FTO c.46-30602A>T

Variant ID: 16-53813450-A-T

NM_001080432.2(FTO):c.46-30602A>T

This variant was identified in 25 publications

View GRCh38 version.




Publications:


Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population.

Genes
Chama-Avilés, Alonso A; Flores-Viveros, Karla Lucero KL; Cabrera-Ayala, Jorge Alberto JA; Aguilar-Galarza, Adriana A; García-Muñoz, Willebaldo W; Haddad-Talancón, Lorenza L; de Lourdes Anzures-Cortés, Ma M; Velázquez-Sánchez, Claudia C; Chávez-Servín, Jorge Luis JL; Anaya-Loyola, Miriam Aracely MA; García-Gasca, Teresa T; Rodríguez-García, Víctor Manuel VM; Moreno-Celis, Ulisses U
Publication Date: 2023-01-06

Variant appearance in text: rs8043757
PubMed Link: 36672899
Variant Present in the following documents:
  • Main text
  • genes-14-00159.pdf
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FTO Common Obesity SNPs Interact with Actionable Environmental Factors: Physical Activity, Sugar-Sweetened Beverages and Wine Consumption.

Nutrients
Chermon, Danyel D; Birk, Ruth R
Publication Date: 2022-10-09

Variant appearance in text: rs8043757
PubMed Link: 36235854
Variant Present in the following documents:
  • Main text
  • nutrients-14-04202.pdf
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Genetic Background of Fetal Growth Restriction.

International Journal Of Molecular Sciences
Nowakowska, Beata Anna BA; Pankiewicz, Katarzyna K; Nowacka, Urszula U; Niemiec, Magdalena M; Kozłowski, Szymon S; Issat, Tadeusz T
Publication Date: 2021-12-21

Variant appearance in text: rs8043757
PubMed Link: 35008459
Variant Present in the following documents:
  • Main text
  • ijms-23-00036.pdf
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Genetic Background of Fetal Growth Restriction.

International Journal Of Molecular Sciences
Nowakowska, Beata Anna BA; Pankiewicz, Katarzyna K; Nowacka, Urszula U; Niemiec, Magdalena M; Kozłowski, Szymon S; Issat, Tadeusz T
Publication Date: 2021-12-21

Variant appearance in text: rs8043757
PubMed Link: 35008459
Variant Present in the following documents:
  • Main text
  • ijms-23-00036.pdf
View BVdb publication page



Suggestive Evidence for Causal Effect of Leptin Levels on Risk for Anorexia Nervosa: Results of a Mendelian Randomization Study.

Frontiers In Genetics
Peters, Triinu T; Antel, Jochen J; Naaresh, Roaa R; Laabs, Björn-Hergen BH; Föcker, Manuel M; Albers, Nicola N; Bühlmeier, Judith J; Hinney, Anke A; Libuda, Lars L; Hebebrand, Johannes J
Publication Date: 2021

Variant appearance in text: rs8043757
PubMed Link: 34594363
Variant Present in the following documents:
  • Main text
  • fgene-12-733606.pdf
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Serum anti-inflammatory and inflammatory markers have no causal impact on telomere length: a Mendelian randomization study.

Archives Of Medical Science : Ams
Mazidi, Mohsen M; Shekoohi, Niloofar N; Katsiki, Niki N; Rakowski, Michal M; Mikhailidis, Dimitri P DP; Banach, Maciej M
Publication Date: 2021

Variant appearance in text: rs8043757
PubMed Link: 34025845
Variant Present in the following documents:
  • Main text
  • AMS-17-3-119965.pdf
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Effects of FTO and PPARγ variants on intrauterine growth restriction in a Brazilian birth cohort.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
Barbieri, M R MR; Fontes, A M AM; Barbieri, M A MA; Saraiva, M C P MCP; Simões, V M F VMF; Silva, A A M da AAMD; Abraham, K J KJ; Bettiol, H H
Publication Date: 2021

Variant appearance in text: rs8043757
PubMed Link: 33729310
Variant Present in the following documents:
  • Main text
  • 1414-431X-bjmbr-54-1-e10465.pdf
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Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea.

Cancer Research And Treatment
Hoang, Tung T; Song, Dayoung D; Lee, Jeonghee J; Lee, Eun Kyung EK; Hwangbo, Yul Y; Kim, Jeongseon J
Publication Date: 2021-07

Variant appearance in text: rs8043757
PubMed Link: 33285050
Variant Present in the following documents:
  • Main text
  • crt-2020-720.pdf
View BVdb publication page



Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies.

