publications

View GRCh38 version.




Publications:


Development of a genetic risk score to predict the risk of hypertension in European adolescents from the HELENA study.

Frontiers In Cardiovascular Medicine
Pérez-Gimeno, Gloria G; Seral-Cortes, Miguel M; Sabroso-Lasa, Sergio S; Esteban, Luis Mariano LM; Lurbe, Empar E; Béghin, Laurent L; Gottrand, Frederic F; Meirhaeghe, Aline A; Muntaner, Manon M; Kafatos, Anthony A; Molnár, Dénes D; Leclercq, Catherine C; Widhalm, Kurt K; Kersting, Mathilde M; Nova, Esther E; Salazar-Tortosa, Diego F DF; Gonzalez-Gross, Marcela M; Breidenassel, Christina C; Sinningen, Kathrin K; De Ruyter, Thaïs T; Labayen, Idoia I; Rupérez, Azahara I AI; Bueno-Lozano, Gloria G; Moreno, Luis A LA
Publication Date: 2023

Variant appearance in text: rs8057044
PubMed Link: 37324619
Variant Present in the following documents:
  • Main text
  • fcvm-10-1118919.pdf
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Genetic Studies of Metabolic Syndrome in Arab Populations: A Systematic Review and Meta-Analysis.

Frontiers In Genetics
Al-Homedi, Zahrah Z; Afify, Nariman N; Memon, Mashal M; Alsafar, Habiba H; Tay, Guan G; Jelinek, Herbert F HF; Mousa, Mira M; Abu-Samra, Nadia N; Osman, Wael W
Publication Date: 2021

Variant appearance in text: rs8057044
PubMed Link: 34868209
Variant Present in the following documents:
  • Table3.pdf
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Genetic factors associated with obesity risks in a Kazakhstani population.

Bmj Nutrition, Prevention & Health
Razbekova, Madina M; Issanov, Alpamys A; Chan, Mei-Yen MY; Chan, Robbie R; Yerezhepov, Dauren D; Kozhamkulov, Ulan U; Akilzhanova, Ainur A; Chan, Chee-Kai CK
Publication Date: 2021

Variant appearance in text: rs8057044
PubMed Link: 34308116
Variant Present in the following documents:
  • Main text
  • bmjnph-2020-000139.pdf
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Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I.Family study and meta-analysis.

Scientific Reports
Nagrani, Rajini R; Foraita, Ronja R; Gianfagna, Francesco F; Iacoviello, Licia L; Marild, Staffan S; Michels, Nathalie N; Molnár, Dénes D; Moreno, Luis L; Russo, Paola P; Veidebaum, Toomas T; Ahrens, Wolfgang W; Marron, Manuela M
Publication Date: 2020-04-28

Variant appearance in text: rs8057044
PubMed Link: 32346024
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_64031.pdf
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Functional genomic characterization of the FTO locus in African Americans.

Physiological Genomics
Gill, Richard R; Stratigopoulos, George G; Lee, Joseph H JH; Leibel, Rudolph L RL
Publication Date: 2019-11-01

Variant appearance in text: rs8057044
PubMed Link: 31530225
Variant Present in the following documents:
  • Main text
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Genomics of Reproductive Traits and Cardiometabolic Disease Risk in African American Women.

Nursing Research
Hardy, Theresa M TM; Barcelona, Veronica V; Sun, Yan V YV; Taylor, Jacquelyn Y JY
Publication Date: 2019

Variant appearance in text: rs8057044
PubMed Link: 30570522
Variant Present in the following documents:
  • Main text
View BVdb publication page



Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach.

Journal Of The Neurological Sciences
Wang, Xia-Fang XF; Lin, Xu X; Li, Ding-You DY; Zhou, Rou R; Greenbaum, Jonathan J; Chen, Yuan-Cheng YC; Zeng, Chun-Ping CP; Peng, Lin-Ping LP; Wu, Ke-Hao KH; Ao, Zeng-Xin ZX; Lu, Jun-Min JM; Guo, Yan-Fang YF; Shen, Jie J; Deng, Hong-Wen HW
Publication Date: 2017-09-15

Variant appearance in text: rs8057044
PubMed Link: 28870582
Variant Present in the following documents:
  • Main text
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Conditional analysis of multiple quantitative traits based on marginal GWAS summary statistics.

Genetic Epidemiology
Deng, Yangqing Y; Pan, Wei W
Publication Date: 2017-07

Variant appearance in text: rs8057044
PubMed Link: 28464407
Variant Present in the following documents:
  • Main text
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Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools.

Molecular Metabolism
Teo, Adrian Kee Keong AK; Gupta, Manoj K MK; Doria, Alessandro A; Kulkarni, Rohit N RN
Publication Date: 2015-09

Variant appearance in text: rs8057044
PubMed Link: 26413465
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Rs7206790 and rs11644943 in FTO gene are associated with risk of obesity in Chinese school-age population.

Plos One
Xu, Yuyang Y; Ling, Jie J; Yang, Min M; Wang, Hao H; Zhang, Shuai S; Zhang, Xuhui X; Zhu, Yimin Y
Publication Date: 2014

Variant appearance in text: rs8057044
PubMed Link: 25251416
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs8057044
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
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Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

Plos One
Tan, Li-Jun LJ; Zhu, Hu H; He, Hao H; Wu, Ke-Hao KH; Li, Jian J; Chen, Xiang-Ding XD; Zhang, Ji-Gang JG; Shen, Hui H; Tian, Qing Q; Krousel-Wood, Marie M; Papasian, Christopher J CJ; Bouchard, Claude C; Pérusse, Louis L; Deng, Hong-Wen HW
Publication Date: 2014

Variant appearance in text: rs8057044
PubMed Link: 24879436
Variant Present in the following documents:
  • Main text
  • pone.0096149.pdf
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Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs8057044
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



Genetics of obesity and type 2 diabetes in African Americans.