Scientific Reports
Ran, Shu S; Jiang, Zi-Xuan ZX; He, Xiao X; Liu, Yu Y; Zhang, Yu-Xue YX; Zhang, Lei L; Pei, Yu-Fang YF; Zhang, Meng M; Hai, Rong R; Gu, Gui-Shan GS; Liu, Bao-Lin BL; Tian, Qing Q; Zhang, Yong-Hong YH; Wang, Jing-Yu JY; Deng, Hong-Wen HW
Publication Date: 2020-03-19

Variant appearance in text: rs8043757
PubMed Link: 32193455
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_61406.pdf
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Association between impulsivity traits and body mass index at the observational and genetic epidemiology level.

Scientific Reports
Meyre, David D; Mohamed, Sebat S; Gray, Joshua C JC; Weafer, Jessica J; MacKillop, James J; de Wit, Harriet H
Publication Date: 2019-11-26

Variant appearance in text: rs8043757
PubMed Link: 31772290
Variant Present in the following documents:
  • Main text
View BVdb publication page



Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects.

Nutrients
Ortega-Azorín, Carolina C; Coltell, Oscar O; Asensio, Eva M EM; Sorlí, Jose V JV; González, José I JI; Portolés, Olga O; Saiz, Carmen C; Estruch, Ramon R; Ramírez-Sabio, Judith B JB; Pérez-Fidalgo, Alejandro A; Ordovas, Jose M JM; Corella, Dolores D
Publication Date: 2019-11-13

Variant appearance in text: rs8043757
PubMed Link: 31766143
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between genetically determined leptin and blood lipids considering alcohol consumption: a Mendelian randomisation study.

Bmj Open
Shen, Luqi L; Cordero, José F JF; Wang, Jia-Sheng JS; Shen, Ye Y; Li, Shengxu S; Liang, Lirong L; Zou, Zhiyong Z; Li, Changwei C
Publication Date: 2019-11-07

Variant appearance in text: rs8043757
PubMed Link: 31699712
Variant Present in the following documents:
  • Main text
  • bmjopen-2018-026860.draft_revisions.pdf
  • bmjopen-2018-026860.pdf
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FTO haplotyping underlines high obesity risk for European populations.

Bmc Medical Genomics
Babenko, Vladimir V; Babenko, Roman R; Gamieldien, Junaid J; Markel, Arcady A
Publication Date: 2019-03-13

Variant appearance in text: rs8043757
PubMed Link: 30871540
Variant Present in the following documents:
  • Main text
  • 12920_2019_Article_491.pdf
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Complex Relationship between Obesity and the Fat Mass and Obesity Locus.

International Journal Of Biological Sciences
Yang, Qingyun Q; Xiao, Tiancun T; Guo, Jiao J; Su, Zhengquan Z
Publication Date: 2017

Variant appearance in text: rs8043757
PubMed Link: 28539834
Variant Present in the following documents:
  • Main text
  • ijbsv13p0615.pdf
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Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.

Cancer Epidemiology
Yang, Baiyu B; Thrift, Aaron P AP; Figueiredo, Jane C JC; Jenkins, Mark A MA; Schumacher, Fredrick R FR; Conti, David V DV; Lin, Yi Y; Win, Aung Ko AK; Limburg, Paul J PJ; Berndt, Sonja I SI; Brenner, Hermann H; Chan, Andrew T AT; Chang-Claude, Jenny J; Hoffmeister, Michael M; Hudson, Thomas J TJ; Marchand, Loïc Le LL; Newcomb, Polly A PA; Slattery, Martha L ML; White, Emily E; Peters, Ulrike U; Casey, Graham G; Campbell, Peter T PT
Publication Date: 2016-10

Variant appearance in text: rs8043757
PubMed Link: 27449576
Variant Present in the following documents:
  • Main text
View BVdb publication page



Detection and interpretation of shared genetic influences on 42 human traits.

Nature Genetics
Pickrell, Joseph K JK; Berisa, Tomaz T; Liu, Jimmy Z JZ; Ségurel, Laure L; Tung, Joyce Y JY; Hinds, David A DA
Publication Date: 2016-07

Variant appearance in text: rs8043757
PubMed Link: 27182965
Variant Present in the following documents:
  • NIHMS780506-supplement-3.pdf
  • NIHMS780506-supplement-7.pdf
View BVdb publication page



A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders.

Cell Reports
Wang, Xuting X; Campbell, Michelle R MR; Lacher, Sarah E SE; Cho, Hye-Youn HY; Wan, Ma M; Crowl, Christopher L CL; Chorley, Brian N BN; Bond, Gareth L GL; Kleeberger, Steven R SR; Slattery, Matthew M; Bell, Douglas A DA
Publication Date: 2016-04-26

Variant appearance in text: rs8043757
PubMed Link: 27149848
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Nature Communications
Kilpeläinen, Tuomas O TO; Carli, Jayne F Martin JF; Skowronski, Alicja A AA; Sun, Qi Q; Kriebel, Jennifer J; Feitosa, Mary F MF; Hedman, Åsa K ÅK; Drong, Alexander W AW; Hayes, James E JE; Zhao, Jinghua J; Pers, Tune H TH; Schick, Ursula U; Grarup, Niels N; Kutalik, Zoltán Z; Trompet, Stella S; Mangino, Massimo M; Kristiansson, Kati K; Beekman, Marian M; Lyytikäinen, Leo-Pekka LP; Eriksson, Joel J; Henneman, Peter P; Lahti, Jari J; Tanaka, Toshiko T; Luan, Jian'an J; Del Greco M, Fabiola F; Pasko, Dorota D; Renström, Frida F; Willems, Sara M SM; Mahajan, Anubha A; Rose, Lynda M LM; Guo, Xiuqing X; Liu, Yongmei Y; Kleber, Marcus E ME; Pérusse, Louis L; Gaunt, Tom T; Ahluwalia, Tarunveer S TS; Ju Sung, Yun Y; Ramos, Yolande F YF; Amin, Najaf N; Amuzu, Antoinette A; Barroso, Inês I; Bellis, Claire C; Blangero, John J; Buckley, Brendan M BM; Böhringer, Stefan S; I Chen, Yii-Der YD; de Craen, Anton J N AJ; Crosslin, David R DR; Dale, Caroline E CE; Dastani, Zari Z; Day, Felix R FR; Deelen, Joris J; Delgado, Graciela E GE; Demirkan, Ayse A; Finucane, Francis M FM; Ford, Ian I; Garcia, Melissa E ME; Gieger, Christian C; Gustafsson, Stefan S; Hallmans, Göran G; Hankinson, Susan E SE; Havulinna, Aki S AS; Herder, Christian C; Hernandez, Dena D; Hicks, Andrew A AA; Hunter, David J DJ; Illig, Thomas T; Ingelsson, Erik E; Ioan-Facsinay, Andreea A; Jansson, John-Olov JO; Jenny, Nancy S NS; Jørgensen, Marit E ME; Jørgensen, Torben T; Karlsson, Magnus M; Koenig, Wolfgang W; Kraft, Peter P; Kwekkeboom, Joanneke J; Laatikainen, Tiina T; Ladwig, Karl-Heinz KH; LeDuc, Charles A CA; Lowe, Gordon G; Lu, Yingchang Y; Marques-Vidal, Pedro P; Meisinger, Christa C; Menni, Cristina C; Morris, Andrew P AP; Myers, Richard H RH; Männistö, Satu S; Nalls, Mike A MA; Paternoster, Lavinia L; Peters, Annette A; Pradhan, Aruna D AD; Rankinen, Tuomo T; Rasmussen-Torvik, Laura J LJ; Rathmann, Wolfgang W; Rice, Treva K TK; Brent Richards, J J; Ridker, Paul M PM; Sattar, Naveed N; Savage, David B DB; Söderberg, Stefan S; Timpson, Nicholas J NJ; Vandenput, Liesbeth L; van Heemst, Diana D; Uh, Hae-Won HW; Vohl, Marie-Claude MC; Walker, Mark M; Wichmann, Heinz-Erich HE; Widén, Elisabeth E; Wood, Andrew R AR; Yao, Jie J; Zeller, Tanja T; Zhang, Yiying Y; Meulenbelt, Ingrid I; Kloppenburg, Margreet M; Astrup, Arne A; Sørensen, Thorkild I A TI; Sarzynski, Mark A MA; Rao, D C DC; Jousilahti, Pekka P; Vartiainen, Erkki E; Hofman, Albert A; Rivadeneira, Fernando F; Uitterlinden, André G AG; Kajantie, Eero E; Osmond, Clive C; Palotie, Aarno A; Eriksson, Johan G JG; Heliövaara, Markku M; Knekt, Paul B PB; Koskinen, Seppo S; Jula, Antti A; Perola, Markus M; Huupponen, Risto K RK; Viikari, Jorma S JS; Kähönen, Mika M; Lehtimäki, Terho T; Raitakari, Olli T OT; Mellström, Dan D; Lorentzon, Mattias M; Casas, Juan P JP; Bandinelli, Stefanie S; März, Winfried W; Isaacs, Aaron A; van Dijk, Ko W KW; van Duijn, Cornelia M CM; Harris, Tamara B TB; Bouchard, Claude C; Allison, Matthew A MA; Chasman, Daniel I DI; Ohlsson, Claes C; Lind, Lars L; Scott, Robert A RA; Langenberg, Claudia C; Wareham, Nicholas J NJ; Ferrucci, Luigi L; Frayling, Timothy M TM; Pramstaller, Peter P PP; Borecki, Ingrid B IB; Waterworth, Dawn M DM; Bergmann, Sven S; Waeber, Gérard G; Vollenweider, Peter P; Vestergaard, Henrik H; Hansen, Torben T; Pedersen, Oluf O; Hu, Frank B FB; Eline Slagboom, P P; Grallert, Harald H; Spector, Tim D TD; Jukema, J W JW; Klein, Robert J RJ; Schadt, Erik E EE; Franks, Paul W PW; Lindgren, Cecilia M CM; Leibel, Rudolph L RL; Loos, Ruth J F RJ
Publication Date: 2016-02-01