Journal Of Obesity
McCormack, Shana S; Grant, Struan F A SF
Publication Date: 2013

Variant appearance in text: rs8057044
PubMed Link: 23577239
Variant Present in the following documents:
  • Main text
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A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

Plos Genetics
Peters, Ulrike U; North, Kari E KE; Sethupathy, Praveen P; Buyske, Steve S; Haessler, Jeff J; Jiao, Shuo S; Fesinmeyer, Megan D MD; Jackson, Rebecca D RD; Kuller, Lew H LH; Rajkovic, Aleksandar A; Lim, Unhee U; Cheng, Iona I; Schumacher, Fred F; Wilkens, Lynne L; Li, Rongling R; Monda, Keri K; Ehret, Georg G; Nguyen, Khanh-Dung H KD; Cooper, Richard R; Lewis, Cora E CE; Leppert, Mark M; Irvin, Marguerite R MR; Gu, C Charles CC; Houston, Denise D; Buzkova, Petra P; Ritchie, Marylyn M; Matise, Tara C TC; Le Marchand, Loic L; Hindorff, Lucia A LA; Crawford, Dana C DC; Haiman, Christopher A CA; Kooperberg, Charles C
Publication Date: 2013

Variant appearance in text: rs8057044
PubMed Link: 23341774
Variant Present in the following documents:
  • Main text
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Estimation of genetic effects on BMI during adolescence in an ethnically diverse cohort: The National Longitudinal Study of Adolescent Health.

Nutrition & Diabetes
Graff, M M; North, K E KE; Mohlke, K L KL; Lange, L A LA; Luo, J J; Harris, K M KM; Young, K L KL; Richardson, A S AS; Lange, E M EM; Gordon-Larsen, P P
Publication Date: 2012-09-24

Variant appearance in text: rs8057044
PubMed Link: 23168566
Variant Present in the following documents:
  • Main text
  • nutd201220a.pdf
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Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.

Annals Of Human Genetics
Karns, Rebekah R; Viali, Satupaitea S; Tuitele, John J; Sun, Guangyun G; Cheng, Hong H; Weeks, Daniel E DE; McGarvey, Stephen T ST; Deka, Ranjan R
Publication Date: 2012-01

Variant appearance in text: rs8057044
PubMed Link: 22084931
Variant Present in the following documents:
  • Main text
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Implication of European-derived adiposity loci in African Americans.

International Journal Of Obesity (2005)
Hester, J M JM; Wing, M R MR; Li, J J; Palmer, N D ND; Xu, J J; Hicks, P J PJ; Roh, B H BH; Norris, J M JM; Wagenknecht, L E LE; Langefeld, C D CD; Freedman, B I BI; Bowden, D W DW; Ng, M C Y MC
Publication Date: 2012-03

Variant appearance in text: rs8057044
PubMed Link: 21750520
Variant Present in the following documents:
  • Main text
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Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine.

Plos One
Tayo, Bamidele O BO; Teil, Marie M; Tong, Liping L; Qin, Huaizhen H; Khitrov, Gregory G; Zhang, Weijia W; Song, Quinbin Q; Gottesman, Omri O; Zhu, Xiaofeng X; Pereira, Alexandre C AC; Cooper, Richard S RS; Bottinger, Erwin P EP
Publication Date: 2011-05-04

Variant appearance in text: rs8057044
PubMed Link: 21573225
Variant Present in the following documents:
  • Main text
  • pone.0019166.pdf
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FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans.

Carcinogenesis
Nock, Nora L NL; Plummer, Sarah J SJ; Thompson, Cheryl L CL; Casey, Graham G; Li, Li L
Publication Date: 2011-05

Variant appearance in text: rs8057044
PubMed Link: 21317302
Variant Present in the following documents:
  • Main text
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Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

International Journal Of Obesity (2005)
Wing, M R MR; Ziegler, J M JM; Langefeld, C D CD; Roh, B H BH; Palmer, N D ND; Mayer-Davis, E J EJ; Rewers, M J MJ; Haffner, S M SM; Wagenknecht, L E LE; Bowden, D W DW
Publication Date: 2011-09

Variant appearance in text: rs8057044
PubMed Link: 21102551
Variant Present in the following documents:
  • Main text
View BVdb publication page



Fine mapping of the association with obesity at the FTO locus in African-derived populations.

Human Molecular Genetics
Hassanein, Mohamed T MT; Lyon, Helen N HN; Nguyen, Thutrang T TT; Akylbekova, Ermeg L EL; Waters, Kevin K; Lettre, Guillaume G; Tayo, Bamidele B; Forrester, Terrence T; Sarpong, Daniel F DF; Stram, Dan O DO; Butler, Johannah L JL; Wilks, Rainford R; Liu, Jiankang J; Le Marchand, Loic L; Kolonel, Laurence N LN; Zhu, Xiaofeng X; Henderson, Brian B; Cooper, Richard R; McKenzie, Colin C; Taylor, Herman A HA; Haiman, Christopher A CA; Hirschhorn, Joel N JN
Publication Date: 2010-07-15

Variant appearance in text: rs8057044
PubMed Link: 20430937
Variant Present in the following documents:
  • Main text
View BVdb publication page