Variant appearance in text: rs8043757
PubMed Link: 26833098
Variant Present in the following documents:
  • ncomms10494.pdf
  • ncomms10494-s1.pdf
View BVdb publication page



Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs8043757
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
View BVdb publication page



Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

Plos One
Tan, Li-Jun LJ; Zhu, Hu H; He, Hao H; Wu, Ke-Hao KH; Li, Jian J; Chen, Xiang-Ding XD; Zhang, Ji-Gang JG; Shen, Hui H; Tian, Qing Q; Krousel-Wood, Marie M; Papasian, Christopher J CJ; Bouchard, Claude C; Pérusse, Louis L; Deng, Hong-Wen HW
Publication Date: 2014

Variant appearance in text: rs8043757
PubMed Link: 24879436
Variant Present in the following documents:
  • Main text
  • pone.0096149.pdf
View BVdb publication page



Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs8043757
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



Genome-wide association analysis implicates elastic microfibrils in the development of nonsyndromic striae distensae.

The Journal Of Investigative Dermatology
Tung, Joyce Y JY; Kiefer, Amy K AK; Mullins, Meghan M; Francke, Uta U; Eriksson, Nicholas N
Publication Date: 2013-11

Variant appearance in text: rs8043757
PubMed Link: 23633020
Variant Present in the following documents:
  • jid2013196x1.pdf
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Absence of association between specific common variants of the obesity-related FTO gene and psychological and behavioral eating disorder phenotypes.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Jonassaint, Charles R CR; Szatkiewicz, Jin Peng JP; Bulik, Cynthia M CM; Thornton, Laura M LM; Bloss, Cinnamon C; Berrettini, Wade H WH; Kaye, Walter H WH; Bergen, Andrew W AW; Magistretti, Pierre P; Strober, Michael M; Keel, Pamela K PK; Brandt, Harry H; Crawford, Steve S; Crow, Scott S; Fichter, Manfred M MM; Goldman, David D; Halmi, Katherine A KA; Johnson, Craig C; Kaplan, Allan S AS; Klump, Kelly L KL; La Via, Maria M; Mitchell, James E JE; Rotondo, Alessandro A; Treasure, Janet J; Woodside, D Blake DB
Publication Date: 2011-06

Variant appearance in text: rs8043757
PubMed Link: 21438147
Variant Present in the following documents:
  • Main text
View BVdb publication page



Variations in the FTO gene are associated with severe obesity in the Japanese.

Journal Of Human Genetics
Hotta, Kikuko K; Nakata, Yoshio Y; Matsuo, Tomoaki T; Kamohara, Seika S; Kotani, Kazuaki K; Komatsu, Ryoya R; Itoh, Naoto N; Mineo, Ikuo I; Wada, Jun J; Masuzaki, Hiroaki H; Yoneda, Masato M; Nakajima, Atsushi A; Miyazaki, Shigeru S; Tokunaga, Katsuto K; Kawamoto, Manabu M; Funahashi, Tohru T; Hamaguchi, Kazuyuki K; Yamada, Kentaro K; Hanafusa, Toshiaki T; Oikawa, Shinichi S; Yoshimatsu, Hironobu H; Nakao, Kazuwa K; Sakata, Toshiie T; Matsuzawa, Yuji Y; Tanaka, Kiyoji K; Kamatani, Naoyuki N; Nakamura, Yusuke Y
Publication Date: 2008

Variant appearance in text: rs8043757
PubMed Link: 18379722
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Plos Genetics
Scuteri, Angelo A; Sanna, Serena S; Chen, Wei-Min WM; Uda, Manuela M; Albai, Giuseppe G; Strait, James J; Najjar, Samer S; Nagaraja, Ramaiah R; Orrú, Marco M; Usala, Gianluca G; Dei, Mariano M; Lai, Sandra S; Maschio, Andrea A; Busonero, Fabio F; Mulas, Antonella A; Ehret, Georg B GB; Fink, Ashley A AA; Weder, Alan B AB; Cooper, Richard S RS; Galan, Pilar P; Chakravarti, Aravinda A; Schlessinger, David D; Cao, Antonio A; Lakatta, Edward E; Abecasis, Gonçalo R GR
Publication Date: 2007-07

Variant appearance in text: rs8043757
PubMed Link: 17658951
Variant Present in the following documents:
  • pgen.0030115.pdf
View BVdb publication page